Plecotus auritus (brown big-eared bat): 308257718
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Entry
308257718 CDS
T11911
Symbol
AC0HY7_024551
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3-like
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pots Plecotus auritus (brown big-eared bat)
Pathway
pots00230
Purine metabolism
pots00670
One carbon pool by folate
pots01100
Metabolic pathways
pots01523
Antifolate resistance
Module
pots_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pots00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
308257718 (AC0HY7_024551)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
308257718 (AC0HY7_024551)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
308257718 (AC0HY7_024551)
Enzymes [BR:
pots01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
308257718 (AC0HY7_024551)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
308257718 (AC0HY7_024551)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
308257718 (AC0HY7_024551)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
AIRS
GARS_C
ATP-grasp
ATP-grasp_4
ATP-grasp_LDMS
DUF498
Dala_Dala_lig_C
CPSase_L_D2
RimK
ATP-grasp_2
Motif
Other DBs
NCBI-GeneID:
308257718
NCBI-ProteinID:
XP_080543958
LinkDB
All DBs
Position
9:complement(<46034503..>46037713)
Genome browser
AA seq
990 aa
AA seq
DB search
MARVLVVGSGGKEHTLAWKLAQTSHIKQVLVAPGNASTVGSEKISNTAISISDHSVLAQF
CKDENIEFVVVGPEAPLAAGIVGDLVAAGVRCFGPTAQAAQLESSKRFAKEFMDRHGIPT
ARWRAFTELKDACSFILSADFPALVVKASRLTTGKGVIMAESREEACRAVQEIMQDKAFG
AAGETIVIEELLEGEEVSCLCFTYGRTVAPKSPAQDHKRLLEGDRGPNTGMGACCPAPQV
SKDLLLKIKNAILQQTVDGMQQEGMPYAGVLYAGVMLTRDGLKVLEFNCCFGDPECQVIL
PLLKSDLYEVIQSTLDGLLCAALPVWLENRAAITVVMASQGYPEDYAKGVEITGAEAQAL
GLEVTKDGKVVTTIRDTLVAALEGAKQGLAAIKFEGAIYRKDIGGRAIAFLQKPRGLMNK
DSGVDIAAGNLLVQKIKPLAKATSRPGCDVDLGGFAGLFDLKAAGFKDPLLVSGTDGVGT
KLKIAQQCNQRGTIGQDLVAMCVNNILAQGAEPLFFLDYFSCGNLDVGTAAAVVADIAEA
CRKAGCALFGGETAEMPDMYSPEYDLAGFAMGAVERDQQLSQLESIAEGDVVIGIASSVL
HSNGFSLVRKIVVKSSLQYSSLAPHGCSDQTLGDLLLTPSRIYSHSLLPVLCSGHVKAFA
HITGGGLLENIPRVLPPRCGVELDARAWRVPTIFSWLQHKGRLSDEEMARTFNCGVRATL
MVSEDLAEQVLRDVRQHQEEAWLVGRVVARPEGSPQVRVGHLLDALWLSRPALQNGSMLS
PFSAPEKARLTVLISGTGSNLQGLIDSTREPSSAAHIVMVVSNKAAAAAGLDQLASAGIP
TRMLNYKLNESHVEFDMAIDQVLEEFSADIVCLAGFMRILSGPFVRKWNGRMLNIHPSLL
PSFKGANTHEQALDGVAVMGRTVHFVAEDVDAGRIILQEAVPVRRGDTVATLSERVKVAE
HRIFPAALQLVASGAVQLGKDGRLCWAQEK
NT seq
2973 nt
NT seq
+upstream
nt +downstream
nt
atggcccgagtgcttgtcgttggcagtgggggcaaagagcacacgctggcctggaaactg
gcgcagacttctcacatcaaacaggtgttggtcgcccccggaaatgcaagcactgtcggc
tctgagaagatttcaaacaccgccatctccatcagcgatcacagtgtcctcgctcagttc
tgcaaagatgagaacattgaattcgtagttgttggaccagaggcacctctggctgctggg
atcgtcggggacctggtggcagcaggcgtgcggtgctttggccccacagcacaagcggct
cagctagagtccagcaaaaggtttgccaaagagttcatggaccgacatggcatccccacc
gcccggtggagagccttcaccgagctcaaggacgcctgcagctttatcctgagtgcagac
ttccctgctctggtcgtgaaggccagccgcctgaccaccgggaagggggtgatcatggca
gagagcagagaagaggcctgcagagccgtgcaggagatcatgcaggataaagcttttgga
gcagctggagaaacgattgtcattgaagaacttcttgaaggagaagaggtttcttgtctg
tgcttcacctatgggaggaccgtggctcccaagtcccccgcgcaggaccacaagcggctg
ctggagggagatcgtggccccaacacggggatgggggcctgctgcccagccccgcaggtc
tctaaggatttgctgctgaagattaaaaatgccatccttcagcagacagtggacggcatg
cagcaggagggcatgccgtacgcaggtgttctctatgcgggtgtgatgctgaccagggat
ggcctgaaggttctggagtttaactgctgtttcggggacccggagtgccaagtgatcctc
ccgcttcttaaaagcgatctttatgaagtgattcagtccaccctggatggcctgctctgt
gcagctctgcctgtttggcttgaaaaccgggcggccatcactgttgtcatggcaagtcag
gggtatcccgaagactacgccaaaggtgtagagataacgggtgccgaggcccaggcttta
gggctggaggtgaccaaagacggcaaagtggtgaccaccatccgggacactctcgtcgca
gcccttgaaggggccaagcaaggactggctgctataaaatttgagggcgccatctacagg
aaggacattggcggccgcgccatagcgttcctccagaagcccaggggcctgatgaacaag
gactcgggggtagacattgcagctggaaatctgctggtccagaaaattaagcctttagcc
aaagccacctccagaccaggctgtgatgtggatcttggaggttttgctggtctttttgat
ttgaaagcagcgggtttcaaagatcctctcctggtcagtggaacagatggtgttggcacg
aaactgaagattgcccagcagtgcaaccaacgtggtaccattggccaagacttggttgca
atgtgtgtaaacaatatcctggcacaaggggcagagccccttttcttcctcgactacttt
tcctgtgggaacctcgatgttggcacagctgcagcagtagtcgctgacatcgctgaagcg
tgcaggaaagctgggtgtgccctcttcggaggggaaacagcagaaatgccggacatgtat
tcccctgagtatgacctggccgggttcgccatgggggccgtggagcgggaccagcaactc
tctcaactggaaagcatcgctgaaggggatgttgttattggaatagcgtcatctgttctc
cacagcaacgggttcagccttgtgaggaagattgtagtgaaatcttcccttcagtactcc
tctctggcaccccacggctgcagcgaccagaccttaggggacttacttctgactccgagc
agaatctacagccactccctattacctgtcttgtgttcgggccatgtcaaggcctttgcc
cacatcaccggtggagggctgctggagaacatcccccgtgtcctccctccaagatgcggg
gtggagttagatgcccgggcctggagggtccccacgatcttctcgtggctgcagcacaaa
ggacgcctctcagacgaggagatggccaggacctttaactgcggggtcagggctaccctc
atggtgtcagaggacctggcagagcaggtgctgagggatgttcggcagcaccaggaggag
gcctggctggtcggcagggtggtggcccgccctgaaggttctccccaagtgagagttggg
cacctgctggacgccctgtggctgagcaggcctgcgctgcagaacggctccatgctcagt
cccttctctgccccggaaaaggccagattgaccgtcctcatctctgggacaggctcgaac
ctgcaggggctgatagacagcacccgggaaccgagcagcgccgcccacatcgtcatggtt
gtctccaacaaggcggccgcggcggctgggctggaccaactggcgagtgcgggcattccc
accaggatgcttaattacaagttaaatgaaagccatgtcgagtttgacatggccattgac
caggttctcgaagagttctctgcggacatcgtctgtctggcagggttcatgaggatcttg
tctggcccctttgtcaggaagtggaatgggagaatgctcaacatccacccgtccctgctg
ccgtccttcaagggcgccaatacccacgaacaagccctggatggtgtcgcagtgatgggg
cgcactgtgcactttgttgctgaagacgtggatgctggacggattattttacaagaagct
gtgccggtgaggaggggcgacactgtggccaccctgtccgagagggtgaaggtcgcggag
cacaggatcttccccgcggccctgcagctggtggccagtggtgccgtgcagctgggcaag
gacggccggctctgctgggcccaggagaagtga
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