Paralichthys olivaceus (Japanese flounder): 109634294
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Entry
109634294 CDS
T06037
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pov
Paralichthys olivaceus (Japanese flounder)
Pathway
pov04217
Necroptosis
pov04620
Toll-like receptor signaling pathway
pov04621
NOD-like receptor signaling pathway
pov05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
pov00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109634294 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
109634294 (tyk2)
04621 NOD-like receptor signaling pathway
109634294 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
109634294 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pov01001
]
109634294 (tyk2)
Enzymes [BR:
pov01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109634294 (tyk2)
Protein kinases [BR:
pov01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109634294 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
SH2
Kdo
Kinase-like
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
109634294
NCBI-ProteinID:
XP_019950262
LinkDB
All DBs
Position
Unknown
AA seq
1161 aa
AA seq
DB search
MSRRWWSRRSKSGQFPGQAEPPQGKGVHVFLLWTKEGERYLSHTSGEVTAEELCISAAEA
VGITPLCHVLFALYNPLSSCWYSPNHIFNPEEDSSLVLHYSMRFYFHNWHGLYEKEPVVC
RYRLRSGSNQGNSLLLDFTSLEYLFSQAKYEFVNEVMQMEDIQSEEELSRFKNESLGMAV
LHLSHQAMQTGCTLQEVAEKVCFLRCIPKSFSKQISKDNFLTKIRINRVFADFVQTFQQH
TVDEGRLGTQDIMYKYISTLEHLVPRFGTETFPVSHLELREDGDGGSSYHAQGDSKDNFT
APITHEIMVSGTKGIHWRKVSVQKAQVNGYFRSDYLSMKKSKNQSSQSDATTPNTLSFFS
DFPEITHISLSGANVCISTQDNRCMVVQMNSSQEARSFISLLDGYYRLTADAHHYLCHEV
APPRVVLSEANGLHGPMHDDFVLLKLKKEAAEEGAFLVRWSALDYRRLILAVLNKDKDGS
RLSHKQFRIQHKESMFCLEGWDQEFSSVKELTESLKSFMLKSGPDSFTVKKCCLPRQAEL
SNLLVMRKGVDRVKPDPLSLNLTQLRFHQIKDRELVQEQHLGRGTRTNIYSGHLVVQGRG
GDNDDDEFNNNANDRKGIRVVLKILDQSHKDIALAFFETASLMSQVSHSHLVFVHGVSVK
GSENIMVEDFVEFGPLDVFLRKEKASVTPQWKFIVAKQLASALNYLESKRLVHGNVCAKN
ILVARKGLEPGTTPFIKLSDPGIALSVLSRDERLERIPWIAPECVESGALIGNVDQWSFG
VTLLEICNNGDLPMSSSALSEKERFYQQKGRLAEPSSQELASFISMCLTYEPLERPTFLT
VLRKLTEIMTKNPDISPSETLTDIDPSIFHKRYLKEIRELGSGHFGKVILYLYDPANDGT
GECVAVKSLKQENGHAPDGWMKEIEILKSLYHSNIVKYKGCCTELGGQVVQLIMEYLPQG
SLRDYLIKRKLGVPQYLMFAQQICQGMEYLHTKRYIHRDLAARNVLVENDTLVKIGDFGL
TKYIPEGEIYYRVREDGDSPVFWYAIECLKENKFSFSSDIWSFGVTLYEILTGCDPNQSP
PTKYFEMMAAPKEPMTMMVLIKLLEKSLRLPCPKECPHVVKKLMEECWAAKPTLRPSFTS
LIERLKTIRQTYDFSLFQNCS
NT seq
3486 nt
NT seq
+upstream
nt +downstream
nt
atgtctaggaggtggtggtccaggcggtccaagtcaggccagtttccagggcaggctgag
cctcctcagggtaaaggcgttcatgtattcctcctctggaccaaagagggggagagatat
ttgtctcacacgagtggagaggtcacagcggaggagctgtgcatctcagccgctgaggct
gtagggataacacctctgtgccatgtgttgtttgctctgtacaatccactctcaagctgc
tggtacagtccaaaccacatcttcaatccagaggaagactccagtctagtacttcattac
agtatgaggttttactttcacaattggcatggactatatgagaaagagccagttgtgtgc
cgctatcgtctccgatctgggagcaaccaggggaattcacttctgcttgacttcacatcc
ctggagtatttattctctcaggctaaatatgaatttgtgaatgaagtgatgcagatggaa
gacatccagtcggaagaggagctaagtcgcttcaaaaatgagagcttggggatggctgtg
cttcacctctcgcaccaggcgatgcaaacaggctgcacgttacaagaagtcgcagagaaa
gtctgcttcctacgctgcatcccaaagtctttctccaaacaaatttccaaagacaacttc
ctgactaaaatcaggatcaatcgggtgtttgcagactttgtgcagaccttccagcaacac
actgtggacgaggggcggctgggcacacaggacatcatgtacaagtacatctctactctt
gaacacctggtgccacggtttggcacagagaccttccccgtgtcccacctggagctgagg
gaggacggggacggaggcagctcttaccatgcacagggcgattcaaaagacaacttcaca
gctcccatcacgcatgaaataatggtgtccggcaccaaggggattcactggaggaaggtg
tccgttcagaaggcacaggtaaatggttacttccggagtgattacttgagcatgaagaaa
tccaaaaaccagtccagccagtcagatgcaaccactcccaacactctgagcttcttctcc
gatttccctgaaataacacacatctccctcagtggcgctaatgtgtgcattagcactcag
gacaatcggtgcatggtggttcagatgaactccagccaggaggcgcgttccttcatctca
ctcctggatggatactaccggctgactgcagacgcccaccactatctttgtcatgaagtg
gctcccccaagggtagtgctgagtgaagcaaatggactgcatggacctatgcatgatgat
tttgtgctgctgaagctgaagaaagaggcagcagaagagggagctttccttgtacgttgg
agtgctctggactatcgccgcctcattctggctgtgctaaacaaagataaagacggatcg
agactgagccacaagcagtttcggatccagcacaaggagtcgatgttctgtctggagggc
tgggaccaagagttctccagtgtgaaggagctcacagagagcctcaagtccttcatgctc
aagtctggaccagacagcttcactgtgaagaaatgctgtttgccaagacaagcagaactg
tccaaccttctggtgatgaggaaaggtgtcgaccgggtaaaacctgaccccttgtccctg
aacttgacccagcttcgcttccaccagatcaaggacagagagcttgtacaggaacaacat
ctgggccgcggtaccagaactaacatctactcaggccatcttgtggtgcagggaagaggt
ggcgacaacgatgacgacgagttcaataacaacgccaatgaccgcaaagggatcagagtg
gttctcaagattctagaccaaagccataaagatattgcactagcattttttgaaaccgcc
agtctcatgagccaggtatcccacagtcacctggtgttcgtgcatggcgtgtctgtcaaa
ggatctgaaaacatcatggtggaagattttgtggagtttgggcccttggatgttttcctt
cgcaaagaaaaggcatcagtgaccccgcagtggaaatttattgttgccaaacaacttgca
agtgctctcaactatcttgaaagcaaacggctggttcatggaaatgtttgtgccaagaac
attctggtggcacggaaaggtctggagccgggtactacacctttcatcaagctgagcgat
ccaggaattgccctgagtgtcctctcacgggatgagcgtcttgagcgtatcccatggatt
gcccctgagtgtgtcgaaagtggtgccctcatcggcaatgtggaccagtggagctttggt
gtcactctgctcgaaatctgcaacaacggcgatcttcccatgagtagcagtgcattgtcc
gagaaagagcgcttctatcagcaaaagggccgcttagctgaaccatcctcccaggaactt
gccagcttcatcagcatgtgtctgacctacgagcctttggagaggcctacgttcctcact
gtgcttagaaagctcacagaaatcatgaccaaaaatcctgatatatctcccagtgaaact
ctcactgacatagaccctagcattttccataaacgctacctgaaggagatacgtgaatta
gggagtggtcactttggaaaggttattctgtacctgtacgacccagccaatgacgggact
ggggagtgtgtggcggtgaagtccttgaaacaagagaatgggcatgcgcctgatggctgg
atgaaggagatagagattctgaagtctctttatcacagcaacattgtcaagtacaagggc
tgttgtactgaactgggaggacaagtggtgcagctaataatggagtaccttcctcagggg
agtctgcgagactaccttatcaaacgtaaactgggtgtgccacaataccttatgtttgct
cagcagatctgtcagggaatggagtacctacacacaaagcgatacatccatcgagaccta
gctgcccgtaatgttttagtggaaaatgacactttggtgaagattggagattttggtctg
acaaaatacatccctgaaggcgaaatatactaccgtgtccgggaggatggggacagtcca
gtgttctggtatgccattgagtgcctgaaggagaacaaattttccttttcatccgacatt
tggtcctttggtgttacactgtatgagatccttaccggctgtgacccaaatcaaagccct
ccaacaaagtatttcgaaatgatggcggcacccaaagaaccgatgactatgatggtgctc
ataaaactgttggagaaatccctgcgattgccttgtcccaaagagtgtccacatgtggtg
aaaaaattgatggaagagtgttgggctgcgaagcccacactacggccgtcattcacatcc
ctcattgaaaggttgaagactattcgccaaacatatgacttttctctgtttcagaattgc
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