Panthera pardus (leopard): 109267871 Help Entry 109267871         CDS       T06062                                  Symbol GCK Name (RefSeq) glucokinase   KO K12407   glucokinase [EC:2.7.1.2] Organism ppad  Panthera pardus (leopard) Pathway ppad00010   Glycolysis / Gluconeogenesis ppad00052   Galactose metabolism ppad00500   Starch and sucrose metabolism ppad00520   Amino sugar and nucleotide sugar metabolism ppad00524   Neomycin, kanamycin and gentamicin biosynthesis ppad01100   Metabolic pathways ppad01200   Carbon metabolism ppad01250   Biosynthesis of nucleotide sugars ppad04910   Insulin signaling pathway ppad04911   Insulin secretion ppad04917   Prolactin signaling pathway ppad04922   Glucagon signaling pathway ppad04930   Type II diabetes mellitus ppad04950   Maturity onset diabetes of the young ppad05230   Central carbon metabolism in cancer Module ppad_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ppad_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     109267871 (GCK)    00052 Galactose metabolism     109267871 (GCK)    00500 Starch and sucrose metabolism     109267871 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     109267871 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     109267871 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     109267871 (GCK)    04910 Insulin signaling pathway     109267871 (GCK)    04922 Glucagon signaling pathway     109267871 (GCK)    04917 Prolactin signaling pathway     109267871 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     109267871 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     109267871 (GCK)    04950 Maturity onset diabetes of the young     109267871 (GCK) Enzymes [BR:ppad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      109267871 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  109267871 NCBI-ProteinID:  XP_019306406 Ensembl:  ENSPPRG00000001844 LinkDB All DBs Position Unknown AA seq 517 aa AA seqDB search MGSAEQTSGGAVPLEGGIWAKRQLCLSLALSLPILTPMVQTRQEGSLEYLLLCQQAETTL LSPPPPQAEQILADFQLQEADLKKVMWRMQKEMARGLRLETHEEASVKMLPTYVRSTPEG SEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISE CISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDA IKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMHNVELVEGDE GRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGELVRLVLLK LVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPSATDCDIVR RACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHAIVR RLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1554 nt NT seq  +upstreamnt  +downstreamnt atgggttcagcagagcagacgtcaggtggtgctgtgcccctggaaggaggcatctgggcc aagaggcagctgtgcctgtcactggccctgtcactgcctatcctgacacccatggtgcag actcgccaggaggggtctctagagtacttgctcctgtgccagcaggctgagaccactctg ctctcacccccacccccgcaggcagagcagatcctggccgacttccagctgcaggaggcc gacttgaagaaggtgatgtggcggatgcagaaggagatggcgcgaggcctgcggctggag acccacgaggaggccagtgtgaagatgctgcccacctacgtgcgctccaccccggaaggc tccgaagttggggacttcctctccctggacctgggcggcaccaacttcagggtgatgctg gtgaaggtgggggagggcgaagaggggcagtggagcgtgaagaccaagcaccagatgtat tccatccccgaggacgccatgacgggtactgctgagatgctctttgactacatctctgag tgcatctccgacttcctggacaagcaccagatgaagcacaagaagctgcccttgggcttc accttctccttccctgtgaggcatgaggacatcgacaagggcatcctcctcaattggacc aagggcttcaaggcctcaggagcagaagggaacaacatcgttgggctcctacgcgatgcc atcaaacggagaggggactttgaaatggacgtggtggcgatggtgaatgacactgtggcc acgatgatctcctgctactatgaagaccgccggtgtgaggttggcatgattgtgggaaca ggctgcaatgcctgctacatggaggagatgcacaacgtggagctggtggaaggggacgag ggccgcatgtgcgtcaacaccgagtggggcgccttcggggactccggagagctggacgag ttcctgctggagtatgaccgcgtggtggacgagaactccctgaaccctgggcagcagcta tacgagaagctcatcggcggcaagtacatgggcgagctggtgcggctcgtgctgctgaag ctcgtggacgagaacctgctcttccgcggggaggcctcggagcagctgcgcacgcgcggc gccttcgagacgcgcttcgtgtcgcaggtggagagcgactcgggcgaccgcaagcagatc tacaacatcttgagcactctggggctgaggccctcagccaccgactgcgacatcgtgcgc cgcgcctgcgagagcgtgtccacacgcgccgcgcacatgtgcgccgcggggctggcgggc gtcatcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatcaccgtgggcgtg gacggctctgtgtacaaactgcaccccagcttcaaggagaggttccacgccatcgtgcgc aggctgacgcccagctgcgagatcaccttcatcgagtcggaggaaggcagcggccgaggc gccgccctggtgtccgcggtggcctgtaagaaggcctgcatgctgggccagtga

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