KEGG   Panthera pardus (leopard): 109256413
Entry
109256413         CDS       T06062                                 
Symbol
ESR1
Name
(RefSeq) estrogen receptor isoform X1
  KO
K08550  estrogen receptor alpha
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad01522  Endocrine resistance
ppad04081  Hormone signaling
ppad04915  Estrogen signaling pathway
ppad04917  Prolactin signaling pathway
ppad04919  Thyroid hormone signaling pathway
ppad04961  Endocrine and other factor-regulated calcium reabsorption
ppad05200  Pathways in cancer
ppad05205  Proteoglycans in cancer
ppad05207  Chemical carcinogenesis - receptor activation
ppad05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109256413 (ESR1)
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    109256413 (ESR1)
   04917 Prolactin signaling pathway
    109256413 (ESR1)
   04919 Thyroid hormone signaling pathway
    109256413 (ESR1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    109256413 (ESR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109256413 (ESR1)
   05205 Proteoglycans in cancer
    109256413 (ESR1)
   05207 Chemical carcinogenesis - receptor activation
    109256413 (ESR1)
  09162 Cancer: specific types
   05224 Breast cancer
    109256413 (ESR1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    109256413 (ESR1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ppad03000]
    109256413 (ESR1)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:ppad03310]
    109256413 (ESR1)
Transcription factors [BR:ppad03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen receptor-like
    109256413 (ESR1)
Nuclear receptors [BR:ppad03310]
 3. Estrogen like
  3A. Estrogen receptor
   109256413 (ESR1)
SSDB
Motif
Pfam: Oest_recep zf-C4 Hormone_recep ESR1_C
Other DBs
NCBI-GeneID: 109256413
NCBI-ProteinID: XP_019287275
Ensembl: ENSPPRG00000009745
UniProt: A0A9V1ERU0
LinkDB
Position
Unknown
AA seq 595 aa
MTMTLHTKASGMALLHQIQGNELETLNRPQLKIPLERPLGEVYVDGSKPAVYSYPEGAAY
DFNAAPAASAPVYGQSGLAYGSGSEAAAFGANGLGGFPPLNSVSPSPLVLLHPPPQLSPF
LHPHGQQVPYYLENEPSGYAVREAGPPAFYRPNSDNRRQSGRERLASTGDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDEGEGRNEVGSSGDVRASNLWPSPLLIKH
TKKNSPALSLTADQMVSALLEAEPPIIYSDYDPSRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLSLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLL
LEMLDAHRLHAPANRGGAPMEEMNQSQLATTGSTSAHSLQAYYITEEAGAFPTTV
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgaccatgaccctccacaccaaagcgtctggaatggccctgctgcatcaaatccaaggg
aacgagctggagaccctgaaccgcccgcagctcaagatccccctggagcggcccctgggc
gaggtgtacgtggacggcagcaagcccgccgtgtacagctatcccgagggcgccgcgtac
gacttcaacgccgcgcccgccgcctccgcgccggtctacggccagtcgggcctcgcctat
ggctccgggtccgaggcggcggcgttcggcgccaacggcctggggggcttcccgccgctc
aacagcgtgtctccgagcccgctggtgctgctgcacccgccgccgcagctctcgcccttc
ctgcacccccacggccagcaggtgccctattacctggagaacgagccgagcggctacgcc
gtgcgcgaggccggtcctcccgcgttctacaggccaaattcagataatcggcgccagagt
ggcagagagagattggccagtactggtgataagggaagcatggccatggagtctgccaag
gagacccgctactgtgcagtatgcaatgactatgcctcaggctaccattatggagtatgg
tcctgtgagggctgtaaggccttcttcaagagaagtattcaaggacataatgactacatg
tgtccagctaccaaccagtgcacgatcgataagaacaggaggaagagttgtcaggcctgc
cggctccggaagtgctatgaagtaggcatgatgaaaggcggaatacggaaagaccgaaga
ggaggaagaatgttgaaacacaagcgccagagagatgagggggagggcaggaatgaagtg
gggtcttccggagatgtgagggcttccaacctttggccaagccctctcttgattaagcat
actaagaagaacagcccagccttgtccctgacagccgatcagatggtcagtgccttgttg
gaggctgagccccccataatctattccgactacgatccttccagacccttcagtgaggct
tcgatgatgggcttgctgaccaaccttgctgacagggagctggttcacatgatcaactgg
gcaaagagggtgccaggctttgttgatttgagcctccacgatcaggttcaccttctggaa
tgtgcctggctagagatcctgatgattggacttgtctggcgctccatggagcatccaggg
aagctcctatttgctcccaacttgctcctggacaggaaccagggaaaatgtgtagagggg
atggtggagatctttgacatgttgctggctacgtcatctcgatttcgcatgatgaatctc
cagggagaggagttcgtgtgtctcaaatccatcattttgcttaattctggagtgtacaca
tttctgtccagcaccctgaagtctctggaagagaaggaccatatccatcgtgtcttggac
aagatcacagacaccttgatccacctgatggccaaagcgggcctgactctgcagcagcag
caccggcgtctggcccagctcctcctcatcctgtcccacatcaggcacatgagtaacaaa
ggcatggagcacctgtacaacatgaagtgcaaaaacgtagtgcctctctatgacctgctg
ttggagatgctggacgcccaccgcctgcacgccccagccaaccgggggggcgcacccatg
gaggagatgaaccagagccagctggccaccacgggctcaacttcagcacattccttgcaa
gcatattacatcaccgaggaggcgggggctttccccaccacagtctga

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