KEGG   Plecotus auritus (brown big-eared bat): 308245348
Entry
308245348         CDS       T11911                                 
Symbol
TBK1, AC0HY7_012181
Name
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
pots  Plecotus auritus (brown big-eared bat)
Pathway
pots04014  Ras signaling pathway
pots04137  Mitophagy - animal
pots04140  Autophagy - animal
pots04620  Toll-like receptor signaling pathway
pots04621  NOD-like receptor signaling pathway
pots04622  RIG-I-like receptor signaling pathway
pots04623  Cytosolic DNA-sensing pathway
pots04657  IL-17 signaling pathway
pots04936  Alcoholic liver disease
pots05014  Amyotrophic lateral sclerosis
pots05022  Pathways of neurodegeneration - multiple diseases
pots05135  Yersinia infection
pots05160  Hepatitis C
pots05161  Hepatitis B
pots05162  Measles
pots05163  Human cytomegalovirus infection
pots05164  Influenza A
pots05165  Human papillomavirus infection
pots05167  Kaposi sarcoma-associated herpesvirus infection
pots05168  Herpes simplex virus 1 infection
pots05169  Epstein-Barr virus infection
pots05170  Human immunodeficiency virus 1 infection
pots05171  Coronavirus disease
pots05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pots00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    308245348 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    308245348 (TBK1)
   04137 Mitophagy - animal
    308245348 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    308245348 (TBK1)
   04621 NOD-like receptor signaling pathway
    308245348 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    308245348 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    308245348 (TBK1)
   04657 IL-17 signaling pathway
    308245348 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    308245348 (TBK1)
   05161 Hepatitis B
    308245348 (TBK1)
   05160 Hepatitis C
    308245348 (TBK1)
   05171 Coronavirus disease
    308245348 (TBK1)
   05164 Influenza A
    308245348 (TBK1)
   05162 Measles
    308245348 (TBK1)
   05168 Herpes simplex virus 1 infection
    308245348 (TBK1)
   05163 Human cytomegalovirus infection
    308245348 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    308245348 (TBK1)
   05169 Epstein-Barr virus infection
    308245348 (TBK1)
   05165 Human papillomavirus infection
    308245348 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    308245348 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    308245348 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    308245348 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    308245348 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    308245348 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pots01001]
    308245348 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pots04131]
    308245348 (TBK1)
Enzymes [BR:pots01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     308245348 (TBK1)
Protein kinases [BR:pots01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   308245348 (TBK1)
Membrane trafficking [BR:pots04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    308245348 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 CEP63 DUF713 Kinase-like COG6_N
Other DBs
NCBI-GeneID: 308245348
NCBI-ProteinID: XP_080518605
LinkDB
Position
3:complement(163274863..163322039)
AA seq 728 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLYAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISANQELIYEGRRLV
LEPGRLVQHFPKTTEENPIFVISREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIAGTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLEFCLRSIQSMKV
YEKLLKTNLEATDLDEISDIHTKLLRLSSSRGTIETNLQDIESKLSPGGLLSDTWAHQEG
THPKDRHVEKLQVLLNWITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHF
TDECVKKYETFLDKSEEWMRKMLHLKKQLLSLTNQCLDIEEEISKYQDYTNELQETLPQK
MFAASSGIKHTMAPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDG
GLRNVDCL
NT seq 2187 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatatgctatcaaagtattt
aataacataagcttccttcgtccagtagatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgcgggagtttatacactgttttagaagag
ccatctaatgcctatggactgccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatcttcgagaaaacggcatagtccaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagacgggcaatctgtatacaaactcaccgattttggtgca
gctagagaattagaagatgatgagcagtttgtttctttgtatggcacagaagaatatttg
catcctgatatgtatgagagggcagtgctaaggaaagatcatcagaagaaatatggagca
acagttgatctttggagcatcggggtaactttttaccatgcagctactgggtcactgcca
tttaggccatttgaagggccacgtaggaataaggaggtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctatttcttgtagtctttctcggggtcttcaagttctacttacccctgtc
ctggcaaacatccttgaggctgatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccggatgataattcatgttttctcactacaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttctgcaaatcaagaacttatatatgaaggacgccgcttagtt
ctagaacctggaagactagtacagcatttccctaaaactactgaggaaaatcctatcttt
gtaataagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttatgacttagatggagatgctagcatggctaaggcaattacagga
gttgtgtgttatgcctgtagaattgccggtaccttgctgctttatcaggaattgatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgtccacaaa
aagacagaagttgtgatcacattggaattctgcctcagaagcattcaaagtatgaaagta
tatgaaaagttgttgaaaaccaacctagaagcaacagacttagatgaaatttcagacata
cacaccaaattgttgagactttccagttctcggggaacaatagaaaccaatcttcaggat
atcgaaagcaagttatctccaggtggattgctgtcagatacatgggcccatcaagaaggc
actcatccaaaagatagacatgtagaaaagctacaagtcctgttaaattggatcacagag
atttactatcaattcaaaaaagacaaagcagaacgtagattagcttataatgaagaacag
atccacaaatttgataagcaaaaactgtattaccatgcaacaaaagcaatgacccacttc
acagatgaatgtgttaaaaagtacgagacatttttggataagtcagaagaatggatgaga
aagatgcttcatcttaagaagcagttgttatccctaactaatcagtgtttagatattgaa
gaagaaatatcaaagtatcaagactatactaatgagttacaagaaactttgcctcagaaa
atgtttgcagcctccagtggaatcaaacataccatggctccaatttatccatgttctaac
acattagtagaaatgactcttggtatgaagaaattaaaagaagaaatggaaggggtggtt
aaagaacttgctgaaaataaccatattttagaaagatttggctctttaaccatggatggt
ggccttcgcaatgttgactgtctttag

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