KEGG   Paralichthys olivaceus (Japanese flounder): 109639237
Entry
109639237         CDS       T06037                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
pov  Paralichthys olivaceus (Japanese flounder)
Pathway
pov00562  Inositol phosphate metabolism
pov01100  Metabolic pathways
pov04012  ErbB signaling pathway
pov04068  FoxO signaling pathway
pov04070  Phosphatidylinositol signaling system
pov04081  Hormone signaling
pov04140  Autophagy - animal
pov04150  mTOR signaling pathway
pov04210  Apoptosis
pov04218  Cellular senescence
pov04370  VEGF signaling pathway
pov04510  Focal adhesion
pov04620  Toll-like receptor signaling pathway
pov04625  C-type lectin receptor signaling pathway
pov04810  Regulation of actin cytoskeleton
pov04910  Insulin signaling pathway
pov04914  Progesterone-mediated oocyte maturation
pov05100  Bacterial invasion of epithelial cells
pov05132  Salmonella infection
pov05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:pov00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    109639237
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    109639237
   04370 VEGF signaling pathway
    109639237
   04068 FoxO signaling pathway
    109639237
   04070 Phosphatidylinositol signaling system
    109639237
   04150 mTOR signaling pathway
    109639237
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109639237
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109639237
  09143 Cell growth and death
   04210 Apoptosis
    109639237
   04218 Cellular senescence
    109639237
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109639237
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109639237
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109639237
   04625 C-type lectin receptor signaling pathway
    109639237
  09152 Endocrine system
   04910 Insulin signaling pathway
    109639237
   04914 Progesterone-mediated oocyte maturation
    109639237
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    109639237
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109639237
   05100 Bacterial invasion of epithelial cells
    109639237
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pov04131]
    109639237
Enzymes [BR:pov01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     109639237
Membrane trafficking [BR:pov04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    109639237
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 Colicin-DNase ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 109639237
NCBI-ProteinID: XP_019958166
LinkDB
Position
Unknown
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKDAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYTQLPMD
NFTMPSYARRISTATPYMNGETATKALWTISGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIRPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccaggccctcctcaggagaactatgggggatgcacttgatgccccccagcatc
ctagtggactgccttctgccaaatggcatgattcttacattggagtgccttcgggaggcc
acgctgatcacagtcaagcatgagcttttcaaagaggccaggaagtatcctctgtaccat
ctgctgcaggaggagagctcctacatctttgtcagtgtcacccaggaggcagagcgggag
gagttttacgatgagaccaggaggttgtgtgatctcagactcttccaggccttcctcaaa
gttattgagccagtgggcaacagagaagagaaaattctaaaccgagagataggttttgct
attggaatgcctatatgtgagtttgatttggtgaaagatccagaggtgcaggacttcaga
agaaacattttaaatgtttgcaaagatgctgtggacctcagagacagtaacggaccccac
agtagagctttatatgtgtaccctcccaatgtagaatcctcagtagaacttccccggcac
atctataacaaactagataaaggtcaaatcattgttgtcatttgggttattgtgtcaccc
agcaatgacaaacagaagtataccctcaagatcaaccatgactatgtgccggaacaggtg
attgcggaagccatccgtaagaagacgcgcagcatgctgctctcccaggagcagttaaag
atgtgtgtgcaggagtatcagggaaaatacatcctcaaagtgtgcggctgtgacgagtac
ttactggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgcttgga
cggatgcccaacctgatgctaatggcaaaagacagcctgtatacccagttgcccatggac
aacttcacaatgccgtcgtatgcaaggcgaatatccacagcaacgccctacatgaatggg
gaaacggccaccaaggctctgtggacaatcagtgggacactgaggatcaggatactgtgc
gccacttacgtcaatgtcaacatcagagacatcgacaagatctatgtaaggactgggatc
taccacggtggagagcagctgtgtgacaatgtcaacacacagcgcgtgccctgttcgaac
cccaggtggaatgagtggctgaactacgacatgtacattccagacatcccccgtgccgcc
cgactctgcctctccatctgctctgtgaaagggaggaagggagccaaagaggagcactgt
cctcttgcctggggcaacatcaacctgtttgactacacccacacactagtagcagggaag
atggctctcaacctatggcctgtcccacatggcctagaagacctgctcaatcctatcggc
gtcacaggctctaaccccaacaaggaaaccccttgtcttgagctagagttcgaccacttc
agttgccctgtcaagttccctgacatgaccaccattgaggaccatgcaaactggaatatc
tccagagagcttggcttcaattactgccacactggtttgagtaacagactggcgcgtgac
aaccccctgactgacactgacaacgagcagctgcggcaggtgtgcaacagagacccgctg
tctgaaatcacagagcaggagaaagactttctgtggaggcacagacaagactgtgtcaac
atgccagagatccttcccaagatccttttggctgtgaaatggaactccagagatgaggtt
gcacagatgtattgccttctgaaggactggcctgctatcaggccagaacaagccatggag
ttgctagattgcaacttccccgatcctatgatcagagattttgccgtgaagtgccttgaa
aaatatctaacagatgacaaactttctcagtacctcattcaactagttcaggttctgaag
tatgagcagtaccttgataacccacttgcacgcttcttgctgaaaagggcattaacaaat
cagaggataggacatttcttcttctggcatttaaagtcagagatgcacaacaagacagtg
agccagcggtttggcctgctgcttgagtcatactgccgggcgtgtggcatgtatctaaag
cacctgagcagacaggtggaggccatggagaaactcatcaatctcaccgacctcctcaaa
caggagaaaaaagatgaggcacagaaggttcaaatgaagtttctggtggagcagatgaga
aggccggactacatggatgcactgcaaagcttcacctccccactgaatccagcacatcag
ctgggaaacctccgcctcgaggaatgcaggatgatgtcatcagccaagcgaccgctgtgg
ctcaactgggaaaacccagatatgatgtcagagctgcttttccagaacaacgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcagaatgctgccgtacggctgcctgtca
atcggcgactgtgtggggttgatcgaggtggtgaggagctcgcacaccatcatgcagatc
cagtgtaaaggaggcctaaagggggcgctgcagttcaacagccacacactgcaccagtgg
ctcaaggacaagaacaagggagagatgtacgaccaggccatagatctgttcacacgatca
tgtgcaggctactgtgtagccacatttatcctgggcataggagacagacacaatagcaac
atcatggtcaaagatgatggacagctgtttcacatagactttggccatttcctcgaccac
aaaaagaagaagtttgggtacaagagggagcgtgtgccttttgtgcttacacaggacttc
ttaatcgttattagcaaaggaactcaagagtgtaccaaaacaagggagttcgaaaggttc
caggaaatgtgttacaaagcgtacctggcgatccgacaacacgccaacctcttcatcaac
ctcttctctatgatgctgggctctgggatgcctgagctgcagtcattcgatgacatcgcc
tacatcaggaagaccctggccctggacaagtcggagcaggaagccctggactacttcatg
aagcagatgaacgacgctcaccatggcggctggactaccaagatggactggatctttcac
acgatccgccagcatgccatgaactaa

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