Paralichthys olivaceus (Japanese flounder): 109624654
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Entry
109624654 CDS
T06037
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
pov
Paralichthys olivaceus (Japanese flounder)
Brite
KEGG Orthology (KO) [BR:
pov00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pov01001
]
109624654 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pov04131
]
109624654 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pov04147
]
109624654 (lrrk2)
Enzymes [BR:
pov01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109624654 (lrrk2)
Protein kinases [BR:
pov01001
]
Serine/threonine kinases: TKL group
LRRK family
109624654 (lrrk2)
Membrane trafficking [BR:
pov04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
109624654 (lrrk2)
Exosome [BR:
pov04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
109624654 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_14
Arf
AAA_22
Septin
NACHT
LRR_9
AAA_16
LRR_NXF1-5
Beta-prop_EML_2
Viral_helicase1
MMR_HSR1
Ank_2
G-alpha
PduV-EutP
Kdo
nSTAND3
T2SSE
cobW
ATP_bind_1
GTP_EFTU
MDM10
FeoB_N
DUF7079
AAA_7
TniB
SRPRB
NB-ARC
Ank_4
AAA_18
MobB
ABC_tran
Motif
Other DBs
NCBI-GeneID:
109624654
NCBI-ProteinID:
XP_019935053
LinkDB
All DBs
Position
Unknown
AA seq
2549 aa
AA seq
DB search
MVDREELQERLKKLVVRLKTPQEDRQLCTLIQIIQDLLLLAHADHAADLFEDKDVHVPLM
TVLTSYRNSRGVQQVGWSLLCRLIEICPATLDQLIPPLRAANEWEVLGAHQQILKVLCLY
SADCRVTVVGLRALALLLRSDMIALLVLEEEEDVFGLVVQAMKTFPTSEEVQLQGCRALQ
VLLQRVSDDHLVEFVEIQDHFVILAALQMFPDSSELLLQAMKVLLPLARPGSNVEMLMSG
GARCYSVIITAMDTFPEVEELQETACCLFRKFTSESYYNILVLNGVQRVAVRACQTFPDN
ATLQAAALSCLADLTSTIVQNKAVAEQGLEKGEEEENRGKEEVEDMGLGWMEACCMALER
HAAEPAVQEAASWAIHNLLLHGAGVSHSEEDQERRTPVHRQLMVAMLLHSSSPSVFKAAT
SAIAVLITHNSKMRSLLLSSGLHVNLVEMMKRHVTSVEVSISACKLLNLLFQGRIASLDE
LNMAMSQILSTMKVHNFQPEVQLEALQASLVFLCPDRSLREHGVSVADPDMVDVSLKVLK
NQCVVEGAHTLYLEVLNRFISSSNIQRCGLKVLSALADCSGAVDLLCQQGAIDTVLHTLQ
MFPREREIHYWGLTLLSYLVSKKKLSRMIVPILASVVVVSLTQYSGDSEMLLKCFQVALR
MLDACSGAAAELQREDFDRHIFQQLREETPDQSNSPLRRSVCLALSKMWCDSELHYSMLE
KACRDGDTMMAECLIELGANVNRKTKTESLIYQVCERGGPLELVELLISRGAHEQHLRRA
LAVSVKLCDGPTVIQLLGRLGLDLNNSALCLGGFKLGRVDPNWLGPLFAERGRTPGLRYS
NGKGMSLARYIQSLQRSKSISGPSRSMADPCLTSGYISDESDDSIFSCFSMDDSLTFNDD
MESDGSDSLLGALSPKPHDNSTEELKMGSFGRKQRRHRNASAESGQTESEHCDPVQRRYV
RTGSTHRLLGSVENSALTRERERIRLLDLSGNELDSLSCLMDSGFVQEQLGHLLRLDLSH
NSLLEFPSALCQSLNSLTRLDLQGNQLQSLPVELLSLPSLGSLNVSRNCVGPLLTFDPAA
TWPSLRQLNLSFNKITTFPHELGRTMDHLEELFIEGNSITELCTPLYLPEIKLLDVSKNS
VENISPDFLTGCPKLETFNASMNKICSLSHLTSKIMTLKLANNNFTHVSEAILDLPNLRS
VDMRTNHIAVLPGPGYWASSNLRELMFSQNCIAALDLNGPTSKWIRLEKLHLSDNKLSEI
PPQVGLLEGLTSLDVSRNTNLRSFPDEMGKLSRLWDLPLDGLRLQLDLKLIGSKTKDIVR
FLQQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKLKRSQSNSKRSTVGITVRDWVIGE
RDKKKMVMNVWDFSGGEEFSGSHPHFLTSRAIYLVVYNLSKGASQVDALKPWLFNIKAVA
PLSPVILVGTHTDVSDEQQLHDCLTKIRKELLNHQGFPTIKDYHMVSVCEDSDSMAKLRK
AIAGEVTSFKIQGQPVMGQPVPDCYVELERRILLERTRVPPEFPVLRHQELLQLIQESQL
HLEEAEMPHAVHFLSEAGVLLHFDDPALQLQELYFIDPQWLCNIISQKLTFKSCGFWEQP
KGTVLRSVVEKFLMETKCFPKSHLMQFFKLLEKFQIALPFGEDQLLVPSNLSKHRPVIEL
PHSENSEVIVRLYEMPYFPMDCWSRLISRLLEVSSYLLCGRDKVMRPNRIYWRRGVYLSW
GPEAYCLVEAASEEGNPSSFIRITVPSSRKGCALLGQVVDHIDSLLEEWFPGLLNMDMHG
SGEALLKKWALYSFDDRQEWSKILLEDLFPYFDKDFLLVNPEDPRYTLPISQIAPDLVLS
DQSAGTILDSEELDVELSKETQLGNGGFGTVYRGVYKNEEVAVKIFNKHASELYIHRLLR
QELVVLGRLHHPSLVGLLAAGSASPAGSASQVLVMELALRGSLDSLFEHKKSSLNQKLQH
RIALQVADGLRYLHSAMIIYRDLKPHNVLLFNLKTEADVIAKITDYGIAQYCCSMGVRSS
EGTPGFRAPEVARGNVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEGAVQGNL
PDPVNHYGCSPWPGFQVLMKECLRQSPQDRPTSAQVFDRLNSGEMLCLMKELHPPRAFNA
ECLTVSTVGSDCPFSSNTVWLGGGSSTQRVGYISAVDLDTNAVTSQDIDTSPVLCLVTVQ
IPNEACDWLVAGTQSGSLVVISTQDTSAWHHLQSVTDAVTSLYFHVHPCRAQRNNYLLVG
TANGLLTVYEDSVLKKESGQPVKTVCVGNVSTPVMCLSQSVHPLDSRAVWAGCGTTIRSF
AVDYDVSKTIDTRQKLVFQQQRPLGGEACVSRMVVDKYVYLSKAGSSTVEVWDKRSERMV
DSIDCAQIIRHDSGRRGRKCNKADRPSEVAPSWARVKSLLVQSAAALWIGTRGGHLLLLE
LSKHQTLQVIGPRCESIRCIASALIATLNWKNVVLVLGRRHPQDKSLCDEESVLMVWNGT
LPKEARDLNRHCEKREQIAAKMREQLQHH
NT seq
7650 nt
NT seq
+upstream
nt +downstream
nt
atggtggaccgggaggagctgcaggagaggctgaagaaactggtggtgaggctgaagacc
cctcaggaggacaggcagctgtgcaccctgatccagatcatccaggatctgctcctcctg
gcgcacgcagaccacgcagctgacctgtttgaagacaaagatgtccacgtccctctcatg
acagtgctgacgtcctacaggaatagcagaggagtccagcaggtgggctggtcgttgctg
tgtaggctgattgaaatatgtcccgccacgctggaccagctgattccaccgctgcgggca
gccaatgagtgggaggtactgggagcgcaccaacagatccttaaggtgctgtgtctgtac
agcgcagactgcagagtgaccgtggtgggactacgagccctggcgctgctgctccgttca
gatatgattgccctgctggtgctggaggaggaagaggatgtgtttggcctggtggtgcag
gcgatgaagacgtttcctaccagtgaggaagtgcagctccaaggctgcagagctctgcaa
gtcctcctgcagagagtaagtgatgaccacctggtggagtttgtggagatccaggaccac
tttgtgatcttggcggctctacagatgttcccagacagttccgagctgctcctgcaggcc
atgaaagtgctgctcccgctggctcgtcctggcagtaacgtggagatgttgatgtcggga
ggcgctcggtgctacagcgtgatcatcactgccatggacaccttccctgaggtggaggag
ctgcaggagacggcctgctgcctcttcaggaagtttacatcagagagttactacaacatc
ctggtcctgaacggcgtccagagggttgccgtgagagcctgtcagactttccccgacaac
gccacgctgcaagcggccgctctctcctgcctggctgacctcacttcgaccatcgtgcag
aacaaagcggtggccgagcagggtctggagaaaggagaggaggaggagaacaggggtaaa
gaggaggtagaggacatgggcctgggctggatggaggcctgctgtatggctctggagcgc
cacgcagctgagccggcggttcaggaagccgcaagctgggccattcacaatctgttactg
cacggtgctggagtgagccactcagaggaggaccaggaacggaggactcctgttcacaga
cagttaatggtggccatgctgctccactcctcctctcccagtgtgtttaaagctgctacc
agtgccattgccgtgctcattactcacaacagtaaaatgcgttctctgctgctgtccagt
ggcctccatgtcaacctagtagagatgatgaagagacatgtaacctcagtggaggtttcc
atcagcgcctgcaagctgctcaatctgctcttccagggaaggatagccagtctggatgag
ttgaacatggccatgagtcagatcctcagcaccatgaaggtccacaacttccagccggag
gttcagctggaggctctgcaggccagcctggtcttcctctgcccagataggagtctacgg
gagcacggcgtctcggtcgcagaccccgacatggtcgacgtgtcgctgaaagtcctgaaa
aaccagtgtgtggtggaaggagctcacacgctctacctggaggttctgaacaggttcatc
agcagctcgaacatccagaggtgcggtttgaaggtgctgtctgcactggctgactgctct
ggtgcagtggacttgctttgccagcagggggccatagacacggtgctacatacactacag
atgttcccacgggaacgagaaatacactactggggtctgaccctgctcagctacctcgta
tccaagaagaagctgtcgaggatgatcgtgcccatcctggcctctgttgtggtcgtctca
ctcacccagtatagcggagactccgagatgctcctgaagtgttttcaggtggcgttgagg
atgctggatgcttgttcgggagcggctgctgagctgcagagagaggacttcgacaggcac
atcttccagcagctcagagaggagacccccgaccaaagcaacagccctctgcggaggtca
gtgtgcctggccctgtcgaagatgtggtgcgactcggaactacactacagcatgctagaa
aaggcctgcagggacggagacacgatgatggccgagtgtctgatcgagctgggcgccaac
gtcaaccggaagacgaagacagagtctctcatctaccaggtgtgtgagagaggcggacct
ctcgagctggtggagctcctgatcagccgaggtgcacacgagcagcacctccgcagggct
ctggctgtgagtgtgaagctgtgtgatgggcccacagtcattcagctgctgggccgtctg
ggtctggacctcaacaacagtgccctgtgcctggggggcttcaaactgggtcgcgtggac
cctaactggctcggccccttgtttgcagaaagaggaagaactccaggtctccgctatagc
aacggtaaaggcatgagtttggccaggtacattcaatctctccagaggtccaagagcatc
agtggtccttccaggtcaatggccgacccctgtctgacctctggctatatttctgacgag
agtgacgactccatcttcagctgtttctccatggacgacagcctgactttcaacgacgac
atggaaagtgacgggagtgattcgctgttgggggctctgtctccaaaaccacatgataat
tcaacagaggagctgaagatggggtccttcggtagaaagcagaggcgtcacagaaatgcc
agtgcagagagtggtcagactgagagcgaacactgtgaccctgtacagaggcgatatgtg
aggactggctccacccacagattgctggggtctgtggagaactctgctctgaccagagag
agggagaggatccgcctgctcgacctgtctgggaatgagttggactctctgtcttgtctg
atggacagcggctttgtgcaggagcagctggggcatctcctccgcctcgacctgagccac
aacagtctgctagagtttccttcagctctttgccagagtctgaacagtttgactcgactg
gacctgcagggtaaccagctccagtcgctgccggtggagctgctgtctctgccgtcactt
ggctcactgaacgtctctcgtaactgtgtgggtccccttctgacctttgaccctgctgcc
acctggccgtcactgcggcagctgaacctgtctttcaacaaaatcaccacattccctcac
gagctgggccgcaccatggatcacctggaggagctgtttatagaaggaaacagtataact
gagctgtgcacgcccctgtacctgccggagatcaagctgctggatgtgagcaagaacagt
gtggagaatatttctccagactttctgacgggctgccccaagctggaaactttcaatgcc
tccatgaacaaaatctgttccctgtcacacctgacgtccaagatcatgacactaaaacta
gcaaacaacaacttcactcatgtttctgaggctatactcgatcttccaaacttaaggtct
gtggacatgagaaccaaccacatcgccgttcttcccggcccaggatactgggcgtccagc
aatctcagagagctgatgttcagtcagaactgtatcgcagctctggatctaaacgggcca
acctccaaatggatccgcctggagaaactccacctgagtgacaacaagctcagtgagatt
cctccacaggttggcctcctggaaggcctgacctccctggacgtgagccgtaacactaac
ctgcggtcgttccctgatgagatggggaaactaagcagactgtgggacctgccgctggat
ggtcttcggctccagctggatctcaaactcattggcagcaaaaccaaagacatagtcagg
ttcctgcagcagcggctgaagaaggcagtgccatactatcggatgaagctcatcgtggtg
gggaatgctggcagtgggaagaccaccctgattcagcagttaatgaagctgaagcgctcc
cagtcgaactcaaaaaggtccaccgttggtatcacagtcagggactgggtcatcggtgaa
cgagacaaaaagaagatggtgatgaatgtctgggacttttcaggtggagaggagttcagt
ggctctcaccctcacttcctgacctccagagctatttacctggtggtttacaacctcagc
aaaggagccagtcaggtggacgccctcaaaccctggctcttcaacatcaaagcggtggcc
ccgctctccccggtcatcctggtggggacacacacagatgtgagtgacgagcagcagctt
catgactgcctgaccaagatcagaaaggagttgctcaaccaccagggtttccccaccatc
aaggattatcatatggtctccgtctgcgaggactcggactccatggccaaactccgaaag
gccatcgccggagaagtcacgagctttaagatccagggccagcctgtgatgggccagcca
gttccagactgctatgtggagctggaacgccgcattctcctggagaggaccagggttccc
ccggagttccccgtcctcaggcaccaggagctgctgcagctcatccaggagagtcagctg
cacctggaggaagctgaaatgccccacgccgtccacttcttgagtgaagccggggtttta
ctgcactttgatgatccagcacttcaactccaagagctttactttatcgacccacagtgg
ctctgcaacatcatctcccagaaactgacatttaagagctgtggcttctgggagcagcct
aaaggaactgttctgcgctcggtggtggaaaagttcctgatggagaccaaatgtttcccc
aagagccacctgatgcagttcttcaaactgctggagaagttccagatcgcgctgccgttc
ggagaggaccagctgctggttcccagcaatttgtccaaacacaggccggtcatagagctg
cctcacagtgagaactcagaggtcattgtgcgtctttacgagatgccatacttccccatg
gattgctggtctcgactcatcagccgcctactggaggtttcttcttacttgctctgtgga
agagataaagttatgcgacccaaccggatctactggaggagaggagtttacctgagctgg
ggccctgaggcgtactgtctggtggaagctgcctcagaggagggaaatccctccagcttc
atcagaataactgtgccctcttcacgtaaaggctgtgcgttgctgggtcaggtggtggat
cacatcgactccctgctggaggaatggtttcctggcctgctgaacatggacatgcacggc
agcggtgaggctctgctgaagaagtgggctctgtacagctttgatgacagacaggagtgg
agcaagatcctgctggaggacctctttccttactttgacaaggattttttgctggtgaat
ccagaggacccgcggtacacactgcccatctctcagatcgcccctgacttagtacttagt
gatcagtctgcaggaaccattctagacagtgaagagctggatgtggaattatcgaaggaa
acccaacttgggaacggtggctttggaacagtctatcgaggtgtctacaaaaatgaggaa
gtagcggtgaagatattcaacaagcatgcgtctgagctctacatccacaggctcctcaga
caggaattggtggtgttgggtcgcctccatcaccccagcttggtcggcctgctggcagct
ggttcagcctctccagctggttcggcctctcaggtcctggtgatggagttggctctgcgt
ggctcactggactctctctttgaacataagaagagcagcctcaaccaaaagctccagcac
aggatcgccctgcaggtggctgatggactcaggtaccttcactcagccatgatcatctat
cgggatctgaagccccacaacgtgcttctattcaacctgaagaccgaggccgacgtcatc
gccaagatcacagactacggcatcgcccagtactgctgcagtatgggagtgaggagctca
gaaggcactccaggttttcgagcaccggaggtcgcccggggtaacgtgatctataaccag
caggctgatgtgttctcattcggtctgctgctctacgacctcctgacctgtggcgagcgc
atctctgatggaatgaagttccccagtgagttcgatgaaggggcagtgcaggggaatcta
ccagatccagtaaaccactacggctgctcaccgtggccgggcttccaagtgctgatgaag
gaatgtctgaggcaaagtccacaggatcgacccacttccgctcaggtgttcgataggctg
aattcaggggagatgctgtgtctgatgaaggagctgcatcccccccgtgctttcaacgct
gagtgcctcacggtgagcactgtcggcagtgactgtcctttcagcagcaacacagtctgg
ctgggagggggcagcagcacgcagagggtgggctacatctcagctgtggacctggacacc
aacgcagtcacttctcaggacatcgacaccagtcccgtcctttgtcttgttacagtgcaa
atcccaaacgaggcctgcgattggctggtggccggcacccagtccggctctttggtggtc
atcagcactcaggacacgtcagcttggcaccacctgcagagtgtcacagacgctgtcacc
tcgctctacttccatgtgcacccctgtcgagcccaaagaaataattatctgctggtgggg
acggccaacggacttctcacagtttatgaagactctgtgctcaagaaggaaagtgggcaa
cccgtgaaaactgtctgtgtggggaacgttagcacgcctgtcatgtgtctgagccagtcg
gtgcatcccctggacagcagagcggtgtgggctggctgcggcaccacgatccgctccttc
gcggtcgactacgatgtctccaagaccatagacacgcgacagaagcttgtgttccagcag
cagcggccattggggggcgaggcttgtgtatcaagaatggttgtggataaatacgtttac
ctgagcaaagccgggtcatcaacagttgaggtttgggacaagaggagtgagaggatggtg
gactccatcgactgtgctcagatcatcagacatgactctggccgcagaggcaggaagtgc
aataaagcagaccggccctctgaggtagctccctcctgggccagagtgaagtccctgctg
gtgcagagcgctgcagctctctggatcggcactagagggggccacctgctgctgctggag
ctctccaaacaccagacgctgcaggtcatcggccctcgctgcgagtccatccgctgcatc
gcctctgcactcatagcaacactgaactggaagaatgtggtgctagttttgggcagaaga
cacccacaagataaaagtctgtgtgacgaggagtcggtgctgatggtgtggaacggcacg
ctgccgaaggaggccagagacttgaacagacactgcgagaagagagagcagatcgcagcc
aaaatgagagagcagcttcagcaccactga
DBGET
integrated database retrieval system
