Panthera pardus (leopard): 109251875
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Entry
109251875 CDS
T06062
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform X1
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00220
Arginine biosynthesis
ppad00330
Arginine and proline metabolism
ppad01100
Metabolic pathways
ppad04020
Calcium signaling pathway
ppad04066
HIF-1 signaling pathway
ppad04146
Peroxisome
ppad04371
Apelin signaling pathway
ppad04926
Relaxin signaling pathway
ppad05010
Alzheimer disease
ppad05014
Amyotrophic lateral sclerosis
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05133
Pertussis
ppad05140
Leishmaniasis
ppad05142
Chagas disease
ppad05145
Toxoplasmosis
ppad05146
Amoebiasis
ppad05152
Tuberculosis
ppad05200
Pathways in cancer
ppad05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
109251875 (NOS2)
00330 Arginine and proline metabolism
109251875 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
109251875 (NOS2)
04066 HIF-1 signaling pathway
109251875 (NOS2)
04020 Calcium signaling pathway
109251875 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
109251875 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
109251875 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109251875 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
109251875 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
109251875 (NOS2)
05152 Tuberculosis
109251875 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
109251875 (NOS2)
05145 Toxoplasmosis
109251875 (NOS2)
05140 Leishmaniasis
109251875 (NOS2)
05142 Chagas disease
109251875 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
109251875 (NOS2)
05014 Amyotrophic lateral sclerosis
109251875 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
109251875 (NOS2)
Enzymes [BR:
ppad01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
109251875 (NOS2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
109251875
NCBI-ProteinID:
XP_019279369
Ensembl:
ENSPPRG00000003356
UniProt:
A0A9V1EDH1
LinkDB
All DBs
Position
Unknown
AA seq
1157 aa
AA seq
DB search
MACPWQFLFKAKSHQYNLTEETDINNNVGKAVWAPSGLVTQDDPKCHSLSKHRNEPPQSL
TGTVKTVPESLGKLDMPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACRSKSCLGAIM
NPKSLTRGPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNI
RSAITVFPQRSDGKHDFRIWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYG
RFDVVPLVLQADGGDPELFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFFYYQVEAWKTHIWQDEKRRPRRRKIPFKVLVQAVLFASMLMRKTMASRVRAT
ILFATETGKSETLARDLGALFSCAFNPKILCMDQYRLSNLEEEQLLLVVTSTFGNGDSPG
NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACETFDVRGKHRIQIPKLYTSNVTWDPHHYRLVQDSQPLDL
NKALGSMHAKNVFTMRLKSQRNLQSAKSSRTTLLVELSCEDSHRLSYLPGEHLGVFPGNQ
LALVKGILERVVDGPAPHQPVHLETLSESGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ
LLLRKLAQLATEEAERQRLEILCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL
PILKPRYYSISSSRACAPTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF
VRSAGGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDAEHKGLRGSRMTLVFGCRRPD
EDHLYREEMLEMAQKGVLHEVHTAYSRLPGQPKVYVQDILRQQLASEVLRVLHEEQGHLY
VCGDVRMARDVAQTLKHLLATKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDG
AARQPSDPRVPAAHGTS
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccctggcagtttctgttcaaggccaaatcccaccagtacaacttgactgag
gaaacagacatcaacaacaatgtggggaaggccgtctgggccccctctggtctagtgaca
caggatgaccccaagtgtcacagcctcagcaaacaccggaatgagcccccccagtccctc
acggggacagtaaagacagttccagaatccctggggaagctggatatgcccccgtcggcc
tgcccacggcacgtgaggatcaaaaactggggcagtgggatgactttccaagacacactt
caccacaaggccaaaggggatcttgcttgcaggtctaagtcttgtctgggagccatcatg
aaccccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagcttcta
cctcaagctatcgaatttgtcaaccagtattacagctccttcaaagaagcaaaaatagag
gaacatctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctatcag
ctgacgggagatgagctcatcttcgccaccaagcaggcttggcgcaatgccccccgctgc
atcgggaggatccagtggtccaacctacaggtcttcgatgcccggagctgttccactgcc
caggaaatgtttgagcacatctgcagacacgtgcgttatgctaccaacaatggcaacatc
aggtcggccatcaccgtgttcccccagcggagtgatgggaagcatgacttccggatctgg
aacgctcagctcatccggtatgctggctaccagatgcctgatggcaccatcctgggggac
cctgccagcgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacggc
cgctttgatgtggtgcctctggtcctgcaggctgatggcggagaccctgagctctttgaa
atcccgcctgacctcgtgctcgaggtgcccatggaacatcccaagtatgagtggttccgt
gaactggagctaaagtggtatgccctgcctgccgtggccaacatgctgctcgaggtgggt
ggcctggagttcccagggtgccccttcaatggctggtacatgggcacggagatcggggtc
cgggacttctgtgacgttcagcgctacaacatcctggaggaagtgggcagaaggatgggc
ctggaaacacacaaactggcctcactctggaaggaccgggctgtcattgagatcaacgtc
gccgtgctgcacagtttccagaagcaaaacgtgaccatcatggaccaccactcggctgcg
gagtccttcatgaagtacatgcagaacgagtaccggtcccgagggggctgtcctgccgac
tggatttggctggtgcccccaatttctggcagcatcactcccgtgttccaccaggagatg
ttaaactatgtcctgtcccctttcttctactaccaggtggaggcctggaaaacccacatc
tggcaggatgagaagcggagaccccggagaagaaagattccgttcaaagtcttggttcaa
gctgtgctcttcgcctccatgctgatgcgcaagaccatggcgtcccgagtgagagccaca
atcctctttgcgacggagacaggaaagtcagaaacactggcccgggacctaggggccttg
ttcagctgtgccttcaaccccaagattctctgcatggaccagtacaggctgagcaacctg
gaggaagagcagctactactggtggtgaccagcacgtttgggaacggagactcccccggc
aacggagagaaactgaaaaaatccctcttcatgctgaaagagcttaccaacaagttcagg
tatgccgtgttcggcctcggctccagtatgtaccctcggttctgtgcctttgctcatgac
atcgaccagaagctgtcccatctgggggcctctcagcttgccccaacaggggaaggggac
gagctcagtggacaggaggaagccttccgcagctgggccgtgcaaaccttcaaggcagcc
tgtgagacgttcgatgtgcgaggcaagcaccgcattcagatccccaagctctacacctcc
aatgtgacctgggacccgcaccactacaggctcgtgcaggactcacagcctctggacctc
aacaaagctctcggcagtatgcacgccaagaacgtgttcaccatgaggctcaaatcacag
cggaatctccagagtgcgaaatccagccgcaccaccctcctggtggagctctcctgtgag
gacagccaccggctgagctacctgcctggagagcacctcggggttttcccaggcaaccag
ctggctctggtaaaaggcatcttggagcgagtggtggacggccctgcaccccaccaaccg
gtgcacctggagaccctcagcgagagcggaagctactgggtcagagacaagcggctgccc
ccgtgctcgctcagccaggccctcacctacttcctggatatcaccacccccccaacccag
ctgctgctccgcaaattggcacagctggccacagaagaggcagagaggcagaggctggag
atcctgtgccagccctcagagtacaacaaatggaagttcaccaatagccccacattcctg
gaggtactggaggagttcccatccctgcgggtgtctgctggcttcctgctctcccagctg
cctattctgaaaccccggtactactccatcagctcctccagggcctgtgcacccacggag
gtccacctcactgtggctgtgctcacctaccgcacccgagatggccaaggtcccttgcac
cacggcgtctgcagcacatggctcagcagcctgaagccccaagacccagtaccctgcttt
gtgagaagtgccggcggcttccagctccctgaggacccttcccaaccttgcatcctcatt
gggcctggcacaggcatcgcccccttccgcagcttctggcagcagcggctccatgatgcc
gagcacaaagggctccggggcagccgcatgaccctggtgttcgggtgccgccgcccggat
gaggaccacctctatcgggaggagatgttggagatggcccagaagggggtgctgcatgag
gttcacacagcctactctcgcctgcctggccagcccaaggtctatgttcaagacatcctg
aggcagcagctggccagcgaggtgctccgtgtgctccatgaggagcaaggccacctttat
gtctgtggggatgtgcgtatggcccgggatgtggcccaaaccctgaagcacctcctggcc
accaagctgagcctgagcgaggagcaggtggaggactatttcttccaacttaagagccag
aagcgctatcatgaagacatctttggtgctgtatttccctacgaggtgaaaaaggatggg
gcagcaaggcagcccagcgatcccagagttccagcggcccacgggacaagttaa
DBGET
integrated database retrieval system
