Komagataella phaffii: PAS_chr2-2_0294
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Entry
PAS_chr2-2_0294 CDS
T01092
Name
(RefSeq) E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00010
Glycolysis / Gluconeogenesis
ppa00020
Citrate cycle (TCA cycle)
ppa00620
Pyruvate metabolism
ppa00785
Lipoic acid metabolism
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01200
Carbon metabolism
ppa01210
2-Oxocarboxylic acid metabolism
Module
ppa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PAS_chr2-2_0294
00020 Citrate cycle (TCA cycle)
PAS_chr2-2_0294
00620 Pyruvate metabolism
PAS_chr2-2_0294
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PAS_chr2-2_0294
Enzymes [BR:
ppa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PAS_chr2-2_0294
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
8198194
NCBI-ProteinID:
XP_002491894
UniProt:
C4R290
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Position
2:complement(1837216..1838406)
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AA seq
396 aa
AA seq
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MLKFLSPQSRIAARVANARYMASASPSTVSIDLPASSFETYELEQGPELQFETEKETLLQ
MYKQMVIVRRMEMASDALYKAKKIRGFCHLSVGQEAVAVGIESAITKKDTVITSYRCHGF
TYLRGASVKEVQGELMGKRCGVSYGKGGSMHMFTTGFYGGNGIVGAQVPVGAGLAFAHQY
RNEKNCTFALYGDGASNQGQVFESFNMAKLWDLPVIFACENNKYGMGTSASRSSAMTEYY
KRGQFIPGLKVNGMDVLACYQASKFAKDWTVSGNGPLVMEYETYRYGGHSMSDPGTTYRT
REEVQNMRSRNDPIAGLKMHLIELGISTEEELKAYDKEARKYVDKQTKEAELAPPPEAKM
DILFEDVYVKGSEPPVLRGRINEDSWSFEKNGFANR
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atgctcaagtttctcagccctcaatctagaattgctgcaagagtggccaatgccagatat
atggcttctgcaagcccatcgactgtttccattgacctcccagcctcttctttcgagact
tatgagttagagcaaggtccagagcttcagtttgaaacggagaaggagactctgctgcaa
atgtataagcaaatggtgattgtcagacgtatggaaatggcttcagatgccctctacaag
gctaaaaagattagaggtttctgccacttgtctgtaggccaagaagccgtggctgtagga
attgagagtgctataactaagaaggacactgttattacatcctatagatgtcacggtttc
acatatttaagaggtgcctctgtcaaggaagtccagggtgaattgatgggtaagagatgt
ggtgtgtcttacggtaaaggtggttcgatgcatatgttcactactggattctacggtgga
aacggaattgttggtgctcaagttccagttggtgctggtctggcctttgcacatcagtac
aggaatgagaagaactgtacatttgccctgtacggggatggtgcttctaaccaaggtcaa
gtattcgagtcctttaatatggccaagttgtgggatttgcctgtgatttttgcctgtgaa
aacaacaagtatggtatgggaacttctgcttctagatcatctgctatgactgagtactac
aagagagggcaatttatccccggtttgaaagtgaatggtatggatgttcttgcttgttac
caagcttctaagtttgccaaggactggactgtctcgggaaatggtcctctagtaatggag
tacgagacctacaggtatggtggacactctatgtccgacccaggaaccacttacagaaca
cgtgaagaagtgcagaacatgagatccagaaatgacccaattgcaggcttgaagatgcac
ttaattgagcttggaatatctacagaggaggaactcaaggcctatgacaaggaggctaga
aagtatgttgacaagcaaaccaaagaagctgaactcgctcctccccctgaagccaaaatg
gatattttatttgaagatgtttatgtcaagggttccgaaccccccgtcctgagaggaaga
ataaatgaggattcttggtccttcgagaagaacggcttcgctaatcgttag
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