Panthera pardus (leopard): 109256357
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Entry
109256357 CDS
T06062
Symbol
PKLR
Name
(RefSeq) LOW QUALITY PROTEIN: pyruvate kinase PKLR
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00010
Glycolysis / Gluconeogenesis
ppad00620
Pyruvate metabolism
ppad01100
Metabolic pathways
ppad01200
Carbon metabolism
ppad01230
Biosynthesis of amino acids
ppad04910
Insulin signaling pathway
ppad04930
Type II diabetes mellitus
ppad04932
Non-alcoholic fatty liver disease
ppad04950
Maturity onset diabetes of the young
Module
ppad_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ppad_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
109256357 (PKLR)
00620 Pyruvate metabolism
109256357 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
109256357 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
109256357 (PKLR)
04950 Maturity onset diabetes of the young
109256357 (PKLR)
04932 Non-alcoholic fatty liver disease
109256357 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ppad04147
]
109256357 (PKLR)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
109256357 (PKLR)
Exosome [BR:
ppad04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
109256357 (PKLR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK
PK_C
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
109256357
NCBI-ProteinID:
XP_019287121
Ensembl:
ENSPPRG00000019731
LinkDB
All DBs
Position
Unknown
AA seq
553 aa
AA seq
DB search
MIWGNLFNLPQPLSPSLENGDTCRARNGTRSTGSLELGPAGYLRRVSGAHLARELGTAFF
ERQQLSAAMADTFLEHLCLLDIDSEPVAARSTCIIATIGKQPPPPPSLPDLWPGHSFNRY
LLRLGSQGYHAQSIANIREAVQSFATSPLSYRPVAIALDTKGPEIRTGVLQGVRGAXAXW
VDYPNIVKVVSVGSRIYIDDGLISLQVQKIGPEGLETHVENGGVLGSRKGVNLPGAQVDL
PGLSEQDARDLRFGVEHEVDIVFASFVRKASDVAAIREVLGPEGRNIKIISKIENHEGVK
RFDEILEVSDGIMVARGDLGIEIPPEKVFLAQKMMIGRCNLAGKPVVCATQMLESMIAKP
RPTRAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKMQHAIAREAEAAIYHRQLFEEL
RRVAPLSRDPTEVTAIGAVEASFKCCAAAIVVLSKSGRSAQLLSRYRPRAMVIAVTRSAQ
AARQAHLFRGVFPVLYSKPPEAIWADDVDHRVQFGIESGKLHGFLRVGDLVIVVTGWRPG
SGYTNIMRVLSVS
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgatctggggcaatttatttaatcttcctcaacccctgtctccttctctggaaaatggg
gacacttgtagagcacgtaacggtactcgctccacaggatccttggaactagggccagcc
gggtacctacggcgggtcagcggggcccacctggcccgcgagctgggcaccgccttcttc
gagcggcagcagctgtcggccgccatggcggacaccttcctggagcacctgtgcctgctg
gacatcgactcggagcccgtggccgcccgcagtacctgcatcatcgccaccatcggtaag
caaccccccccaccccccagcctcccggacctctggccgggtcattcattcaacagatac
ttgttgaggcttggtagccaaggttaccacgctcagtccatcgccaacatccgggaggcc
gtgcagagctttgcaacttctccgctcagctaccgacccgtggccatcgctctggacacc
aagggacccgagatacgcaccggggtcctgcagggggtgagaggggcgngggcttgntgg
gtagactaccccaatatcgtcaaggtcgtgtcggtggggagccgtatctacatagacgac
gggctcatctccctccaggtgcagaaaatcggcccggaggggctggagacccacgtggag
aacggcggcgtcctgggcagccgcaagggcgtgaacctgcccggagcccaggtggacctg
ccggggctgtccgagcaggatgcccgggacctgcgcttcggggtggagcatgaggtagac
atcgtgtttgcctcctttgtgcggaaagccagtgacgtggctgccatccgggaagttctg
gggccggaaggacggaacatcaagatcattagcaaaatcgagaaccacgaaggcgtgaag
aggtttgatgagatcctggaggtgagcgacggcatcatggtggctcgaggagacctgggc
atcgagatcccacctgagaaggttttcctggctcagaagatgatgatcggacgctgcaac
ctggcgggcaagcctgttgtgtgtgccacgcagatgctggagagcatgatcgccaagccc
cggccgactcgggcagagacgagcgacgtggcaaacgccgtgctggacggggcggactgc
atcatgctgtcgggggagaccgccaagggcaaatttcccgtggaggcagtaaagatgcag
cacgcgatcgcccgggaggccgaggctgccatctaccaccgacagctgtttgaggagctg
cgccgggtggcgcccctgagccgggatcccactgaggtcactgccatcggcgcggtggag
gcctccttcaagtgctgtgctgctgccattgtcgtgctgagcaagtctggccgctcggca
cagctgctgtctcggtaccgacctcgggcaatggtcattgccgtcacccgctctgcccag
gctgcccggcaggcccacctgttccgaggggtcttccccgtgctctacagtaaacctcca
gaggccatctgggcagacgacgtggatcaccgggtccaatttggcattgagagtggaaag
ctccatggcttcctccgtgttggggacctggtgattgtggtgacaggctggcgacctggc
tctggctacaccaacatcatgcgggtgctgagtgtgtcctga
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