Panthera pardus (leopard): 109269905 Help Entry 109269905         CDS       T06062                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism ppad  Panthera pardus (leopard) Pathway ppad04064   NF-kappa B signaling pathway ppad04066   HIF-1 signaling pathway ppad04145   Phagosome ppad04151   PI3K-Akt signaling pathway ppad04217   Necroptosis ppad04613   Neutrophil extracellular trap formation ppad04620   Toll-like receptor signaling pathway ppad04621   NOD-like receptor signaling pathway ppad04936   Alcoholic liver disease ppad05132   Salmonella infection ppad05133   Pertussis ppad05134   Legionellosis ppad05135   Yersinia infection ppad05140   Leishmaniasis ppad05142   Chagas disease ppad05144   Malaria ppad05145   Toxoplasmosis ppad05146   Amoebiasis ppad05152   Tuberculosis ppad05161   Hepatitis B ppad05162   Measles ppad05164   Influenza A ppad05170   Human immunodeficiency virus 1 infection ppad05171   Coronavirus disease - COVID-19 ppad05205   Proteoglycans in cancer ppad05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ppad05321   Inflammatory bowel disease ppad05323   Rheumatoid arthritis ppad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppad00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     109269905 (TLR4)    04066 HIF-1 signaling pathway     109269905 (TLR4)    04151 PI3K-Akt signaling pathway     109269905 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     109269905 (TLR4)   09143 Cell growth and death    04217 Necroptosis     109269905 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     109269905 (TLR4)    04620 Toll-like receptor signaling pathway     109269905 (TLR4)    04621 NOD-like receptor signaling pathway     109269905 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     109269905 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109269905 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109269905 (TLR4)    05161 Hepatitis B     109269905 (TLR4)    05171 Coronavirus disease - COVID-19     109269905 (TLR4)    05164 Influenza A     109269905 (TLR4)    05162 Measles     109269905 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     109269905 (TLR4)    05135 Yersinia infection     109269905 (TLR4)    05133 Pertussis     109269905 (TLR4)    05134 Legionellosis     109269905 (TLR4)    05152 Tuberculosis     109269905 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     109269905 (TLR4)    05144 Malaria     109269905 (TLR4)    05145 Toxoplasmosis     109269905 (TLR4)    05140 Leishmaniasis     109269905 (TLR4)    05142 Chagas disease     109269905 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     109269905 (TLR4)    05321 Inflammatory bowel disease     109269905 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109269905 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109269905 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ppad04131]     109269905 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:ppad04054]     109269905 (TLR4)    04090 CD molecules [BR:ppad04090]     109269905 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:ppad00536]     109269905 (TLR4) Membrane trafficking [BR:ppad04131]  Endocytosis   Phagocytosis    Toll-like receptors     109269905 (TLR4) Pattern recognition receptors [BR:ppad04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    109269905 (TLR4) CD molecules [BR:ppad04090]  Proteins   109269905 (TLR4) Glycosaminoglycan binding proteins [BR:ppad00536]  Hyaluronan   Cell surface receptors    109269905 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_9 LRR_5 LRR_NXF1-5 LRR_6 ThsB_TIR LRR_LRWD1 LRR_R13L1-DRL21 LRR_EndoS Motif Other DBs NCBI-GeneID:  109269905 NCBI-ProteinID:  XP_019309576 Ensembl:  ENSPPRG00000011574 UniProt:  A0A9V1FUS1 LinkDB All DBs Position Unknown AA seq 833 aa AA seqDB search MMPPTRLAGTLIPAMAFLSCLRPESWDPCVEVVPNITYQCMDLNLHKIPDNIPSSTKDLD MSFNPLSHLGSHSFSNFPELQVLDLSRCEIQIIEDDAYQGLNHLSILILTGNPIQRLFPG AFSGLSSLQTLVAVETNIASLEDFPIGHLKTLKELNVAHNLIHSFKLPEYFSNMSNLEYL DLSNNKIQNINHKDLQVLHQKPLLNLSLDLSLNPLDFIQPGAFKEIKLRELTLRSNFNST DVMKASIQGLAGLQIHQLVLGEFKNERNLERFDKSILEGLCNLIIEKFRIAYFDKFSEDA IDSFDCLANVSTISLVHLYFNGLKQLPKNLGWQRLELVNCEFEQFPTWKLDSLKELVFSA NEVGNTFTQVKLESLEFLDLSRNDFSFKSCCSERDLGTTRLKHLDLSFNNIITISSNFLG LEQLEYLDFQRSSLKQVSDFSVFLPLKNLRYLDISYTHTQVAFHGIFNGLISLQILKMAG NSFQDNFLPNIFMELTNLTILDLSDCQLEQVSQVAFNSLPKLQLLNMSHNHLLSLDTLPY EPLHSLQTLDCSFNRIVASKEQELRHFPSNLSSLNLTRNDFACVCEHQSFLQWVKDQRQL LVEVEQMVCAKPLDMQGMPMLNFRNATCQVSKTIITVSVFTALLVSLVVVLVYKFYFHLM LLAGCKKYSRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLL RQQVELYRLLNRNTYLEWEDSVLGRHIFWRRLRKALLDGKPRSPEGMADAEGS NT seq 2502 nt NT seq  +upstreamnt  +downstreamnt atgatgcctcctacccgcctggctgggactctgatcccagccatggccttcctctcctgc ctgagacctgagagctgggacccttgtgtggaggtggttcctaacattacttaccaatgc atggacctgaatcttcacaaaatccccgacaacatcccctcatcaaccaaggacctggac atgagctttaaccccctgagtcatttaggcagccatagtttctccaacttcccagaactg caggtgctggatttatccaggtgtgaaattcaaataattgaagatgatgcatatcagggc ctaaaccacctctccatcttgatattgacaggaaatcctatccagaggttattcccagga gctttttctggactatcgagtttacagacgctggtggctgtggagacaaatatagcatct ctagaggacttccccattggacatctcaaaacgttgaaagagcttaatgtggctcacaat cttatccattccttcaaattacctgaatatttttctaacatgtccaaccttgagtatttg gatctttccaataacaagatccaaaatattaatcataaagacttacaagttctacatcaa aagcctctactcaacctttctttagacttgtccctaaaccctttagactttatccaacca ggtgcctttaaagaaattaagctccgtgaactgactttgagaagtaattttaatagtaca gatgtaatgaaagcttctattcaaggtctggcaggcttacagatccatcagttggttctg ggagaatttaaaaatgaaaggaacttggaaagatttgacaaatctatcctggagggactg tgcaatttgatcatagaaaaattccggatagcatactttgacaagttctcagaggatgct attgactcatttgattgtttggcaaacgtttctaccatttctctggtgcatctgtatttc aacgggctaaaacagctccctaaaaatctcggatggcaacggttagaattggttaactgt gaatttgaacaatttcccacatggaagctggactctctcaaggagcttgttttctctgcc aatgaagttgggaacacttttactcaggttaagttggaaagccttgagtttctagatctc agtagaaatgactttagtttcaagagttgctgttctgagagagatttggggacaaccaga ctgaagcatttagatctaagcttcaacaatattattaccataagttcaaacttcttgggc ttagaacagttagaatatctagatttccagcgttccagtttgaaacaggtcagtgatttt tcagtattcctacccctcaaaaacctccgttaccttgatatttcttacactcacacccaa gttgccttccatggcatcttcaatggcttgatcagcctccaaatcttaaaaatggctggc aattctttccaggacaacttccttccaaatattttcatggagctgactaacttgaccatt ctagacctctctgattgtcagctggaacaggtgtcccaagtggcatttaactcactccct aaacttcagttgctaaatatgagtcacaaccacctcttatcattggatacacttccttat gaaccacttcactccctccagactctggactgcagttttaaccgtatagtggcctctaag gagcaagaactacggcattttccaagtaatctatcttccttaaatcttactcggaatgat tttgcttgtgtttgtgaacaccagagtttcctgcagtgggtcaaggaccagaggcagctc ttggtggaagttgaacagatggtgtgtgcaaaacctttggacatgcagggcatgcccatg ctgaattttaggaatgctacctgtcaggtgagcaagaccatcattactgtgtcggttttc actgcactcttggtttctctggtggtggttctggtgtataagttctatttccacctgatg cttcttgctggctgtaaaaagtatagcagaggtgaaagcacctatgacgccttcgttatc tactcaagccaggacgaagattgggtgaggaatgaattggtaaagaacttggaggagggg gtgcccccttttcagctctgccttcactacagagactttattcctggtgtggccatcgcc gccaacatcatccaggaaggtttccataaaagccggaaggttatcgtcgtggtgtcccag cactttatccagagtcgatggtgcatctttgagtatgagattgcccagacttggcagttt ctgagcagccgtgccggcatcatcttcatcgtcctgcagaagttggagaagtccctgctg cggcagcaggtggagctgtatcgccttctcaacaggaacacctacctggagtgggaggac agtgtcctggggaggcacatcttctggagacgactcagaaaagccttgctggatggtaaa ccacgcagtccagaaggaatggcagatgcagaaggcagctag

DBGET integrated database retrieval system