KEGG   Panthera pardus (leopard): 109267362
Entry
109267362         CDS       T06062                                 
Symbol
MRE11
Name
(RefSeq) double-strand break repair protein MRE11A isoform X1
  KO
K10865  double-strand break repair protein MRE11
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad03440  Homologous recombination
ppad03450  Non-homologous end-joining
ppad04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    109267362 (MRE11)
   03450 Non-homologous end-joining
    109267362 (MRE11)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    109267362 (MRE11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ppad03032]
    109267362 (MRE11)
   03400 DNA repair and recombination proteins [BR:ppad03400]
    109267362 (MRE11)
DNA replication proteins [BR:ppad03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    109267362 (MRE11)
DNA repair and recombination proteins [BR:ppad03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     109267362 (MRE11)
    BRCA1-C complex
     109267362 (MRE11)
   NHEJ (non-homologous end-joining)
    MRX complex
     109267362 (MRE11)
SSDB
Motif
Pfam: Mre11_DNA_bind Metallophos
Other DBs
NCBI-GeneID: 109267362
NCBI-ProteinID: XP_019305649
Ensembl: ENSPPRG00000010728
UniProt: A0A9V1FMN2
LinkDB
Position
Unknown
AA seq 709 aa
MSPADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLAQENEVDFILLGGD
LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDDNLNISI
PVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSVSVEKIDISPVLLQKGSSKIALYG
LGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDL
VIWGHEHECKIAPTKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRVKGRKMNMQKIP
LHTVRQFFMEDIVLADHPDIFNPDNPKVTQAIQSFCLEKIKEMLENAERERLGNSRQPEK
PLIRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDVIHFFRHREQKENTGEEINLGKLITK
PSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEK
TQRFLKERHIDALEDKIDEEVRRFRESRQKNTNEEDDEVREAMTRARALRSQSEDSASAF
SAEDLMSIDLAEQMADDSDDDITAAANKGRGRGRGRRGRGQSSASRGGSQRGRGGSSLDT
STRSRSSKAAVSTSRNMSIIDAFKSTRPQPSRNVATKNYTEMIEVDETDEEEDMFPTTSK
TEQRCPSTSSSSSKRMSQSQIAKGVDFESDEDDDDDPFMNTSSLRGNRR
NT seq 2130 nt   +upstreamnt  +downstreamnt
atgagtcctgcagatgcccttgacgatgaaaatacatttaaaatcttagttgcaacagat
attcatctgggatttatggagaaagatgcagtcagaggaaatgacacatttgtaacattt
gatgagattttaagacttgcccaggaaaatgaagtggattttattttgttaggtggtgat
ctttttcatgaaaataagccctcaagaaaaacattacatacctgcctcgagttattgaga
aaatattgcatgggtgatcgtcctgtacagtttgaaattctcagtgatcagtcagtcaac
tttggttttagtaagtttccgtgggtgaactaccaagatgacaatctcaacatttcgatt
ccagtgttcagtattcatggcaatcatgatgatcccacaggggcagatgccctgtgtgcc
ctggacatactaagctgtgctggatttgtaaatcactttggacgttcagtgtctgtggag
aagatagacattagtccagttttgctccaaaaaggaagctccaaaattgctttatatggc
ttagggtccattccagatgaaaggctctatcgaatgtttgtcaataaaaaggtaacaatg
ttgagaccaaaagaagatgagaactcttggtttaacttatttgtgattcatcagaacagg
agtaaacacggaaatactaacttcattccagaacaatttttggatgacttcattgatctt
gttatatggggccatgaacatgagtgtaaaatagctccaaccaaaaatgaacaacaactc
ttttatgtatcacaacctggaagttcagtggttacttctctttccccaggagaggctgta
aagaagcatgttggtttgctgcgcgttaagggaaggaagatgaatatgcagaaaattcct
ctccacacggtgcggcagttttttatggaggatattgttctggccgatcatccagacatt
tttaacccagataatcctaaagtaacccaggccatacaaagcttttgtttggagaagatt
aaagaaatgcttgaaaatgctgagcgagaacgtctgggaaactctcgacagccagagaag
cctctcatacgacttcgagtggactatagtggaggttttgaacctttcagtgttcttcgc
tttagccagaaatttgtggatcgggtagctaacccaaaagatgttatccattttttcagg
cacagagaacaaaaggagaacacaggagaagaaatcaacttagggaagttaatcacaaaa
ccttcagaaggcacaactctaagagtagaagaccttgtaaaacagtattttcaaactgcg
gaaaagaatgtgcagctctcacttctaaccgaaaggggaatgggcgaagcagtacaagaa
tttgtggacaaggaagaaaaagatgccatagaggaattagtgaaataccaattggaaaaa
acacagcgatttcttaaagaacgtcatattgatgccttagaagataaaatcgacgaagag
gtacgccgtttcagagaaagcaggcaaaaaaacactaatgaagaagatgatgaagttcga
gaggctatgactagggccagagccctcagatctcagtccgaggactctgcttccgccttt
agtgctgaggaccttatgagtatagatctggcagaacagatggctgatgactctgatgat
gacatcacagcagcagccaacaaaggaagaggccgaggaagaggccgacggggaagaggg
cagagttcagcctcgagaggagggtctcagagaggaagaggaggcagtagtctggatact
tctactcgaagcagaagttcaaaggctgctgtgtcaacatctagaaatatgtctattata
gatgcctttaaatctacaagaccgcagccttcccgaaatgttgctactaagaattataca
gagatgattgaggtggatgagacagatgaagaagaagacatgtttcctaccacttcaaaa
acagagcagaggtgtccgagcacatcatcatcatcaagcaagcgcatgtcccaaagccaa
atagctaaaggggtcgattttgaatcagatgaggatgacgacgatgatccttttatgaac
actagctctttaagaggaaacagaagataa

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