KEGG   Panthera pardus (leopard): 109270084
Entry
109270084         CDS       T06062                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04010  MAPK signaling pathway
ppad04060  Cytokine-cytokine receptor interaction
ppad04068  FoxO signaling pathway
ppad04144  Endocytosis
ppad04218  Cellular senescence
ppad04350  TGF-beta signaling pathway
ppad04371  Apelin signaling pathway
ppad04380  Osteoclast differentiation
ppad04390  Hippo signaling pathway
ppad04520  Adherens junction
ppad04659  Th17 cell differentiation
ppad04926  Relaxin signaling pathway
ppad04933  AGE-RAGE signaling pathway in diabetic complications
ppad05142  Chagas disease
ppad05161  Hepatitis B
ppad05166  Human T-cell leukemia virus 1 infection
ppad05200  Pathways in cancer
ppad05210  Colorectal cancer
ppad05212  Pancreatic cancer
ppad05220  Chronic myeloid leukemia
ppad05225  Hepatocellular carcinoma
ppad05226  Gastric cancer
ppad05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109270084 (TGFBR1)
   04350 TGF-beta signaling pathway
    109270084 (TGFBR1)
   04390 Hippo signaling pathway
    109270084 (TGFBR1)
   04371 Apelin signaling pathway
    109270084 (TGFBR1)
   04068 FoxO signaling pathway
    109270084 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    109270084 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    109270084 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    109270084 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    109270084 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    109270084 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    109270084 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109270084 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109270084 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109270084 (TGFBR1)
   05212 Pancreatic cancer
    109270084 (TGFBR1)
   05225 Hepatocellular carcinoma
    109270084 (TGFBR1)
   05226 Gastric cancer
    109270084 (TGFBR1)
   05220 Chronic myeloid leukemia
    109270084 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109270084 (TGFBR1)
   05161 Hepatitis B
    109270084 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    109270084 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    109270084 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    109270084 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109270084 (TGFBR1)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     109270084 (TGFBR1)
Protein kinases [BR:ppad01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   109270084 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase
Other DBs
NCBI-GeneID: 109270084
NCBI-ProteinID: XP_019309907
Ensembl: ENSPPRG00000012591
UniProt: A0A9V1FVC3
LinkDB
Position
Unknown
AA seq 509 aa
MQISEVRVWENVHHRMEEAVAAGRYWGLEAKGDQALQCFCHLCTKDNFTCVTDGLCFVSV
TETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGPFS
GKPSSGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEG
TTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIF
SSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR
YTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGL
AVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR
CSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMREC
WYANGAARLTALRIKKTLSQLSQQEGIKM
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgcagatttcagaagtgagagtgtgggaaaatgtgcatcatagaatggaggaagctgta
gctgctggtagatattggggcctggaagcaaaaggtgaccaagcattacagtgtttctgc
cacctttgtacaaaagacaattttacttgtgtgacagatgggctctgctttgtctctgtc
acagagaccacagacaaagttatacacaatagcatgtgtatagctgaaattgacctaatt
ccccgagacaggccgtttgtgtgtgcaccgtcttcaaaaaccggctctgtcactacaacg
tattgctgcaatcaggaccactgcaataaaatagaactcccgactgttggccctttttca
ggaaagccatcatctggccttggtcccgtcgaattggcagctgtcattgctggaccagtc
tgcttcgtctgcatctcactcatgttaatggtttatatctgccataatcgtactgtcatt
caccatcgagtgccaaacgaagaggatccttccttagatcgtccttttatttcagagggc
actacgttgaaagatttaatttatgatatgacaacatcgggttctggatcaggtttacca
ttgctcgttcagagaacaattgcaagaactattgtgttacaagaaagtattggcaaaggt
cgatttggagaagtttggcggggaaaatggcgaggagaagaagttgctgtcaaaatattc
tcctctagagaagaacgctcatggttccgtgaggccgagatttatcagaccgtaatgtta
cgccatgaaaacatcttgggatttatagcggcagacaataaagacaacggtacatggact
cagctctggttggtgtcagattatcatgagcatggatccctttttgattatttgaacaga
tacacagtgaccgtggaaggaatgataaaactcgctttgtccacagcaagtggacttgcc
catcttcacatggagattgttggtacccaagggaaaccagccattgctcatagagatttg
aagtccaagaatatcttagtaaagaagaatggaacttgctgcattgcagacttaggactg
gcagtaagacacgattcagccacagatacgattgatattgctccaaaccacagagtggga
acaaaaaggtacatggcccccgaagttctagatgattccataaacatgaaacactttgaa
tccttcaaacgtgctgacatctatgcaatgggcttagtattctgggaaatagctcgacga
tgttccattggtggaattcatgaagattaccagctgccttattatgatcttgtaccttct
gatccatcagttgaagaaatgaggaaagttgtttgtgaacagaagttaaggccaaatatt
ccaaacagatggcagagttgtgaagccttgagagtaatggctaaaattatgagagaatgt
tggtatgccaacggagctgctagacttacagctttgaggattaagaaaacattgtcacaa
ctcagtcaacaggaaggcatcaaaatgtag

DBGET integrated database retrieval system