KEGG   Panthera pardus (leopard): 109265419
Entry
109265419         CDS       T06062                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad01521  EGFR tyrosine kinase inhibitor resistance
ppad01522  Endocrine resistance
ppad04010  MAPK signaling pathway
ppad04014  Ras signaling pathway
ppad04015  Rap1 signaling pathway
ppad04066  HIF-1 signaling pathway
ppad04068  FoxO signaling pathway
ppad04081  Hormone signaling
ppad04114  Oocyte meiosis
ppad04115  p53 signaling pathway
ppad04150  mTOR signaling pathway
ppad04151  PI3K-Akt signaling pathway
ppad04152  AMPK signaling pathway
ppad04211  Longevity regulating pathway
ppad04213  Longevity regulating pathway - multiple species
ppad04510  Focal adhesion
ppad04550  Signaling pathways regulating pluripotency of stem cells
ppad04730  Long-term depression
ppad04750  Inflammatory mediator regulation of TRP channels
ppad04913  Ovarian steroidogenesis
ppad04914  Progesterone-mediated oocyte maturation
ppad04935  Growth hormone synthesis, secretion and action
ppad04960  Aldosterone-regulated sodium reabsorption
ppad05200  Pathways in cancer
ppad05202  Transcriptional misregulation in cancer
ppad05205  Proteoglycans in cancer
ppad05214  Glioma
ppad05215  Prostate cancer
ppad05218  Melanoma
ppad05224  Breast cancer
ppad05410  Hypertrophic cardiomyopathy
ppad05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109265419 (IGF1)
   04014 Ras signaling pathway
    109265419 (IGF1)
   04015 Rap1 signaling pathway
    109265419 (IGF1)
   04066 HIF-1 signaling pathway
    109265419 (IGF1)
   04068 FoxO signaling pathway
    109265419 (IGF1)
   04151 PI3K-Akt signaling pathway
    109265419 (IGF1)
   04152 AMPK signaling pathway
    109265419 (IGF1)
   04150 mTOR signaling pathway
    109265419 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109265419 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    109265419 (IGF1)
   04115 p53 signaling pathway
    109265419 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109265419 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    109265419 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    109265419 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    109265419 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    109265419 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    109265419 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    109265419 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109265419 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    109265419 (IGF1)
   04213 Longevity regulating pathway - multiple species
    109265419 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109265419 (IGF1)
   05202 Transcriptional misregulation in cancer
    109265419 (IGF1)
   05205 Proteoglycans in cancer
    109265419 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    109265419 (IGF1)
   05218 Melanoma
    109265419 (IGF1)
   05215 Prostate cancer
    109265419 (IGF1)
   05224 Breast cancer
    109265419 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    109265419 (IGF1)
   05414 Dilated cardiomyopathy
    109265419 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109265419 (IGF1)
   01522 Endocrine resistance
    109265419 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ppad04052]
    109265419 (IGF1)
Cytokines and neuropeptides [BR:ppad04052]
 Cytokines
  Growth factors (RTK binding)
   109265419 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 109265419
NCBI-ProteinID: XP_019302154
Ensembl: ENSPPRG00000000922
UniProt: A0A9V1FG92
LinkDB
Position
Unknown
AA seq 187 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSPSHLFYLGLCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYHPPSTTKKTKSQRRRKGGPKKHPGGEQKVGTEASQQMKGKKKEQR
RETGARN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtccccctctcatctcttctatctgggcctgtgcttgctc
accttcaccagctctgccacagctggaccagagacgctctgtggggctgagttggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggcggctagagatgtactgtgcacccctcaagcctgccaagtctgcccgctca
gtccgtgctcagcgccacactgacatgcccaaggctcagaagtatcatcccccatctacc
accaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacacccaggaggg
gagcagaaggtggggacggaagcaagtcagcagatgaaaggaaagaagaaagagcagaga
agggagactggagctagaaactga

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