Panthera pardus (leopard): 109257701
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Entry
109257701 CDS
T06062
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2
KO
K02085
adenomatosis polyposis coli protein
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04310
Wnt signaling pathway
ppad04390
Hippo signaling pathway
ppad04550
Signaling pathways regulating pluripotency of stem cells
ppad04810
Regulation of actin cytoskeleton
ppad04934
Cushing syndrome
ppad05010
Alzheimer disease
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05165
Human papillomavirus infection
ppad05200
Pathways in cancer
ppad05206
MicroRNAs in cancer
ppad05210
Colorectal cancer
ppad05213
Endometrial cancer
ppad05217
Basal cell carcinoma
ppad05224
Breast cancer
ppad05225
Hepatocellular carcinoma
ppad05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
109257701 (APC2)
04390 Hippo signaling pathway
109257701 (APC2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
109257701 (APC2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109257701 (APC2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109257701 (APC2)
05206 MicroRNAs in cancer
109257701 (APC2)
09162 Cancer: specific types
05210 Colorectal cancer
109257701 (APC2)
05225 Hepatocellular carcinoma
109257701 (APC2)
05226 Gastric cancer
109257701 (APC2)
05217 Basal cell carcinoma
109257701 (APC2)
05213 Endometrial cancer
109257701 (APC2)
05224 Breast cancer
109257701 (APC2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
109257701 (APC2)
09164 Neurodegenerative disease
05010 Alzheimer disease
109257701 (APC2)
05022 Pathways of neurodegeneration - multiple diseases
109257701 (APC2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
109257701 (APC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ppad01009
]
109257701 (APC2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ppad03036
]
109257701 (APC2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
ppad04812
]
109257701 (APC2)
Protein phosphatases and associated proteins [BR:
ppad01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
109257701 (APC2)
Chromosome and associated proteins [BR:
ppad03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
109257701 (APC2)
Cytoskeleton proteins [BR:
ppad04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
109257701 (APC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
APC_basic
APC_rep
APC_N_CC
Suppressor_APC
Arm
APC_r
Arm_APC_u3
SAMP
Wtap
bZIP_1
MPS2
HEAT_ULK4
Sec7-like_HUS
PDC10_C
HALZ
Sec2p
Herpes_BLRF2
CCDC138_cc
Motif
Other DBs
NCBI-GeneID:
109257701
NCBI-ProteinID:
XP_019289562
LinkDB
All DBs
Position
Unknown
AA seq
2285 aa
AA seq
DB search
MGLLGLLSLLHSAFFGDQALQELKMTSSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEAGVLVSLGQTEVLEQLKALQMDITSLYNLKFQPPAL
GPEPTGRTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDQELLSAQDRVQQTEPQALLAVKSVPVDEDPETEVPTHPEDGVPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGAGGRDGSPG
ATGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAEG
GGASGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHRMTRDP
LNLALRRYAGMTLTNLTFGDVANKVSGAGRRAGRVSALQARACLDLMPVVSSILRNLSWR
ADIHSKKVLREVGSMTALMRCVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDGALG
FLVRTLTYKCQSNSLAVIESGGGILRNVSSLIATREDYRQVLRDHSCLQTLLQHLTSHSL
TIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRP
AKYRATATAVSPGACAPSLYVRKQRALEAELDTRHLARALDHLEKQGLPEAEAEAASKKP
LPPLRHLDGLARDYASDSGCFDDDEAPSLAAAASTAEPASPAVLSLFLGSPFLQGQALAR
APPARRSGPEAEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSGD
PGQEAPREGRAQSCSPCRRPEGRRQEAGGRAHPLLRLQAAPASLSNDSLNSGSSAGDGRC
PREHTRPCPLAVLAEHHEGAPCSQARPSRLDLSLPGGREPAGRDGPAADSCVRTIKLSPT
YQHVPLFEGHPRAGAGAGPLAAGARKQAWLPTEGLSQLPEQPAAETAPLRLSRCSSLSSL
SSAGRPGPSEAGDLDSDSSLEALEEAGPGKADPDGAWLGPGAASLPVAIPAPHRGRGLGA
EDTTPSSSSENCVQETPLVLSRCSSVSSLSSFESPSIASSVPSDPCSGLGSGTVSPSELP
DSPGQTMPPSRSKTPPPAPAPPGERESTQFSLQWESYVKRFLDIADRRERCRLPSELDAG
SVRFTVEKPDENFSCASSLSALALHEHYVQKDVELRLLPPACPDRGGPGPGPGPGPGPHL
AGHRRRDEAAGCLEGPAAADRELQLLRECLGAAVPARLRKVASALVPGRRALPVPVYMLV
PAPARGDDSCTDSAEGTPVTFSSATSLSDETLQGPPRDPPAGQAAGRKTAGREAAARQAT
GHRHGAWGGGRSAEQARGAGTSREGLELPLRQPSSACADRDGPRPGQARGDGAPQSLCLT
TPTEEAVYCFYDNDSDEEPSEAVAVAPPRRASAIPRAVKREHPAGRKDAQATPKAAAKAP
PAARAQPSLIADETPPCYSLSSSASSLSEPEPPEQPASRPRAPEPAVAKVVGPGGRCSGA
PSPRAGTGTGPGTGPLRRCVGSAVPGRRLQASGPRRRKPQAARPDKRPAERPQERGDEAA
GSDQASDLDSVEWRAIQEGANSIVTWLHQAAAAATHEASSGSDSILSESGLSGSTLQPPV
HRKGQRLQAGGAARPRPEKRDSTQARHGPSGPEKLRGAQKTACRVPAVLRGRTVIYVPSP
APRAQPRGHPGTRVAPRKVGAPAQPAAPMSLISQQRQRSRSLHRPGKISELAALSPPQRS
ATPPARLAKAPSSGSSPASPASQPPPRRPPSGPQAAGPLPGPGASLAPQTPARALLSKQH
KTQKSPVRIPFMQRPARRGPPALARAAPEPGPRGRAGAEGSPGARGGRLGLVRVASARSS
GSESSDRSGFRRQLTFVKESAGLPRRRRSEVAAPEAAPSASQGGSPRRGRPALPAVFLCS
SRCDELRAAPRRPPAARPSPGERPPRRPSSESPSRLPVRTPAARPEAVKRYASLPHISAL
PGPAADAARRSSDGEARPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLVGASPEEG
PGGPPQRKTSDAVVQTEDFVAAKTNSSTSPSLESRGPPQALGGGPTSFPGSDVDGPCPPK
APTSAPFVHEGLGVAVGGFPTSRHGSPSRAARVPPFNYVPSPMVAATADLAAEKAPTAAP
ASLLE
NT seq
6858 nt
NT seq
+upstream
nt +downstream
nt
atggggctcttggggctgctgagcctgctgcactcagccttcttcggggaccaggcgctg
caggagctgaagatgacgagctccgtggcgccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgaggcaggagctgcgagacaactcgagccacctg
tccaagctagagacggagacgtccggcatgaaggaggtcctgaagcacttacaaggcaag
ctggagcaggaggctggagtgctggtgtccttggggcagacggaggtgctggaacagctg
aaagccctgcagatggacatcaccagcctgtacaacctcaagttccagccccccgcccta
ggtcctgagcccactggccggacccccgaaggaagtccagtacacggctccgggccttct
aaggacagctttggggagctgagccgggcgaccatccggctgctggaggaactggaccgg
gagaggtgcttcctgttgaacgagatcgagaaggaggagaaggagaagctctggtattac
tcacagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttc
tcgatgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcg
ctgatggaagagcgcttcggcacctcggacgagatggtgcagcgcgcgcagatccgcgct
tctcgcttggagcaaatcgatcaggagctgctgtccgcacaggaccgggtgcaacagaca
gagccccaggccctgctggcggtgaagtcggtgccggtggacgaggatccagagactgaa
gtccccacacaccctgaggacggtgtccctcagcccggcaacagcaaggtggaggtggtc
ttctggctgctgtccatgctggcaacgcgtgaccaggaggacacggcgcgcaccctgctg
gccatgtccagctcgccggagagctgcgtggccatgcgccggtcggggtgcctgccgctg
ctgctgcagatcctgcacggcaccgaggccggcgctgggggtcgcgacggaagccccggg
gcgacgggcgccaaggacgcacgcatgcgcgccaacgcggcgctgcacaacatcgtcttc
tcgcaacctgaccagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcag
atccgggcctattgtgagacctgctgggactggctgcaggccagggacggcgccgaggga
ggcggcgccagcggcgctcccgtccccatcgagccccagatctgccaggccacctgtgcc
gtgatgaagctgtcttttgacgaggaataccgccgagccatgaacgagctgggtgggctg
caggccgtggcagagttactgcaagttgactacgagatgcacagaatgacccgggacccg
ctgaacctcgccctccgtcgatacgccggcatgaccctcaccaacctcacctttggagac
gtcgccaacaaggtgtctggggccggccggagggcgggcagggtcagcgcgctccaggcc
cgggcctgcctcgacctcatgcccgttgtgtccagcatcctgcgcaacctgtcctggcgg
gccgacatccacagcaagaaggtgctgagggaggtgggcagcatgaccgccctgatgcgg
tgcgtccttcgagcctccaaggagtccaccctgaagagcgtgctcagcgccctgtggaac
ctgtcggcgcacagcacggagaacaaggcggccatctgccaggtggacggcgccctgggc
ttcctggtgaggacactgacctacaagtgccagagcaactcgctggccgtcatcgagagt
ggcggcggcatcctgcgcaacgtgtccagcctcatcgccacgcgggaggactacaggcag
gtgctgcgggaccacagctgcctgcagacgctgctgcagcacctgacgtcccacagcctg
accatcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagcccgcgcgac
caggagctgctgtgggacctgggggccgtgggcatgctgcggaacctggtgcactccaag
cacaagatgatcgccatgggcagcgccgcggccctgcgcaacctgctggcccaccggccc
gccaagtaccgggcgacggccaccgccgtgtcccccggcgcgtgcgcacccagtctgtac
gtgaggaagcagcgggcgctggaggccgagctggacacgcggcatctggcccgggcgctc
gaccacctggagaagcagggcctgcccgaggccgaggccgaggccgcctccaagaagccg
ctgccgcccctgcggcacctggacgggctggcccgggactacgcctccgactccggctgc
ttcgacgacgacgaggcgccctccctggctgccgccgcctcgaccgccgagcccgccagc
cccgccgtgctgtccctcttcctgggcagccccttcctgcagggacaggctctggcccgc
gccccgcccgcccgccgcagcggcccggaggcggagaaggaggccggcggggaggcggcc
gtggcggccagggccaaggccaagctggcgctggcggtggcgcggatcgaccggctggtg
gaggacatctcagccctgcacacctcgtccgacgacagcttcagcctcagctccggggac
cccgggcaggaggccccgcgggagggccgcgcccagtcctgctccccttgccggcggcca
gagggccggcggcaggaggccggcggccgggcccacccgctgctgcggctccaggccgcc
cccgccagcctgtccaacgacagtctcaacagcggcagcagcgccggtgacgggcgctgt
ccccgcgagcacacgaggccctgcccgctggccgtgctggccgagcaccacgagggggcc
ccgtgcagccaggcgcggcccagccggctggacctcagcctgccgggcggccgggagccg
gccgggagggacggccctgcggccgactcctgcgtgcgcaccatcaagctgtcgcccacc
taccagcacgtgccgctcttcgagggccaccccagggcgggggcgggcgcggggcccctg
gccgccggagcccggaagcaggcctggctgcccacggagggcctgagccagctgcccgag
cagccggcggcagagacggcgcccctccgcctgtcccgctgcagctctctgtcctcgctg
tcctcggccggccgcccgggccccagtgaggccggggacctggacagcgactcgtccctg
gaggcactggaggaggcgggacccggcaaggcggacccggacggagcctggctcgggccc
ggggccgcctccctgcccgtggccatcccggcgccgcaccggggccgcggcctgggggcg
gaggacaccacgccgtccagctcctcggagaactgcgtgcaggagacgccgctggtgctg
agccgctgcagctccgtgagctccttgagcagtttcgagagcccgtccatcgccagctcc
gtccccagcgacccgtgcagcgggctgggcagcggcacggtcagccccagcgagctgccc
gacagccccgggcagaccatgccgcccagccgcagcaagacgcccccgccggcccctgcg
ccccccggcgagcgcgagagcacccagttcagcttgcagtgggagagctacgtgaagcgg
ttcctggacatcgccgaccgccgggagcgctgccggctgccgtcggagctcgacgccggc
agcgtccgcttcacggtggagaagccggacgagaacttctcgtgcgcctcgagcctcagc
gcgctggccctgcacgagcactacgtgcagaaggatgtggagctgcggctgctgcccccc
gcctgcccggatcgcggcggccccggccccggccccggccccggccccggcccgcacctc
gcggggcaccgccggcgggacgaggccgctgggtgcctggaggggccggcagccgccgac
cgggagctgcagctgctgcgcgagtgcctgggggcagccgtgcccgcccggctccgcaag
gtggcctcggccctggtgcccggccgccgcgcgctgcccgtgcctgtgtacatgctggtg
cccgcccccgcccggggggacgactcatgcaccgactcagccgagggcacgccggtcacc
ttctccagtgccacctcgctcagcgacgagacgctgcagggacctcccagggacccaccc
gccgggcaggcagccggccggaagaccgcaggtcgggaggccgccgccaggcaggccacc
gggcaccgccacggggcgtggggcgggggccggagcgcagagcaggcccggggggcgggc
acgagccgggaggggctggagctgcccctccgccagccctcgagcgcctgcgcggacagg
gacggcccccgcccgggccaggcacgtggggacggggcaccgcagtcgctgtgcctcacg
acgcccaccgaggaggccgtgtactgcttctacgacaatgactccgatgaagaaccgtcc
gaggcggtggcggtggcgcccccgcggcgggcgtccgccatcccccgtgccgtgaagaga
gagcacccggccggcaggaaggacgcacaggccacacccaaggccgcggccaaggccccg
cccgctgcccgcgcccagcccagcctcatcgccgacgagaccccgccatgctattccctg
agctcctccgccagctcgctcagcgagcctgagccccctgagcagccggccagccggccc
cgtgctcccgagccggccgtcgccaaagtcgtgggcccggggggcagatgcagcggcgcc
cccagcccgcgggcggggacggggacggggccagggacggggccgctccggcgctgtgtc
gggtcagccgtgcccgggcgccggctccaggcgtcaggcccgcggcgccgcaagccccag
gctgcccggccagacaagcggccagcggagcggccccaggagcgcggtgacgaggcggcg
ggctcagaccaggcctccgacctggacagcgtcgagtggcgcgccatccaagagggcgcc
aactccatcgtcacgtggctgcaccaggcggcggccgcggccacccacgaggcctcatct
ggctctgactccatcctgtcggagtccgggctgtcaggctccaccctgcagccgccggtg
cacaggaagggacagcggctgcaggcgggcggtgccgcgaggccgaggccggagaagcgg
gactcaacccaggcccggcacggccccagtggccccgagaagctgcgcggtgctcagaag
acggcgtgcagggtgccggccgtgctccggggacggaccgtgatctatgtgcccagcccg
gccccccgggcacagcccagaggccaccccggcacccgggtggcaccgaggaaggtggga
gcccctgcgcagcccgcagccccnatgtccctaattagccagcagaggcagcggtctcga
agcctacaccggccgggcaagatctcggagctggcggcactgagccccccgcagcggagc
gccacgccgcccgcccgcctggccaaggccccctcgtccggctcctccccggcctccccg
gcctcccagcccccgcccaggaggccgccctcgggcccccaggctgcggggcccctacct
gggcccggggcgtctctggcgccccagacgcccgcgcgggccctactgtccaagcagcac
aagacgcagaagtcacccgtgcggatccccttcatgcagaggcccgccaggcgggggccg
ccagccctggcccgggcagccccggagccgggccccaggggccgggcaggagccgaggga
agcccgggcgcccgagggggccgcctgggcctggtgcgcgtggcctccgcccgctccagt
ggcagcgagtcctccgaccgctcgggtttccggcggcagctgaccttcgtcaaggagtcc
gcgggcctgccgcgccgccgccgctcagaggtggccgcgcccgaggccgcgccctccgcc
tcccagggcggctccccccggcgcggtcggcccgccctgcccgcggtcttcctgtgctcc
tcgcgctgcgacgagctgcgggcggccccccgacgaccccccgcagccaggcccagcccc
ggcgagcggccgccgcggcgccccagctccgaaagcccgtcccgcctgcccgtccgcacg
ccggccgcccggcccgaggccgtcaagcgctacgcctccctgccgcacatcagcgcgctg
ccggggcccgcggccgacgccgcccgccgcagcagcgacggggaggcccggccgctcccg
agggtggcggccccgggcaccacgtggcgtcgcatccgggacgaggacgttccgcacatc
cttcggagcacgctgcccgccaccgccctgcccctggtgggcgcctcccccgaggagggc
cccggcgggcccccgcagcgcaagaccagcgacgccgtggtccagaccgaggacttcgtt
gccgccaagaccaactccagcacgtctccaagcctggagagcagggggcccccccaagcc
ctgggcggcggccccacatccttccctggcagcgatgtggatgggccctgcccccccaag
gcgcccacctctgcccccttcgtccatgagggcctgggggtggccgtgggaggctttccc
accagccggcacggctcccccagccgcgcggcccgcgtgccccccttcaactacgtgccc
agccccatggtggcagccaccgccgacttggccgcagagaaagcccccaccgctgccccc
gccagccttctggaatag
DBGET
integrated database retrieval system
