KEGG   Panthera pardus (leopard): 109270733
Entry
109270733         CDS       T06062                                 
Symbol
ACVR2A
Name
(RefSeq) activin receptor type-2A isoform X1
  KO
K04670  activin receptor type-2A [EC:2.7.11.30]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04060  Cytokine-cytokine receptor interaction
ppad04350  TGF-beta signaling pathway
ppad04550  Signaling pathways regulating pluripotency of stem cells
ppad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    109270733 (ACVR2A)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    109270733 (ACVR2A)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    109270733 (ACVR2A)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    109270733 (ACVR2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109270733 (ACVR2A)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     109270733 (ACVR2A)
Protein kinases [BR:ppad01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   109270733 (ACVR2A)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Activin_recp
Other DBs
NCBI-GeneID: 109270733
NCBI-ProteinID: XP_019311035
Ensembl: ENSPPRG00000013771
UniProt: A0A9V1FXH3
LinkDB
Position
Unknown
AA seq 521 aa
MGAAAKLAFAVFLISCSSGAILGRSETQECIFYNANWERDRTNRTGVEPCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNERFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQHAFH
IMIEDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNE
YEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHI
AETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKS
AGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYM
LPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA
GCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgggagctgctgcaaagttggcgtttgccgtctttcttatctcttgttcttcaggtgct
atacttggtagatcagaaactcaggagtgtattttctataacgctaattgggaaagagat
agaaccaatcgaactggtgttgaaccctgttatggtgacaaagataaaaggcgacattgt
tttgctacctggaagaatatttctggttccattgaaatagtgaagcaaggttgttggctg
gatgatatcaactgttatgacaggactgattgtatagaaaaaaaggacagccctgaagta
tatttttgttgctgtgagggcaatatgtgtaacgaaaggttttcttactttccagagatg
gaagttacacagcctacttcgaacccagttacacctaagccaccctattacaacatactg
ctctattccttggtgccacttatgttaattgcggggattgttatttgtgcattttgggtg
tacaggcatcataagatggcctaccctcctgtacttgttccaactcaacacgcctttcat
ataatgatagaggacccaggaccacccccaccttctccgttactaggtttgaagccacta
cagttattagaagtgaaagcaaggggaagatttggttgtgtttggaaagcccagttgctc
aatgaatatgtagctgtgaaaatatttccaatacaggacaaacagtcatggcaaaatgaa
tatgaagtttatagtttacctggaatgaaacatgagaacatattacagttcattggtgca
gaaaaacgaggcaccagtgttgatgtggacctttggctaatcacagcatttcatgaaaag
ggttcactgtcagactttctaaaggctaatgtggtctcttggaacgaattgtgtcatatt
gcagaaaccatggcaagaggattggcatacttacatgaggatatacctggcctaaaagat
ggccacaaacctgccatatctcacagggacatcaaaagtaaaaatgtgctgttgaaaaac
aacctgacagcttgcattgcagactttgggttggcgttaaaatttgaggctggcaagtct
gctggtgatacccatggacaggttggtacccggaggtatatggctccagaggtattagag
ggtgctataaacttccaaagggatgcatttttgaggatagatatgtacgccatgggatta
gtcctgtgggaactggcttctcgctgtactgctgcagatggacctgtagatgaatacatg
ttgccatttgaggaggaaattggccagcatccatctcttgaagatatgcaggaagttgtt
gtgcataaaaaaaagaggcctgttttaagagattattggcagaaacatgctggaatggca
atgctctgtgaaacgatagaagaatgttgggatcatgatgcagaagccaggttatcagct
ggatgtgtaggtgaaagaattactcagatgcaaagacttacaaatatcattactacagag
gacattgtaacagtggtcacgatggtgacaaatgttgactttcctcccaaagaatctagt
ctatga

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