Plecotus auritus (brown big-eared bat): 308254317
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Entry
308254317 CDS
T11911
Symbol
PDE8B, AC0HY7_021150
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 5
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pots Plecotus auritus (brown big-eared bat)
Pathway
pots00230
Purine metabolism
pots01100
Metabolic pathways
pots04927
Cortisol synthesis and secretion
pots04934
Cushing syndrome
pots05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pots00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
308254317 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
308254317 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
308254317 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
308254317 (PDE8B)
Enzymes [BR:
pots01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
308254317 (PDE8B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
Motif
Other DBs
NCBI-GeneID:
308254317
NCBI-ProteinID:
XP_080536407
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Position
7:complement(134866475..135087237)
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AA seq
886 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPHHTTSVSQGPEPPLPGLSVQTDAADAIPRSRESG
PPSAARVRRARAELGSSSSSSGSAAPAATTCRGRRRHCCSSAEAETQTNYSNLQQVSSAE
VRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGFRCNIARTPESALECFLDKHHEI
IVIDHRQARNFSAEAVCRSIRATNLAEHTVILAVVSQASGDHEEASVLPLLHAGFSRRFM
ENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDEHVIQYVNPAFE
RMMGYHKSELLGKELAELPKSDKNRADLLDTINTCIRKGKEWQGVYYAKRKSGDSIQQHV
KITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTESHSFRYKSRRRESID
VKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVL
EILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPIT
INDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLRCSETTLRA
WLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDH
PGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQA
IIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPIGKNFPENQILIKRMMIKC
ADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDY
FITDMFDAWDAFAHLPALMQHLANNYKHWKTLDDLKCKSLRLPSDS
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtttcgcagagcggcgtgatctactgtcgggactcg
gacgagtccaactcgccccaccatactaccagcgtgtcgcagggccccgaacctcccttg
cccggcctctctgtgcagaccgacgccgccgacgccatcccccggagccgcgagtccggg
cctcccagcgccgcccgggtccgcagggctcgcgccgagctgggcagcagcagcagcagc
tcgggctctgcagccccagcggcgaccacctgcaggggccggaggcgccactgctgcagc
agcgcggaggccgagacccagaccaactactccaacctccagcaggtgtcttctgcggag
gtacgcattgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcc
aaggaggacagtcagagtgatggattctggtgggcctgtgacagagccggtttcagatgc
aacatcgcccggactccagagtcagcccttgaatgctttctggataaacatcatgaaatt
attgtgatcgatcacagacaggctcggaacttcagtgcagaggctgtgtgcaggtcgatc
cgggccacaaatctcgcggagcacacggtgatcctcgcggtggtttcacaagcatcgggc
gaccatgaagaggcctcagtcctccctcttctgcacgcaggcttcagcaggagatttatg
gagaatagcagcatcattgcctgctataatgaactgattcaaatagagcatggggaagtt
cgctcgcagtttaaactccgggcttgtaattcagtgtttacagcattagaccactgtcat
gaagccatagaaataacaagcgatgagcatgtgattcagtatgtcaacccagccttcgaa
aggatgatgggctaccacaagagcgagctcctcgggaaagaactcgccgagctgcccaaa
agtgataagaaccgggcagacctcctcgacaccatcaacacgtgcatcaggaagggcaag
gagtggcaaggggtttactacgccaaaaggaagtctggggacagcatccaacagcacgtg
aagatcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaa
ctgtgttgtaccactgacaataataagcagattcacaagattcatcgagattcaggagac
aattctcagacagagtctcattcattcagatacaagagcaggaggagggagtccattgat
gtgaaatcgatatcatctcgaggcagtgatgcgccaagcctgcagaaccgtcgctatcca
tccatggcaaggatccattccatgaccatcgaggcccccatcacaaaggttataaatata
attaatgcagcccaagaaaacagccctgttacagtagcagaagccttggacagagtttta
gaaattttacggaccacagaactgtactcccctcagctgggcaccaaagacgaagatcct
cacaccagtgatctcgttggaggcctgatgactgatggcctgagaaggttgtcaggaaac
gagtatgtgttcactaagaatgtgcaccagagtcacagtcaccttgcaatgccaataacc
atcaatgatgtccccccgtgtatcgctcaattacttgataatgaggaaagttgggagttc
aacatctttgagttggaagctgttacacataaaaggccattggtttacctgggcttaaag
gtcttttcccggtttggagtatgtgaatttttacgctgttctgaaacgactcttcgggcc
tggctccaagtgattgaagccaactaccactcctccaatgcttaccacaactccacccat
gccgcggatgtcctgcacgccaccgccttcttcctgggaaaggagagagtgaagggaagc
ctggaccagctggatgaggtggcagcgctgattgctgccacagtccatgatgtggaccac
ccaggaagaaccaactctttcctctgcaacgcaggcagtgaacttgctgtgctctacaat
gacacggccgtcttggagagtcaccacacggccctggccttccagctgacagtcaaggac
agcaaatgcaacattttcaagaacattgacaggaaccattatcgaacactgcgccaggct
attattgacatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaattt
gtgaacagcatcaacaagccaatggcagctgagattgagggcagcgactgtgaatgtaac
cctattgggaagaacttccctgagaaccaaatcctgatcaagcgcatgatgattaagtgt
gccgatgtggccaacccatgccgccccctggacctgtgcattgaatgggccgggaggatc
tccgaggagtacttcgcacagactgatgaagagaagagacagggactacctgtggtgatg
ccagtgtttgaccggaatacctgtagcatccccaagtcacaaatttccttcattgactac
ttcataacagacatgttcgatgcttgggatgcctttgcacatctgccagcactgatgcaa
catttggccaataactacaaacactggaagacattagatgacctgaagtgcaaaagtctg
aggcttccatctgacagctaa
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