Panthera pardus (leopard): 109247511
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Entry
109247511 CDS
T06062
Symbol
NOTCH3
Name
(RefSeq) neurogenic locus notch homolog protein 3
KO
K20995
Notch 3
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01522
Endocrine resistance
ppad04330
Notch signaling pathway
ppad04371
Apelin signaling pathway
ppad04658
Th1 and Th2 cell differentiation
ppad04919
Thyroid hormone signaling pathway
ppad05165
Human papillomavirus infection
ppad05200
Pathways in cancer
ppad05206
MicroRNAs in cancer
ppad05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
109247511 (NOTCH3)
04371 Apelin signaling pathway
109247511 (NOTCH3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
109247511 (NOTCH3)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
109247511 (NOTCH3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109247511 (NOTCH3)
05206 MicroRNAs in cancer
109247511 (NOTCH3)
09162 Cancer: specific types
05224 Breast cancer
109247511 (NOTCH3)
09172 Infectious disease: viral
05165 Human papillomavirus infection
109247511 (NOTCH3)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
109247511 (NOTCH3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
Ank_2
Ank
Notch
EGF_2
NODP
Ank_4
NOD
Ank_3
Ank_5
EGF_3
cEGF
JAG1-like_EGF2
DL-JAG_EGF-like
Motif
Other DBs
NCBI-GeneID:
109247511
NCBI-ProteinID:
XP_019271678
Ensembl:
ENSPPRG00000014001
LinkDB
All DBs
Position
Unknown
AA seq
2290 aa
AA seq
DB search
MSNIGETPPCLDGSRCMNGGHCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVC
QSSVVAGAARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRYLCSCPPGYQGR
SCRSDVDECRVGGPCRHGGTCLNTPGSFRCQCPAGYTGPLCENAAVPCAPSPCRNGGTCR
QSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTE
DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV
ASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD
ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQF
TCICMAGFTGTYCEVDVDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGAMCQLDVDECAS
TPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPG
YTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGV
CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGDGGSCVDGENGFRCLCPPGSLPPLCL
PTSHPCAQEPCSHGVCHDAPGGFRCMCEPGWSGPRCSQSLARDACESQPCRSGGTCTTDG
IGFHCTCPPGVQGRQCELPSPCTPNPCEHGGHCESAPGQLPVCSCPPGWQGPRCQQDVDE
CAGPSPCGSHGTCTNLAGSFSCTCHEGYSGPSCDQDIDDCDPNPCLNGGSCQDGVGSFSC
SCLPGFAGPRCAREVDECLSSPCGPGTCTDHVASFTCTCPPGYGGFRCEQDLPDCSPSSC
FHGGTCVDGVNSFSCQCRPGYTGAHCQHEADPCVSRPCLHGGVCTAAHPGFRCTCPEGFT
GAQCQTLVDWCSHAPCQNGGRCARSGASFYCLCPPGWSGRVCDIRSVPCREAAAQIGVRL
EELCQTGGQCVDKDNSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYVCECP
AGYTGDNCEGDVDECASQPCQNGGFCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLD
QGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECHPGACHDAHTRDCLQDPGGGFR
CLCRAGFTGPRCQTVLSPCESQPCQHGGQCRPSPGPGGMLTFTCRCVPPFWGPRCERVAR
SCRELQCPAGVPCQQTVRGPRCACPPGLSGPACRGSRGSPPGAANASCLASPCLHGGSCG
PAPLAPFFRCACAPGWDGPRCEVPAAAPEAPEEPLCPSAACEAKSGDKRCDRECNSPGCG
WDGGDCSLSVGDPWRQCAALQCWRLFNNSRCDPACSSPACLYDNFDCRAGGRERACNPVY
EKYCADHFADGRCDQGCNTEECGWDGLDCAGEVPALLARGVLVLTVLLPPEELLRSSADF
LQRLSGILRTSLRFRLDEHGQAMVFPYHRPGPGAESRNRRELAPEVIGSVVMLEIDNRLC
LQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRAVRGEPLELPEPSMPLLPLLAASA
VFLLAILVLGVMVARRKREHSTLWFPEGFALHKDVAAGHKGRREPVGQDALGMKNMAKSE
SLMGQVATDWMDTECPEAKRLKVEDPGVGAEDAVDCRQWTQHHLVAADIRVAPAMALTPP
QGDVDADGVDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEAEDASASIISDLICQGAQL
GARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQIL
IRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNN
VEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDV
AQERLHQDIVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPGLKVAQSGGKKSRRPPGKAG
LGPQGARGRGKKLTLACPGPLAESSVTLSPVDSLDSPRPFGGPPASPGGFSLEGPYAAAT
ATAVSLAQLGGASRAGLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAP
GPQLLNPGTPVSPQERPPPYLAAPGHGEEYPAAGAHGSPPKARFLRVPSEHPYLTPSPES
PEHWASPSPPSLSDWSDSTPSPATATGPAATAAGALPAQPLPLSVPGPLAQAQTQLGPQP
EVTPKRQVLA
NT seq
6873 nt
NT seq
+upstream
nt +downstream
nt
atgtccaacatcggggaaacccccccttgcctggacggaagccggtgtatgaatggaggt
cactgcacccagctgccctcccgggaggctgcctgcctgtgccctccaggatgggtgggc
gagcggtgccagctggaggacccctgccattcgggcccctgtgctggccgtggtgtctgc
cagagctcggtggtggcaggcgctgcccggttctcctgccgctgcccccgtggcttccgg
ggtcccgactgctctctgccggacccctgcctcagcagcccctgtgcccatggtgcccgc
tgctccgtggggcccgatggccgctacctctgctcctgcccgcctggctaccagggccgc
agctgccgaagcgatgtggatgagtgccgggtgggagggccatgccgccacggtggcacc
tgcctcaacacgcctggttccttccgctgccagtgcccagctggctacacggggccactg
tgtgagaacgctgcagtgccctgcgccccctcgccgtgccgaaacgggggcacgtgtaga
cagagtggcgacctcacctacgactgtgcctgccttcctgggttcgagggccagaactgt
gaagtgaatgtggatgactgtccagggcaccgctgtctaaatgggggcacgtgtgtggat
ggcgtcaacacctacaactgccagtgccctcctgagtggacaggccaattctgcacggag
gacgtggatgaatgccagctgcagcccaatgcttgccacaacgggggcacctgtttcaac
acactgggtggccacagctgtgtgtgtgtcaacggctggacaggcgagagctgcagtcag
aatatcgatgactgtgccacggccgtgtgcttccatggggccacctgccatgaccgcgtg
gcctcgttctactgtgcctgtcccatgggcaagactgggcttctgtgtcatctggatgac
gcctgtgtcagcaacccctgtcacgaggatgctatctgtgacacgaacccggtgaacgga
cgggccatctgcacctgtccaccaggcttcaccggcggggcatgtgaccaggatgtggat
gagtgctccattggcgccaacccgtgtgagcacctgggccggtgtgtgaacacacagggc
tcattcctgtgccagtgtggccgtgggtacacaggcccgcgctgcgagaccgacgtcaac
gagtgcctatcggggccctgccgcaaccaggccacgtgcctcgaccgcataggccagttc
acctgcatctgcatggcaggctttacaggcacctattgtgaggtggacgtggatgagtgt
cagagcagcccgtgtgttaatggcggggtctgcaaggacagagtcaacggcttcagctgc
acctgcccctcgggcttcagcggggccatgtgtcagctggatgtggatgagtgcgccagc
acaccttgccggaatggagccaaatgtgtggaccagcccgatggctacgaatgtcgctgc
gcagagggtttcgaaggcactctgtgtgaacgcaacgtggatgactgttccccggacccg
tgccaccacgggcgctgtgtggatggcatcgccagcttctcctgcgcctgtgccccggga
tacacaggcacacgctgtgaaagccaggtggacgagtgccgcagccagccctgccgccac
ggaggcaaatgtctagacttggtggacaagtatctctgccgctgccctcccggcaccaca
ggagtgaactgcgaggtgaacattgatgattgtgccagcaacccctgcacctttggagtc
tgccgggatggcatcaaccgctatgactgtgtctgccagcctggcttcacagggcccctt
tgcaacgtggagatcaatgagtgtgcgtccagcccgtgcggtgacggaggctcctgtgtg
gatggggaaaatggcttccgctgcctctgcccacctggctccctgcccccgctctgcctt
cccacgagccatccctgtgcccaagaaccctgcagtcacggtgtctgccacgatgcaccc
ggagggttccgctgcatgtgtgagcctggctggagtggcccccgatgcagccagagcctt
gctcgagatgcctgtgaatcccagccctgccggtctggtggcacctgcaccactgatgga
atcggcttccactgtacctgtccccctggtgtccagggccgtcagtgtgagctgccatcg
ccctgtactccaaacccctgtgagcatgggggtcactgtgagtctgcccctggccagctg
cctgtctgctcctgccctcctggctggcaaggcccacgatgccagcaggatgtggatgaa
tgtgctggcccctcaccctgtggctcccacggtacctgcaccaacctggcagggagtttc
agctgtacctgccacgaggggtacagtggcccttcctgtgatcaggacatcgatgactgt
gaccccaacccctgcctgaatggtggctcctgccaggatggcgtgggctccttttcatgc
tcctgcctccctggctttgctggtccccgctgtgcccgcgaggtggatgagtgtctgagc
agcccctgtggcccgggcacctgtaccgaccacgtggcctcctttacctgcacgtgccca
cctggatatggaggcttccgctgtgagcaggacctacccgactgcagccccagctcctgc
ttccacggcgggacctgcgtggacggtgtgaactcgttcagctgccagtgccgccctggc
tacaccggcgcacactgccaacacgaggccgacccctgcgtctctcggccctgcctgcac
gggggcgtctgcacggccgcccaccctggcttccgctgcacctgtccggagggcttcact
ggcgctcagtgccagacgctggtagactggtgcagccacgcgccctgtcagaacgggggt
cgctgtgcccggagcggggcctccttctactgcctttgccctccgggttggagcggccgc
gtctgtgacatccggagtgtgccctgcagggaggccgcagcccagatcggggtgcggctg
gaagagctgtgtcagactggtgggcagtgcgtggacaaggacaattcccactattgcgtg
tgtccagaaggccgcacgggcagccactgtgagcaggaggtggacccctgcttggcccag
ccctgccagcatgggggcacctgccgcggctacatggggggttatgtgtgcgagtgtcca
gctggctacaccggggacaactgtgagggtgatgtggacgagtgcgcctcccagccctgc
cagaacgggggcttctgcattgacctcgtggcccgctatctctgctcctgccccccggga
acgctgggtgtgctctgtgagattaatgaggacgactgtggcccaggcccacccctggac
cagggcccccggtgcctgcacaatggtacctgtgtggacctcgtgggtggctttcgctgc
acctgcccccccgggtacactggcctgcgctgcgaggcggacatcaatgagtgtcacccg
ggtgcctgccacgatgcacacacccgggattgtctgcaggacccaggtgggggcttccgc
tgcctttgtcgtgcgggcttcacaggtccccgctgtcagactgtcctgtctccctgtgag
tcccagccatgccagcacggaggccagtgccgtcccagcccaggacctgggggtatgctg
acatttacctgccgctgcgttccgcccttctggggcccgcgttgcgagcgggtggcgcgc
tcctgccgggagctgcagtgcccggcgggcgtcccgtgccagcagacggtccgtgggccg
cgctgcgcctgccccccgggactgtcggggcccgcctgccggggctcgcgggggtcgccg
ccgggggccgccaacgccagctgcctggcctccccctgcctccacggcggctcctgcggc
cccgcgcccctcgcacctttcttccgctgcgcgtgcgcgccaggctgggacggaccgcgc
tgcgaggtgcccgcggcggcgcccgaggcccccgaggagccgctgtgcccgagcgccgcc
tgcgaggccaagagcggggacaagcgctgcgaccgcgagtgcaacagcccgggctgcggc
tgggacggcggcgactgctcgctgagtgtgggcgacccctggcggcagtgcgcggcgctg
cagtgctggcgcctcttcaacaacagccgctgcgaccccgcctgcagctcgcccgcctgc
ctctatgacaacttcgactgccgcgcgggcggccgcgagcgcgcctgcaaccccgtgtac
gagaagtactgtgcggaccactttgcggacggccgctgcgaccagggctgcaacacggag
gagtgcggctgggacgggctggactgcgcgggcgaggtgcccgccctgctggcccgcggc
gtgctggtgctcaccgtgctgctcccgcccgaggagctgctgcgctccagcgccgacttc
ctgcagcggctgagcggcatcctgcgcacgtcgctgcgcttccgcctggacgaacacggt
caggccatggtcttcccgtaccaccggcccggccctggcgccgaatcccggaaccggcgg
gagctggccccggaggtgatcggctctgtggtgatgctggagattgacaaccggctgtgc
ctgcagtcaccggagaacgaccactgcttccccgacgcccagagtgcggccgactacctg
ggagccttgtcggcggtggaacgccttgacttcccgtacccgctgcgggccgtgcgaggg
gagccgctggagctgccggagccgagcatgccgctgcttccgctgctggccgccagcgcc
gtcttcctgctggccatcctcgtgctgggcgtcatggtggcccggcgcaagcgtgagcac
agcaccctctggttccccgagggcttcgcgctccacaaggacgtggctgccggccacaag
ggccgccgggagcccgtgggccaagacgcgctgggcatgaagaacatggccaagagtgag
agtctgatggggcaggtggccacagactggatggacaccgagtgcccagaagcgaagcga
ctgaaggtagaggaccctggcgtgggggccgaggatgctgtggattgtcgccagtggact
caacaccacctggttgcagctgacatccgtgtggcaccagccatggccttgacgccccca
cagggcgatgtggatgctgatggcgtggatgtcaacgtgcgtggcccagatggcttcacc
ccactgatgctggcctctttctgtggcggggctctggagccaatgcccaccgaggaggat
gaggcagaagacgcgtcagcgagcatcatctcagacctgatctgccagggagcccagctt
ggggcacggactgaccgcacgggcgagacagccctgcacctcgctgcccgctatgcccgg
gccgatgcggccaagcggctgctggatgccggggcagacaccaatgcccaggaccattca
ggccgcactcctttgcacactgctgtcaccgctgatgcccaaggcgtcttccagattctc
atccggaaccgttccacagacctggatgcccgcatggcggatggttcaacggcgctaatc
ctcgcagcccgtctggcggtggagggcatggtggaagaactcattgccagccatgctgat
gtcaatgctgtggatgagcttgggaaatcagccttacactgggcagcagccgtcaacaat
gtggaggccacgttggccctgctcaaaaatggagccaacaaggacatgcaggatagcaag
gaggaaactccactctttctggctgcccgggagggcagctatgaggctgccaagctgctg
ctggaccacttcgccaaccgcgagatcacagaccacctggacaggctgccgcgggacgtg
gcccaggagcggctgcaccaggacatcgtgcgcctgctggaccagcccagtgggccccgg
agccctcccggcccgcacggcctggggcccctcctctgcccaccgggggccttcctcccg
ggcctcaaggtggcacagtctgggggcaagaagagccggaggccacccgggaaggcgggg
ctggggccgcagggcgcccgggggcggggcaagaagctgacgctggcctgccccggtccc
ctggccgagagctcggtcacgctgtcgcccgtggactcgctggactccccgcggcccttc
ggtgggccccccgcgtcccctggcggcttctccctcgaggggccctacgcggctgccacc
gccacggctgtgtccctggcgcagctcggtggcgcgagccgggccggtctagggcgccag
ccccccgggggctgcgtgctcagcttgggtctgctgaaccccgtggccgttcccctcgac
tgggcccggctgccgccacctgccccgccgggcccctcgttcctgctgccgctggcgccg
ggaccccagctgctgaaccccgggacccccgtgtcgccccaggagcggcccccaccgtac
ctggcggccccgggacacggcgaggagtacccggcagccggcgcccacggcagccccccc
aaggcccgcttcctgagggtccccagcgagcacccttacctgaccccctcccccgagtcc
cccgagcactgggccagcccctcgcctccctccctctcggactggtcagactccacgccc
agcccagccactgccaccgggcccgcggccacagccgctggggcgctgcctgcccagccg
ctccccctttccgttccaggcccgctagctcaggcccagacccagctggggccccagccc
gaagtcacccccaagaggcaggtgttggcctga
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integrated database retrieval system
