KEGG   Panthera pardus (leopard): 109268670
Entry
109268670         CDS       T06062                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad00480  Glutathione metabolism
ppad00980  Metabolism of xenobiotics by cytochrome P450
ppad00982  Drug metabolism - cytochrome P450
ppad00983  Drug metabolism - other enzymes
ppad01100  Metabolic pathways
ppad01524  Platinum drug resistance
ppad05200  Pathways in cancer
ppad05204  Chemical carcinogenesis - DNA adducts
ppad05207  Chemical carcinogenesis - receptor activation
ppad05208  Chemical carcinogenesis - reactive oxygen species
ppad05225  Hepatocellular carcinoma
ppad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    109268670 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    109268670 (MGST1)
   00982 Drug metabolism - cytochrome P450
    109268670 (MGST1)
   00983 Drug metabolism - other enzymes
    109268670 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109268670 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    109268670 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    109268670 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    109268670 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    109268670 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    109268670 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    109268670 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ppad02000]
    109268670 (MGST1)
Enzymes [BR:ppad01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     109268670 (MGST1)
Transporters [BR:ppad02000]
 Other transporters
  Pores ion channels [TC:1]
   109268670 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 109268670
NCBI-ProteinID: XP_019307636
Ensembl: ENSPPRG00000011654
UniProt: A0A9V1FRA3
LinkDB
Position
Unknown
AA seq 155 aa
MVDLTELMENEVFMAFASYTTIILSKMMFMSTATAFFRLTRKVFANPEDCVGFGKGENAK
KYLRTDDKVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAILHFRLFVGARIYHTVA
YLTPLPQPNRALAFFLGYGVTFSMAYRLLKSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggttgacctcactgagcttatggaaaatgaagtattcatggcctttgcttcctataca
acgattattctttcaaaaatgatgtttatgagtactgcaactgcattctttagattgaca
agaaaggtttttgccaacccagaagactgtgtaggctttggcaaaggagaaaatgccaag
aaatatcttcggacagatgacaaagtggaacgtgtgcgaagagctcacctgaatgacctt
gaaaacattgtgccatttcttggtattggccttctgtattccttgagtggtccagatctc
tctacagccatcctgcacttcagactctttgttggagcacggatctaccacacagtcgcg
tatttgacaccccttccccagccaaatcgtgctttggctttctttcttggctatggagtt
actttttcaatggcttacaggttgctaaagagtagattgtacctgtaa

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