Panthera pardus (leopard): 109249982 Help Entry 109249982         CDS       T06062                                  Symbol TSC1 Name (RefSeq) hamartin isoform X1   KO K07206   tuberous sclerosis 1 Organism ppad  Panthera pardus (leopard) Pathway ppad04072   Phospholipase D signaling pathway ppad04140   Autophagy - animal ppad04150   mTOR signaling pathway ppad04151   PI3K-Akt signaling pathway ppad04152   AMPK signaling pathway ppad04211   Longevity regulating pathway ppad04218   Cellular senescence ppad04714   Thermogenesis ppad04910   Insulin signaling pathway ppad05163   Human cytomegalovirus infection ppad05165   Human papillomavirus infection ppad05168   Herpes simplex virus 1 infection ppad05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ppad00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     109249982 (TSC1)    04151 PI3K-Akt signaling pathway     109249982 (TSC1)    04152 AMPK signaling pathway     109249982 (TSC1)    04150 mTOR signaling pathway     109249982 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     109249982 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     109249982 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109249982 (TSC1)   09149 Aging    04211 Longevity regulating pathway     109249982 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     109249982 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109249982 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     109249982 (TSC1)    05163 Human cytomegalovirus infection     109249982 (TSC1)    05165 Human papillomavirus infection     109249982 (TSC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  109249982 NCBI-ProteinID:  XP_019276224 Ensembl:  ENSPPRG00000002602 UniProt:  A0A9V1E8J1 LinkDB All DBs Position Unknown AA seq 1161 aa AA seqDB search MAQQANIGELVSMLDSPVLSVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPVLHI LTTLQEPHDKHLLDKMNDCVGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KVDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGDSVSPQVSAHFPHRAADVAASPYVDT QNSCGSATSTPYSSSRLTLLNTPGQPPQTLSPPSTRLLAEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPLCHPDDYVHPSVLQATATPPRK EERTDSARPCLHRQHHLPNDRGLEELPGSKGSVTLSDLPGFLGDLASEEDSVEKDKEEAA ISKELSEITTADAELLVPRGGFDSPFYRDSLPGCPRKTHSAASVAHGTSVNPEPLNSSLD KLGPDAPKQAFTPIDLPCGGTSESPAGNRERQASLETNILTPSPCKIPPQRGVGLGSGQP PPYEHLFEVALPKTAHHFVGKKTKELLKKAKGNAEEDHAPSTSPVEILDRLIQQGADAHS KELNRLSLPSKSVDWTHFGGSPPSDEIRTLRNQLLLLHNQLLYERFKRQQHALRNRRLLR RVTRAAALEEHNAAMKDQLKLQEKDIQIWKVSLQKEQARNSQLQEQRDTMVTQLHSQIRQ LQHDREEFYNQSQELQTKLEDCRNMIAELRLELKKANSKVCHTELLLSQVSQKLSNSESV QQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTEEVEMMKAAYRKELEKNRSHVLQQNQR LDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRISQVFELE ILDLYGRLEKDSLLKKLEEENAEAAEAAEERLACCKDGCSDSVTGHNEEAPGHNGETKPP RPAGVRGGGGSRGGGSGELSTPEKPPGQRAGPFGSRWETTTGEPATSIPTTVGSLPSSKS FLGRKARELFRNKSESQCDEDSVTISSLSETLKTEPGQDPGAEGKAPPSLDGPHPSPPTP DSVGQLHIMDYNETHHEHSEG NT seq 3486 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagccaacatcggggagctcgtctccatgctggactcccccgtgctgagc gtgcgtgatgacgtaacagccgtcttcaaagagaacctcaattctgaccgtggtccgatg ctcgtaaacaccttagtggattattacctggaaaccagttctcagccggtattgcacatc ctgacgaccctgcaggagccgcacgataagcacctcctggacaaaatgaacgactgtgtg ggcagagccgcctcgcggttgcccgccctgtcgttgctgggccacgtcatcaggctgcag ccgccctggaagcacaagctgtctcaagcacctcttttgccttctttgctcaaatgtctc aaggtggacaccgatgtcattgtcctcacaacaggtgtcttagtgttgataaccatgcta ccaatgattccacagtcggggaagcagcaccttcatgatttctttgatatttttggccgt ctttcgtcgtggtgcctgaagaaaccaggccacgtgacggaaatctatcttgtccatctc cacgccagcgtctacgctctttttcatcgcctctatggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacactttcgaagaggtggtc aggccgatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccac gaactggaccctcgaaggtggaagagattagaaacgcacgatgttgtgatagagtgtgcc aaaatctctctggaccccacagaagcctcgtatgaagacggcgactctgtgtccccccag gtgtcagcacactttcctcatcgtgcggccgatgtggccgccagcccttacgtcgacacg cagaatagctgtgggagtgctacctcgaccccttattccagctctcggctgacattgtta aatacgcccgggcagccacctcagactctgagtcccccatcaacacggctgctggctgag ccgccacaagctactctctggagcccatctatggtttgtggtatgaccactcctccaact tctcctggaaacgtcccacctgacctgtcacacccttacagtaaagtctttggtacaact ggtggaaaagggactcctctgggaaccccagcaacttctcctcctccagccccactctgc cacccggacgactacgttcacccatccgtcctgcaggccacggccacgccccccaggaag gaagagagaacagattcagcaaggccctgtctacacagacaacaccatcttccgaatgac agaggattagaagagctacctggcagcaaaggttctgtcactctcagtgaccttccaggg tttctaggggacctggcctcggaagaagatagtgttgaaaaagataaagaagaagcggca atatctaaagagctctccgagatcaccacagctgacgccgagctcctggttcctcgagga ggcttcgactctcccttctaccgggacagtctcccgggctgccctcggaagacccattcg gccgcctccgttgcgcacggcaccagtgtgaaccctgagcctttaaactcctccctggac aagcttgggcctgacgcaccaaagcaagcctttactcccatagatctgccctgtggaggc accagcgagagccctgccgggaacagggagcgccaggcgtcgctggagaccaacatcctc actcccagcccttgtaaaatcccgcctcagaggggcgtgggccttggaagtgggcagcct cccccttacgagcatctttttgaggtggcattgccaaagaccgcccatcacttcgtcggc aagaagaccaaggaactgttaaagaaagcgaaaggaaacgcggaggaagaccatgcgccc tctacctccccagtggaaatactggatagactgatacagcagggagcggacgcacacagc aaggagctgaacaggttgtctttacccagcaagtctgtcgactggacccactttggaggc tctcctccctcagatgagatccgcaccctccgtaaccagttgcttttactgcacaaccag ctgctctatgagcgttttaagaggcagcagcacgctctccggaacaggcgactcctccgt cgggtgaccagggcggcggctctggaggagcacaacgccgccatgaaagaccagctgaag ttacaagagaaggacatccagatatggaaggtcagtctgcagaaggaacaagccagaaac agtcagctgcaggagcagcgagacacgatggtgacccagctccacagccagatcagacag ctgcagcacgaccgagaggagttctacaaccagagccaggagctgcagacaaagctggag gactgcaggaacatgatcgcagagctgcgtctggagttgaagaaggccaacagtaaggtg tgccataccgagctgctgctcagtcaggtctcccagaagctctcgaacagcgagtcggtc cagcagcagatggagttcttgaacaggcagctgctggtcctcggggaggtcaacgagctg tatctggagcagctgcagaacaagcactcggacaccacagaggaagtggaaatgatgaaa gctgcatatcggaaagaattagaaaaaaacagaagccatgtcctccagcagaatcagagg ctcgacacctctcagaaacggattttggaactggaatctcacctggccaagaaagaccac cttcttttggaacagaagaaatatttagaggatgtcaaactgcaggccagaggacagctg caggcggcagagagcaggtatgaggctcagaagaggatcagccaggtgtttgagttggag atcttagatttgtacggcaggttggagaaggacagcctcctgaagaaacttgaagaagaa aacgcagaagcggcagaagcggcagaagaaaggcttgcctgttgtaaggacggctgctcg gattctgtaacagggcacaacgaagaggcacctggccacaacggcgagaccaagcccccc aggcccgccggcgtgcggggcggcggtggaagcagagggggcggcagcggcgagctctcg accccggagaagccccccggccagagggcgggcccgttcggcagtcggtgggagacgacc acgggagagcccgccaccagcatcccgaccaccgtcggctcccttcccagttcgaaaagc ttcctgggcaggaaggcgcgagagttatttcgtaataagagcgagagccagtgtgacgag gacagcgtgaccatcagtagcctttctgaaacgctaaagacagaaccgggccaagacccg ggtgcggaaggcaaggcccccccgagcctagacggcccgcacccctcgcccccgaccccg gacagtgttggacagctgcacatcatggactacaacgagactcatcatgaacacagcgaa ggatga

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