Panthera pardus (leopard): 109271765
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Entry
109271765 CDS
T06062
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00270
Cysteine and methionine metabolism
ppad00480
Glutathione metabolism
ppad01100
Metabolic pathways
ppad01240
Biosynthesis of cofactors
ppad04216
Ferroptosis
Module
ppad_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
109271765 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
109271765 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
109271765 (GCLC)
Enzymes [BR:
ppad01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
109271765 (GCLC)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
109271765
NCBI-ProteinID:
XP_019312975
Ensembl:
ENSPPRG00000008679
UniProt:
A0A9V1G0W5
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPLEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFMETFPEDEEAARASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTVVDGYGKAQNTSELTTEDYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKRDSVITDEMNYS
LILKCNQIADELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggcacacctggacaaccgtatggaggaacaatgtccgagttcaacacagtt
gaagacaacatgagaaaacgccggaaggaggcaacctctttattaggagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccagagttt
aaacccaatccgctcgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcatccccgcttcagtaccctgacaagaaatatccgacacaggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatggaaaca
tttcctgaggatgaggaggcagcaagggcttccaagcctgatcatatttacatggatgcc
atgggatttgggatgggtaattgctgtcttcaggtaacgttccaagcctgcagcatatct
gaggctagatacctttatgatcagctggccaccatctgtccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
agctataggatcagtaaatcccgatatgattcaatagacagttacttatctgagtgtggg
gagaaatacaatgacattgacttgacaattgataaagaaatctacgaacagctgctgcag
gaaggcattgatcatctcctggcccagcatgtcgctcatctcttcatcagagacccactg
actctattcgaagagaaaatacacttggatgatgccaatgaatcggaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactctgacatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtatttgtggtgctgcttacaagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaacatgaaagttgcacagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtgggaacactgtggtggatggc
tacgggaaggcccagaacacctcggaactgaccacggaggactacaccctgatgagcata
gacaccatcatcaacgggaaggagggtgtgtttcctgggctgatcccgattctgaactct
taccttgaaaacatggaggtggatgtggacactagatgtagtattctgaactacttaaag
ctaattaagaagagagcatctggagaactaatgacagttgccagatggatgagagagttt
atctccaaccatcctgactataagcgagacagtgtaatcactgatgaaatgaactatagc
ctcatcttaaagtgtaaccaaattgcagacgaattgtgtgagtgcccggagttacttgga
ccagcgtttaggaaagtgaaatacagtggaagtaaaacggacccttccaactga
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