Panthera pardus (leopard): 109267831 Help Entry 109267831         CDS       T06062                                  Symbol APOB Name (RefSeq) apolipoprotein B-100 isoform X1   KO K14462   apolipoprotein B Organism ppad  Panthera pardus (leopard) Pathway ppad04975   Fat digestion and absorption ppad04977   Vitamin digestion and absorption ppad04979   Cholesterol metabolism ppad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppad00001]  09150 Organismal Systems   09154 Digestive system    04975 Fat digestion and absorption     109267831 (APOB)    04979 Cholesterol metabolism     109267831 (APOB)    04977 Vitamin digestion and absorption     109267831 (APOB)  09160 Human Diseases   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109267831 (APOB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ppad04147]     109267831 (APOB)    00536 Glycosaminoglycan binding proteins [BR:ppad00536]     109267831 (APOB) Exosome [BR:ppad04147]  Exosomal proteins   Exosomal proteins of other cancer cells    109267831 (APOB) Glycosaminoglycan binding proteins [BR:ppad00536]  Heparan sulfate / Heparin   Others    109267831 (APOB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Vitellogenin_N Vit_open_b-sht DUF1081 ApoB100_C MltA PH_RBD PARP_reg Motif Other DBs NCBI-GeneID:  109267831 NCBI-ProteinID:  XP_019306363 Ensembl:  ENSPPRG00000021875 LinkDB All DBs Position Unknown AA seq 4440 aa AA seqDB search MGPPRPTLLLLLLLAAAGAWAQDEVLENVSPGCPKGATRFKHLRKYVYNYEAESSSGVPG AADARSTTRINCKVELEVPQLCSFILKTSQCALKEGYGFNARGKPLLHKTSNSEEFAAAM SKYELRLAIPEGKQVLLYPEKEEPKHILNIKRGIISALLVPPETEEDEQVLFLDTVYGNC SSDLTVKTKKANVATGISIERNLEKCDRFKPISTGVSPLALIKGMIGPLSTLISSNQSCQ YTLDPKKKHVSEAICKEQHVFLPFSYKNKYGMMAQVTQTLKLEETPKINSRFFDEGTEEV GLAFEITKSTSPPKQAEAIVKTLQELQTLHVSDQNAQRANLFNKLVTELRGLNNEAITSL LPKLIQVSSPVTLQALIQCGQPQCYTHILQWLRSEKANPLLTDVVTYLVALMPEPSAERL QEIFSTAKEQQSRTTLYALGHVVNNYHETNPVVTQALLDIADYLLEQIRDDCTGNEDHTY LILRVIGNTGRTMETVSPRLTSSILKCIQSSEPSLLIQKAAIQALRKMELKDEVREVLLR VFLSDASPGDKRLAAYLMLMRGPSQSDINQIVQFLPWEQNEQVKNFVASHITNILNSEEL YIKDLKSLVEDALKGSQLPTIMDFTKFSRNYHLSKSVSLPSLDPVSAKIEGNLIFDPNNY LPKESMLKTTLTVFGFAPADLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVDGQV PDHVSRVLVDHFGYTKDDKREQDMVNGIMLNIEKLIKDLKSREFPEARAYLRILGEELGF VRLHDLQFLGKLLLNGVRTLQGIPQMIGEAIKKGLRSDLFLHYIFMDNAFELPTGLGLQL QISSSGVITPGIRGGMKLEVANMQAELMAKPSVSMEFVTNMGIIIPDFSRTGIQMNTNFF HETGLGVQVAMKAGQLKFTVPSPTRPIRLFSGSNTLHLVSTTKTQEVPPLTENRQSWSTC KPLFTGLDYCTSGSYSNASSPEATSYCLLTGGTRFALELKPTGEVEQYSASATYELQREG GILVDTLKFVTQTEGVKQSEATMMFKYNRQSMTLSSEIQIPDFDVDLGTVLRVRDESAME KKSYKLTLDIQNKKITEVTLTGHVSYDRSEEGKIKGVISIPRLQAEARSEILTQWSPTKL LFQMDSSATAYGSTISKKLAWRYDEEKIEFEWNTGTNVDTKKAASNFPLDLSDYPKSLHM YANSLLDHRVPQTDMTFRHMGSKLIVATNTWLQKASGSLPYAQNLQDHLSGLKELYLQKM GLPNFHIPENLFLKSDGRVKYTLNKNSVKIEIPLPFGGKSSKDLKMLEAIRTLAINFKSV EFYLPSQEFQVPTFTIPKSYQLRVPLLGVLDLSTSIYSNLYNWSASYTGGNTSTNHLRLQ TQYYMKADSVVDLLSYSVQGSGETTYDHKNTFTLSYDGSLHHKFLDSKMVFSHTEKIRNN PVSKSLLTFYASSAWGPQMSASVHVDSKRKHHLYVKEVKIDGQLRVSSFHAKGTYDLSYQ KDSTTGQLSGESNLRFNSSYLQGTNQITGRYEDGIVSLTSTSNLQGGIIKNTASLKYENY ELTMKSDTDGKYEDFATSNKIDLTFSEQNALLRSEYQADYKSLRFFTLLSGTLNSHGLEL NADILGTDKSNSGVHKATLRITRDGMSTSATSNLRYSPLVLENELNAALGPSGASVRLTT NGRFREHNAKFSLDGKAALTEVSLGSVYQAMILGLDSKNIFNFKISQEGLKLSNDMMGSY AEMKLDHTNNLNIAGLSLDFSSKLDNIYSSDKFYKQNFNLQLQPYSLVTTLNNDLKFSAL DLTNSGKLRLEPLKLNVGGNIKGVYQNNEIKHIYTISYADLSTSYKTDTVAKVQGTEFSH RLNTNIAGLASAIDISTNYNSDSLHFSNVFHSAMAPFTMTIDAHTNGNGKLSFWGEHTGQ LYSKFLLKAEPLALTVSHDYKGSTNHHLPLKSSISASLDHKVSALLTPAEQTATWKLKTQ LNENEYSQDFDAYNTKDKVGVELRGQALADFAMLDFSIQVPFFLSEPTNVIDALGMRDAI DQPQEFTVVAFVKYDKNQDVHTINLPFFKILPEYFEKKRMVIIMALETIQRELKIINIDQ FMTKYREALDKLPQQVNDYLNAFNWESQVASAKEKLSAFTKNYRMTENDLQIALNNTKIN LNEKLSQLQTYVIQFDQYIKDNYDLHDFKTAIAEIIDQIIEKLKTLDEHYHIHENLVKTI HDVYLFIEKIDFNRIGSSPASWIQNADTRYQIRIQMQEKLQQLKTQIQNVDMRHLAEQLK QQVEAMDVRVLLHKLRTTIPFPRVKEIIEHIKYYVIHLMEDFVVVDKINAFGAKVHKLIK MYKIDQHMQVLMDTSVQLAHKYQLKETVEKLSNVLQQVNIKDHFEKLVRLIDDAIKQLKA LSFKKIIEEVNRFLDMLIKKLRSFDYHQFVDEANNKIREVTQRINGEIQALALSEKAIAL TLFVEDIKAMVSVHLENTKDIQITLFFDWLQEALSAVFLTSMKAKFQETLEDIRDRVYQM DIQQEVQRYLSLVGQVYSTLVTYISDWWSLAAKNLTDFAEQYSLQDWAGNLKALVEQGFT IPEIQTIFGTIPAFEVSLRALQEATYQTPDIIVPLTDLKIPSVQINFKSLKDIKIPSRFA TPEFTVLNTFHVPSFTIDLVEIKVKIIRTIDQMLSSELQWPVPEIYLRDLKGLDTILAGI TVPDFYFPEIAIPEFIIPNLDLKNYQIPDLHIPEFQLPHLSHTVEVPSFGKLHGILKIQS PLFVLDANANIQNATTSGNKAEIAASITAKGESKLEVLNFDFQANGQLSDSNINPLVMKQ SMRFSSKYIKTEHESEVLFFGNAVEGKSNTVAGLHTEKNMLEFSNGVLVRINNQLTLDSN TKYFHKLNIPKLDFSSQAELRNEIKTLLEAGHVAWTSSGIGSWKWAHQTFSDEGAHESQV SFTVEGPITSFGLSNKISSKHLRLSQNLVYESGFLDFSKFEIQSQVESQYVGRSVLAAKG TALLGERKAEITGNHDAHLNGKVIGTLKNSLFFTAQPFEITASTNNEGNLKVSFPLKLIG KVDFLNNYALFLSPSAQQASWQASARFNQYKYHQNFSAGNNENSIEAHVGINGEANLDFL NIPLTIPEMTLPYTVLTTPQVKDFSLWEKTGLKEFLKTTKQSFDLSVNAQYKKNKDKHSI PIPFYVKGFQAVSTPNNILIPAMGNITYDFSFKSSVITLNANAGLYNQSDIVAHFVTSSS SVTDTLEYKLEGTSSLTRKRGLKLATALSLSNKFMEGNHDSTISLTKKSMEASVTTSAKV QIPILKMNFKQELNGNTKSKPTISSSIGLTYDFNSPKLYSTATGAVDHKLILESLTSYFS VESSTKGDIKGSVLSREYSGTIASEASTYLNSKSTRSLVKLQGASKVDGIWNLEVKENFA GEATIRRIYAIWEHNTKNHLQLEGFFLTSGEHTSKATLELSPWKMSALVQVRASQPNSLL DINYLGQDVSLNANSEHQKVSWKSEVQVHSGFFQNNVHLSNDQEEARLDIASSLKVSLWF LKDIALPVYDKSLWDLLKLDVTTSIDRKQYLHASTSLVYTKNPNGYHFSVPVQELADKFI VPRLKLNGLSSGLVIPTFQVPFTDLQVPSYTLDFSEIKIYKKLSTLPFALSIPTLPKVKF PKVDVLTKYSEPEDASVPFFEITIPASQLTVSQFTLPKSISVGSAVEYLNEVASKIADFE LPAITMPEQTIEIPSIKFSVPAGIFIPSFGALTAHFGVASPLYNATWSTGLKNKVEYVET FLNSTCSSTIQFLEYDLNVVGTHKIEDGVLFYRPKGTFAHHDISVEYKEDNKYQGLWDWK EDIRLDITSPTFTDVHLHYQLNKNSLSSSVSSPAIGTVALDLEGNNNTLKWNLYYRPQSS LDKKLNIFKTEWRYQESDDKSQIKVSWEEEAVSELLSSLKDNVPKATGVLYDYANKYHQE YTGLNLRDASLKLRRSLQNSAEWAYQSTMRQTDEVDMGLQRVARATTRTYQQWKEKAQDL YRELLAQEGQADFQGLQNKVFERLMGVTQEYKDIVSHQVDSLIDFLKFTRFQLPGKAGTY SRDELFTMVMREVGQVLSQVYSKIHSGLEILFSYFQDLMEKSELIKDVEIKFPFNSESYK LRDVVLEFGNLLKSLSQKIQDALNNLQSIKTTEMLSHLQRYLERAFQEIEEEIQHLKGKK FTYLINDIQHVINRIFKKYIPTAFTFLKINFDKFNELVQNQLQEASQQLQQLHQLIKDLH KEYVDPTVVSWTSRYYELEEKIISLIKNLVDVLMDFHSKYTISTAGLISELSNQVEQFVQ KDIQEYLSILTDADGKGKEKIAELSTSAQEIIKSQATAMKEIISDYHQQFRYKLQDFSDQ LSDYYEKFITESKRLIDLSTQTYHMFLRYITELLKELQSATVNNMIPSTKVSPGEFTITF NT seq 13323 nt NT seq  +upstreamnt  +downstreamnt atgggcccgccgaggcccacgctgctgctgctgctgctgctggcggccgccggcgcctgg gcgcaagacgaggtgctggaaaacgtcagccccggctgcccaaaaggagcaactcgattc aagcacctccggaagtatgtgtacaactatgaggctgagagttccagtggtgttcctggg gccgctgatgcaagaagtaccaccaggatcaactgtaaggttgaactggaggtgccccaa ctgtgtagcttcatcctcaagacgagccagtgtgcgctgaaggaggggtatggcttcaac gctagggggaagccgttgctgcacaagaccagcaactctgaggagtttgctgctgccatg tccaagtacgaactcaggctggccattcctgaaggaaagcaagttttactttacccagag aaggaggagcctaaacacatcctgaacatcaaaaggggcatcatttctgccctcctggtt cctccagagacagaagaggatgagcaagtgttgtttctggatactgtgtatggaaactgt tccagtgacttaactgttaaaacaaagaaggcaaatgtggcaacaggaatctccatcgaa agaaacctggagaagtgtgatcgcttcaagcccattagcacaggagttagcccacttgct ctcatcaaaggcatgatcggccccttgtcaactctgattagtagcaaccagtcctgccag tacactctggaccccaagaagaagcatgtgtcagaagccatctgtaaggagcaacacgtg ttcctgcctttttcctacaagaataagtatgggatgatggcacaggttacacagacattg aaacttgaagaaacacctaagatcaacagccgcttctttgatgaaggtaccgaggaggtg ggtctggcctttgagatcaccaaatccacatcacccccaaagcaggccgaggccattgtg aagactctgcaggaactgcaaacattacacgtctctgaccagaatgcccagagagctaac ctcttcaataaactggttactgagctgagaggcctcaacaatgaggcaatcacatccctc ttgccaaagctgatccaggtgtccagccccgtcaccttacaagctttgattcagtgtgga cagccccagtgttacactcacatcctccagtggctgagaagtgagaaggccaaccccctt ctgacagatgttgtgacctacctggtggccctgatgccagagccctcggccgagaggctg caggagatcttcagcacagcaaaggagcagcagagccgaaccactttatatgctctgggt cacgtggtcaacaactatcatgagacaaaccctgtggtgacccaggccctgctggacatt gctgattacctgttggaacagattcgcgatgattgcactgggaacgaagatcacacctac ttgattctgagggtcattggaaatactggcagaaccatggagacagtatccccaagactc acgtcttcgatcctgaaatgtatccaaagttcagagccatcactgctgattcagaaggct gccatccaggccctgcggaaaatggaacttaaagatgaggtccgggaagtccttcttcgg gttttcctcagtgatgcctctccaggggataagcgactggctgcctatctcatgctgatg aggggcccttcccagtcagatattaatcagattgtccagtttctcccatgggaacagaat gaacaagtgaaaaactttgtggcttcccacatcaccaacatcttaaactcagaagaactg tatatcaaagacttgaaaagcttagtggaagatgctttgaaaggatctcaactcccaacc atcatggacttcacaaaattttcccggaactaccacctctccaaatctgtttcccttcca tcacttgacccagtctcagccaaaattgaaggaaatcttatatttgatccaaataattac cttcctaaagaaagcatgctgaaaacaaccctcactgtctttggatttgctccagcggac ctctttgagattggtttggaaggaaaaggctttgagccaacattggaagctctttttgga aagcaaggatttttcccagacagtgtcaacaaggctttgtactgggttgatggccaagtt cctgatcatgtctccagggtcttggtggaccattttggctataccaaagatgataaacgt gagcaggacatggtcaatggaattatgctcaatattgagaagctgatcaaagatttgaaa tccagagaattcccagaagccagagcctacctccgcatcctgggagaggagcttggcttt gtcaggcttcatgacctccagttcctgggaaagctgctgctgaatggtgttcgcactctg caggggatcccccagatgattggcgaggccatcaagaaaggtttaaggagcgacttgttt cttcactacatcttcatggacaacgcctttgaactccccaccggacttgggttacaattg caaatctcctcctctggagtcatcactcctggaatcaggggtggaatgaagctggaagta gccaatatgcaggcagagctgatggcaaagccctctgtgtccatggagtttgtgacaaat atgggcatcatcatcccggacttttcaaggacggggatccaaatgaacaccaacttcttc cacgagacaggcctgggtgtgcaagttgccatgaaagccgggcagctgaagttcacggtt ccgtctcctacgaggccaatcaggctgttcagtggcagtaacacgttgcatttggtctct accaccaaaacacaagaggttccacctctcactgagaacaggcagtcctggtcgacttgc aagcctctctttactggcctggactactgcacgtcgggctcttactccaacgccagttcc ccagaagccacctcctactgtctgctgaccgggggcaccaggtttgctctggaactgaag cccactggagaagtagaacagtattctgccagcgcaacctacgaactgcagagagagggt ggaatcttggtggacaccctgaagtttgtaactcagaccgaaggtgtgaagcagtctgag gctactatgatgttcaaatataaccggcagagtatgactttgtctagtgaaatccaaatt ccagattttgatgttgaccttgggacagtcctcagagttcgtgatgaatctgctatggaa aaaaagtcttacaagctcactttggacatccagaacaagaaaatcactgaggtcactctt accggccacgtaagctacgacagaagtgaagaaggcaaaatcaaaggtgttatttccata ccccgtctgcaagcagaagccagaagtgaaatcctcacccagtggtctcccacaaaacta ctcttccaaatggactcgtctgctacagcttatggctcaacaatttccaagaagctggca tggcgttatgatgaagagaagattgaatttgaatggaacacaggcaccaatgtggatacc aaaaaagcagcttctaacttccccctggatctctctgattatcctaaaagcttgcatatg tatgccaatagtctcttggatcacagagttcctcaaacagacatgactttccggcacatg ggttccaaattaatagttgcaacaaatacatggcttcagaaggcatctgggagtcttcct tatgcccagaacttgcaagatcacctcagtggcctaaaagaattgtacctccagaaaatg ggattgccaaacttccacatcccagaaaacctcttcttgaaaagtgatggccgggtcaaa tacacattgaacaagaatagtgtgaaaatcgagattcctttgccttttggtggcaaatcc tccaaagatctaaagatgttagaggctattcggacactagccatcaacttcaagtcggtg gaattctacctgccatctcaggaattccaagtccccacttttaccattcccaagtcgtat caactgcgagtacctctcttgggtgttctagacctctctacgagtatctacagcaatttg tacaactggtctgcctcgtacactggtggcaacaccagcaccaaccatttgaggcttcag actcagtactacatgaaggctgactctgtggttgacttgctttcctacagtgtgcaagga tctggagaaacaacatatgaccacaagaatacattcacattgtcatatgatgggtctcta caccacaaatttctggattcaaagatggtattcagccacacagaaaaaattagaaacaat ccagtctcaaaaagcttgctaacattttatgcttctagtgcctggggtcctcagatgtct gcttcagtacatgtggactcaaaaaggaaacatcatttgtatgtcaaggaagtcaagatt gatgggcagctcagagtctcttcattccatgccaaaggcacatatgatctatcttatcag aaggattctaccactggccagttaagtggagagtccaacctgaggtttaactcctcctac ctccagggcaccaaccagataacaggaagatatgaggatggaattgtctccttaacctcc acctcgaatctgcaaggtggcatcattaaaaatactgcttccctaaaatatgagaactat gagctaactatgaaatctgacacagatgggaagtacgaggactttgccacttctaacaaa atagatctcaccttctctgagcaaaatgcattgctacgttctgagtatcaggctgattac aagtcattgagattcttcaccctactttctggaacactcaattcccatggccttgaatta aatgctgatattttgggcactgacaaaagtaatagtggtgttcacaaagcaacactaagg attacccgagatggaatgtctaccagtgcaacgagtaacttgaggtatagtccactggtg ctggagaatgagctgaatgcggcacttggcccctctggagcatctgtgagactaacaacg aatggccgcttcagggaacacaatgcaaaattcagcctagatggaaaagctgccctcaca gaggtgtccttgggaagtgtttatcaggccatgattttgggtcttgacagcaaaaatatc tttaacttcaaaatcagccaagagggacttaagctttcaaatgacatgatgggctcttat gctgaaatgaagcttgaccacacgaacaacctgaacatcgcagggttgtcactggacttc tcttcaaaacttgacaacatttatagctctgacaagttttataagcaaaattttaactta cagctacagccctattctcttgtaactactttaaacaatgacctgaaattcagcgctctg gatctaaccaacagtgggaaattacgactagagcccctgaagctgaatgtgggtgggaac ataaaaggagtctaccaaaataatgaaataaaacacatctacaccatttcttatgctgac ttatccacaagttataagacagacaccgtagctaaggtgcagggtacagagttcagccat cggctcaacacaaacatcgctgggctggcttcagccattgacatcagtacaaactacaat tctgattcactccatttcagcaacgtttttcactctgcaatggcgccatttacaatgacc atcgacgcacatacaaatggcaatggaaaactgagtttctggggagagcatactggtcag ctgtatagcaaattcctgttgaaagcagaacctctggcccttactgtctctcatgattac aaaggatccacaaatcaccatcttccattgaagagcagcatcagtgcttctcttgatcac aaagtcagtgccctgctcactccggctgagcagacagccacctggaaactcaagacccag ctgaacgaaaatgaatacagccaggactttgatgcttacaatacaaaagacaaagttggt gtggagcttagaggacaagccctggctgactttgccatgctagacttctcaattcaagtg ccgtttttcctcagtgaacccaccaacgtaatcgatgctttagggatgagggatgctatt gaccagcctcaggaattcactgttgttgcttttgtaaaatatgataagaatcaagatgtt cacaccatcaacctcccattctttaaaatcttgccagaatattttgagaagaaacgaatg gtcattataatggcactggaaaccatacagagagaattgaaaatcatcaatattgatcaa tttatgacgaaatacagagaagccttggacaaactcccacagcaagttaatgattatctg aatgcattcaattgggagagtcaagttgcgagtgccaaggaaaaactaagtgctttcaca aaaaattacagaatgacagaaaatgatctacaaattgcattgaacaataccaaaatcaac ctcaatgaaaaactatctcaactacaaacatatgtgatacaatttgatcagtatattaaa gataattatgatttacatgattttaaaacagctattgctgagattattgatcaaatcatt gaaaaattaaaaactcttgatgaacattaccatatccatgaaaatttagtaaaaacaatc catgatgtgtatttgtttattgaaaagattgattttaacagaattggaagtagtcctgca tcttggattcaaaatgcagatactaggtatcaaatcagaatccagatgcaagaaaaattg caacagctcaagacacagattcagaatgtagacatgcggcaccttgctgaacagttaaaa caacaggttgaggctatggatgttagagttcttttacataagttgagaactacaattcca tttccaagagtaaaagaaattattgagcacatcaaatactatgttatccatctcatggaa gactttgtagtagttgacaaaatcaatgcttttggagccaaggtccataagttaattaag atgtataaaatagaccaacacatgcaggttttaatggatacatcagtacagttggcccat aaatatcagttgaaggagactgttgagaagctaagtaatgtcttacaacaagttaacata aaagatcactttgagaaattggttaggcttattgatgatgctatcaagcaacttaaagca ctgtcttttaaaaaaatcattgaagaagtaaacagattccttgacatgttgataaagaaa ttaaggtcatttgattatcaccagtttgtagatgaagccaataacaaaatccgcgaagtg actcagagaatcaatggtgaaatccaggccctggcactttcagagaaagctatagcacta acactgtttgtggaggacatcaaggccatggtctcagtccatctggaaaacacaaaggac atccaaataaccttattctttgattggttacaggaggctttaagtgcagtatttttaact tccatgaaagccaaattccaagagactctggaagatatacgagacagagtgtatcaaatg gacattcagcaggaagttcagcgatatctgtccctggttggccaggtttacagcacactt gtcacttatatttctgattggtggagtctcgctgctaagaaccttactgactttgcagaa cagtattctctccaagactgggctggaaacctgaaagcattggtagaacaagggttcact attcctgaaatccagaccatctttgggaccatccctgcctttgaagtcagtctccgtgct cttcaggaagctacatatcagactcctgacatcatagtccccctgacagatttgaagatt ccatcagttcagatcaacttcaaaagtttgaaagatataaaaatcccatccaggtttgcc acaccagagtttactgtccttaacacattccatgttccttcttttacaattgacttggta gaaataaaagttaagatcatcagaaccattgaccaaatgctgtccagtgagctgcagtgg ccagttccggaaatatacctgagggatctgaaggggttggacaccattcttgctggaatc actgtgccagacttctattttccagaaattgcaattccagaattcataatcccaaatctt gatttaaaaaattaccaaattcctgaccttcacataccagaatttcagcttccccacctg tcacacacagttgaagtcccttcttttggtaagctgcatggcattttgaaaatccaatct ccccttttcgtattagatgcaaatgccaacattcagaatgcaactacttcagggaacaag gcggagatcgcagcttccatcactgccaaaggagagtccaaattagaagttctcaatttt gattttcaagccaatggacagctttcagactctaatattaatccactggttatgaagcaa tccatgaggttctccagcaagtacataaaaacagagcatgagagtgaagtgctgtttttt ggaaatgctgttgagggaaaatcaaatacagtggcgggtttacacacagaaaaaaatatg ctggaatttagtaatggtgtgcttgtcaggataaacaatcagcttactttggacagcaac acaaagtacttccacaaattgaacatccccaaattggacttctccagccaggctgagctg cgtaatgaaatcaaaaccctgttggaagctggacacgtagcatggacttcttctggaata gggtcatggaaatgggcccaccagacattctcagatgaaggagcacatgaatcacaagtt agctttactgtggaaggacccatcacatcctttggattgtctaataagatcagtagcaag catctaagactaagccaaaacttggtttatgaatctggcttccttgacttttctaaattt gaaatccagtcacaggttgaatcccagtatgtgggccgcagtgttctagctgctaaaggc acagcattgcttggagaaaggaaggcagagataactggtaaccatgacgctcatttaaat ggaaaagttattggaactttgaaaaattctcttttctttacagcacagccatttgagatt actgcatccacaaacaatgaagggaatttgaaagttagttttccattaaaattgataggg aaggtagacttcctgaataattatgcactgtttttgagtcctagtgcccagcaagcaagc tggcaagcaagtgccaggttcaatcagtataagtaccatcaaaacttctctgctggaaac aatgagaacagcattgaggcccacgtaggaataaatggagaagccaatctggattttctg aacattcctctaacaattcctgaaatgactctaccttacacagtgctcacaactcctcag gtgaaagatttctccttatgggaaaaaacaggcttgaaggaattcttgaagacaacaaag caatcgtttgatttaagtgtaaatgctcagtataagaaaaacaaagacaagcattccatc ccaatccctttttatgtaaaaggtttccaggcagtgagtaccccaaacaatattttaatt ccagccatgggcaatattacctatgacttttcctttaagtcaagtgtcatcacactgaat gccaatgctggactttataaccagtcagatattgttgctcattttgttacttcctcttct tccgtcactgacacactggagtacaaattagagggcacctcaagtttgacaaggaaaaga ggcttaaagctagccacagctttgtctctgagtaataaattcatggaaggcaatcatgac agtactattagtctgaccaagaaaagcatggaagcatcagtgacaacatctgcaaaagtc caaattcccattttgaaaatgaatttcaaacaagaacttaatggaaataccaagtcaaag cctactatctcttcatccattgggttaacatatgatttcaattctcccaaactttactct actgctactggggcagttgaccacaagctcattttagaaagccttacctcttacttttct gttgagtcatctaccaaaggagatatcaagggttcagtcctttcacgggaatattcagga actattgccagtgaggccagcacttatttgaattccaagagtactaggtctttagtgaag ctgcaaggggcttccaaagtcgatggtatctggaaccttgaagtaaaagaaaattttgct ggagaagccactatccgacgcatctatgccatctgggaacacaatacgaaaaaccattta cagctagagggcttctttttaacatctggagagcatacaagcaaagccaccctggaactc tccccatggaaaatgtcagcccttgttcaggtccgtgcaagtcagcccaattccctcctt gatatcaattaccttggccaggatgtgtccctgaatgctaactctgagcatcagaaggtc agctggaaaagtgaggtccaggttcattctgggtttttccagaacaatgtacacctttcc aatgaccaagaagaagcacgccttgacattgcaagttccttaaaagtgtctctgtggttc ctcaaagacattgccctaccagtttatgacaagagcttatgggacctcctaaagctagat gtaaccaccagcattgatagaaaacagtatcttcatgcttcgacttctctcgtgtacacg aaaaaccccaatggctatcatttctctgtccctgtgcaagaattggctgataaattcatt gttcccagactgaaattaaatggcctaagttcaggtcttgtcatacctacattccaagtc ccatttactgatcttcaggttccatcctacacacttgatttcagtgaaataaaaatctac aagaagctaagcactttgccatttgccctcagtataccaacactacccaaagtgaaattc cccaaagttgatgtgttaacaaaatattctgaaccagaagatgcctcagttccctttttt gaaataactatacctgcatctcagttaactgtgtcccaattcacccttccaaaaagtatt tcagttggcagtgctgttgagtatctaaatgaggtggccagcaagattgcagactttgag ttgccagctattaccatgcctgagcagactattgagattccttccatcaagttctctgta cctgctggaattttcataccctcctttggagcactgactgcacattttggagtggcctct cccctgtataatgctacttggagcactggtttgaaaaacaaagtagaatacgttgaaaca ttcctgaattccacgtgcagttcaaccattcagttcctggaatatgatctaaatgttgtg ggaacacacaaaattgaagatggcgtgttattctataggccaaagggaacattcgcacac catgacatcagtgtggaatataaagaagataacaaatatcaaggactttgggactggaaa gaagacattcgcctcgacatcaccagcccaacattcactgatgtccatctgcactaccaa ctaaataagaatagcctctcctcctcagtgtcctccccagccataggcactgtggccttg gacttggaaggcaataacaataccttaaaatggaacttgtactaccgccctcagtcctct ctggataaaaaactcaacatattcaaaactgagtggaggtaccaggaatctgatgataaa agtcagatcaaagtcagctgggaagaagaggcagtgtctgaactactaagctctctcaaa gacaatgtgcccaaggccaccggggtcctttatgactatgccaacaagtatcaccaggag tacacaggactcaatctgagagatgcttctttaaaattgagaagaagtctgcagaacagt gctgagtgggcctatcaaagcaccatgaggcagactgatgaggtggatatggggctccag agggtagccagggccaccactagaacctaccagcagtggaaggaaaaggcccaggatctg taccgtgaactgttggctcaggagggccaagctgatttccagggactccagaataaggtg tttgagagattaatgggagttactcaggaatacaaagacatagtcagtcatcaggttgac tcattgattgacttcctaaagttcaccagattccagctcccaggaaaagccgggacatat tctagagatgaactcttcactatggtcatgagggaagtagggcaggtgctgtcacaggta tattcaaaaatccatagtgggttagaaatactgttttcctatttccaagacctgatggag aaatctgagctaatcaaggatgtagagattaaatttccttttaattcagagagctataaa ctaagagatgttgtcttggagtttgggaacctgttgaaatctttatcacaaaagatccag gatgcacttaataaccttcagtctatcaagactacagagatgctaagtcatcttcagaga tatttagaaagagctttccaagagatagaagaagaaattcaacacttaaagggaaagaaa tttacttatctcattaatgatattcaacacgtgatcaatagaatcttcaaaaaatatatt ccaactgcttttacattcctgaaaattaactttgacaagtttaatgaacttgtccaaaac caactccaggaagcttctcaacagttacaacagctccatcagctcataaaggatcttcac aaagaatacgttgatccaactgtggtcagctggacatcaaggtattatgaacttgaagaa aagatcatcagcttgatcaagaacctagtggatgtccttatggacttccattccaaatac actatcagtactgctggtttgatttccgaactctcaaatcaagttgagcagtttgtgcag aaagatatccaggaataccttagcatccttactgatgcagatggaaaagggaaagagaag attgcagagctttctaccagtgctcaggaaataattaaaagccaggccactgcaatgaag gaaatcatttctgattaccaccagcagttcagatataaactacaggatttttcagaccaa ctctctgattactatgaaaaattcattactgagtccaaaagattgattgacctgtccact caaacataccacatgtttctgagatatatcactgaattactgaaagagctacaatcggcc acagtcaataacatgatcccctccacaaaggtttctccaggagaatttactatcaccttt taa

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