Panthera pardus (leopard): 109248689
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Entry
109248689 CDS
T06062
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00230
Purine metabolism
ppad01100
Metabolic pathways
ppad04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
109248689 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
109248689 (PDE5A)
Enzymes [BR:
ppad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
109248689 (PDE5A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
109248689
NCBI-ProteinID:
XP_019274097
Ensembl:
ENSPPRG00000002118
UniProt:
A0A9V1E501
LinkDB
All DBs
Position
Unknown
AA seq
865 aa
AA seq
DB search
MERASPGPGGSQLQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKE
GIRSHTESCSCPSQQSPRADSSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEK
KEQMPLTPPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYRTQSILCMPIKNHREEVVGVAQAINKRSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKD
KRFPWTNENTGSVSQQFIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAVAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNR
QKWQALAEQQEKMLINGESSQAKRN
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggccagcccgggccccggggggtcgcagttgcagcgggaccaggattcggtg
gaagcgtggctggatgatcactgggactttaccttctcttactttgttaggaaagccacc
agagaaatggtcaatgcctggtttgctgagagagtccacaccatccctgtgtgcaaagaa
ggtatcagaagccacacagaatcttgctcttgcccctcgcagcagagtccccgtgcagat
agcagtgcacctggaacaccaaccaggaaaatctctgcctccgaatttgaccggcctctt
agacccattgttgtcaaggattctgagggaaccgtgagcttcctctctgactcagaaaag
aaggaacagatgcctctaacccccccaaggtttgataatgatgaaggggaccagtgctca
agactcttggaattagtgaaagatatctctagtcatttggatgtcacagccttatgtcac
aaaattttcttgcatattcatggacttatctctgccgatcgctattccctgttccttgtc
tgtgaggacagctccaacgacaagtttcttatcagccgcctgtttgatgttgcagaaggt
tcaacactggaagaagcttcaaataactgtatccgcttagaatggaacaaaggcattgtg
ggacatgtggcagcatttggtgagcccttaaacatcaaagatgcttacgaggatcctcgg
ttcaatgcagaagttgaccaaattacaggctacaggacacaaagtattctttgtatgccg
attaagaatcatagggaagaggttgttggtgtagcccaggccatcaacaagagatcggga
aatggtgggacattcactgaaaaagatgaaaaggactttgctgcctatttggcattttgt
ggtattgttcttcataatgctcaactctatgagacttcactgctggagaacaagagaaat
caggtgctgcttgaccttgctagcttaatttttgaagaacagcaatcattagaagtaatt
ctaaagaaaatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattctttttctagtgtgtttcacatggagtgtgaagaa
ttagaaaaatcatcagatactttaacaagggagcgtgatgcaaacagaatcaattacatg
tatgctcagtatgtaaaaaatactatggaaccacttaatatcccagatgtcagtaaagac
aaaagatttccctggacaaatgaaaacacaggaagcgtaagtcaacagttcattagaagt
ttgctttgtacgcctataaaaaatggaaagaagaataaagtgataggggtttgccaactt
gtaaataagatggaggagaatactggcaaggttaagcctttcaaccgaaatgacgaacag
tttctggaggcttttgtcatcttttgtggcttggggatccagaacacacagatgtatgaa
gcagtggagagagccatggccaagcaaatggtcacactggaggttctgtcgtatcacgct
tcagcagcagaggaagaaacaagagagctccaatccttagcggttgctgttgtaccatct
gctcagacacttaaaattactgacttcagtttcagtgactttgagctgtctgacctagaa
acggcactgtgtacaattcggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcaggtggattttaagtgttaagaagaattaccggaagaatgtt
gcctatcataattggagacacgcctttaatacagctcagtgcatgtttgctgctctaaaa
gcaggcaagattcagaacaagctgaccgacctagagacactcgccctgctgattgctgct
ctcagccacgacttggaccaccgtggtgtgaataactcttacatacagcgaagtgaacac
ccacttgctcagctctactgccattcgatcatggagcatcatcactttgaccagtgcctg
atgattcttaatagtccaggcaatcagattctcagtggcctctccatcgaagaatataag
accacgctgaaaataatcaagcaagctattttagctacagacctagcgctgtatattaag
agacgaggagaattttttgaacttataagaaaaaatcaattcaacttggaagatcctcat
caaaaagagttgtttttagcgatgctgatgacagcttgtgatctctctgcaattacaaaa
ccctggcctattcaacaacggatagcagaacttgtagcaactgaattttttgaccaagga
gacagagagagaaaagaactcaacatagagcctgctgatctgatgaacagggagaagaaa
aacaaaatcccaagtatgcaagttgggttcatagatgccatctgcttgcaactatatgag
gccttgacccacgtttctgaggactgtttccctttgctggatggctgcaggaagaacagg
caaaaatggcaggctcttgcagaacagcaggagaaaatgctgattaatggggaaagcagt
caggccaagcggaactga
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