KEGG   Panthera pardus (leopard): 109262874
Entry
109262874         CDS       T06062                                 
Symbol
HERC1
Name
(RefSeq) probable E3 ubiquitin-protein ligase HERC1 isoform X1
  KO
K10594  E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    109262874 (HERC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ppad04121]
    109262874 (HERC1)
Enzymes [BR:ppad01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     109262874 (HERC1)
Ubiquitin system [BR:ppad04121]
 Ubiquitin ligases (E3)
  HECT type E3
   109262874 (HERC1)
SSDB
Motif
Pfam: RCC1 RCC1_2 HECT SPRY WD40_CDC20-Fz WD40 WD40_WDHD1_1st WD40_Prp19 Beta-prop_CAF1B_HIR1 Beta-prop_EML_2 Beta-prop_TEP1_2nd Beta-prop_IFT140_1st Beta-prop_WDR35_TULP_N Beta-prop_RIG_2nd WDR55 Beta-prop_WDR75_1st WD40_MABP1-WDR62_2nd Na_trans_assoc Beta-prop_EML CLASP_N
Other DBs
NCBI-GeneID: 109262874
NCBI-ProteinID: XP_019297390
Ensembl: ENSPPRG00000006219
LinkDB
Position
Unknown
AA seq 4887 aa
MATMVPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGP
QLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNK
YHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMP
VSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGAD
TLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVNSMEKSKLLSSQEGMISFDCFM
TILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSI
QTGDTPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVIST
DGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVF
SWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDF
GRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTN
RVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIE
ELAATRIVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAI
QQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLP
FPSSREHHSFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQE
VVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVA
SLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAF
GELEKNSDKFLLGTSSSENSQPAHLHELLCSLQKQLLAFCHINNISENSSSVALLHKHLQ
LLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARP
LLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPELIDPAGMPLPQPAQSWVWLVD
LERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLEVA
LSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLL
DTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRS
SSRDRWISENQDSADVDPQEHSFTRTIDEEAEMEEQAERDREEGHPEPEDEEEEREHEVM
TAGNLVFVLHVTEIFQCFLSAREVARSRDRDRMNSGAGSGARADDPPPQSQQERRVSTDL
PEGQDVYTAACNSVIHRCALLILGVSPVIEELQKRKEEGQLQQPSTSASEGGGLMTRSES
LTAESRLVHASPNYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQ
LESLSDSWARLKHSRDWLCNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKE
PEESMSTSPQASIIAMEQQQLRAELRLEALHQILVLLSGLEEKGSISLTGSRSNLGFQSS
TLLTSVRLQFLAGCFGLGTVGHAGAKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQ
LSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTM
LGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKN
LLSQAGVLLMASFGEGEGEEGEEEERKVDSSGETEKRDFRAALRKQHAAELHLGDFLVFL
RRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESG
VEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQ
EVSFDPEKAQCCLVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVG
VSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFG
KNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAV
LAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEMRE
EKESKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRH
ATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLPFDVARFRGLTAS
VLLDLTYLTGIHEDMGKQSTKRHEKKHRHESEEKGDVEQKTENESALDTRTGLTSDDVKN
QGTTASKSENEIASFSLDPTLPSVESQHQITEGKRRNHEHISKNHDIAQSEIRAVQLSYL
YLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMV
KRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQQAEESDQAQQAQ
TPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTT
TVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSARPANRTALSDPSSRLSTSPPPP
AIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPGSTAD
SRHGAAVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESADNLDHAENAASGSGPPAR
GRSAVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELE
IDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECSVVSF
NQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKSK
TTSSERYKGQAPDLIGKQDSVYEEDWDMLDVDEDEKLTGEEEFELLAGPLGLNDRRIVPE
PVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRITLGEQAAALANPHDRV
VALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAG
RAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQN
LISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRP
NYDKSEVEKKGLTAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRT
LAAHDRDNQTTPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRV
WNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQV
NGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHCRE
LEHCYRKDVSVTCIAWFSEDRPFAVGFFDGKLLLGTKEPLEKGGIVLIDAHKDTLVSMKW
DPTGHILMTCAKEENVKLWGPISGCWRCLHSLCHPSIVNGIAWCSLPGKGSKLHLLMATG
CQSGLVCVWRIPQDTTQTSVTSSEGWWDQESNCQDGYRKSAGAKCVYQLRGHITPVRTVA
FSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPDVGVAACSNRSKDVL
VVNCTAEWAAANHVLATCRTALKQQGVLGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVC
GDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPASWNPNEWAWLECFSTTI
KAAEALTNGAQFPESFTVPDLEPVPEDELTFLMDNSKWINGMDEQIMSWATSRPEDWHLG
GKCDVYLWGAGRHGQLAEAGRNVMVPAAAPSFSQAQQVICGQNCTFVIQANGTVLACGEG
SYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKL
GHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNK
KLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVD
VLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIE
DVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNVRQISAGRCH
SAAWTAPPVPPRAPGVSVPLQLGLPDAVPPQYGALREVSIHTARARLRLLYHFSDLMYSS
WRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQI
TVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITE
MCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKK
PLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSF
VGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPL
LSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMR
FVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAI
NNCRSIDMDNYMLSRNVDNAEGSDTDY
NT seq 14664 nt   +upstreamnt  +downstreamnt
atggcaactatggttccaccagtgaaactgaaatggcttgaacacctgaacagctcctgg
attacagaagatagtgaatctattgctacaagagagggagttgctgttctgtattctaaa
ctggtcagcaataaagaagtagtacctttgccccaacaagttttgtgcctcaaaggacca
cagttgccagactttgaacgtgagtctctttcaagtgatgagcaggaccactatttggat
gcccttcttagcagccagctagcactagcgaagatggtatgttcagattccccatttgct
ggggcacttcgaaaacgactgcttgtactccagcgtgtcttttatgcactttcgaataaa
taccatgacaaaggcaaagtgaaacagcagcagcattctccggagagcagctctggttca
gcagatgtccattctgttagtgaacgtccccggtcaagcactgatgcacttatagaaatg
ggtgttcgaactggtctaagtttattatttgcacttctaagacaaagttggatgatgcct
gtgtcaggacctggtcttagtctttgcaacgacgttattcatactgcaattgaagttgtc
agctctttgccaccattatctttagcaaatgaaagcaagattcctccaatgggtttggac
tgcttatcacaagtgacaacatttcttaaaggagtaactattcccaattctggggcagac
actttaggtcgcagattagcttctgagttgctgcttggtttagcagctcagcgaggctct
ttgcggtaccttcttgaatggatagaaatggctttgggggcttcagcggttgtaaattcc
atggagaaaagcaaactactatcaagccaggaaggaatgatcagctttgactgctttatg
actatattaatgcagatgaggcgttctttgggttcatctgctgatcgaagtcagtggagg
gaaccaaccagaacatctgatggcttgtgctcactctatgaggcagctttatgtctcttt
gaagaggtttgcagaatggcttctgattactcaagaacgtgtgctagcccagatagcatt
cagactggtgacactcccattgtctcagaaacctgtgaggtctatgtttgggggagcaat
agcagccatcagttggtggaaggcacacaggagaaaatattacagcccaaactggctccc
agtttctctgatgctcaaactattgaagctgggcaatactgcacttttgttatttctacg
gatggctctgtcagagcttgtggtaaaggcagctatggaagactgggccttggagattct
aataatcagtccactttaaagaagttaacatttgaacctcacaggtccattaaaaaggtt
tcatcttctaaaggatctgatggtcacactttagcttttacaacagaaggagaagtcttc
agttggggagatggtgattatgggaaactgggacatggaaatagttcaacacagaaatat
cccaagcttattcagggccctctgcagggaaaggtagttgtttgtgtgtctgctggatac
agacatagtgctgctgtcacagaggatggtgaattatacacatggggtgaaggagacttt
ggaagattaggtcatggtgacagtaatagccgtaacattccaacattagtgaaagacatt
agcaacgtaggagaggtttcttgtggcagttcacatactattgctttgtctaaagatggg
agaactgtatggtcttttggaggaggagacaatggcaaactcggccatggcgatactaac
agagtgtataagcctaaagttgttgaagctttacaaggaatgttcattcgcaaagtttgt
gctgggagccagtcttcacttgctttaacatcaacagggcaggtctatgcttggggctgt
ggagcttgtctgggttgtggttcttcagaagctactgctttgagacccaagcttattgaa
gaactggctgccacaagaatagttgatatttctattggagacagtcattgtttggctctt
tctcacgataatgaagtttatgcctggggcaataattcgatggggcagtgtggccaagga
aattccacaggtcctattactaaaccaaagaaagtgagtggcttagatggcatagctatt
cagcagatttctgctggaacatcacatagtctggcatggactgctcttcctagggataga
caagttgttgcgtggcaccgaccttattgtgtagatcttgaagagagtaccttctcacac
ctgcgttcttttcttgagagatactgtgataaaataaacagtgagattcccccactccct
ttcccttcatcaagggaacaccacagtttcctcaagctgtgcctgaagctgctttcaaat
caccttgctcttgcgcttgcgggaggggtggctaccagcattcttgggagacaggcaggt
ccacttcgaaatttgctcttcagactgatggattcaactgtcccagatgaaattcaagag
gtggtaattgaaactctgtcagtgggagcaaccatgctattaccaccattacgagaacgt
atggagttacttcattctcttttgccccaaggacctgatagatgggaaagcttatctaaa
ggacagagaatgcaactggatatcattctgacaagtttacaagatcatacccatgtagct
tccttacttggctatagctcaccttctgatgctgctgacctctcttctgtttgtactggc
tatggaaacctgtcagatcaaccttatggcactcagagctgccatccagacactcatctg
gctgaaattttgatgaaaactctcttaagaaatttaggattttatacagatcaagcattt
ggagagctagaaaagaatagtgataaatttctacttggaacatcatcttcggaaaacagt
cagcctgctcatcttcatgaactcctgtgttcactgcaaaaacaactgctggcattttgt
catatcaataacattagtgagaactcaagcagcgtggcattgcttcataaacaccttcag
ctcttgttgcctcatgccacagatatttattcacgttcggcaaatttgctcaaagaaagt
ccttggaatggcagtgttggagaaaaattaagagatgtgatatatgtctcagctgcaggg
agtatgctctgccagattgttaactccctactgttgctccctgtgtcggtggcacggcct
ctcttgagttacctcctcgacttgttgccacctcttgattgccttaacagactcctgcca
gctgccgctcttttagaagaccaagagttacagtggcctcttcatggaggaccagaactg
attgatcctgccggcatgccgttacctcagccagctcagtcctgggtgtggcttgtggat
ctggaaagaacgattgctctccttattgggcggtgtcttggtggtatgcttcagggctcc
cctgtgtctccagaggaacaggacaccgcatattggatgaaaacaccactttttagtgat
ggtgtagaaatggacacccctcagctagataaatgtatgagttgcctgctagaagtagct
ctttcgggaaatgaagaacagaagccttttgattataaactgcggcctgaaattgctgtc
tatgtagacttggcattgggttgttcaaaagagcctgctcgaagtctttggatcagcatg
caggattatgctgttagtaaagattgggacagtgcaactttaagcaacgagtcactcttg
gacactgtgtctagatttgttcttgcagcccttctgaaacatacaaatttacttagccaa
gcatgtggagaaagccgatatcagcctggtaaaagcttgtcagaagtgtaccgttgtgtg
tacaaagttcgaagtcgtttacttgcttgcaagaaccttgaacttattcagaccaggtca
tcatcacgagacagatggatctcggaaaaccaggactctgcagatgttgatcctcaggag
cattcgtttacccggaccattgatgaagaagctgaaatggaagaacaggctgagcgagac
cgggaagaggggcatcccgagccggaggatgaagaagaagaacgggaacatgaagtgatg
acagctggcaaccttgtttttgtgttgcatgttacagaaatctttcagtgtttcctctca
gcccgtgaagtagctcgtagccgagatcgagatagaatgaacagtggggcagggtctggg
gctcgagctgatgatccacctccccagtctcagcaagagcgaagggtcagcacagacctt
cctgagggccaggatgtgtacaccgctgcctgcaactctgtgatccatcggtgtgccctg
ttaatattaggagtaagtcctgtgattgaggagcttcagaagcggaaggaagaaggacag
ttgcagcagccttcaacaagtgcctctgaagggggtggacttatgaccaggagtgaaagt
cttactgcagagagccggctagtccatgcaagtccaaattatagactgatcaaatcgagg
agtgaatctgatttgtctcagcctgaatcagatgaagagggttacgcgctgagtggaaga
cgaaatgttgatttggatttggcatcatctcatagaaagagaggtcctatgcacagtcaa
ttggaatccttgagtgactcttgggctcgcctgaaacatagcagagactggttatgcaac
tcctcttactcctttgagtctgattttgatcttaccaagtctttgggagttcacactttg
atcgaaaatgttgtaagctttgtgagtggagatgtggggaatgctccaggttttaaagag
ccagaagaaagtatgtctacgagtccccaggcctctatcattgcaatggaacagcagcag
ttaagggcagaactacgtttagaagcacttcaccagatcctcgttctgttgtctgggttg
gaggaaaaaggaagcatctctctgacaggaagcagatcaaacttgggcttccagtcatcc
acactgctcacgtctgtgaggctgcagtttctagcagggtgttttggtttaggcactgtg
ggacatgcaggagccaaaggagagagtggccgattgcatcactatcaggatgggatcaga
gcagctaaaagaaatattcagattgaaatccaggtggctgtgcataagatttatcaacag
ttgtctgctaccctagagagagctctacaggcaaataagcatcacattgaagcccagcaa
cgtctccttttggttacagtttttgctctgagcgttcactatcaaccagtggatgtttct
ttggcaatttccactggtctgctaaacgtattgtcgcagttatgtggtacagacaccatg
ctgggacagcctctgcagttactgccaaagacgggtgtttctcagcttagtacagcttta
aaagtggctagtacaagattgctccaaattctagctatcactacagggacttacgctgat
aaactgagccccaaagtagttcagtccttgttggatctactctgtagtcagttgaagaat
ttgttgtcccaagctggtgtactacttatggcctcttttggagaaggggaaggagaagag
ggtgaagaagaagaaagaaaagttgactccagtggagaaactgagaagagagatttcaga
gctgctcttaggaaacaacatgcagcagaactgcatctgggggattttttagtttttctt
cgcagagttgtatcttcaaaagcaattcaatcaaaaatggcttccccaaaatggacagag
gtgcttctaaacatagcatctcagaagtgttcttcaggtattcctctcgttggtaaccta
agaacaaggctccttgcacttcatgtccttgaggctgtgctaccagcttgtgaatctggc
gtagaagatgatcaaatggctcaggttgttgaacgcctcttttcccttctgtcggactgt
atgtgggagacacccattgctcaggccaaacatgctattcagataaaggaaaaagaacaa
gaaataaagttacagaagcagggagagttagaggaagaagatgagaatcttcctatacaa
gaagtatcctttgatccagagaaagctcagtgttgtctagtggagaatggacagatttta
actcatggcagtggaggaaaaggatatggattggcatcaactggagtaacttctggatgc
tatcagtggaagttttacattgtgaaggaaaacagaggtaatgaaggcacgtgtgttgga
gtttctcgctggccagtacatgactttaaccaccgtactacctccgatatgtggctgtac
cgggcctacagtggtaacctctatcacaatggagaacagactctgacgttgtccagtttt
actcaaggagatttcattacctgtgtgttagacatggaagccagaaccatttcctttggg
aaaaatggagaggaacccaaattggcttttgaagatgtggacgcggcagagttatacccg
tgtgtaatgttctatagtagcaacccaggggagaaggtgaaaatttgtgatatgcaaatg
cgtggcacgccacgagacttacttccaggagaccctatttgtagtccagtagcagcagtg
ctggcggaggccactattcagcttatccgtatccttcaccgaacagaccgttggacttac
tgcattaacaaaaaaatgatggaaaggctgcataaaattaagatatgtattaaagagtca
ggtcagaagctaaagaaaagccgctcggttcaaagccgagaggaaaatgaaatgagagag
gagaaggaaagcaaagaggaagagaaaggtaaacataatagacatggccttgctgacctc
tcagagccgcagctgaggaccctttgcatagaggtgtggcctgtgctggcagtgatagga
ggagttgatgctggtcttagagttggaggtcggtgtgttcacaagcaaactgggcgccat
gccacgctgctgggagtggtcaaagagggcagcacgtctgctaaggtccaatgggatgaa
gcagaaattaccatcagcttcccaactttttggtcgcctagtgatactccattgtataat
ctggagccctgtgaaccattgccttttgatgtggcgcgattccgaggcctgacggcttct
gtgttgctggacctcacatatctgactggtattcatgaagacatgggcaaacagagcacc
aagcgacatgaaaagaaacaccgacatgagtctgaggagaaaggagatgttgagcagaaa
accgagaatgaatctgctttagatacgcgaacaggcttaacatctgatgatgtcaaaaat
cagggtaccacagcctccaaatccgaaaacgaaatagcttcattttctttagacccaaca
ctgccaagtgtggaatcccaacatcagataacagaaggaaaaagaagaaatcacgaacac
atatccaaaaaccatgacatagcccaatcagaaatcagagcagtccaactgtcctatctc
tacctcggtgctatgaaatcacttagtgctcttcttggctgtagtaaatatgctgagctg
ttgctgataccaaaagttctggctgaaaatggccataactcagactgtgcaagctctcca
gttgttcatgaagatgtggagatgcgagcagccttgcagttcctgatgcgacacatggtg
aagcgagccgtcatgcggtcgcccataaagagagcgttgggattagctgatttggaacga
gctcaagccatgatctacaaattagtggtccatgggctcctggaagaccagtttgggggc
aaaattaagcaagagattgatcaacaagctgaagaaagtgaccaagcccagcaggcacaa
acaccagttaccactagcccatcagcctcgagcacaacttcctttatgagcagctcgctg
gaagacaccacaactgccaccactccagtcactgacacagaaacagtacctgcatctgaa
tccccaggagtgatgccacttagtcttctcaggcaaatgttctctagttacccaactacc
actgtacttcccacacgtcgtgcacagactcctccaatatcatcattaccaacctctcct
tctgatgaagtaggaagaaggcaaagcttaacttctcctgattcccagtcagcaaggcca
gctaaccgcacagccttgtcagacccaagcagcagactttcaacttctcctcctcctcca
gcaattgcagtacccttgctggagatggggttctctctccggcagattgccaaagccatg
gaagccacaggtgctcgaggagaggctgatgcccagaacatcactgtccttgccatgtgg
atgatagagcaccctgggcatgaggatgaggaggaaccccagccaggcagcacagctgac
tcaagacacggagcagctgtcctaggcagtggtgggaaatcaaatgatccctgttatttg
cagtcaccaggagacataccatcagctgatgctgctgaaatggaagaaggctttagtgaa
agcgctgataatctggaccatgcagagaatgcagcttctggaagtggaccaccagctagg
ggtcgctcagcagtaacaagaaggcacaagtttgatttagctgctcgcacattgctagca
agagcagcggggttataccgctctgtgcaggcccacaggaatcaaagtcggagagaagga
atatctttgcaacaagacccaggggcgttgtatgactttaatttagatgaggaattggaa
attgatcttgatgatgaagcaatggaagctatgtttggacaagacctgaccagtgacaat
gatattctgggaatgtggatcccagaggtactggattggcctacctggcatgtttgtgag
tctgaagacagggaagaagtggtggtgtgtgaactgtgtgagtgcagtgtcgtcagcttc
aaccagcacatgaagagaaatcacccaggctgtgggcgcagtgcaaaccgccagggctat
cgcagcaacggctcctatgtggatggctggttcggtggtgaatgtgggagtggaaatcca
tactacctgctctgcggcagctgcagggaaaagtacttagccctgaagaccaaatccaag
acaacaagttctgaaaggtacaagggacaagctccagatctaattggcaagcaggacagt
gtgtatgaagaagactgggacatgttagatgttgatgaagatgaaaagctaacaggtgaa
gaagaatttgaattacttgctggaccacttggtttaaacgaccgacgcattgtaccagaa
ccagttcagttccctgacagtgatcccttgggagcatcagtagcaatggtaacagctacc
aacagtatggaagagactctaatgcaaataggttgccatggctctgtagaaaagagttcc
tctggaagaataacactaggtgagcaggccgctgccttagcaaaccctcatgaccgggtg
gtggctttaaggagagtgactgctgctgctcaggttcttctggcaagaaccatggtaatg
agagctctgtctcttctctcggtcagtggttccagctgtagcctggctgctggcctggaa
tctctggggcttacagatatccgaacactggttcggttaatgtgcttggccgcagcaggg
agagctggcctttctaccagcccttctgccatggcaagcacctcagaacgctcacgaggc
gggcacagcaaggccagtaagcccatctcttgcctggcctatctgagcacagcagtggga
tgtctggcatcaaacactcctagtgctgccaaactcctggtgcagttgtgtacacagaac
ttgatttctgctgcaacaggtgtaaatctaaccacggtcgatgatccaattcagcgaaag
tttctacccagctttctccgaggaattgctgaagagaataagcttgtaacctccccaaac
tttgttgtaactcaggcccttgtggcattactagcagacaagggggccaaactgagacct
aactatgataaatctgaagttgaaaagaaaggtttaactgcccaattgtatgcccatcct
tcctatgatccttctgctgtaggccctctggagctggctaatgccctggcagcctgctgc
ctctcctccaggctgtcctcacagcataggcaatgggctgctcaacagcttgtgcgcact
cttgctgcacatgaccgcgacaaccaaactactccccaaacactcgctgatatgggagga
gatctcaggaaatgctcctttatcaagttggaggctcatcaaaacagagtgatgacttgt
gtttggtgtaataaaaaaggacttttggctacaagtggcaatgatggtaccatccgggta
tggaatgttactaagaagcaatattcactgcaacaaacctgtgtgttcaacagattagaa
ggagatgctgaggagagcctggggtcacccagtgatccaagtttctcacctgtttcctgg
agtatcagtggcaaatatctagctggggccttggaaaagatggtgaatatttggcaagtt
aatggaggtaaaggattagtagatattcagcctcattgggtatctgccctggcttggcca
gaagagggtccagctacagcctggtcaggagagtctccagaattattgttggtgggacgg
atggatggctctctaggactgatagaagttgttgatgtatccactatgcactgtcgagaa
ttggaacattgctatcgaaaagatgtgtctgtaacttgcattgcttggttcagtgaagac
agaccatttgcagtaggattttttgatggaaaattgttactgggaacgaaggaaccactt
gagaaaggaggcattgttctaattgatgcacataaggatactcttgttagtatgaagtgg
gacccaacaggtcatattcttatgacatgtgccaaagaagaaaatgtgaaactctggggg
cctatttcaggatgctggcgctgtctacattcactctgccatccatctattgtaaatggc
attgcttggtgcagcctcccagggaaaggatccaaattgcatttactgatggctactggc
tgtcagagtggcttggtatgtgtttggcgtattccacaagataccacacagaccagtgtg
actagttcagaaggatggtgggaccaggagtcaaattgccaggatggatataggaaatca
gccggagccaaatgtgtttatcagctgcggggacacatcacccctgtccggactgttgcc
tttagttctgatgggttggccctcgtgtctggtggactaggtgggctcatgaacatttgg
tctttaagggatggctctgtcttgcaaactgtagtgataggctctggagctattcagacc
acagtatggattccagatgttggggtagctgcttgctcaaatagatcgaaggatgttttg
gtcgtgaattgtacagcagaatgggctgccgccaatcatgttttagcaacctgtaggaca
gcactgaaacagcagggtgttctgggattaaatatggctccctgcatgagagcatttctg
gagcggctacccatgatgcttcaggagcagtatgcctatgaaaagcctcatgtggtttgt
ggcgatcagcttgttcatagcccctatatgcaatgtctggcttccctcgctgtgggactg
catttggatcagctgttatgtaaccctccagtgccaccacaccaccagaactgcctccct
gacccagcatcctggaatccaaatgagtgggcctggttagaatgtttctcaaccaccata
aaagctgctgaagccctgaccaacggagcacaatttccagaatcttttaccgttcctgat
ctagagcctgttccagaggatgagcttacattcctaatggataacagtaaatggattaat
ggcatggatgaacaaattatgtcttgggcaacatccagacctgaggactggcacttggga
ggtaaatgtgatgtctacctgtggggtgctggcaggcatggacagcttgccgaagctgga
agaaatgttatggtacctgcagcagctccctcattctcacaggcccaacaggtcatatgt
ggtcagaattgtacctttgtcatccaggccaatggcacagtgttggcttgtggggaagga
agttatggcagattggggcaaggaaattcagatgaccttcatgtgctgacagttatttca
gccttacaaggatttgtggtgacccagctggtgacatcttgtggttctgatggtcactca
atggccctgactgaaagtggtgaggtctttagctggggagatggcgattatggcaaactc
ggccacgggaacagcgacaggcagcggcgccccaggcagatcgaggccttacaaggagaa
gaagtggtgcagatgtcttgtggcttcaagcactcagcagtggtaacttcagacggcaaa
ctgttcacttttgggaatggtgactatggtcgtctgggtcttggaaacacctctaacaaa
aaactaccagagagagtgactgcactggagggatatcagattggacaggtggcttgtggt
ttaaaccacactttggcagtatcagcagatggctccatggtgtgggcttttggagacggg
gactatggaaaactaggcttaggaaattccactgcaaaatcttcccctcagaaagttgat
gtcctttgtggaattggaataaaaaaggttgcttgtggaactcagttttctgttgcatta
accaaagatggtcatgtgtatacctttggtcaagatcgcttgataggcttgccagagggg
cgtgctcgcaatcataaccgaccacagcagatccctgtgctggctggagtggtcatcgaa
gatgtggcggttggagctgagcacactcttgctttggcatcaactggagatgtgtatgcc
tgggggagcaattcagaagggcagcttggcttaggccacaccaaccatgttcgagaacca
accctggtaacagtcctgcaagggaaaaatgtccggcagatctcagctggccgctgccac
agtgctgcatggacagcgccacctgtcccgccaagagcacccggtgtgtcggtacctctg
cagctgggcctgcccgatgcggtccccccccagtatggggcgttgagggaggtgagcatt
cacactgcgagggccaggctccggctgctctaccatttctctgacctcatgtactcatcc
tggaggctactgaacctcagccccaacaaccagaacagtacatctcattataatgctgga
acatggggcattgtacagggacagcttcggcctttgttagctccaagggtctacaccctg
ccaatggtgcgctccatagggaaaaccatggttcaaggcaaaaactatggacctcaaatt
actgtgaagaggatatcaaccagaggacggaagtgtaagcccatctttgtccagatagca
agacaagtagttaagctgaatgcatcagacctccgtctgccctcacgagcgtggaaggtt
aagctggttggtgaaggggcggatgatgctgggggagtgtttgatgacacgatcacagag
atgtgccaggaacttgaaactggtattgttgaccttcttataccctctcccaatgctact
gcagaagtgggctacaatagggataggttcctttttaacccctctgcctgccttgacgaa
cacttaatgcagtttaagttcttagggatcttgatgggggttgccattcgcacaaagaag
cctctggacctccacttggcccctttggtgtggaagcagctgtgctgtgtcccactcacc
ctagaagacctggaggaggtggatctgctctacgtgcagaccctcaacagcattcttcac
attgaagacagtgggattaccgaggaaagtttccatgagatgattcctcttgattctttt
gttggccaaagtgctgatggcaaaatggttcccataatccctggtggaaatagtatccca
ctgacattttccaacaggaaggagtatgtggagagggccattgaatatcgacttcatgag
atggaccgacaggtggctgcagtccgagaagggatgtcctggatcgtccctgtgccgctg
ctgtccctcctcacggcaaagcagctggagcagatggtgtgtgggatgcccgagatctct
gtggaagttctgaagaaagtggtgcggtaccgggaggtggacgagcagcaccagctggtg
cagtggttctggcacacgctggaggagttctcgaacgaggagcgggtgcttttcatgagg
tttgtgtctggaagatctcgactaccagccaacactgctgacatttctcagagatttcaa
atcatgaaggttgataggccttatgacagtctgcctacctcacagacctgcttcttccag
ctgcggctgcccccctactccagccagctggtcatggccgagcgcctgcgctatgccatc
aacaactgccgctccatcgacatggacaactacatgctctcgcggaacgtggacaacgcc
gagggctccgacaccgactactga

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