KEGG   Panthera pardus (leopard): 109253991
Entry
109253991         CDS       T06062                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad01522  Endocrine resistance
ppad04010  MAPK signaling pathway
ppad04014  Ras signaling pathway
ppad04020  Calcium signaling pathway
ppad04024  cAMP signaling pathway
ppad04062  Chemokine signaling pathway
ppad04081  Hormone signaling
ppad04082  Neuroactive ligand signaling
ppad04114  Oocyte meiosis
ppad04140  Autophagy - animal
ppad04211  Longevity regulating pathway
ppad04213  Longevity regulating pathway - multiple species
ppad04261  Adrenergic signaling in cardiomyocytes
ppad04270  Vascular smooth muscle contraction
ppad04310  Wnt signaling pathway
ppad04340  Hedgehog signaling pathway
ppad04371  Apelin signaling pathway
ppad04530  Tight junction
ppad04540  Gap junction
ppad04611  Platelet activation
ppad04713  Circadian entrainment
ppad04714  Thermogenesis
ppad04720  Long-term potentiation
ppad04723  Retrograde endocannabinoid signaling
ppad04724  Glutamatergic synapse
ppad04725  Cholinergic synapse
ppad04726  Serotonergic synapse
ppad04727  GABAergic synapse
ppad04728  Dopaminergic synapse
ppad04740  Olfactory transduction
ppad04742  Taste transduction
ppad04750  Inflammatory mediator regulation of TRP channels
ppad04910  Insulin signaling pathway
ppad04911  Insulin secretion
ppad04912  GnRH signaling pathway
ppad04913  Ovarian steroidogenesis
ppad04914  Progesterone-mediated oocyte maturation
ppad04915  Estrogen signaling pathway
ppad04916  Melanogenesis
ppad04918  Thyroid hormone synthesis
ppad04919  Thyroid hormone signaling pathway
ppad04921  Oxytocin signaling pathway
ppad04922  Glucagon signaling pathway
ppad04923  Regulation of lipolysis in adipocytes
ppad04924  Renin secretion
ppad04925  Aldosterone synthesis and secretion
ppad04926  Relaxin signaling pathway
ppad04927  Cortisol synthesis and secretion
ppad04928  Parathyroid hormone synthesis, secretion and action
ppad04934  Cushing syndrome
ppad04935  Growth hormone synthesis, secretion and action
ppad04961  Endocrine and other factor-regulated calcium reabsorption
ppad04962  Vasopressin-regulated water reabsorption
ppad04970  Salivary secretion
ppad04971  Gastric acid secretion
ppad04976  Bile secretion
ppad05012  Parkinson disease
ppad05020  Prion disease
ppad05030  Cocaine addiction
ppad05031  Amphetamine addiction
ppad05032  Morphine addiction
ppad05034  Alcoholism
ppad05146  Amoebiasis
ppad05163  Human cytomegalovirus infection
ppad05165  Human papillomavirus infection
ppad05166  Human T-cell leukemia virus 1 infection
ppad05200  Pathways in cancer
ppad05203  Viral carcinogenesis
ppad05205  Proteoglycans in cancer
ppad05207  Chemical carcinogenesis - receptor activation
ppad05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109253991 (PRKACA)
   04014 Ras signaling pathway
    109253991 (PRKACA)
   04310 Wnt signaling pathway
    109253991 (PRKACA)
   04340 Hedgehog signaling pathway
    109253991 (PRKACA)
   04371 Apelin signaling pathway
    109253991 (PRKACA)
   04020 Calcium signaling pathway
    109253991 (PRKACA)
   04024 cAMP signaling pathway
    109253991 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    109253991 (PRKACA)
   04081 Hormone signaling
    109253991 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109253991 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    109253991 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    109253991 (PRKACA)
   04540 Gap junction
    109253991 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109253991 (PRKACA)
   04062 Chemokine signaling pathway
    109253991 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    109253991 (PRKACA)
   04910 Insulin signaling pathway
    109253991 (PRKACA)
   04922 Glucagon signaling pathway
    109253991 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    109253991 (PRKACA)
   04912 GnRH signaling pathway
    109253991 (PRKACA)
   04913 Ovarian steroidogenesis
    109253991 (PRKACA)
   04915 Estrogen signaling pathway
    109253991 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    109253991 (PRKACA)
   04921 Oxytocin signaling pathway
    109253991 (PRKACA)
   04926 Relaxin signaling pathway
    109253991 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    109253991 (PRKACA)
   04918 Thyroid hormone synthesis
    109253991 (PRKACA)
   04919 Thyroid hormone signaling pathway
    109253991 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    109253991 (PRKACA)
   04916 Melanogenesis
    109253991 (PRKACA)
   04924 Renin secretion
    109253991 (PRKACA)
   04925 Aldosterone synthesis and secretion
    109253991 (PRKACA)
   04927 Cortisol synthesis and secretion
    109253991 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    109253991 (PRKACA)
   04270 Vascular smooth muscle contraction
    109253991 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    109253991 (PRKACA)
   04971 Gastric acid secretion
    109253991 (PRKACA)
   04976 Bile secretion
    109253991 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    109253991 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    109253991 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    109253991 (PRKACA)
   04727 GABAergic synapse
    109253991 (PRKACA)
   04725 Cholinergic synapse
    109253991 (PRKACA)
   04728 Dopaminergic synapse
    109253991 (PRKACA)
   04726 Serotonergic synapse
    109253991 (PRKACA)
   04720 Long-term potentiation
    109253991 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    109253991 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    109253991 (PRKACA)
   04742 Taste transduction
    109253991 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    109253991 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    109253991 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    109253991 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    109253991 (PRKACA)
   04714 Thermogenesis
    109253991 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109253991 (PRKACA)
   05205 Proteoglycans in cancer
    109253991 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    109253991 (PRKACA)
   05203 Viral carcinogenesis
    109253991 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109253991 (PRKACA)
   05163 Human cytomegalovirus infection
    109253991 (PRKACA)
   05165 Human papillomavirus infection
    109253991 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109253991 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    109253991 (PRKACA)
   05020 Prion disease
    109253991 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    109253991 (PRKACA)
   05031 Amphetamine addiction
    109253991 (PRKACA)
   05032 Morphine addiction
    109253991 (PRKACA)
   05034 Alcoholism
    109253991 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    109253991 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    109253991 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    109253991 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109253991 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:ppad03019]
    109253991 (PRKACA)
   03036 Chromosome and associated proteins [BR:ppad03036]
    109253991 (PRKACA)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     109253991 (PRKACA)
Protein kinases [BR:ppad01001]
 Serine/threonine kinases: AGC group
  PKA family
   109253991 (PRKACA)
Messenger RNA biogenesis [BR:ppad03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     109253991 (PRKACA)
Chromosome and associated proteins [BR:ppad03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    109253991 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 109253991
NCBI-ProteinID: XP_019283016
Ensembl: ENSPPRG00000023771
UniProt: A0A9W2V374
LinkDB
Position
Unknown
AA seq 360 aa
MGPSSLYPSPPFPLHPLLEEVGSRVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLG
TGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSF
KDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPE
NLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYE
MAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND
IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgggtcccagctcactctatccctctccacccttcccattgcaccctctgctggaagag
gtaggaagcagagtgaaagagttcttagccaaagccaaagaagattttcttaaaaaatgg
gaaaatcctgctcagaatacagcccatttggatcagtttgaacgaatcaagaccctcggc
acgggctcctttgggcgggtgatgctggtaaagcacaaggagaccgggaaccactttgcc
atgaagatcctcgacaaacagaaggtggtgaagctgaaacagattgagcacaccctgaat
gaaaagcgcatcctgcaagcggtcaactttccgttcctcgtcaaactcgagttctccttc
aaggacaactcgaacttatacatggtcatggagtacgtgcctggcggggagatgttctca
cacctgcggcggattggaaggttcagtgaacctcacgcgcgcttttatgcggcccagatc
gtcctgaccttcgagtacctgcactcacttgacctcatctaccgggacctgaagccggag
aacctcctcattgaccagcagggctacattcaggtgacagacttcggttttgccaagcgt
gtaaaaggccgcacctggaccttatgcgggacccctgagtacctggccccggagatcatc
ctgagcaaaggctacaacaaggccgtggactggtgggccctaggggttctcatctacgag
atggccgctggctacccgcctttcttcgctgaccagcccatccagatctatgagaagatt
gtctctgggaaggtgcggttcccatcccacttcagctccgacctgaaggatctgctgcgg
aacctactgcaggtggacctcaccaaacgctttgggaacctcaagaatggagtcaatgat
atcaagaaccacaaatggtttgccacaactgactggatcgccatctaccagaggaaggtg
gaagctcccttcataccaaagtttaaaggccctggggacacgagtaatttcgacgactat
gaggaggaagagatccgagtctccatcaatgagaagtgtggcaaggagtttactgagttt
tag

DBGET integrated database retrieval system