Panthera pardus (leopard): 109257969
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Entry
109257969 CDS
T06062
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00280
Valine, leucine and isoleucine degradation
ppad00640
Propanoate metabolism
ppad00785
Lipoic acid metabolism
ppad01100
Metabolic pathways
ppad01210
2-Oxocarboxylic acid metabolism
Module
ppad_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
109257969 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
109257969 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
109257969 (BCKDHA)
Enzymes [BR:
ppad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
109257969 (BCKDHA)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
109257969
NCBI-ProteinID:
XP_019289998
Ensembl:
ENSPPRG00000003740
UniProt:
A0A9V1EW14
LinkDB
All DBs
Position
Unknown
AA seq
446 aa
AA seq
DB search
MAVAAAAAKLRGSGRGLGQAGVLLLRRLGARGLARYHPRRQEQQHFPSLDDKPQFPGASA
EFVDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQETVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDSTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNASDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPVIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQGRGWWDDEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQ
LRKQQESLARHLQAYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgctgcggcgaagctccggggctcgggtcgaggcttgggccaggct
ggcgtcctgctcctgcggcggcttggtgctcgggggctggctagatatcaccctcggagg
caggagcagcagcactttccatccctggatgacaagccccagttccccggggcctcggcg
gagtttgtagacaagctagaattcatccagcccaatgtcatctctgggatccccgtctat
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccacctgccccag
gagacggtgctcaagttctacaagagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggagggg
acacatgtggggagcgcggcagcgctggacagcacggacctggtgtttggccagtaccgg
gaggcaggtgtgctaatgtaccgggactaccccctggagctgttcatggcccagtgctat
ggcaacgcgagcgacctgggcaaggggcgccagatgcccgtgcactatggctgcaaggag
cgccacttcgtcaccatctcctctccgctggccacgcagatcccgcaggcggtgggggcg
gcctatgcggccaagcgtgccaacgccaacagagtggtcatctgttacttcggggagggg
gcggccagcgagggggatgcccacgccggcttcaacttcgccgccaccctcgagtgcccg
gtcatcttcttctgccggaacaacggctatgccatctccacgcccacctctgagcagtac
cgcggggacggcatcgctgctcgaggcccgggctacggcatcatgtccatccgcgtggac
ggcaacgatgtgtttgccgtgtacaacgccaccaaggaggcccggcggcgggccgtggct
gagaaccagcccttcctcattgaggccatgacctacaggatcgggcaccacagcaccagt
gacgacagctcggcctaccgctcggtggacgaggtcaattactgggacaagcaggaccac
cccatctcccggctgcggcactacctgcagggccgaggctggtgggacgacgagcaggag
aaggcctggagaaagcagtcccgcaagaaggtgatggaggcctttgagcaggcggagcgg
aagccgaagcccaaccccaacctgctcttctctgacgtgtaccaggagatgccggcccag
cttcgcaagcagcaggagtccctggcccggcacctccaggcctacggcgagcactacccc
ctggaccacttcgagaagtga
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