Panthera pardus (leopard): 109266499
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Entry
109266499 CDS
T06062
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04020
Calcium signaling pathway
ppad04022
cGMP-PKG signaling pathway
ppad04270
Vascular smooth muscle contraction
ppad04371
Apelin signaling pathway
ppad04510
Focal adhesion
ppad04611
Platelet activation
ppad04810
Regulation of actin cytoskeleton
ppad04921
Oxytocin signaling pathway
ppad04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
109266499 (MYLK)
04020 Calcium signaling pathway
109266499 (MYLK)
04022 cGMP-PKG signaling pathway
109266499 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109266499 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109266499 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109266499 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
109266499 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
109266499 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
109266499 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109266499 (MYLK)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
109266499 (MYLK)
Protein kinases [BR:
ppad01001
]
Serine/threonine kinases: CAMK group
MLCK family
109266499 (MYLK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
V-set_CD47
Ig_DSCAM-DSCAML_C
Kinase-like
Pur_ac_phosph_N
Kdo
DUF5898
AvrM_N
Motif
Other DBs
NCBI-GeneID:
109266499
NCBI-ProteinID:
XP_019304148
Ensembl:
ENSPPRG00000007685
UniProt:
A0A9V1FJW4
LinkDB
All DBs
Position
Unknown
AA seq
2048 aa
AA seq
DB search
MGELPGEEATTMGDVKLAASTQVSKTSISVDHSRVGSMPLTEAPAFIVPPRNLCIREGAT
AKFEGRVRGYPEPQVTWHRNGQPITGGGRFLLDCGIRGTFSLVIHAVREDDKGKYTCEAT
NDSGARQVTVELTVEGTFVKKHSQPVVSKTLGDRFAAPAVETRPSIWGECPPKFATKLGR
AVVKEGQMGRFSCKITGRPQPQVTWLKGDVPLKPSARVSMSEKNGVQVLEIHEVSRDDVG
VYTCMVVNGSGKASMSAELSIQGLDNANRSFVRGTKAAKSDIRKEVTNGATQGLKLGSLE
PAAERKNCSGTQRGGSLTWATGSHPQPLRDASKLEPSGDRPRKALSSPILQKTSSTITLQ
AAKVQPEPRALASGALSPSGEDGERPAAPPPATLPTRHSGLGSQEVVSKVATRKIPMESR
RDYTFPKFESKPQSQEVSEDQIVKFRCEVSGTPKPEVTWFLEGAPVRRREGIVEVYEEGG
CHHLCLLRARARDSGNYSCTASNVQGQVSCGWTLLVKQLAVMEVAPSFSSVLKDCTVIEG
QDFVLQCSVQGIPVPQITWLLNEQPIQYAHSSCEAGVAELHIQDALPEDDGIYTCLAKNN
LGQVSCSARVTVHEKKSDRKSGYLLPAAPSKPVAPLFLQGLSDLKVMDGSQVTMTVQVSG
NPPPEVIWFHNGNEIQESEDFHFEQRGTRHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA
VLMVQEPQDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALSKDTGHF
EVLQNEDVFTLVLKNVQAWHAGQYEILLKNRVGECSCQVSLMLQSSPTRAPLRGREPASC
EGLCGRGASADGGGGDRYGTLRPGWPARGQGWPEEEDSEDVRGVLKRRVETRQHTEEAIR
QQEVEQLDFRDLLGKKVSTKSVSEEHLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSP
QQVDFRSVLAKKGTPKTPVPEKAPLPKPATPDFRSVLGSKKKLPAENGSNNAEALNAKAA
ESPKAVGNAQALGSLKPSGNAKPAETLKPLGNVKPAESPKPVDNAKLAETLKPLSNAKPA
ETPKPVSNTKPVETPKSVSTTKPAETPKSMGNAKPAETPKSVVNAKPAETPKSISATKPA
ETPKSMGNAKPAETLKSMSNAKPAETPKSVGNAKPAETPKSVGNAKPAETGKTAGKEELK
KEVKNDVNCKRGHAGATDNENRSESHGTVPTFKEKLQDVHVMEGQKLLLQCQVFSDPPAT
ITWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGVYKCIAKNGAGQAECSCQVTVD
DAPARENAKAPEMKARRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQK
VRAGESVELFGKVAGTQPITCTWMKFRKQIQESEHIKVENSENGSRLTILAARQEHCGCY
TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSV
EIWDSVDKTWKELATCRSTSFNIQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKP
EEPKDEVEVSDDDEKEPEVDYRTVIVNTEHKVSDFYDIEERLGSGKFGQVFRLVEKKTGK
IWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFE
RIIDEDFELTERECIQYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGL
ARKLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNE
TLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLNCTQCLQHPWLMKDTKNMEA
KKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES
EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS
IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE
GEEEEEEE
NT seq
6147 nt
NT seq
+upstream
nt +downstream
nt
atgggagagctgcccggggaagaggccacgaccatgggggatgtgaagctggctgcctca
acacaggtttccaaaacctccatcagtgtggatcactcgagagtcggttccatgcccctg
accgaggcccctgctttcattgtgccccctcggaacctctgcatcagagaaggagccacc
gccaagtttgaagggagggtccggggttacccagagccccaggtgacgtggcaccgaaat
gggcaacccatcaccggtgggggccgcttcctgctagattgcggtatccgggggactttc
agccttgtgattcatgctgtccgtgaggacgacaagggaaagtatacctgtgaagccacc
aatgatagtggtgcccgccaggtgacagtggagttgactgtagaagggacctttgtgaag
aagcacagtcagcctgttgtttccaaaaccttgggggacagatttgcagcccccgcggtg
gagacccgtcccagcatctggggagagtgcccaccgaagtttgctaccaagctgggccga
gccgtagtcaaagagggacagatgggacggttctcctgcaagatcactggccggccccaa
ccccaggtcacgtggctcaagggagatgttcccctgaagccaagtgcccgtgtatctatg
tctgagaagaatggggtacaagttctggaaatccatgaggtcagccgagatgatgtggga
gtgtacacgtgcatggtggtgaatgggtcggggaaggcctccatgtcggccgagctttct
atccaaggtttggacaatgccaataggtcatttgtgagaggaacaaaggcagccaaatca
gatatcaggaaggaagtgaccaatggagcgacgcaggggctgaaactgggcagcctggag
cctgcagctgaaagaaaaaactgctccggcacccagagaggtggctccctgacctgggct
acaggtagccatcctcagccccttcgggatgcatccaagctggagccgtctggggaccga
cctaggaaagccctgagcagccccatcctgcagaagacttccagcaccatcaccctgcag
gccgcaaaagtccagccggaaccaagagcactggcctcgggcgccctctctccttctgga
gaagacggggagaggccagctgcccctcctccggccaccctccccaccaggcattctggc
ctgggaagccaggaggttgtgagcaaggttgctaccaggaaaatccccatggagagccgg
agggattacacattccccaaatttgaaagcaagccccaaagccaggaagtcagtgaagat
caaatagtcaagttcagatgtgaggtttcagggaccccgaagcctgaagtgacctggttc
ctggaaggtgcccccgtgagaagacgagaaggcatcgttgaggtttatgaagaaggcgga
tgccatcacctctgcctgctcagagcgcgggccagggacagtgggaactacagctgcacg
gcctccaatgtccaaggccaggtgtcctgtggctggactctcttggtgaaacagctggcc
gtgatggaggtggctccctcattctccagtgtcctgaaggactgcactgtcattgagggc
caggactttgtgctgcagtgctcagtgcaggggatcccggtcccccaaatcacttggctg
ctcaatgagcagcccatccagtacgctcactcctcctgtgaggccggcgtggccgagctc
cacatccaggacgccctaccggaggacgatggcatctacacctgtctggccaagaacaac
ttggggcaggtgtcctgcagcgcccgggtcactgtccatgaaaagaagagcgacaggaag
agtggatatcttctgcccgcggctcccagcaagcccgtcgcacccctcttcctgcagggc
ctctctgacctcaaagtcatggatggaagccaggtcaccatgacagtccaggtatcaggg
aatccaccccccgaggtcatctggtttcacaatgggaatgagatccaggagtccgaagac
ttccactttgaacaaagagggactcggcacagcctttgtatacaggaagtgttcccggag
gacacgggcacttacacctgtgaagcctggaacagcgctggagaggtccgcacccaggca
gtgctcatggtgcaagagcctcaggatggcacccagccctggttcatcagcaagccccgc
tcagtgacagcctccctgggccaaagtgtcctcatctcctgtgccatagctggagacccc
ttccctaccgtgcactggctccgagatggcaaggccctctccaaagacactggccacttc
gaggtgctgcagaatgaggatgtgttcacgctggttctaaagaatgtgcaggcctggcat
gccggccagtacgagatcctgctcaagaaccgggttggcgaatgcagttgccaggtgtca
ctgatgctacagagcagccctaccagagcccccctgcgggggagggagcctgccagctgt
gagggcctctgtggccggggagccagtgctgatggtggtggcggtgaccgctatgggacc
ctgaggcctggctggccagcaagagggcagggttggccggaggaggaagacagtgaggac
gtgcggggagtgctgaagagacgcgtggagacccggcagcacaccgaggaggccatccgc
cagcaggaggtggaacagctggacttccgtgacctcctagggaagaaggtgagcaccaag
agcgtgtcagaagagcacctaaaggagatcccagccgagcagatggatttccgcgccaac
ctgcaacggcaagtgaagccaaagactgtgtcagaggaagagaggaaggtgcatagccct
cagcaggtagacttccgctcggttctggccaagaaggggactcctaagaccccggtccct
gagaaggcaccgcttccgaaacccgccaccccagatttccgctcggtgttaggcagcaag
aaaaaattaccagcagagaatggtagcaacaatgccgaggccttgaatgccaaggcagca
gaaagtccaaaggctgtgggcaatgcccaggctttagggtccctgaaaccctcaggcaat
gccaagcctgccgagaccctaaaacctctgggcaacgtcaagcctgccgagtcccccaaa
cccgtggataacgccaagcttgctgagacgctgaaacccttgagtaatgccaagcctgct
gagaccccaaaacctgtgagcaacaccaagcctgtcgagaccccgaaatccgtgagcacc
accaagcctgctgagaccccaaaatccatgggcaacgccaagcctgctgagaccccgaaa
tccgtggttaatgccaagcctgctgagactccgaaatccattagtgccaccaagcctgct
gagaccccgaaatccatgggcaatgccaagccggctgagaccctgaaatccatgagcaac
gccaagccggctgagaccccgaaatccgtgggcaacgccaagcctgctgagaccccgaaa
tccgtgggcaacgccaagcctgctgagacgggaaaaacagctgggaaggaagaactcaag
aaggaggttaagaatgatgtgaactgcaaaagggggcatgcaggagccacagataatgaa
aacagatcagagagccatgggacagtcccaaccttcaaggagaagctacaagatgtccac
gtgatggagggccagaagctgctactccagtgtcaggtgttctctgacccccccgccacc
atcacctggacgctgaatggaaagacactcaagaccaccaagtttatcatcctctcccaa
gaaggctcactgtgctctgtctccatcgagaaggcattgcccgaagacagaggcgtatac
aagtgcatagccaagaatggcgccggccaggctgagtgctcctgccaagtcaccgtggat
gatgctcctgccagggagaatgccaaggccccggagatgaaagcccggaggcccaagagc
tctcttcccccagtgctaggaacagagagtgatgcaactgtgaaaaagaaacctgccccc
aagacacctccgaaggcagccatgcctcctcagatcatccagtttcccgaagaccaaaag
gtgcgcgcgggagagtctgtggagctgtttggtaaagtggcaggcacccagcccatcacc
tgtacttggatgaagttccgaaagcagatccaggagagcgagcacatcaaggtggagaac
agtgagaatggcagcaggctcaccatcctggccgcacgccaggaacactgtggctgctac
actctgctggtggagaacaagctgggcagcagacaggcccaggtcaacctcactgttgtg
gataagccagaccccccggccggcacaccgtgcgcctctgacatccggagctcctcgttg
accctgtcctggtatggctcctcatatgatgggggcagtgccgtgcagtcctacagcgtc
gaaatctgggactcagtggacaaaacgtggaaggaactagccacatgccgcagcacctct
tttaacatccaggacctgctgccagaccgagagtataagttccgtgtgcgtgcagtcaac
gtgtatggaaccagtgagccgagccaagagtctgaactcacagcagtgggagagaaacca
gaggagccaaaggacgaagtggaggtgtcagatgatgatgagaaggaacctgaggtcgac
taccggacggtgattgtcaatactgaacacaaagtgtctgacttctacgacatcgaagag
agactaggctctgggaaatttggacaggtctttcgacttgtagaaaagaaaactggaaaa
atctgggcagggaaattcttcaaggcatattcagcaaaagagaaagagaatatccggcag
gagatcagcattatgaactgcctccaccaccccaagctggtccagtgtgtggatgccttt
gaagaaaaggccaacatcgtcatggtcctggaaattgtgtcggggggtgagctgttcgag
cgcatcattgacgaggactttgagctgacggagcgggaatgcatccagtacatgaggcag
atatcggagggggtggagtatatccacaagcagggcatcgtccacctggacctcaagcct
gagaacatcatgtgtgtcaataagactggcaccagaatcaagctcatcgactttggtctg
gccagaaagctggagaatgcaggatctctgaaggtcctctttggcaccccagagtttgtg
gcacctgaagtgatcaactatgagcccatcggctatgccacggacatgtggagcatcggc
gtcatctgctacatcctggttagtggactttcccccttcatgggtgacaacgataatgaa
accctagccaacgtgacctcagccacctgggatttcgacgatgaagcgttcgatgagatc
tctgatgacgctaaagattttatcagcaatttactgaagaaagatatgaaaaaccgcctg
aactgcacccagtgccttcagcatccgtggctaatgaaagacaccaagaacatggaggcc
aagaaactctcaaaggaccggatgaagaagtacatggcaaggaggaaatggcagaaaacg
ggcaatgctgtgagagccattggaagactgtcctctatggcaatgatctcagggctcagt
ggcaggaaatcctcaacaggatcaccaaccagcccgctcaatgcagaaaaattagaatct
gaagaagatgtgtcccaagctttccttgaggctgttgctgaggaaaagccccatgtaaaa
ccctatttctctaagaccatccgtgatttagaagttgtggagggaagcgctgctagattt
gactgcaagattgaaggatacccagaccctgaagttgtctggttcaaagatgaccagtca
atccgggagtcccgccacttccagatagactacgacgaggatgggaactgctctttaatc
attagtgatgtttgcggggatgatgatgccaagtatacctgcaaggctgtcaacagtctc
ggagaagccacctgcacagcagagctcattgtggaaaccatggaggaaggggaaggggaa
ggagaagaggaagaagaggaagagtga
DBGET
integrated database retrieval system
