KEGG   Panthera pardus (leopard): 109265586
Entry
109265586         CDS       T06062                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04010  MAPK signaling pathway
ppad04022  cGMP-PKG signaling pathway
ppad04137  Mitophagy - animal
ppad04141  Protein processing in endoplasmic reticulum
ppad04151  PI3K-Akt signaling pathway
ppad04210  Apoptosis
ppad04211  Longevity regulating pathway
ppad04261  Adrenergic signaling in cardiomyocytes
ppad04668  TNF signaling pathway
ppad04720  Long-term potentiation
ppad04722  Neurotrophin signaling pathway
ppad04725  Cholinergic synapse
ppad04728  Dopaminergic synapse
ppad04911  Insulin secretion
ppad04912  GnRH signaling pathway
ppad04915  Estrogen signaling pathway
ppad04918  Thyroid hormone synthesis
ppad04922  Glucagon signaling pathway
ppad04925  Aldosterone synthesis and secretion
ppad04926  Relaxin signaling pathway
ppad04927  Cortisol synthesis and secretion
ppad04928  Parathyroid hormone synthesis, secretion and action
ppad04932  Non-alcoholic fatty liver disease
ppad04934  Cushing syndrome
ppad04935  Growth hormone synthesis, secretion and action
ppad05010  Alzheimer disease
ppad05012  Parkinson disease
ppad05014  Amyotrophic lateral sclerosis
ppad05020  Prion disease
ppad05022  Pathways of neurodegeneration - multiple diseases
ppad05030  Cocaine addiction
ppad05031  Amphetamine addiction
ppad05034  Alcoholism
ppad05161  Hepatitis B
ppad05163  Human cytomegalovirus infection
ppad05166  Human T-cell leukemia virus 1 infection
ppad05203  Viral carcinogenesis
ppad05207  Chemical carcinogenesis - receptor activation
ppad05215  Prostate cancer
ppad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    109265586 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    109265586 (ATF4)
   04022 cGMP-PKG signaling pathway
    109265586 (ATF4)
   04151 PI3K-Akt signaling pathway
    109265586 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    109265586 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    109265586 (ATF4)
   04922 Glucagon signaling pathway
    109265586 (ATF4)
   04915 Estrogen signaling pathway
    109265586 (ATF4)
   04926 Relaxin signaling pathway
    109265586 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    109265586 (ATF4)
   04918 Thyroid hormone synthesis
    109265586 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    109265586 (ATF4)
   04925 Aldosterone synthesis and secretion
    109265586 (ATF4)
   04927 Cortisol synthesis and secretion
    109265586 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    109265586 (ATF4)
   04728 Dopaminergic synapse
    109265586 (ATF4)
   04720 Long-term potentiation
    109265586 (ATF4)
   04722 Neurotrophin signaling pathway
    109265586 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    109265586 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    109265586 (ATF4)
   05203 Viral carcinogenesis
    109265586 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    109265586 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109265586 (ATF4)
   05161 Hepatitis B
    109265586 (ATF4)
   05163 Human cytomegalovirus infection
    109265586 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109265586 (ATF4)
   05012 Parkinson disease
    109265586 (ATF4)
   05014 Amyotrophic lateral sclerosis
    109265586 (ATF4)
   05020 Prion disease
    109265586 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    109265586 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    109265586 (ATF4)
   05031 Amphetamine addiction
    109265586 (ATF4)
   05034 Alcoholism
    109265586 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109265586 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    109265586 (ATF4)
   04934 Cushing syndrome
    109265586 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ppad03000]
    109265586 (ATF4)
Transcription factors [BR:ppad03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    109265586 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU KIF21A Asd-4 AAA_13 Nop53 bZIP_Maf DUF3450 Laminin_II OVT1
Other DBs
NCBI-GeneID: 109265586
NCBI-ProteinID: XP_019302483
Ensembl: ENSPPRG00000000736
UniProt: A0A9V1FGP9
LinkDB
Position
Unknown
AA seq 352 aa
MAEMMSFLSSEVLGGDLMSPFDQSGLGAEVSLGLLDDYLEVAKHFKPHGFSSDKAKAGSS
EWLAADGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFNIDDLETMPDELLATLDDT
CDLFDPLVQETNKEPPQTMNPIGHLPESLPKTDQVAPYTFLQPLSLSPGALSSTPDHSFS
LELGSEVDISEGDRKPDSTAYILMIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTS
RGSPSKSQLSPCNLCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1059 nt   +upstreamnt  +downstreamnt
atggccgagatgatgagcttcctgagcagcgaggtgttggggggggacttgatgtccccc
ttcgaccagtcgggtttgggggctgaagtaagcctaggtctcttagacgattacctggag
gtggccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctcc
gaatggctggctgcggatgggttggtcagtgcctcagacaacggcaaggaggatgccttc
tccgggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctg
ttcaatatagatgacctggaaaccatgccagatgagcttttggccactttggatgacaca
tgtgatctctttgaccccctagtccaggagacgaataaggagcccccccagaccatgaac
ccaattggccatctcccagaaagtttacccaaaacagaccaggttgccccttataccttc
ctgcaacctctttctctctccccaggggccctttcctccactccagatcattcctttagt
ttagagctaggcagtgaggtggatatctctgaaggagatagaaagccagactctactgct
tacattctcatgatcccacagtgcataaaggaggaggatgccccgtcagataatgatagc
ggcatctgtatgagtcctgagtcctatctggggtccccccagcatagcccctcgacttca
aggggctctccaagtaagagccagctgtctccatgtaacctctgtggttctgcccgcccc
aaaccctacgatccccctggagagaaaacggcagcaaaagtaaaggtggagaagttggat
aagaagctgaaaaaaatggagcagaacaagacagcagccactaggtaccgccagaagaag
agggcggagcaagaggcccttactggcgagtgtaaagagctagaaaagaagaatgaggct
ctgaaagagagggcagactctttggccaaggagatacaatatctgaaagatttgatagaa
gaggtccgaaaggccagggagaagaaaagggtcccctag

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