Panthera pardus (leopard): 109257265
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Entry
109257265 CDS
T06062
Symbol
NDUFS2
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1
KO
K03935
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:
7.1.1.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00190
Oxidative phosphorylation
ppad01100
Metabolic pathways
ppad04714
Thermogenesis
ppad04723
Retrograde endocannabinoid signaling
ppad04932
Non-alcoholic fatty liver disease
ppad05010
Alzheimer disease
ppad05012
Parkinson disease
ppad05014
Amyotrophic lateral sclerosis
ppad05016
Huntington disease
ppad05020
Prion disease
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05208
Chemical carcinogenesis - reactive oxygen species
ppad05415
Diabetic cardiomyopathy
Module
ppad_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
109257265 (NDUFS2)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
109257265 (NDUFS2)
09159 Environmental adaptation
04714 Thermogenesis
109257265 (NDUFS2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
109257265 (NDUFS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
109257265 (NDUFS2)
05012 Parkinson disease
109257265 (NDUFS2)
05014 Amyotrophic lateral sclerosis
109257265 (NDUFS2)
05016 Huntington disease
109257265 (NDUFS2)
05020 Prion disease
109257265 (NDUFS2)
05022 Pathways of neurodegeneration - multiple diseases
109257265 (NDUFS2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109257265 (NDUFS2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109257265 (NDUFS2)
Enzymes [BR:
ppad01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
109257265 (NDUFS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Complex1_49kDa
NiFeSe_Hases
Motif
Other DBs
NCBI-GeneID:
109257265
NCBI-ProteinID:
XP_019288803
Ensembl:
ENSPPRG00000007116
UniProt:
A0A9V1EU18
LinkDB
All DBs
Position
Unknown
AA seq
463 aa
AA seq
DB search
MAALRALRSLRGVAAQALRSGVGGRLPVQPSRGSRQWQPDMEWAEQFGGAVMYPTKETAH
WKPPPWNDVDPPKDTMVTNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGL
MDDIYEFSKNFSLRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVDFDVPIGSRGDCYDRYLCRVEEMRQSLRIILQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctcagggctctgcgcagcctccgcggcgtcgcggcccaggcgctgcggtcc
ggggtcgggggccggctgcccgttcagcccagcagaggttctcggcaatggcagccagat
atggaatgggcagagcagtttgggggagcggtcatgtaccccaccaaggaaacggcccac
tggaagcctccaccttggaatgatgtggaccctccaaaggacacaatggtgacgaacctg
accctgaactttgggccccagcacccagcagcccatggagtcctgcgactagtgatggag
ttgagtggggagatggtgcgcaaatgtgacccccacatcgggcttctgcaccgaggaacc
gagaagctcattgaatacaagacctatctgcaggctcttccatactttgaccggctagac
tatgtgtccatgatgtgtaatgagcaggcctactcactggctgtggagaagttactcaat
atccagcctccgccccgggcacagtggatccgagtgctgtttggagaaatcacacggctt
ttgaaccacattatggctgtgaccacacatgccctggacattggggctatgacccctttc
ttctggatgtttgaggagagggagaagatgtttgaattctacgagcgcgtgtctggggct
cggatgcatgctgcctacgtccggccaggaggtgtgcaccaggacctgcctcttgggctt
atggatgacatttatgagttttctaagaacttctcacttcggattgatgagttggaagag
atgctgaccaacaacaggatctggcgaaatcggacagtcgacattggggtcgtaacagcc
gaagacgcactgaactatggatttagtggcgtgatgctgcggggctcaggcatccagtgg
gacctgcggaagacccagccctatgatgtttacgaccaggtggactttgatgttcccata
ggctctcgaggggactgctacgacaggtacctgtgtcgggtagaggagatgcgccagtcc
cttcgaatcatcttgcaatgtctcaacaagatgcctcctggggagatcaaggtcgatgat
gccaaagtgtctccgcctaagcgagcagagatgaagacttccatggaatcactgattcac
cactttaagttgtatacagagggctaccaggttcccccgggggccacgtacaccgccatc
gaggctcctaagggagagttcggggtgtacctggtgtccgatggcagcagccgcccttac
cgatgcaagatcaaggctcctggtttcgcccacctggccggtttggacaagatgtcaaag
ggacacatgctggcggacgttgttgccatcataggtacccaagatattgtgtttggagaa
gtggatcggtga
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