Komagataella phaffii: PAS_chr1-4_0243
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Entry
PAS_chr1-4_0243 CDS
T01092
Name
(RefSeq) Threonine deaminase, catalyzes the first step in isoleucine biosynthesis
KO
K01754
threonine dehydratase [EC:
4.3.1.19
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00260
Glycine, serine and threonine metabolism
ppa00290
Valine, leucine and isoleucine biosynthesis
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01200
Carbon metabolism
ppa01230
Biosynthesis of amino acids
Module
ppa_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
PAS_chr1-4_0243
00290 Valine, leucine and isoleucine biosynthesis
PAS_chr1-4_0243
Enzymes [BR:
ppa01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.19 threonine ammonia-lyase
PAS_chr1-4_0243
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Motif
Pfam:
PALP
Thr_dehydrat_C
UBAP-1_UBA2
Motif
Other DBs
NCBI-GeneID:
8196917
NCBI-ProteinID:
XP_002490359
UniProt:
C4QXV5
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Position
1:1843266..1844933
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AA seq
555 aa
AA seq
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MLSAPRLLTTATGASFVLPLASMLPRVRRSHTKYADLRQADRLPNGHPDYVKLILTSRVY
DVTDESPITHAVNLSQKTNSNVVLKREDLLPVFSFKLRGAYNMIAQLSPEKRSKGVVGCS
AGNHAQGIAFSAKKLGIPATIVMPTATPSIKYQSVARMGARVVLHGADFDAAKKECARIA
QEEGLIDIPPFDHPYVIAGQGTIAMELLRQLNIDKVNAIFVPVGGGGLLAGVASYLKRLA
PHVRIVGVETFDADALYQSLKAKKRVELSSVGPFADGTAVKILGEETFEILKDTVDEVVR
VDTDEICAAIKDVFEDSRTIVEPSGAMSVAGMKRYIANHPEVNHSSATYVPILSGANINF
DRLRFVAERAVLGEGKEVFMSIQIPDVPGTFRKLQSIIHPRQVTEFAYRFNNAHDGLANI
YTSFSVIDRSKEVAQLMSEFKAAGFEALDISKNEIAKLHGRYLVGGVADLPDERLFSFEF
PERPGALTKFLDGIASNWNLTLFHYRNHGHDVGKVLAGISVPSTDEEAFQQFLSNLHYDY
KEETDNVVYRKFLRR
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgttaagtgctccgcgtttgcttacaacagcaactggagcctcttttgttttgcccttg
gcttcaatgttgccaagggtccgtcgctctcacacgaagtacgccgacttgaggcaggcc
gatcgtcttccgaatggacatccagattatgtcaaactcattcttacaagcagagtctat
gatgttacagacgaaagtcctatcacacacgccgttaacctttcacagaaaaccaatagt
aacgttgttttgaaaagagaagacctccttccagtattctcgttcaagctacgtggagct
tacaacatgatcgcccaactgtcgccagagaagcgtagtaaaggtgttgtgggttgctct
gcaggcaaccatgctcagggaattgcatttagcgccaaaaagctgggaatacctgccact
attgtgatgccaactgccactcctagtatcaagtatcagtcagtggcccgcatgggagcg
cgagtggtgcttcatggtgcagattttgatgcagctaagaaggaatgtgcacgtattgcc
caagaggaagggctcattgatatccccccatttgaccatccttatgtgattgctggtcag
ggaactattgccatggaacttttgagacagttgaatattgataaggttaatgctattttt
gttcctgttggaggtggtggtctgcttgcgggtgtagcgtcctacttgaaaagattagca
cctcatgttcgtatagttggcgttgagacttttgatgcagatgcactataccagagttta
aaagcaaagaaacgagttgagctttcctcagttggtccttttgccgatggtaccgcagtg
aagattcttggagaagaaacttttgaaatattgaaggatacagtcgatgaggttgttcgt
gttgatactgatgagatctgtgcagccatcaaggacgtctttgaagacagtaggactatt
gtagagccttctggagctatgtcggttgctggtatgaaaagatatatcgctaatcatcca
gaagtgaaccacagctctgctacttacgttcctattttatccggtgccaatattaatttt
gaccgtctgagatttgttgctgaacgtgccgtgttaggtgaaggaaaagaagtgttcatg
tcaattcaaattccagatgttccaggcactttccgtaaattgcaatcgatcattcatcca
aggcaagttaccgagtttgcttaccgatttaataatgctcacgacggccttgctaacatt
tatacctccttcagtgtgattgatcgttccaaggaggtagcccaactaatgagtgaattt
aaagctgctggatttgaggctttggacatcagtaagaacgaaattgccaagctacacgga
agatacctggtaggaggagttgctgatctaccagatgagaggttattctcattcgagttc
ccagaacgtcctggagctttgacgaaattcttggacggaattgcttcaaattggaacctg
actttgttccactaccgtaaccatggccacgacgttggcaaggtattagctggtatatcg
gtaccttcaacagatgaagaagcattccaacagtttctttccaacctacactatgactac
aaagaagaaactgataatgtcgtttaccgcaagttcttgagacgatga
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