KEGG   Panthera pardus (leopard): 109247805
Entry
109247805         CDS       T06062                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04014  Ras signaling pathway
ppad04015  Rap1 signaling pathway
ppad04022  cGMP-PKG signaling pathway
ppad04024  cAMP signaling pathway
ppad04062  Chemokine signaling pathway
ppad04071  Sphingolipid signaling pathway
ppad04072  Phospholipase D signaling pathway
ppad04081  Hormone signaling
ppad04144  Endocytosis
ppad04150  mTOR signaling pathway
ppad04270  Vascular smooth muscle contraction
ppad04310  Wnt signaling pathway
ppad04350  TGF-beta signaling pathway
ppad04360  Axon guidance
ppad04510  Focal adhesion
ppad04520  Adherens junction
ppad04530  Tight junction
ppad04611  Platelet activation
ppad04621  NOD-like receptor signaling pathway
ppad04625  C-type lectin receptor signaling pathway
ppad04660  T cell receptor signaling pathway
ppad04670  Leukocyte transendothelial migration
ppad04722  Neurotrophin signaling pathway
ppad04810  Regulation of actin cytoskeleton
ppad04921  Oxytocin signaling pathway
ppad04928  Parathyroid hormone synthesis, secretion and action
ppad04972  Pancreatic secretion
ppad05100  Bacterial invasion of epithelial cells
ppad05132  Salmonella infection
ppad05133  Pertussis
ppad05135  Yersinia infection
ppad05152  Tuberculosis
ppad05163  Human cytomegalovirus infection
ppad05200  Pathways in cancer
ppad05203  Viral carcinogenesis
ppad05205  Proteoglycans in cancer
ppad05206  MicroRNAs in cancer
ppad05210  Colorectal cancer
ppad05417  Lipid and atherosclerosis
ppad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    109247805 (RHOA)
   04015 Rap1 signaling pathway
    109247805 (RHOA)
   04310 Wnt signaling pathway
    109247805 (RHOA)
   04350 TGF-beta signaling pathway
    109247805 (RHOA)
   04072 Phospholipase D signaling pathway
    109247805 (RHOA)
   04071 Sphingolipid signaling pathway
    109247805 (RHOA)
   04024 cAMP signaling pathway
    109247805 (RHOA)
   04022 cGMP-PKG signaling pathway
    109247805 (RHOA)
   04150 mTOR signaling pathway
    109247805 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109247805 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    109247805 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109247805 (RHOA)
   04520 Adherens junction
    109247805 (RHOA)
   04530 Tight junction
    109247805 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109247805 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109247805 (RHOA)
   04621 NOD-like receptor signaling pathway
    109247805 (RHOA)
   04625 C-type lectin receptor signaling pathway
    109247805 (RHOA)
   04660 T cell receptor signaling pathway
    109247805 (RHOA)
   04670 Leukocyte transendothelial migration
    109247805 (RHOA)
   04062 Chemokine signaling pathway
    109247805 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    109247805 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    109247805 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    109247805 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    109247805 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    109247805 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    109247805 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109247805 (RHOA)
   05206 MicroRNAs in cancer
    109247805 (RHOA)
   05205 Proteoglycans in cancer
    109247805 (RHOA)
   05203 Viral carcinogenesis
    109247805 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109247805 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    109247805 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109247805 (RHOA)
   05135 Yersinia infection
    109247805 (RHOA)
   05133 Pertussis
    109247805 (RHOA)
   05152 Tuberculosis
    109247805 (RHOA)
   05100 Bacterial invasion of epithelial cells
    109247805 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109247805 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    109247805 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ppad04131]
    109247805 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ppad04147]
    109247805 (RHOA)
   04031 GTP-binding proteins [BR:ppad04031]
    109247805 (RHOA)
Membrane trafficking [BR:ppad04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    109247805 (RHOA)
Exosome [BR:ppad04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   109247805 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   109247805 (RHOA)
  Exosomal proteins of colorectal cancer cells
   109247805 (RHOA)
  Exosomal proteins of bladder cancer cells
   109247805 (RHOA)
GTP-binding proteins [BR:ppad04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    109247805 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 109247805
NCBI-ProteinID: XP_019272362
Ensembl: ENSPPRG00000024656
UniProt: A0A9V1E1V8
LinkDB
Position
Unknown
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggcaagacttgc
ttgctcatcgtctttagcaaggaccagttcccagaggtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatggaaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccggacaccgatgttata
ctgatgtgtttctccattgacagccctgatagtttagaaaacatcccagaaaaatggact
ccggaagtcaagcacttctgtcccaatgtgcccatcattctggttggaaacaagaaggat
cttcggaatgatgagcacacaaggcgggagctggccaagatgaagcaggagccagtgaaa
ccagaagaaggcagagatatggcaaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagccgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

DBGET integrated database retrieval system