Panthera pardus (leopard): 109263110 Help Entry 109263110         CDS       T06062                                  Symbol PLA2G4D Name (RefSeq) cytosolic phospholipase A2 delta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ppad  Panthera pardus (leopard) Pathway ppad00564   Glycerophospholipid metabolism ppad00565   Ether lipid metabolism ppad00590   Arachidonic acid metabolism ppad00591   Linoleic acid metabolism ppad00592   alpha-Linolenic acid metabolism ppad01100   Metabolic pathways ppad04010   MAPK signaling pathway ppad04014   Ras signaling pathway ppad04072   Phospholipase D signaling pathway ppad04217   Necroptosis ppad04270   Vascular smooth muscle contraction ppad04370   VEGF signaling pathway ppad04611   Platelet activation ppad04664   Fc epsilon RI signaling pathway ppad04666   Fc gamma R-mediated phagocytosis ppad04724   Glutamatergic synapse ppad04726   Serotonergic synapse ppad04730   Long-term depression ppad04750   Inflammatory mediator regulation of TRP channels ppad04912   GnRH signaling pathway ppad04913   Ovarian steroidogenesis ppad04921   Oxytocin signaling pathway ppad05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     109263110 (PLA2G4D)    00565 Ether lipid metabolism     109263110 (PLA2G4D)    00590 Arachidonic acid metabolism     109263110 (PLA2G4D)    00591 Linoleic acid metabolism     109263110 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     109263110 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109263110 (PLA2G4D)    04014 Ras signaling pathway     109263110 (PLA2G4D)    04370 VEGF signaling pathway     109263110 (PLA2G4D)    04072 Phospholipase D signaling pathway     109263110 (PLA2G4D)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     109263110 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109263110 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     109263110 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     109263110 (PLA2G4D)   09152 Endocrine system    04912 GnRH signaling pathway     109263110 (PLA2G4D)    04913 Ovarian steroidogenesis     109263110 (PLA2G4D)    04921 Oxytocin signaling pathway     109263110 (PLA2G4D)   09153 Circulatory system    04270 Vascular smooth muscle contraction     109263110 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     109263110 (PLA2G4D)    04726 Serotonergic synapse     109263110 (PLA2G4D)    04730 Long-term depression     109263110 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109263110 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109263110 (PLA2G4D) Enzymes [BR:ppad01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      109263110 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 STAT_linker YscJ_FliF Motif Other DBs NCBI-GeneID:  109263110 NCBI-ProteinID:  XP_019298013 Ensembl:  ENSPPRG00000013503 UniProt:  A0A9V1F961 LinkDB All DBs Position Unknown AA seq 814 aa AA seqDB search MERLTTRGPPGHPHQVEASACWRLTVKVLEARNLGWADLLSEADPYVTLQLPTAPGTKFK TKTITNSSHPVWNETFSFLIQSRVKNILELNVYDEDPVTEDDACFKILYDVSEVLPGQLL QKTFSLRPQGQEELDVEFLMEKMSERPENLITNNVLVARELSCLDVHLVSIGSTATVTDQ DELELVLKGSYEDTQTSALGTASFRFHYMAAQEAELSGHLKRLERNAWNSDKSAEHLTVP LRSLAMGKEVTINVPATNAPEVTLQLKTEGCPKELAMHLGFDLCAEEKAFLSRRKQVVAK ALKQVLQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGS TWTMAHLYGDPEWSQGDLEGPIKCAREHLAKSKLEAFSPERLASYCRELELRAKQGHPKT FVDLWALVLESMLHGQVMDQKLSEQRAALERGQNPLPLYLSLNVKENHLETLDFKEWVEF SPYEVGFLKYGAFVPSDLFGSEFFMGRLMRKLPESRICFLEGIWSNVLSLNLLDAWYDLI SSDDTWKQHVKDKIKNLEESPASMRTSSWLEASWLQPGTMLAKAFKGFLTGRPLHQHSLN FLRGLQLHQDYYSQRDFSTWADCELDSTPGQLTPQEPQLCLVDGGYFLNTSCPSMFRPGR RLDLILSFDYSLSSPFKTLQQTELYCRAQGLPFPRVDPNPQDQHQPTECHLFSDPTHPDT PVLLHFPLVNASFKDHSAPGVLRSPTELPAGQVDLTGTASPYSLFNMTYKEEDFDRLLQL SDYNVRNSQDAILQALRMAMKHRALGARPPTAQN NT seq 2445 nt NT seq  +upstreamnt  +downstreamnt atggaaagactgacaactaggggaccacctggccatcctcaccaggtggaggcctctgct tgctggcggcttactgtgaaggtcctggaggccaggaacctgggctgggctgacctgttg agtgaggcagacccctacgtgaccctacagctgcccactgcacctgggacaaagtttaaa accaaaacaatcaccaactccagtcatcctgtatggaatgagaccttcagtttcctgatc cagagtcgggtcaagaatattctggagctaaacgtctatgatgaggacccagtcacggag gatgatgcctgcttcaagattctctatgatgtctcagaagtcctccctggccagctgctc cagaagaccttctccctgcgtccccagggacaggaggagctggacgtggagttcctaatg gaaaaaatgtcagaacgcccagaaaacctcatcaccaacaacgtccttgtggcccgagag ctgtcatgcctggatgtccatctggtcagcattgggagcacagccacggtcacagatcag gatgagctggagttggtgctgaagggctcatatgaagacacacagacctctgcactaggc acagcatccttccgcttccattacatggcagcccaagaggcagaactgagtgggcatctg aagaggttggaaaggaatgcctggaattcagacaagtcagctgagcacctcactgtgcct ctaaggtccttggccatgggaaaggaggtgaccattaacgttcctgctacaaacgcccca gaagtgacactgcagctcaagactgagggctgccctaaggagctggctatgcacctgggc tttgatctgtgtgcagaggagaaagctttcctgagcaggaggaagcaggtggtggccaag gctctcaagcaggtcttgcagctggacagagacctacaggaggatgaggtccctgttgtg ggcataatggccacaggaggaggtgcccgggccatgacgtctctctacggccacctgttg gccctacagaagctgggcctcctggactgtgtgacctacttcagtggcatctcaggctct acatggacaatggcccacctctacggggacccggagtggtcacagggggacctcgaagga cccatcaaatgtgctagagagcacctggccaagagcaaactggaggccttctccccagag cgcctagcaagctactgccgggagctggagctgcgggctaagcagggccaccccaagacc tttgtggacctgtgggctctcgtgctggagtccatgctgcatggccaggtgatggatcag aagctgtcagaacagagagctgcactggagcggggccagaaccctctgcccctctacttg agcctcaatgtcaaagagaaccatctggagaccctggacttcaaggagtgggtagagttt tcaccctatgaagtggggttcctgaagtatggagcctttgtcccttctgatctctttggc tctgagttcttcatggggcggctgatgaggaagctccctgagtcccggatctgctttctg gaaggtatctggagcaacgttttgtccctgaacttgctggatgcctggtatgacctcatc agctctgatgacacctggaagcagcatgtcaaggacaaaattaagaacctggaggagtct cctgcctccatgaggacctcctcgtggctggaggcctcatggctgcaacccggaacaatg ctggccaaggcatttaagggcttcctgacaggcaggccgctccaccagcatagcctcaac ttccttcggggcctccagctgcaccaggactactatagccagagagacttctccacctgg gcagactgtgagctagactccacccctggccagcttacgcctcaggagccacagctctgc ctggtagatggcggctacttcctcaacaccagctgtccctccatgttccggccaggccgc agactggacctcatactctccttcgactactccctatcctcaccctttaagacgctgcag cagactgagctgtactgccgggcccagggactgccattccctcgagtggaccccaaccct caggaccaacaccagccaacagagtgccacctcttctcggaccccactcaccctgatacc cctgtcctgctgcacttcccactggtcaatgcctccttcaaggaccactcagcccctggt gtcctacgcagccccacagaactcccagctggccaggtggatctcactgggaccgcctca ccctattccctattcaacatgacctacaaggaggaagattttgatcgcctgctgcagctt agtgactacaatgtacggaacagccaggatgccattctgcaggccttgaggatggccatg aaacaccgggccctgggggccagacctccaacagcacagaattga

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