Panthera pardus (leopard): 109270364
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Entry
109270364 CDS
T06062
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00260
Glycine, serine and threonine metabolism
ppad00630
Glyoxylate and dicarboxylate metabolism
ppad00670
One carbon pool by folate
ppad01100
Metabolic pathways
ppad01200
Carbon metabolism
ppad01230
Biosynthesis of amino acids
ppad01240
Biosynthesis of cofactors
ppad01523
Antifolate resistance
ppad04981
Folate transport and metabolism
Module
ppad_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
109270364 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
109270364 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
109270364 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
109270364 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109270364 (SHMT2)
Enzymes [BR:
ppad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
109270364 (SHMT2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
109270364
NCBI-ProteinID:
XP_019310400
UniProt:
A0A9V1FW78
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRWGHLGRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPTFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDTETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatggggtcatctgggc
aggatggccatacggtgccaacacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaagagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagagagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccttggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattatggaggagcagaggtagtggatgaaattgagctgctgtgtcag
cgccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtccagcca
tactcaggctctccggctaatctggcggcctatacagcccttctgcagcctcatgaccga
atcatggggctggacttgcctgatgggggccatcttactcacggctacatgtctgatgtc
aagcggatctcggccacatccattttctttgagtctatgccctataagttaaatcccaaa
actggcctcatcgactatgaccagctggcactgaccgctcggcttttccgaccacggctc
attatagctggtaccagtgcctacgctcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctcctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcacgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaggggatgcaggctgtggac
cccaagaccggccgggagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccgtccctgcagggggggccccacaaccatgccattgctgcagtggctgtggccttaaag
caggcctgcacccccacgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggccgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaatcac
ctagtgctggtggacctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaacttgtatccatcacagccaacaagaacacctgtcccggagaccgaagtgccatcaca
cctgggggcctgcggcttggggccccagccttgacatctcgacagttccgtgaggatgac
ttccggagagttgtagactttatagatgaaggggtcaacatcggcttggaggtgaagagc
aaaactgccaaactccaggatttcaaatccttcctgctcaaggacacggaaaccagtcat
cggctggccgacctccggcaacgggtggaacagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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