Panthera pardus (leopard): 109246097 Help Entry 109246097         CDS       T06062                                  Symbol PLD2 Name (RefSeq) phospholipase D2   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism ppad  Panthera pardus (leopard) Pathway ppad00564   Glycerophospholipid metabolism ppad00565   Ether lipid metabolism ppad01100   Metabolic pathways ppad04014   Ras signaling pathway ppad04024   cAMP signaling pathway ppad04071   Sphingolipid signaling pathway ppad04072   Phospholipase D signaling pathway ppad04144   Endocytosis ppad04666   Fc gamma R-mediated phagocytosis ppad04724   Glutamatergic synapse ppad04912   GnRH signaling pathway ppad04928   Parathyroid hormone synthesis, secretion and action ppad05200   Pathways in cancer ppad05208   Chemical carcinogenesis - reactive oxygen species ppad05212   Pancreatic cancer ppad05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     109246097 (PLD2)    00565 Ether lipid metabolism     109246097 (PLD2)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     109246097 (PLD2)    04072 Phospholipase D signaling pathway     109246097 (PLD2)    04071 Sphingolipid signaling pathway     109246097 (PLD2)    04024 cAMP signaling pathway     109246097 (PLD2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109246097 (PLD2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     109246097 (PLD2)   09152 Endocrine system    04912 GnRH signaling pathway     109246097 (PLD2)    04928 Parathyroid hormone synthesis, secretion and action     109246097 (PLD2)   09156 Nervous system    04724 Glutamatergic synapse     109246097 (PLD2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109246097 (PLD2)    05208 Chemical carcinogenesis - reactive oxygen species     109246097 (PLD2)    05231 Choline metabolism in cancer     109246097 (PLD2)   09162 Cancer: specific types    05212 Pancreatic cancer     109246097 (PLD2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ppad04131]     109246097 (PLD2) Enzymes [BR:ppad01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      109246097 (PLD2) Membrane trafficking [BR:ppad04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     109246097 (PLD2)  Endosome - Golgi transport   Others    Others     109246097 (PLD2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLDc PLDc_2 PX PH Motif Other DBs NCBI-GeneID:  109246097 NCBI-ProteinID:  XP_019269399 LinkDB All DBs Position Unknown AA seq 1155 aa AA seqDB search MHPFLAIYDLQPLKMRPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGAFTWT TKKKFRHFQELHRDLLRHKVLMSLLPLARFATTHPPAGEAANREMPSLPRAGPEGSSRHA ASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVP GLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTETRYG VRIDTSHRSLILKCGSYRQARWWGQEITELAQGPGRDFIQLHRHDSYAPPRPRTLARWFV NGAGYFAAVADAIEGAQEEIFITDWWLSPEIYLKRPAHSDDWRLDIMLKKKAEEGVRVSV LLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLD LAYGRWDDLQYRLTDLGDPSEPAAPQPPTPGSDAPATPDLSQNQLFWLGKDYSNLITKDW VQLDRPFEDFIDRETTPRMPWRDVGVAVHGLPARDLARHFIQRWNFTKQVAHMGVSKWLG RWMDGWMDGWMDGWAGEQCAHPLLSLLRASEQGVSTEDPQAECTDIQNPKNGEGFGRLRG GGRSDPPSPAHHQEEGVRVSVLLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTL WAHHEKLLVVDQVVAFLGGLDLAYGRWDDLQYRLTDLGDPSEPAAPQPPTPGSDAPATPD LSQNQLFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVAVHGLPARDLARH FIQRWNFTKTTKAKYKTPVYPYLLPKSTSTADQLSFTIPGGQCATVQVLRSVDRWSAGTV ENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGQRFRVY VLLPLLPGFEGDITTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGL RTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTEMEP SLMDGGEYQAGRFALSLRKHCFSVILGAHARPDLDLRDPVCDDFFQLWQDTAESNANIYE QIFRCLPSNATRSLRVLREYVVVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLP PLGSKEGVMPLEVWT NT seq 3468 nt NT seq  +upstreamnt  +downstreamnt atgcaccctttcctggccatctacgacctgcagcctctgaaaatgcgccccttggtgttc gcccctggggtgcccgtcaccgcccaagtggtgggaaccgaaagatacaccagcggatcc aaggtgggaacctgcactctgtattccgtccgcttgactcacggcgcctttacctggacg accaagaagaagttccgtcatttccaggagctgcaccgggacctcctgaggcacaaagtc ttgatgagtctgctccctctggcccgctttgccaccacccatccccccgccggagaagcc gccaaccgcgagatgccctctctgcctcgcgcaggacccgagggctcctccagacacgcg gccagcaaacagaaatacctggagaattacctcaaccgcctcctgaccatgtctttctac cgcaactaccacgccatgacggagttcctggaagtcagccagctctccttcatcccagac cttggctccaaaggactggaaggagtgatccggaagcgctcgggcggccaccgcgttcct ggcctcacctgctgtggccgggaccaagtgtgttaccgctggtccaagaggtggctggtg gtgaaggactctttcctgctgtacatgtgcctcgagacgggcgccatctcctttgttcag ctctttgaccctggcttcgaggtgcaggtggggaaacggagcactgagacgcggtacggg gtcaggatcgacacctcccacaggtccctgatcctcaagtgtggcagctaccggcaggca cggtggtggggccaggagatcacggagctggcccagggcccgggaagagacttcatacag ctgcaccgtcatgacagctatgccccaccccggcccaggaccttggcccggtggtttgtg aacggggcgggttactttgccgctgtggcagacgccatcgaaggagctcaagaggagatt ttcatcacagactggtggttgagtcctgagatttacctgaagcgtccggcccattcagat gactggagactggacattatgctcaagaagaaggcggaggagggtgtccgtgtgtccgta ctgctgtttaaggaggtggagctggccttgggcattaacagcggctacagcaagagggct ctgatgctgctgcaccccaacataaaggtgatgcgccacccggaccaggtgacgctgtgg gcccatcatgagaagctcctggtcgtggaccaagtagtagccttcttgggggggctggac ctcgcctacggccgctgggacgacctgcagtaccggctgactgacctcggggacccctct gaaccagccgccccgcagcctcccacccccggctcagatgctccggccaccccagacctg tcccaaaaccaactcttctggctgggcaaggactacagcaatcttatcactaaggactgg gtgcagctggaccggccttttgaggatttcatcgacagggagaccacgccccggatgcca tggcgggacgtaggggtggccgtccacggtctgcccgcccgggacctggcccgccacttc atccagcgctggaatttcaccaagcaggtggcacatatgggggtgagtaaatggctggga agatggatggatggatggatggatggatggatggatggatgggcgggtgaacagtgtgct caccccctgctaagtttgctgagagcatcagagcagggtgtgagcactgaggatccccag gctgagtgcacggatatacagaaccccaagaatggggaaggattcgggaggttgcggggg gggggccgttctgaccccccctcccccgctcaccaccaggaggagggtgtccgtgtgtcc gtactgctgtttaaggaggtggagctggccttgggcattaacagcggctacagcaagagg gctctgatgctgctgcaccccaacataaaggtgatgcgccacccggaccaggtgacgctg tgggcccatcatgagaagctcctggtcgtggaccaagtagtagccttcttgggggggctg gacctcgcctacggccgctgggacgacctgcagtaccggctgactgacctcggggacccc tctgaaccagccgccccgcagcctcccacccccggctcagatgctccggccaccccagac ctgtcccaaaaccaactcttctggctgggcaaggactacagcaatcttatcactaaggac tgggtgcagctggaccggccttttgaggatttcatcgacagggagaccacgccccggatg ccatggcgggacgtaggggtggccgtccacggtctgcccgcccgggacctggcccgccac ttcatccagcgctggaatttcaccaagacgaccaaggccaagtacaagacccccgtgtac ccctacctgctgcccaaatccaccagcaccgcggaccagctctccttcacgatcccaggg gggcagtgcgccactgtgcaggtcttgcggtcggtggaccgttggtcagcagggacagtg gaaaactccatcctcaatgcctacctgcacaccatcagggagagccagcacttcctgtac atcgagaatcagttctttattagctgctcggacgggcggaccgttctgaacaaggtgggc gatgagattgtggacagaatcctgaaggcccacaaacaggggcagcgtttccgagtctac gtgcttctgcccctgctgccggggtttgaaggtgacatcacgacaggtggtggtaactcc atccaggccattctgcacttcacttacaggaccctgtgccgtggggaatattcgatccta catcgcctcaaagcagccatggggacagcgtggcgggactacatatccatctgcgggctt cgcacacacggagagctgggcgggcacccggtctccgaactcatctacatccacagcaag atgctcatcgcagatgaccggacggtcatcatcggctctgccaacatcaacgaccggagc ttgctggggaagcgagacagtgagctggccgtgctgatcgaggacacagagatggaacca tccctcatggacggtggggagtatcaggcgggccggtttgctttgagtctgcggaagcac tgcttcagtgtgattctcggggcacacgcccggccagacctggatctccgagaccctgtc tgtgatgacttctttcagctgtggcaggacacagccgagagcaatgccaatatctatgag cagatcttccgctgcctgccatccaatgccacacgctctctcagggtgctccgggagtat gtggtcgtggagcccctggccacagtcagcccacctctggcccggtctgagctcacccag gtccagggccacctggtccactttcccctcaagttcctggaggatgagtctttgctgccc cccctggggagcaaggaaggcgtgatgcccctcgaagtgtggacatag

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