Panthera pardus (leopard): 109264323
Help
Entry
109264323 CDS
T06062
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00760
Nicotinate and nicotinamide metabolism
ppad01100
Metabolic pathways
ppad04068
FoxO signaling pathway
ppad04148
Efferocytosis
ppad04152
AMPK signaling pathway
ppad04211
Longevity regulating pathway
ppad04213
Longevity regulating pathway - multiple species
ppad04218
Cellular senescence
ppad04310
Wnt signaling pathway
ppad04922
Glucagon signaling pathway
ppad04936
Alcoholic liver disease
ppad05031
Amphetamine addiction
ppad05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
109264323 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
109264323 (SIRT1)
04068 FoxO signaling pathway
109264323 (SIRT1)
04152 AMPK signaling pathway
109264323 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109264323 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
109264323 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109264323 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
109264323 (SIRT1)
04213 Longevity regulating pathway - multiple species
109264323 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109264323 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
109264323 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109264323 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ppad03036
]
109264323 (SIRT1)
03029 Mitochondrial biogenesis [BR:
ppad03029
]
109264323 (SIRT1)
Enzymes [BR:
ppad01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
109264323 (SIRT1)
Chromosome and associated proteins [BR:
ppad03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
109264323 (SIRT1)
Mitochondrial biogenesis [BR:
ppad03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
109264323 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
109264323
NCBI-ProteinID:
XP_019299871
Ensembl:
ENSPPRG00000013011
UniProt:
A0A9W2UDX8
LinkDB
All DBs
Position
Unknown
AA seq
779 aa
AA seq
DB search
MEFWIESPSRGGASAASRAGAEEAREEGQRGSWKMADEAALALQPGGSPSAVVAEREAAS
PPAGEPLRKRPRRDCPGLGRSPGEPGGAAPEREVPAATGGCPAAAAALWREAAAAGEERE
AQAATAGEGDNGPGLQGLTREPPPADDFYDDDDDDDEGEEEEEAAAAAAIGYRDNLLFGD
EIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETI
PPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGI
PDFRSRDGIYARLAIDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFI
ALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQ
VVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVAL
IPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEI
TEKPPRTQKELAHLSELPPTPLNISEDSSSPERTSPPDSSVIVTLLDQATKSNVNDSEVS
EPRDHMEEKSQEGQNSTRNIDSVTEQLGSPDSKNVDSNTGEKNERTSIAETVRKCWPARL
AKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEH
LEDESEIEEFYNGLEDDADVNERAGGTGFGVDGGDQEAVNEAISMKQEATDINYPSNKS
NT seq
2340 nt
NT seq
+upstream
nt +downstream
nt
atggaattttggattgaaagcccgagccgcgggggcgccagtgccgcgagtcgagcggga
gcagaggaggcgagggaggagggccagagaggcagttggaagatggcggacgaggcggcg
ctcgcccttcagcccggcggctccccctcggcggtggtggccgagagggaggccgcgtcg
ccgcccgccggagagccactccgcaagaggccgcggagagactgtccaggcctggggcgg
agcccgggcgagcccggtggggcggcccccgagcgtgaagtgccggcggcgaccgggggc
tgccccgcggcggccgcggcgctgtggcgggaggcggcagcggcgggcgaggagcgggag
gcccaggcggcgacggccggagaaggagacaatgggccgggcctacagggcctaacccgg
gagccgccgccggccgacgacttctacgacgacgacgacgacgacgacgagggcgaagag
gaggaagaggcggcggcggcggcggcgattgggtaccgagataaccttctgtttggtgat
gaaataatcaccaatggttttcattcctgtgaaagtgatgaggatgatagagcctcacat
gcaagttctagcgactggactccaaggccacgtataggtccatatacttttgttcagcag
catctcatgattggcacagatcctcgaacaattcttaaagatttattaccagaaacaatt
cctccacctgaattggatgatatgacactgtggcagattgttattaatatcctttcagaa
ccaccaaaaaggaaaaaaagaaaagatattaatacaattgaagatgctgtgaaattatta
caagagtgcaaaaaaataatagttctaactggagctggggtttctgtttcttgtggaata
cctgacttcaggtcaagagatggtatttatgctcgccttgcaatagacttcccagacctt
ccagaccctcaagcaatgtttgatattgaatatttcagaaaagatccaagacctttcttc
aagtttgcaaaggaaatatatcctggacagttccaaccatctctctgtcacaaattcata
gccttgtcagataaggaaggaaaactgcttcggaactatactcagaacatagatacactg
gaacaggttgcaggaatccaaaggataattcagtgtcatggttcctttgcaacagcctct
tgcttgatttgtaaatacaaagtagactgtgaagctgtacgaggagatatttttaatcag
gtggttcctcgttgtcctaggtgcccagctgatgaaccacttgctatcatgaaaccagag
attgtcttttttggtgaaaatttaccagagcagtttcatagagccatgaagtatgacaaa
gatgaagttgatctccttattgttattgggtcttccctgaaagtaagaccagtagcacta
attccaagttccataccccatgaagtgcctcagatactaataaatagagaacctttgcct
catctgcattttgatgtagagcttcttggagactgtgatgtcataattaatgaattatgt
cataggttaggtggtgaatatgccaaactttgctgcaaccctgtaaagctttcagaaatt
actgaaaaacctccacgaacacaaaaagagttggctcatttgtcagagttgccacccaca
cctcttaatatttcagaagactcaagttcaccagaaagaacttcaccaccagattcttca
gtgattgttacacttttagaccaagcaactaagagcaatgttaatgattctgaggtgtct
gaaccaagagatcatatggaagaaaaatcacaggaaggacagaattctactaggaacatt
gacagtgttactgaacagctgggaagtccggattcgaagaatgttgactctaatactggg
gaaaaaaatgaaagaacttcaattgctgaaacagtgaggaagtgctggccagctagactt
gcaaaggagcagattagcaaacggcttgatggtaatcagtatctgtttttaccaccaaat
cgttatattttccatggcgctgaggtatattcagactctgaagatgacgtgttatcctct
agttcttgtggcagtaacagtgatagtggaacatgccagagtccaagtttagaagaacac
ttggaggatgaaagtgagattgaagaattttacaacggtttggaagacgatgctgatgtt
aatgagagagctggaggaactggatttggagttgatggaggtgatcaagaggcagttaat
gaagctatatccatgaaacaggaagcaacagacattaactatccatcaaacaaatcataa
DBGET
integrated database retrieval system
