Panthera pardus (leopard): 109251797 Help Entry 109251797         CDS       T06062                                  Symbol NF1 Name (RefSeq) neurofibromin   KO K08052   neurofibromin 1 Organism ppad  Panthera pardus (leopard) Pathway ppad01521   EGFR tyrosine kinase inhibitor resistance ppad04010   MAPK signaling pathway ppad04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:ppad00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109251797 (NF1)    04014 Ras signaling pathway     109251797 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     109251797 (NF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  109251797 NCBI-ProteinID:  XP_019279232 Ensembl:  ENSPPRG00000010982 LinkDB All DBs Position Unknown AA seq 2861 aa AA seqDB search MTFSQISLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGE AAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAE LRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRL LKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLV DGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFLDSLRKALAGHGGS RQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADV DLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVY CHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLL LSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLH QLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLK NKQADRSSCHFLFLYGVGCDVPSSGATSQMSMDHEELIRTCTPGASLRKGKGNSSMDSAA GCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNF LPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLI LNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVC LQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLSLMVCNHEKVGL QIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQFVEQTIAIMKNL LDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSF CQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGD GVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSN LLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVEL VTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSM QTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEQSES LEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKS VVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIAN HVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLL WNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEE FMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTL KPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTK YHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDT KVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLT FMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRS AAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECI SGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPS IQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVI GRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLV ATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVK SAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTE LAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLI EATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIF NDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVR ILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENV PMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAATYPAVGQTSPRARKSMSLDMGQPSQ ANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSSQQHP HLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFP KVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGL WRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTSPYPPAVQSQLS ITANLNLSNSMTSLATSQHSPEDSVSPSVIPRPASASFGSSLECRCYSPTADLLRIDKEN VELSPTSGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV NT seq 8586 nt NT seq  +upstreamnt  +downstreamnt atgacgtttagccagatatctcttccaataaaaacaggacagcagaacacgcataccaaa gtcagtactgaacacaacaaggaatgtcttattaatatttccaaatacaagttttctttg gttatcagcggcctcaccactatcttaaagaatgttaacaatatgagaatatttggagaa gctgctgaaaaaaatttatatctctctcagttgattatattggatacactggaaaaatgt cttgctgggcaaccaaaggacacaatgcgattagatgaaacgatgctggtcaaacagttg ctgccagaaatctgccattttcttcacacctgtcgtgaaggaaaccaacatgcagctgaa cttcggaattctgcatctggggttttattttctctcagctgcaacaacttcaacgcagtg tttagtcgcatctctaccaggttacaggaattgactgtttgttcagaagacaatgttgat gttcatgatatagaattgttacagtatatcaatgtggattgtgcaaaattaaaacgactc ctaaaggaaacagcatttaaatttaaagccctaaagaaggttgcacagttagcagttata aatagcctggaaaaagcattttggaactgggtagaaaattatccagatgaatttacaaag ctgtaccagattccacagactgatatggctgagtgtgcagaaaaactgtttgacttggtg gatggttttgccgaaagcaccaagcgtaaagcagcggtttggccactgcaaatcattctc cttatcttgtgtccagaaatcattcaggatatctccaaggatgtggttgatgaaaacaac atgaataagaagttgtttctggacagcctacggaaagcacttgccggccatggaggaagc aggcagctgacggagagtgctgcaatagcctgtgtcaaactgtgcaaagcaagtacttat atcaactgggaagacaactctgtcattttcctcctagtccagtccatggtggttgatctt aagaacctgctttttaatccaagtaagccattctcaagaggcagtcagcccgcagatgtg gatctgatgattgactgccttgtctcttgctttcgtataagccctcacaacaaccaacac tttaagatctgcctggctcagaattccccttctacatttcactatgtgctggtaaattca ctccatcgaatcatcaccaattctgcgttggattggtggcctaagatcgatgctgtatat tgtcactcagtcgagcttcgaaacatgtttggtgaaacgcttcataaagcagtgcagggt tgtggagcacacccagcaatacgaatggcaccgagtcttacatttaaagaaaaagtaaca agccttaaatttaaagaaaaacctacagacctggagacaagaagctataagtatcttctc ctgtccatggtgaaactcattcatgcggatccaaagctcttgctttgtaatccaaggaaa caggggcctgaaacccaaggcagtacagcggaattaattacagggctcgtccagctggtc cctcagtcacacatgccagagatcgcacaggaggcaatggaggctctgctggttcttcat cagttagatagcattgatttgtggaatcctgatgctcctgtggaaacattttgggaaatt agctctcaaatgcttttttacatctgcaagaaattaactagccatcaaatgcttagtagc acagaaattctcaaatggttgcgggaaattttgatctgcaggaataaatttcttcttaaa aataagcaggcagatagaagttcctgtcactttctcttcctttacggggtaggatgtgat gttccttcgagtggagctaccagtcagatgtccatggatcatgaagaattaatacgtact tgtacgcctggagcctctcttcggaagggaaaaggaaactcatccatggatagtgcagca gggtgcagcggcacaccgccgatatgccgacaggctcagaccaaactcgaagtggccctg tacatgtttctgtggagccctgacactgaagctgttctggttgccatgtcctgcttccgc cacctctgtgaggaggcagatatccggtgtggggtggatgaagtgtcggtgcacaacttc ttgcccaactataacacattcatggaatttgcctctgtcagcaatatgatgtcaacagga agagcagcacttcagaaaagagtgatggcactactcaggcgcatcgagcaccccactgca ggaaacacggaggcttgggaagatacacatgcaaagtgggaacaagccacaaaactaatc ctcaactatccaaaagctaaaatggaagatggccaggctgctgaaagccttcacaagacc attgttaagaggcgaatgtctcatgtgagtggaggaggatccatagatttgtctgacacg gactccctacaggaatggatcaacatgactggcttcctttgcgcccttgggggagtgtgc ctgcagcaaagaagcaactctggcttggcaacctatagcccccctatgggcccagtcagt gaacgcaagggttccatgatttcggtgatgtcctcggagggaaatgcagatacacctgtc agcaaatttatggatcggctgttatccttaatggtgtgtaaccatgagaaagtgggactt caaatacggaccaacgttaaggatctggtgggtctagaattgagtcctgctctttatcca atgctatttaacaaattgaagaataccatcagcaagttttttgactcgcaaggacaggtt ttattgaccgacaccaatactcagtttgtggagcaaaccatagctataatgaagaactta ctagataatcataccgaaggcagctccgaacatctggggcaagctagcattgaaacaatg atgttaaatctagtcagatatgttcgagtgcttgggaacatggtccatgcaattcaaata aaaacgaagctgtgtcagttagtcgaggtaatgatggcaaggagagatgacctctcattt tgtcaagagatgaaatttaggaataaaatggtagaatacctgacagactgggtcatggga acatcaaaccaagcagcagatgatgatgtaaaatgtcttacaagagacttggaccaggcg agcatggaagccgttgtctcactcctggctggtcttccactgcagcctgaggaaggagat ggtgtggaattgatggaagccaagtcacagttatttctgaagtatttcacattgtttatg aaccttttgaatgactgtagtgaagttgaagatgaaaatgcacaaacaggtggcaggaaa cgtggcatgtcccggaggctggcatcactgaggcactgcacagtccttgcaatgtccaac ttactcaatgctaacgtggacagtggcctcatgcactccataggtttaggttatcacaaa gatcttcagacaagagctacatttatggaagttctgacaaaaatcctccagcaaggcaca gaatttgacacgcttgcagaaacggtgctggccgaccggtttgagaggctggtggagttg gtcacaatgatgggagaccagggagagctcccaatagccatggctttggccaacgtggtc ccgtgttctcagtgggatgaactagctcgagttctagtgactctgtttgattctcggcat ttgctctaccaactgctctggaacatgttttctaaggaagtagaattggcagactccatg cagactcttttccgaggaaacagcttagccagtaaaataatgaccttctgtttcaaggta tatggtgctacctacctacaaaaactcctggatccgttattacgaatcgtgatcacatcc tctgactggcaacatgttagctttgaagtggatcctaccaggttagaacaatcagagagc cttgaggaaaaccaacggaaccttctgcagatgactgaaaagttcttccatgccatcatc agttcctcctcagaattcccccctcagcttcgaagtgtgtgccactgtttataccaggca acttgccactccctactgaataaagctacagtaaaagaaaaaaaggaaaacaaaaaatca gtggttagccagcgtttccctcagaacagcatcggtgcggtgggaagtgccatgttcctc agatttatcaatcctgccattgtctcaccgtatgaagcagggattttagataaaaagccg ccacctagaattgaaaggggcttgaagttaatgtcaaagatacttcagagcattgccaat catgttctcttcacaaaagaagagcatatgcggccttttaatgattttgtgaaaagcaac tttgatgcagcgcggaggtttttccttgatatagcatctgattgtcctaccagtgatgca gtaaatcatagtctctccttcatcagtgatggcaatgtgcttgctttacatcgtctactc tggaacaatcaagagaaaattggccagtatctttccagtaacagggatcacaaagctgtt ggaagacgaccttttgataagatggcaacacttcttgcgtacttgggtcctccagagcac aaacctgtggccgatacacattggtccagccttaaccttaccagttcaaagtttgaggaa tttatgactaggcatcaagtacatgaaaaagaagagttcaaggctttgaaaacattaagt attttctaccaagctgggacttccaaagctgggaatcctatattttattatgttgcacgg aggtttaaaactggccaaatcaatggcgatttgctgatataccacgtcttgctgacttta aagccatattatgcaaagccatatgaaattgtagtggaccttacccataccgggcctagc aatcgctttaaaacagactttctctccaagtggtttgttgtttttcctggctttgcttat gacaatgtctctgcagtctatatctataactgcaactcctgggtcagagagtataccaag tatcacgaacggctactgactggcctcaaaggcagcaagaggctcattttcatcgactgt cctggcaaactggctgagcacatagagcatgaacaacagaaactgcctgctgccacactg gctttagaagaggacctgaaggtattccacaatgctctcaagctagctcacaaagacacc aaggtttctattaaagttggttctactgctgttcaagtaacctcagcagagcgaacaaaa gtcctaggacagtcggtctttctaaatgatatctattatgcttcggaaattgaagagatc tgcctggtggatgagaaccagtttaccttaaccattgcaaaccagggcacaccgctcacc ttcatgcaccaggagtgcgaagccatcgtccagtctatcattcacatccggacacgctgg gagctgtcgcagcccgactccatcccccagcacaccaagattcggccaaaagatgtccct gggacactactcaatattgcattacttaatttaggcagttccgaccctagtttacggtca gctgcctataatcttctctgtgccttaacttgtacctttaatttaaaaatcgagggccag ctactagagacatcaggtttatgcatccctgccaacaacaccctctttattgtctctatt agtaagacactggcggccaatgagccacatctcaccttagaatttttggaagagtgtatt tctggatttagcaaatctagtattgaattgaaacacctttgtttggaatacatgactcca tggctgtcaaacctagtccgtttttgtaagcacaatgatgatgccaaacgacaaagagtt accgccattctcgataagctgataacaatgaccataaatgagaaacagatgtacccatct attcaagccaaaatatgggggagccttgggcagattacagatctccttgacgttgtacta gacagtttcatcaaaaccagtgcgacaggtggcttgggatcaataaaagccgaggtgatg gcagatactgccgtagctttggcttctggaaatgtgaaattggtttccagcaaggttatt ggaaggatgtgcaaaataattgacaagacatgcttgtctccaactcctaccttagagcag catctcatgtgggacgacattgccatcctcgcacgctacatgctgatgctgtccttcaac aattcccttgacgtggcagctcatctcccctacctcttccacgttgttactttcttagta gccacggggccgctctcccttagagcttccacacacggattggtcattaatatcattcac tctctgtgtacttgttcacagctgcattttagtgaagagaccaagcaagttttgagactc agtttgacagagttctcgttacccaagttttacttgctgtttggcattagcaaagtcaag tcagctgccgtcattgccttccgctccagttaccgggacaggtcgttctctcctggctcc tatgagagggagacttttgctttgacatccttggaaacagtcacagaggctttgttggag ataatggaggcatgtatgagagatattccaacatgcaagtggctggaccagtggacggaa ctagctcaaagattcgcattccaatataatccatccctgcaaccgagagctcttgttgtc tttggctgtattagcaagcgagtgtctcatgggcagataaagcagattatccgtattctt agcaaggcacttgagagttgcttaaaaggacctgatacttacaacagtcaagttctgata gaagccacagtaatagcgctaaccaaattacagccgctcctcaataaggactcccctctg cacaaagccctcttttgggtagctgtggctgtgctacagctcgatgaggtcaacttgtat tcagcaggcaccgcacttcttgaacaaaacctgcacaccttagacagtctgcggatattc aacgacaagagtccagaggaagtatttatggcaatccggaaccctctggaatggcactgc aagcagatggatcattttgttggactcaatttcaactctaactttaacttcgcgctggtt ggacacctcttaaaagggtacaggcatccttcacctgccattgttgcaagaacggtcaga attctgcatacactactgactctggtcaacaaacatagaaactgtgacaaatttgaggtg aacacacagagcgtggcttacttggcagccttactcacagtgtctgaggaggttcgaagt cgctgtagcctaaaacatagaaagtctcttcttcttactgatatttcaatggaaaatgtt cctatggatacatatcccatccatcatggcgaccccagctataggacgctaaaggagaac cagccgtggtcatctcccaaaggttctgaggggtaccttgcagccacctatccagccgtg ggccagaccagtccccgggccaggaagtccatgagcttggacatggggcagccttctcag gccaacacgaagaagttgctgggaacaaggaaaagttttgatcacttgatatcagacaca aaggctcctaaaaggcaagaaatggaatcagggatcacaacaccccccaaaatgaggaga gtagcagaaactgattatgaaatggaaactcagaggatttcctcatcacaacaacacccg catttgcgtaaagtttcggtgtctgaatcaaatgttctcttggatgaagaagtacttact gatccaaagatccaagcacttcttcttaccgttctggctacgctggtaaaatataccacg gatgagtttgatcagcgaatcctttatgaatacttagcggaagccagtgttgttttcccc aaggtttttccagtcgtacacaatttgttggactctaagatcaacaccctattgtcattg tgccaagatccaaatttgttaaatccaattcatggaattgtgcagagtgtggtgtaccat gaagaatctccaccacagtaccagacatcatacctgcaaagttttggttttaatggcttg tggcggtttgcaggacccttttcaaagcaaacccaaatcccagactatgctgagcttatt gttaagtttcttgatgccttgattgacacgtatttgcctggaattgatgaagaaaccagt gaggagtccctcctgacacccacttctccttatcctcctgcagtgcagagccagcttagt atcactgctaaccttaacctttctaattccatgacctcactcgcaacttcccagcattcc ccagaggacagtgtttctccaagtgtgattcctagaccagcatcagcgtcatttgggagc tcgctagaatgcaggtgctacagtcccactgcagacctcctgcggatcgacaaggagaac gttgaactctcccccacctctggccactgtaacagtggacgcactcgccatggatccgca agccaggtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcattaagaagatc gtgtga

DBGET integrated database retrieval system