Panthera pardus (leopard): 109257221
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Entry
109257221 CDS
T06062
Symbol
ATP1A2
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-2
KO
K01539
sodium/potassium-transporting ATPase subunit alpha [EC:
7.2.2.13
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04022
cGMP-PKG signaling pathway
ppad04024
cAMP signaling pathway
ppad04260
Cardiac muscle contraction
ppad04261
Adrenergic signaling in cardiomyocytes
ppad04820
Cytoskeleton in muscle cells
ppad04911
Insulin secretion
ppad04918
Thyroid hormone synthesis
ppad04919
Thyroid hormone signaling pathway
ppad04925
Aldosterone synthesis and secretion
ppad04960
Aldosterone-regulated sodium reabsorption
ppad04961
Endocrine and other factor-regulated calcium reabsorption
ppad04964
Proximal tubule bicarbonate reclamation
ppad04970
Salivary secretion
ppad04971
Gastric acid secretion
ppad04972
Pancreatic secretion
ppad04973
Carbohydrate digestion and absorption
ppad04974
Protein digestion and absorption
ppad04976
Bile secretion
ppad04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
109257221 (ATP1A2)
04022 cGMP-PKG signaling pathway
109257221 (ATP1A2)
09140 Cellular Processes
09142 Cell motility
04820 Cytoskeleton in muscle cells
109257221 (ATP1A2)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
109257221 (ATP1A2)
04918 Thyroid hormone synthesis
109257221 (ATP1A2)
04919 Thyroid hormone signaling pathway
109257221 (ATP1A2)
04925 Aldosterone synthesis and secretion
109257221 (ATP1A2)
09153 Circulatory system
04260 Cardiac muscle contraction
109257221 (ATP1A2)
04261 Adrenergic signaling in cardiomyocytes
109257221 (ATP1A2)
09154 Digestive system
04970 Salivary secretion
109257221 (ATP1A2)
04971 Gastric acid secretion
109257221 (ATP1A2)
04972 Pancreatic secretion
109257221 (ATP1A2)
04976 Bile secretion
109257221 (ATP1A2)
04973 Carbohydrate digestion and absorption
109257221 (ATP1A2)
04974 Protein digestion and absorption
109257221 (ATP1A2)
04978 Mineral absorption
109257221 (ATP1A2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
109257221 (ATP1A2)
04961 Endocrine and other factor-regulated calcium reabsorption
109257221 (ATP1A2)
04964 Proximal tubule bicarbonate reclamation
109257221 (ATP1A2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ppad04147
]
109257221 (ATP1A2)
Enzymes [BR:
ppad01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.13 Na+/K+-exchanging ATPase
109257221 (ATP1A2)
Exosome [BR:
ppad04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
109257221 (ATP1A2)
Exosomal proteins of other body fluids (saliva and urine)
109257221 (ATP1A2)
Exosomal proteins of colorectal cancer cells
109257221 (ATP1A2)
Exosomal proteins of bladder cancer cells
109257221 (ATP1A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
Sigma70_r4
HAD
Motif
Other DBs
NCBI-GeneID:
109257221
NCBI-ProteinID:
XP_019288733
Ensembl:
ENSPPRG00000009924
LinkDB
All DBs
Position
Unknown
AA seq
1020 aa
AA seq
DB search
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKVQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKAC
VVHGSDLKDMTSEQLDEILRNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSMNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSIFQQGMKNKILIFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
NT seq
3063 nt
NT seq
+upstream
nt +downstream
nt
atgggccgtggggccggccgtgagtactcgcccgcggccaccacggcggagaatggaggc
ggcaagaagaagcagaaagagaaggagctggatgagttgaagaaggaggtggccatggac
gaccacaagctgtccttggatgagctgggccgcaaataccaagtggacctctccaagggc
ctcaccaaccagcgggcccaggacattctggctcgggatgggcccaacgccctcaccccg
cccccgaccacccctgagtgggtcaagttctgtcgccagctctttgggggcttctccatc
ctgctgtggatcggggccattctctgcttcctggcctacggcatccaggccgccatggag
gatgaaccatccaatgacaacctctacctgggtgtggtgctggcagccgtggtcatcgtc
accggctgcttctcctactaccaggaggccaagagctccaagatcatggattccttcaag
aacatggtgcctcagcaagccctggtggtgcgggaaggagagaaggtgcagatcaacgcc
gaggaggtggtggtgggagacctggtggaggtgaagggcggagaccgcgtgcccgcggac
ctccggatcatctcttctcacggctgcaaggtggataactcatctctaacaggcgagtcg
gagccccagacccgctcccccgagttcacccacgagaaccccctggagactcgtaatatc
tgtttcttctctaccaactgtgtggaaggcacggccaggggcatcgtgattgccacaggc
gaccggacagtgatgggccgcatagccacgctggcctcaggcctggaggtcggacggaca
cccatcgccatggagatcgaacacttcatccagctgatcacgggggtggccgtgttcctg
ggggtctccttcttcgtgctctccctcatcctgggctacagctggctggaggcggtcatc
ttcctcattggcatcatcgtggccaatgtgcctgagggtctgctggccactgtcaccgtg
tgtctgaccctgaccgccaagcgcatggcgcgcaagaactgcctggtgaagaacctggag
gcggtggagacgctgggctccacctccaccatctgctcggacaagacggggaccctcacc
cagaaccgcatgaccgtcgcccacatgtggttcgacaaccagatccatgaggccgacacc
accgaagatcagtccggggccacttttgacaagcgatcccccacgtggacggccctgtct
cggattgccggtctctgcaaccgcgctgtcttcaaggccgggcaggagaacatctccgtg
tcgaagcgggacacagccggcgacgcctccgagtcagctctgctcaagtgcatcgagctg
tcctgcggctccgtgaggaagatgagggatagaaaccccaaggtggcggagatccccttc
aattccaccaacaagtaccagctgtctatccacgagcgggaagacagcccccagagccac
gtgctggtgatgaagggagccccagagcgcatcctggaccggtgttccaccatcttggtg
cagggcaaggagatccctttggacaaggaaatgcaagacgcctttcagaacgcctacatg
gagctgggcgggctgggggagcgcgtgctggggttttgtcagctgaatctgccgtctggg
aagttccctcgcgggttcaaatttgacacagacgagctgaactttcccacggagaagctc
tgcttcgtggggctcatgtccatgatcgaccctccccgggctgccgtgccggacgccgtg
ggcaagtgtcgaagtgcgggcatcaaggtgatcatggtgactggggaccatccgatcaca
gccaaggccattgccaaaggtgtgggcattatatcagagggcaatgagactgtggaggac
atcgcagcccggctcaacattcctgtcagccaggtcaaccccagagaagccaaggcgtgc
gtcgtgcacggctcggacctgaaggacatgacgtcggagcagctggacgagatcctcagg
aaccacacggagatcgtgttcgcgcggacgtccccgcaacagaaactcatcatcgtggag
ggctgtcagaggcagggggccatcgtggcggtgacgggggacggcgtgaacgactccccc
gcgctgaagaaggctgacatcggcatcgccatgggcatctcgggctccgacgtgtcgaag
caggccgccgacatgatcctgctggacgacaacttcgcctccatcgtcacgggcgtggag
gagggccgcctcatctttgacaacctgaagaaatccatcgcgtacaccctgaccagcaac
atccccgagatcacccccttcctgctcttcatcatcgccaacatccccctgcctctgggc
accgtgaccatcctctgcatcgacctgggcacagacatggtcccggccatctccctggcc
tacgaggcggctgagagtgacatcatgaagcggcagcccaggaaccctcagacggacaag
ctggtgaatgagaggctcatcagcatggcctatggacagatcgggatgatccaggcactg
ggtggcttcttcacctacttcgtcatcctggcggagaacggtttcctgccatcacggctg
ctgggaatccgcctggactgggacgaccggtccatgaacgacctagaggacagctacgga
caggagtggacctacgagcagcggaaggtggtggagttcacgtgccacacggccttcttt
gccagcatcgtggtcgtgcagtgggccgacctcatcatctgcaagacccgccgtaactcc
atcttccagcagggcatgaagaacaagattctgatttttgggctcctggaggagacagcg
ctggcggccttcctgtcctactgcccgggcatgggtgtggccctccgcatgtacccactc
aaggtcacttggtggttctgtgccttcccctacagcctcctcatattcatctacgatgag
gtccgaaagctcatcctgcggcggtatcccggcggctgggtggagaaggagacgtactac
tga
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