KEGG   Panthera pardus (leopard): 109245111
Entry
109245111         CDS       T06062                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad03420  Nucleotide excision repair
ppad04115  p53 signaling pathway
ppad04120  Ubiquitin mediated proteolysis
ppad05161  Hepatitis B
ppad05169  Epstein-Barr virus infection
ppad05200  Pathways in cancer
ppad05202  Transcriptional misregulation in cancer
ppad05210  Colorectal cancer
ppad05212  Pancreatic cancer
ppad05213  Endometrial cancer
ppad05214  Glioma
ppad05216  Thyroid cancer
ppad05217  Basal cell carcinoma
ppad05218  Melanoma
ppad05220  Chronic myeloid leukemia
ppad05222  Small cell lung cancer
ppad05223  Non-small cell lung cancer
ppad05224  Breast cancer
ppad05225  Hepatocellular carcinoma
ppad05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    109245111 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    109245111 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    109245111 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109245111 (DDB2)
   05202 Transcriptional misregulation in cancer
    109245111 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109245111 (DDB2)
   05212 Pancreatic cancer
    109245111 (DDB2)
   05225 Hepatocellular carcinoma
    109245111 (DDB2)
   05226 Gastric cancer
    109245111 (DDB2)
   05214 Glioma
    109245111 (DDB2)
   05216 Thyroid cancer
    109245111 (DDB2)
   05220 Chronic myeloid leukemia
    109245111 (DDB2)
   05217 Basal cell carcinoma
    109245111 (DDB2)
   05218 Melanoma
    109245111 (DDB2)
   05213 Endometrial cancer
    109245111 (DDB2)
   05224 Breast cancer
    109245111 (DDB2)
   05222 Small cell lung cancer
    109245111 (DDB2)
   05223 Non-small cell lung cancer
    109245111 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    109245111 (DDB2)
   05169 Epstein-Barr virus infection
    109245111 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ppad04121]
    109245111 (DDB2)
   03400 DNA repair and recombination proteins [BR:ppad03400]
    109245111 (DDB2)
Ubiquitin system [BR:ppad04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     109245111 (DDB2)
DNA repair and recombination proteins [BR:ppad03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      109245111 (DDB2)
SSDB
Motif
Pfam: WD40 WD40_Prp19 WD40_WDHD1_1st WD40_CDC20-Fz Beta-prop_EML_2 Beta-prop_WDR75_1st WDR55 Beta-prop_RIG_2nd Beta-prop_WDR90_POC16_2nd Beta-prop_IFT140_1st Beta-prop_EIPR1 EIF3I Beta-prop_WDR19_1st Beta-prop_TEP1_2nd WD40_RFWD3 Beta-prop_CAF1B_HIR1 Beta-prop_TEP1_C NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_Vps41 WD_LRWD1 Beta-prop_WDR35_TULP_N EF-hand_1
Other DBs
NCBI-GeneID: 109245111
NCBI-ProteinID: XP_019267896
Ensembl: ENSPPRG00000005739
UniProt: A0A9V1DUG3
LinkDB
Position
Unknown
AA seq 456 aa
MAPRKRPETQKTPEVVVRPKSRRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPSYTSIVRALHHHKLGKAAWPSLQQGLQQSFVHSLASYRIFQKAAPFDRRATSLAWH
PTHPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSVTGLKFNPLDTNQFFTSSMEGT
TRLQDFKGNTLRVFTSSDTCNIWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRM
HKKKVTHVALNPCCDWLLATASVDQTVKIWDLRQVKGKSSCLHSLLHSHPVNAACFSPDG
AQLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKPSLSPCCSALKLQCLLTSA
LLMTSPVSAPKATWHPRYNLIVVGRYPDPNFKSCTPHELRTIDVFDGSSGKMMYQLYDPE
SSGIISLNEFNPMGDTLASVMGYHILIWSQEAGMRK
NT seq 1371 nt   +upstreamnt  +downstreamnt
atggctcccaggaaacgcccagaaacccagaagacccccgaggtggttgtgcgccccaag
agcaggaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctt
caggtcccgccatcatacaccagcatcgtcagggcccttcaccaccataagctgggcaaa
gctgcctggccatcactacagcagggtctccagcagtcctttgtgcattctctggcttct
taccggatattccaaaaggctgccccttttgacaggagggccacatccttggcatggcac
ccaactcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaac
tttggcataaaggacaaacccaccttcattaaagggattggagctggagggagcgtcact
gggctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaaca
actaggctgcaagactttaaaggcaacacgctccgagtgtttaccagctcagacacctgc
aacatctggttttgcagcctggatgtgtctgccagaagccgaatggtggtcacaggcgac
aatgtgggacatgtgatcctgctgaacatggacggcagggagctttggaatctgagaatg
cacaaaaagaaagtgacccatgtggccctgaacccatgctgtgattggctcctggccaca
gcctctgtggaccaaacagtgaaaatctgggacctgcgccaggttaaagggaaatccagc
tgcctccactcgctgctgcatagccatcctgtcaacgcagcttgtttcagtcctgacgga
gcccagctcctgaccactgaccagaagagtgagctccgggtttactcggcctcccagtgg
gactgccccccgagcctgatcccacaccctcaccgccacttccagcacctgacgcccatc
aagcccagcctatctccctgctgttctgccctcaaacttcagtgcctgctgacctcagcc
ttgctaatgacttctccagtctcagcccccaaggcaacctggcatcctcggtacaacctc
attgtcgtgggccgatacccagatcctaatttcaaaagttgtaccccccatgaattaagg
accattgatgtgtttgatggaagctcagggaagatgatgtatcagctctatgacccagaa
tcttctggtatcatttcgctcaatgagttcaatcccatgggggacacgctggcctctgtg
atgggttatcacattctcatttggagccaggaagctgggatgcggaaatga

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