Panthera pardus (leopard): 109265500
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Entry
109265500 CDS
T06062
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01521
EGFR tyrosine kinase inhibitor resistance
ppad01522
Endocrine resistance
ppad04010
MAPK signaling pathway
ppad04012
ErbB signaling pathway
ppad04014
Ras signaling pathway
ppad04062
Chemokine signaling pathway
ppad04068
FoxO signaling pathway
ppad04072
Phospholipase D signaling pathway
ppad04150
mTOR signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad04510
Focal adhesion
ppad04540
Gap junction
ppad04630
JAK-STAT signaling pathway
ppad04650
Natural killer cell mediated cytotoxicity
ppad04660
T cell receptor signaling pathway
ppad04662
B cell receptor signaling pathway
ppad04664
Fc epsilon RI signaling pathway
ppad04714
Thermogenesis
ppad04722
Neurotrophin signaling pathway
ppad04810
Regulation of actin cytoskeleton
ppad04910
Insulin signaling pathway
ppad04912
GnRH signaling pathway
ppad04915
Estrogen signaling pathway
ppad04917
Prolactin signaling pathway
ppad04926
Relaxin signaling pathway
ppad04935
Growth hormone synthesis, secretion and action
ppad05034
Alcoholism
ppad05160
Hepatitis C
ppad05161
Hepatitis B
ppad05163
Human cytomegalovirus infection
ppad05165
Human papillomavirus infection
ppad05200
Pathways in cancer
ppad05205
Proteoglycans in cancer
ppad05206
MicroRNAs in cancer
ppad05207
Chemical carcinogenesis - receptor activation
ppad05208
Chemical carcinogenesis - reactive oxygen species
ppad05210
Colorectal cancer
ppad05211
Renal cell carcinoma
ppad05213
Endometrial cancer
ppad05214
Glioma
ppad05215
Prostate cancer
ppad05220
Chronic myeloid leukemia
ppad05221
Acute myeloid leukemia
ppad05223
Non-small cell lung cancer
ppad05224
Breast cancer
ppad05225
Hepatocellular carcinoma
ppad05226
Gastric cancer
ppad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109265500 (SOS1)
04012 ErbB signaling pathway
109265500 (SOS1)
04014 Ras signaling pathway
109265500 (SOS1)
04630 JAK-STAT signaling pathway
109265500 (SOS1)
04068 FoxO signaling pathway
109265500 (SOS1)
04072 Phospholipase D signaling pathway
109265500 (SOS1)
04151 PI3K-Akt signaling pathway
109265500 (SOS1)
04150 mTOR signaling pathway
109265500 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109265500 (SOS1)
04540 Gap junction
109265500 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109265500 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
109265500 (SOS1)
04660 T cell receptor signaling pathway
109265500 (SOS1)
04662 B cell receptor signaling pathway
109265500 (SOS1)
04664 Fc epsilon RI signaling pathway
109265500 (SOS1)
04062 Chemokine signaling pathway
109265500 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
109265500 (SOS1)
04912 GnRH signaling pathway
109265500 (SOS1)
04915 Estrogen signaling pathway
109265500 (SOS1)
04917 Prolactin signaling pathway
109265500 (SOS1)
04926 Relaxin signaling pathway
109265500 (SOS1)
04935 Growth hormone synthesis, secretion and action
109265500 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
109265500 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
109265500 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109265500 (SOS1)
05206 MicroRNAs in cancer
109265500 (SOS1)
05205 Proteoglycans in cancer
109265500 (SOS1)
05207 Chemical carcinogenesis - receptor activation
109265500 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
109265500 (SOS1)
05231 Choline metabolism in cancer
109265500 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
109265500 (SOS1)
05225 Hepatocellular carcinoma
109265500 (SOS1)
05226 Gastric cancer
109265500 (SOS1)
05214 Glioma
109265500 (SOS1)
05221 Acute myeloid leukemia
109265500 (SOS1)
05220 Chronic myeloid leukemia
109265500 (SOS1)
05211 Renal cell carcinoma
109265500 (SOS1)
05215 Prostate cancer
109265500 (SOS1)
05213 Endometrial cancer
109265500 (SOS1)
05224 Breast cancer
109265500 (SOS1)
05223 Non-small cell lung cancer
109265500 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
109265500 (SOS1)
05160 Hepatitis C
109265500 (SOS1)
05163 Human cytomegalovirus infection
109265500 (SOS1)
05165 Human papillomavirus infection
109265500 (SOS1)
09165 Substance dependence
05034 Alcoholism
109265500 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109265500 (SOS1)
01522 Endocrine resistance
109265500 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
109265500
NCBI-ProteinID:
XP_019302298
Ensembl:
ENSPPRG00000003762
UniProt:
A0A9V1FGL5
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENTQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFVQVSLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSIAD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLPSITGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaaccgatgaagagccttccacctcaggagagcaaact
tactatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattattttcagctaat
gacgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaaattactg
ggccatatagaagatactgtggaaatgactgatgaaggtagtccccatcccttagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatatcttacggcctggttttcatgatcgtttccttagtcagttatcaaagccaggagca
gcactctatttacagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctacttctagcccctgtttaccactgtctgcattactttgagcttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcaaaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaagcatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagagtatcgtctgaaagaaaagtttttcatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ctgatatctctccagtaccggagcacactggaaaggatgcttgacgtgacgatgctacag
gaagagaaggaggagcagatgaggctccctagtgctgatgtttatcgatttgcagagcct
gactccgaagagaatataatatttgaagagaacacacagcccaaggctggaattccaatt
atcaaagcaggaactgttattaagcttattgagaggctcacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaaggtttaggaaagaa
tacatacagcctgtacaactgcgagtattaaatgtatgtcggcattgggtagagcaccat
ttctatgattttgaaagagacgcagatcttttgcagcgaatggaagagtttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcaggcctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagcgtgtggacaaaagaagacaaagaaattaattctcctaat
ctcctaaaaatgatccggcacaccactaacctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tctcctgtttacagactagaccacacatttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgagttaagcgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccgtgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccttagaaatagaaccgcgaaac
cctaagcctctcccaagatttccaaaaaaatacagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttacagtaggatccccgaaagtgagacagaaagtacagcatctgcacca
aactctccaagaacaccgttaacacctcctcctgcttcgggtgcttctagtaccacagat
gtttgcagcgtatttgactctgatcattcgagcccttttcactcaagcagcgataccgtc
tttgtccaagtttcactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagggcactgacgaagtgcctgtcccccctcctgttcctccacgaagacggccagaa
tctgcccccgcggaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctagacagcccacatcaaaagcctattcaccgcggtattcaatagcagac
cggacctctatatcagaccctcccgagagccctcccttattaccaccgcgagaacctgtg
aggacacctgatgttttctccagctcaccactacatctccagcctccccctttgggcaaa
aaaagcgatcatggcaatgccttcttcccaaacagcccttccccatttacgccacctcct
cctcaaacaccttctcctcatggcacgagaaggcatctgccatcaccaccactgacacaa
gaagtggaccttccttccatcactgggccgccggttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttataaaagggagcacacacacccctccatgcac
agagatggaccaccactgttggagaacgcccattcttcctga
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integrated database retrieval system
