Panthera pardus (leopard): 109271784 Help Entry 109271784         CDS       T06062                                  Symbol DST Name (RefSeq) dystonin isoform X1   KO K10382   dystonin Organism ppad  Panthera pardus (leopard) Pathway ppad04382   Cornified envelope formation Brite KEGG Orthology (KO) [BR:ppad00001]  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     109271784 (DST)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:ppad04812]     109271784 (DST) Cytoskeleton proteins [BR:ppad04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     109271784 (DST) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin SR_plectin_7 Plectin CH GAS2 Spectrin_2 Spectrin_3 SH3_10 Spectrin_SYNE1 EF-hand_1 Spectrin_4 EF-hand_7 EF-hand_6 EF-hand_5 Spectrin_1st_PEPL Laminin_II EH Motif Other DBs NCBI-GeneID:  109271784 NCBI-ProteinID:  XP_019313011 Ensembl:  ENSPPRG00000023161 UniProt:  A0A9V1G184 LinkDB All DBs Position Unknown AA seq 7826 aa AA seqDB search MIAAAFLVLLRPYSIQCALFLLLLLLGTIATIVFFCCWHRRLQKGRHPMKSVFSGRSRSR DAVMRSHHFRSEVIYLARTLKGFRASPRHLRRRAAAAAAARLEEAKPVVEVHHQSEQEIS VRKRRIKKNSRVQPEFYHSVQGASTRRPSSGNASYRCSMSSSADFSDEDDFSQKSGSASP APGDTLPWNLPKHERSKRKIHGGSVLDPAERAVLRIADERDKVQKKTFTKWINQHLMKVR KHVNDLYEDLRDGHNLISLLEVLSGDTLPRERDFLKTLRLVSATEACEYEQHEDVEDEDK GPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS DIHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDM NTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEG GEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSERTFPNNPVELKALYNQYLQFKETE IPPKETEKSKIKRLYKLLEIWIEFGRIKLLQGYHPNDIEKEWGKLIIAMLEREKALRPEV ERLEMLQQIANRVQRDSVICEDKLILARNALQSDSKRLESGVQFQNEAEIAGYILECENL LRQHVIDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSKGRMLTTEQTKLMIS GITQSLNSGFAQTLNPSLNSGLTQGLTPSLTPSSVTSGLSSGLTSRLTPSVTPAYTPGFP SGGLVPSFSSGVEANSLQTLKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQ VQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHR LESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEEEEVAYDWSERNNNIARKKE YHAELMRELDQKEENIKSVQEIAEQLLSENHPARLTIEAYRAAMQTQWSWVLQLCQCVEQ HVKENTAYFEFFNDAKEATDYLKNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQ YKSTVASLMGRAKTIIQLKPRNPDCPLKTSIPIKAICDYRQIEITIYKDDECVLANNSHR AKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQNVLTLWHESHINMKSVVSW HYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQIFSGSDITQLEK EVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNIRLRLESCEDRLIRQIRTPLERDDL HESVFRITEQEKLKKELERLKDDLGTITNKCEEFFSQAATSASVPTLRSELGVVIQNMNQ VYSMSSTYIDKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLISTLKQWR SEVDEKREVFHALEDELQKAKAISDEMFKTYKERDLDFDWHKEKADQLVERWQNIHVQID NRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQKMLVS EIEMKQSKMDECQKYAEQYSTTVKDYELQTMTYRAMVDSQQKSPVKRRRMQSSADLIIQE FMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNITKT LRDDEKAGKSPFSKQKISSEEISTKKEQVSEALQTMQLFLAKHGDKMTDEERNELEKQVK SLQESYNSFFSESLKQLQESQTLGDTKVEEKLAKVIAGTIDETTGEVLSVFQAVLRGLID YDTGIRLLETQLMISGLISPELRKCFDLQDAESHGLIDEQVLCQLKELNRAKEIISTMSS TTIPVLEALAQGMISESMAIRVLEILLSTGFLVIPATGEQLTLQKAFQQNLVSSALFSKV LERQNMCKDLIDPCTAEKVSLVDIIQRSILQENTGMRLLPVRPQEGGRITLKCGRNISIL RAAHEGLIDRETMFRLLGAQLLSGGLINCNSGQRMTVEEALMEGVIDRDTANSILTYQVQ TGGIIHSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQE LITNELAYKILNGRQKIAALYIPETSQVIGLDVAKQLGIIDNNTASILKSIILPDKMPDL GDLEACKNARRWLSFCKFQPSTVHDYRQEEDVFDGEEPVATQSSEQTKKLFLSYLMINSY MDANTGQRLLLYDGDLNEAVGMLLEGSSAEFEDTPVKECLDVLGLPGVFLNNAPSRGRDD SVASLTSFDKCYCREPKCKEIPEEKKNAVDEEFNEMGNNITSGEYHQSENLANIIATDHK VKNSSSVRVPNSVSCLTQPGLVPVSMLRQDSENILKNCENQSQVGINEDEDECSHSKHTQ NFASESITNPIMKSKTSRTSDLNKKENEDNISRDLTTFDYSPRLSALLSHDKLRNDQESL NDLHTTESHGNKCKDSTLSFSDQTMLSGQRMGEKFQDQFLGIAAINISLQGEHCQQNPLN IGDSDPQVPSHNDKYNSDIYGEDEEPHAASQQKPEDGKNESQVEEYSCATTPQGDTDNAN PSRICGTSLLEETVCASDYETSLLDDQHSVTETDTDSDDDFYDTPLFEDDDHDSLLLEGD DCDCLQPEDYATLQEENDGAAPSGDVFYDVSKEIENSVVTQGALVDSLSVREDTQSPQGF LTGTEKAEFDSGERVRSNSADSDKDNGQLLETVSESESANSLEGDECDSLADYEIVEGKE SFSASLTFDDTGCWRRRQEEHIAEQEFKSDTEHLDSVQSEESYGYYVCDSNDQDDDDDSD DDDGDSEEGVEGENGKPPYQDEGMNSQLRATIVSEKENGRENQSVTKVILPDKAHNYSSS EKQQSVNVLQLESTSKNSLVTERSNLPEYTPEAVGKSKEDLLNHDMALKDILLTITKDTE SENTSGSVDVLNNTNTCSTSEVDKDPMNVKFQLIQEPESTDTVKGGDQYFDNVTVQDSSP FDKIICPEPDLTGKPAEESHLSSVACVSAKDHQVPERGLVKKNSGQNGILTEDETYVHKM CSGKGDVLREGLEEESRSLRPLPGESTRKNLDLVNDQFPFPAVTDSEEHNVKGSLKKTTV TLADEPQNLQTVVSKSPVQFENLEEIFESSISKVISDDILSDIPLSEGNTDTEKDSFTDG PDKESDLFTYLNHCAKDVKAKDVLKPNGDIPSCVLMASPAVKEDIQFGINNAKEKTALTQ EVSPLNETAQQNDLCSNESASEGGTEVGHFTPEGNESTLSIFPLKNVEDFGENTDFVSPE LCTNVIRNDNSSNPLSTDYLFSEIHGKMETIEQQQRKEQALSLGLQEKEVHIPESSQVFV EDVESRLEEGPMNPQEVGESPVCSDTEILIQSLIERVNTLQLAKEASSVPSDSKIGDCSR VSPMNNSPELKAESRDDPFCIANLKSEFLLNILKQNQYSQKITGAFELMKELTQMEYELE KRGITSKVLPLQLENIFYKLLADTYSEKVEQVRDLNQKSSTASEVVDEKSHILDDLKGEE GNHCSHNLQNLKDTGLENPTACASALPSDEKLGELCSDIPEHLESIAGSKRMTSGDSSME QFSSELQQCLQHTSKMHEYLALLQDMKPPLDNQESLDNNLETLRNQLKQLETFELGLAPI AVILRKDMKLAEEFLNSLPSHFPREQLEELSLGHQSLQTAFSSLSSVSSERMKRVMLAID SEMSKLAVSHEEFLQKLELFSHWISEKNKSVKDIEIVNVQDTEHVKKSLQLLKNVLKDLG PTKVQLETTAFDVQFFISEYAQDLSPNQSKQLLRLLNTTQKCFLDVQESVTTQVERLETQ LQLEQDLDDQKIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFVIGDGTVELKEYQSK QEELQKDMQGSAQALAEIVKNTENFLKENGEKLSQEDKALIEQKLNEAKLKCEQLNLKAE QSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGMRQRQVIE QNGTHFQEGDGKSAIGEEDEVNGNLLETDVDGQVGTTEENLNQQYQKVKAQHEKIVSQHQ AVLMATQSAQALLEKQGHYLSPEEKEKLQKNMKELKTHYETALAESEKKMKLTHSLQEEL EKFDADYSEFEHWLQQSEQELENLEAGADDLSGLMTKLKRQKSFSEDVISHKGDLRYITI SGNRVLEAAKSCSRRSGSSKADQDNIDTSATHREVQSKLDHATDRFRSLYSKCNVLGNNL KDLVDKYQHYEDASCGLLSGLQACEVTASKHLSEPIAVDPKNLQRQLEETKALQGQISNQ QVAVEKLKKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYDDLSKSVNERNEKLQITLTRS LSVQDGLDEMLDWMGSVESSLKEQGQVPLNSAALQDVISKNIMLEQDIAGRQSSINAMNE KVKKFMETSDPSTASSLQAKMKDLSARFSEASHKHKEKLAKMEELKTKVELFENLSEKLQ TFLETKTRALTDTDVPGKDVSELSQYMQESTSEFLEHKKDLEVLHSLLKEISSHGLPGDK ALVFEKTNNLSKKFKEMEHTIKQKKEAVSSCQEQMDAFQVLVKSLKSWIEETTERVPIVQ PSFGAEDLGKSLEETKKLQEKWSSKTPEIQKVNNSGISLCNLISAVTTPAKAIAAVKSGG IINGEGAATDTQEILANKGLTSIKKDMTDISHGYEDLGLLLKDKISELNSKLSKLQKAQE ESSAMMQWLQKMNKTATKWDQAPTPTDAEAVKTQVEQNKSFEAELKQNVNKVQELKDKLT ELLEENPDTPEAPKWKQMLTEIDSKWQELNQLTVDRQQKLEESSTNLTQFQTVEAQLKQW LVEKELMVSVLGPLSIDPNMLNTQRQQVQILLQEFDTRKPQYEQLTAAGQSILSRPGEHP SFHGIVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIIKSTQYQSLLRSLSDKLSDLDNKLI TSAAVSAHPDAMNQQLEAAQKMKQELEQEMKQINVAQALCEDLSALVKEEYLKAELSRQL EGIIKSFKDIEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKCPPISAKLD VLESLIKDQKDFSKTLSAQSSIYEKTIAEGENLLLKTQGSEKAALQLQLNSIKTNWDGFN KQVKEREDRVKDSLEKALKYREHVETLRPWIDKCQNNLEEIKFCLDPAETENSVAKLQSL QKEMNQHFGMVELLNNAANSLLSVCEVDKEAVTDENKSLIQKVDMVTEQLHSKKFSLENM AQKFKEFQEVSKEAKRQLQCAKEQLDVYDSLGPQAYSNKYLTVLQTQQKTLQTLKHQVDL VKGLAQDLVVEASDSKGTSDVLLQAETLAQEHSALSQQVDERCSFLETKLQGIGHFQNTI REMFSQFAEFDDELDSMAPVGRDVETLQKQKEDIKAFLKKLEALIASNDNANKTCKRMLA MEETSPDLVGIKRDLEALSKQCNKLLDRAQAREGQVEGTVERLEEFYSKLKEFSTLLQKA EEHEESQGPVGMETETINQQLNVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAKSTSTQ GLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMADTEELVANQKP PSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIAATAEPADKAKILKQLSLLDS RWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKKLANCEPIGTQASKLEEQ IAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLDSSQVWYIEIQEKSHS RSELLQQALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSPEGLWKQQSELRVLQEDI LLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQL ARRLHSTREELCTWLDKVEVELLSYETQVLTGEAASQAQARQKELKKEAKDSKALLDSLN EVSSALLELVPWRAREGLEKMVAEDNDRYRLVSDTITQKVEEIDAAILRSQQFDQAADAE LSWITETEKKLMSLGDIRLEQDQTSAQLQLQKKFTMEILRHKDIIDELVKSGHKIMTTCS EEEKQSMKKKLDKVLKNYDAICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQRII SQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPGEGFSIQEKYV AADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEK IKEQISENKNVSVDMEKLQPLYETLKKRGEEMIARSEGTDKDISAKAVQDKLDQMVFIWE NIHTLVEEREAKLLDVMELAEKFWCDHMSLVVTTKDTQDFIRDLEDPGIDPSVVKQQQEA AEAIKEEIDGLQEELDIVVNLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWKDRVD KLEEAMQAAVQYQDGLQAIFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQ QIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLDERIINRQHKLEGALLALG QFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKA GNDLIASSAGEEASNLQNKLEILNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQ WLTDTERHLLASKPLGGLPETAREQLNAHLEICAAFDVKEETYKSLMQKGQQMLARCPKS AETIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVA SRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISV QSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIK TQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGK SVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVMNLIDNHKAFQ KELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAAL RQAEEFHSVVHALLEWLAEAEQTLRFHGALPDDEDALRTLIDQHKEFMKKLEEKRAALNK ATSMGDAVLAMCHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLE ALLAWLQWAETTLSDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRA ADPASLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALE RRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQE FIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPVTDADKIEDE VTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALD EFLVKNDPCRVHHHGSKMLRSESNSSITTTQPTIAKGRTNMELREKFILADGASQGMAAF RPRGRRSRPSSRGASPNRSTSVSSQAGQAASPQVPATSTPKILHPLTRNYGKPWLTNSKM STPCKPAECSDFSVPSAEGTPIQGSKLRLPGYLSGKGFHSGDDSGLITTAAARVRTQFAD PKKTPSRPGSRAGSKAGSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPTPRAGSRP STAKPSKIPTPQRKSPASKLDKSSKR NT seq 23481 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgcggctttcctcgtcttgctgagaccctacagcatccaatgtgccctcttc ctcttgttgcttctgctgggcaccatcgccaccatcgtcttcttttgctgctggcaccgc aggctccagaaagggaggcatccgatgaaatcggtcttttcgggtcgttcaaggagccga gatgctgttatgagatcccaccactttcgttctgaggtaatttatttagcgcgcacgctc aagggattcagagcaagccctcggcatcttagaagacgcgctgctgcggccgcagctgct cgcctggaagaggccaaacctgtggtggaagttcaccatcagagtgagcaagaaatttca gtgaggaaacgaagaatcaagaaaaatagccgagtccagccagaattctatcactccgtt caaggtgcttcaacccgaaggcctagttccgggaacgcgtcctatcgctgctctatgtct tcctctgcggatttttctgatgaagatgatttcagccagaaatctggctcggcatctcca gcgccgggagacaccttaccctggaatttgcctaaacatgagagatcaaaaagaaagatt cacgggggctcggtgctggaccccgctgagagggcagtgcttaggatagcagatgaacgg gacaaagttcaaaagaaaacgtttacaaaatggataaatcagcatctcatgaaggttcga aaacatgtgaatgatctctatgaagacttaagggatggacacaatttaatctctctttta gaggttctttcgggagataccttgccaagggagcgagattttttgaagaccttacgattg gtgagtgcaacagaagcatgcgaatatgaacagcatgaggatgtggaggatgaggataag gggccaagagaaaaaggtcggatgcgttttcacagactacagaatgtacaaattgcactt gactatttgaaaagacgccaggtgaaattagtgaatattagaaatgatgacataacagat ggaaatcccaagttgactttgggattaatatggacaataattttgcactttcagatatct gatatccatgttactggagagtcagaggatatgtctgcgaaggagagattgctactgtgg acacagcaggcaacagagggttatgctggaatacggtgtgaaaatttcactacctgctgg agagatggaaaactatttaatgccatcattcataaatacaggccggacctgatagacatg aatactgttgctgttcaaagcaaccttgcaaatttagagcacgctttttatgtagcagaa aaaattggagttataagacttctggatcctgaagatgttgatgtctcctcacctgatgaa aaatcagtaataacttatgtgtcatctctctatgatgcatttcccaaagtccctgaaggt ggcgaaggcattggtgcaaatgatgttgaagtcaaatggattgaataccagaatatggtg aactacctcattcagtggattagacaccatgtgaccacaatgtctgagagaacatttcct aataatcccgtagaactcaaggcactttataatcagtatttacagtttaaagaaacagaa attccaccaaaggagacagaaaaatcaaaaattaaacgcctatataaattattagagatt tggatagaatttggacgcatcaaactacttcaaggttatcatccaaatgacatagaaaaa gagtgggggaaactcattattgccatgcttgagagagagaaggcacttcgaccagaagta gaaaggttggaaatgttgcagcagattgccaaccgagttcaaagggacagtgtcatctgt gaagacaaactgatacttgcccgaaatgctctccagtctgattctaaaagattagaatca ggagtgcagtttcagaatgaagcagaaattgccgggtatatacttgaatgtgagaacctt ttacgccagcatgtgatcgatgtacagattcttattgatggaaaatactaccaggcagat cagttggtacagagggttgcaaaactccgcgatgaaattatggccttaaggaatgaatgt tcctcggtgtacagcaaagggcgcatgctgacgacggaacagacaaaactcatgatatca ggaattactcaaagtttaaactcaggatttgcacagaccttaaaccccagtctgaactca gggctgacccagggtttaacgccttccctgaccccttctagtgtgacatcaggcctgtca tcaggtctgacttcccgtctgactccatctgtcacgccagcttatacacctggtttccca tcaggaggattagttccaagtttcagttcaggagtagaggccaattcattacaaactctg aaactgatgcagatccgaaagccccttctgaagtcttctttgctggatcagaatttaaca gaagaggaaatcaacatgaaatttgttcaagatcttttgaattgggttgatgagatgcag gtgcagctggaccgcactgaatggggatcagatttgccaagtgttgaaagccatttagag aatcataaaaacgttcaccgagctattgaagaatttgaatctagccttaaagaagctaaa atcagtgagatccaaatgacggcacctcttaaactaacttatgcagaaaagttacaccga ttagagagtcagtatgcaaaactcttgaatacatccaggaatcaggaacggcaccttgat acactccataattttgtaactcgtgcaactaatgaacttatttggttgaatgaaaaagaa gaggaggaagttgcctatgactggagtgaaagaaataacaacatagctcggaaaaaagaa taccatgctgaattaatgagagaacttgatcaaaaggaagaaaatattaaatcagttcag gagatagcagagcagctactttcggaaaatcacccagccagactgacaattgaggcctat cgagcggcaatgcagacacagtggagctgggtcttacagctgtgccagtgtgtggagcag catgtcaaggaaaacaccgcgtatttcgagtttttcaatgatgccaaagaagctactgat tacttgaagaatctcaaggacgccattcagcggaagtacagctgtgacagatcaagcagc attcacaaactggaagacctggttcaggagtcaatggaagagaaagaagaacttttacag tataaaagcacagtagcaagcttgatggggagagcaaaaacaataattcagctgaagccg aggaatcctgactgtccactcaaaacttctattccaatcaaagctatttgtgactacaga caaattgagataaccatttacaaagatgatgaatgtgttttggccaacaattctcaccgt gcgaaatggaaggtcatcagccccactgggaatgaggctatggtcccgtctgtgtgcttc acagtccctccaccaaacaaagaagcagttgactttgcaaaccgaattgagcaacagtat cagaatgtcctgactctttggcatgagtctcacataaacatgaagagtgtagtgtcctgg cattatctgatcaatgaaattgatagaattcgagctagcaatgtggcttcaataaagaca atgttacctggtgaacatcaacaagttctgagtaacctgcagtctcgttttgaagacttt ctggaagatagccaggaatcccaaatattttcaggctcagatataacgcaactggaaaag gaggttaatgtatgtaagcagtattatcaagaacttcttaaatcagcagaaagagaggag caagaggaatctgtgtataacctgtacatctctgaagttcgaaacattagacttcggtta gagagttgcgaagatcggttgattagacagatccgcactccactggaaagagatgatttg catgaaagtgtgttcagaatcactgagcaggagaaactaaagaaagagctggagcgactt aaagatgatttgggaacaatcacaaataaatgtgaagaatttttcagtcaagcagcaacc tctgcatcagtgcccaccttacggtctgagctcggtgtggtcattcagaacatgaaccaa gtctattctatgtcttccacttacatagataaactgaaaactgttaatttggtgttgaaa aacactcaagcagcagaagcccttgtaaaactctatgaaactaaactgtgtgaagaggaa gcagttatagctgacaagaataacattgagaatctaataagtaccttaaagcaatggagg tctgaagtagatgaaaagagagaggtattccatgcattagaggatgagttgcagaaagct aaagccatcagtgatgaaatgtttaaaacctataaagaacgggaccttgattttgactgg cacaaagaaaaagcagaccaattagttgaaaggtggcaaaatattcacgttcagattgac aacaggttacgggacttagaaggcattggcaaatcactgaagtactatagagatacttat caccctttagatgattggatccagcaagttgaaactacccagagaaaaattcaggaaaat cagcctgaaaatagtaaaactctagccacacagttgaatcaacagaagatgctggtgtcc gaaatagaaatgaaacagagcaaaatggatgagtgtcaaaaatatgcagaacagtactca actacagtgaaggactatgaattacaaacaatgacctaccgggccatggtagattcacaa caaaaatctccagtgaaacgccgaagaatgcagagctcagcagatcttattattcaagag ttcatggacctaaggacccgatatactgctctggtcaccctcatgacacaatatattaaa tttgctggtgattcattaaagaggctggaagaggaggagaagtcactggaagaagaaaag aaagaacatgttgaaaaagccaaagaattacagaaatgggtatcaaatatcaccaagaca ttgagagatgacgagaaggctggaaaatctcccttctctaagcaaaagatttccagtgaa gaaatatcaaccaagaaggaacaagtatctgaagcacttcaaaccatgcagctgtttttg gcaaaacatggagacaaaatgacagatgaagaaagaaatgaattggaaaaacaagtgaaa tctcttcaagaaagttataattcattcttcagtgaatctctgaaacaactacaagaatca caaaccttaggagatacaaaggtagaggagaagctggctaaagtgattgcaggcaccatt gatgagacaactggagaagtcctgtcagtctttcaggcagttttaagaggccttattgac tatgacacaggaatcaggttgcttgagacacagctaatgatttctggtctgatttcacca gaattaagaaaatgttttgacctccaagatgccgaaagtcatggccttattgatgaacaa gttttatgccaactcaaagaactaaatcgagcaaaggagatcatttccaccatgtcatct accacaattccagtgctggaagctttggctcaaggcatgatatcagaatctatggccatc agagtgcttgagatactactttccactggctttctagttattccagccaccggagaacag ctgaccctacagaaggctttccaacagaacttggtttcttcagcgttattttctaaagtc ctggagaggcaaaatatgtgtaaggatcttattgacccctgcaccgctgagaaggtgtct ttagtagatattatacagagaagtattttacaggaaaacactgggatgcggcttctacct gtgagaccacaagaaggaggtagaataacattaaaatgtggaagaaacataagcatttta agggcggctcatgaaggtctcatagaccgggaaaccatgtttaggttattaggtgcacag ctgctttctggaggtctgatcaattgcaattctggtcagagaatgactgttgaagaagct ttgatggaaggggtgattgacagagacacggctaacagtattctcacatatcaggttcaa acaggtggaatcatccactcaaatcctgctaaacgtttaaccgtggatgaagcagtccag tgtgatctcataacttcgagcagtgctcttttggtactagaggctcagcgaggctatgtg ggactcatctggcctcactctggtgaaatatttcctacatcttcttccttgcagcaagaa ttgattacaaatgaattggcatacaaaatcctgaatggcaggcagaaaatagctgctctt 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cagttggcaaaagaagcatctagtgtgcccagtgattctaaaattggtgactgttctaga gtttcccccatgaataactcaccagaactaaaagcagagagtagagatgatccattctgt attgccaatcttaagtctgagtttctccttaatatacttaagcagaatcagtatagccag aaaattactggagcatttgaattgatgaaagaattaacccagatggagtatgagctcgag aaaagaggtattacatccaaagtacttccattgcaacttgaaaatattttctataagctg ctcgctgacacatattcagagaaagtagagcaggtcagagatctgaatcaaaaatcatcc actgcttcggaggttgtggatgaaaagtcacacattcttgatgatcttaaaggtgaagaa ggaaaccactgttcccataatttacaaaacctaaaagataccggacttgaaaacccgact gcgtgtgcatcggcattgccgagcgatgagaagctgggggagctatgcagtgatatccca gaacatctggaaagtattgcagggtcaaaacgaatgacttcaggagatagctcaatggaa caattttccagtgagttacagcagtgtttacagcacacatcaaaaatgcatgagtatttg gctttacttcaagatatgaagcccccgttagacaaccaggagtctctggataataatctg gaaacattgaggaaccaacttaaacagttagagacatttgaattgggattggctccaatt gctgttattttaagaaaagacatgaagttggcagaagagtttttaaactcccttcccagt cacttccccagagaacagcttgaggaattgagtctaggccaccaaagtttgcagactgct ttctcttccctcagcagtgtgtcttcagaaaggatgaaacgtgtcatgctcgcgattgac 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ccatcagccgagttcaaagtggtgaaggcccagatacaagagcaaaaacttctccaaaga ttgctggatgaccgcaaatcgactgtggaggtaatcaaacgtgaaggagaaaaaattgct gcaacagcagaacctgcagacaaagcaaaaattctgaagcagctgagtctcttggacagt agatgggaggcattgcttaataaagctgaaacacggaatcgtcagttggaaggtatctca gtggtagcacagcaatttcatgaaaccctagaaccattgaatgagtggcttacaaccata gaaaagaagctggcgaactgtgagcccataggaacccaagcgtctaaacttgaggaacaa attgcacagcacaaagccttagaagatgacatcatcaatcacaataaacatttacaccag gctgttagcattggccaatccttaaaggttttgagctccagggaggataaagatatggtg caaagtaaactagactcctctcaagtgtggtacattgagattcaagagaaaagtcacagc aggtctgagctcctccagcaggccttatgtaatgctaagatttttggggaagatgaagtt gagctgatgaattggctgaatgaagtacatgacaaactgagcaagctctcagtccaggat tacagccctgaggggttatggaagcagcagtctgaacttcgggttctgcaagaggacatc ctactcagaaaacaaaatgtagatcaggcattactaaatggtttagaactactgaaacaa acaacaggtgatgaagttttaatcattcaagataaattggaagccattaaagcaaggtac aaagacattactaaattaagcacggatgtagccaagaccttggagcaggcactgcagctt gccaggcgcctgcactccacacgtgaagagctctgcacctggctggacaaagtggaggtg 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ctggaacgcatcgtggagcgtttgaggcagccgccttcgatctcagctgaggtagagaag attaaggagcagatcagtgagaataagaatgtgtcagtagacatggagaagctacaacca ttgtatgaaacacttaaaaagcggggagaggaaatgattgcaagatctgagggcactgac aaagacatatctgccaaagctgttcaggataagcttgaccaaatggttttcatttgggag aacatacacacacttgtggaagaaagggaagccaaactactggatgtaatggaattagca gaaaagttctggtgtgatcacatgtcattggtcgtaaccactaaagatacacaagatttc atccgggatctggaggatcctggaattgatccctcagtagtaaaacagcagcaagaagca gcagaggccattaaggaagaaattgatggactacaggaagagctggatatagtggtcaac ctgggttctgaactcattgctgcatgtggggaacctgataaacccattgtcaagaagagt atagatgagttaaattcagcctgggattctctgaataaggcttggaaagaccgggtggac aaacttgaggaggcaatgcaggctgccgttcagtaccaggatggactacaggcaatattt gactgggtagatattgcaggtggtaaattagcttcaatgtcaccaattggaacagatctt gaaactgtcaagcagcagattgaagagctaaagcaattcaaatcagaggcctaccaacaa cagatagaaatggagagactaaatcatcaagcagagcttttgctgaagaaagtaacagaa gagagcgacaaacacactgttcaagacccattgatggagctgaaattgatatgggatagt ctggatgaaagaattatcaacagacagcataagctagaaggtgctctgttagcactgggc cagttccagcatgccctggatgagctgcttgcctggctgacacacactgagggcctgctg agtgaacagaagcctgtgggaggagaccctaaggccattgaaattgaactcgccaagcac catgtgcttcaaaatgatgtactagcccatcagtccacagtggaagccgttaacaaagca ggaaatgatctaattgcatcaagtgcaggagaagaagcaagcaaccttcagaacaagcta gagattctaaatcaacgatggcaaaatgttttggaaaaaacagaacaaaggaagcagcag ctggatggtgccttgcgccaggccaaagggttccatggtgagattgaggatttgcagcag tggctgacggacacggagcgtcatctgttagcctccaaacctctgggggggttaccggaa acagccagggagcagcttaatgcccacctggaaatctgtgctgcctttgatgttaaagaa gaaacatacaaaagtctgatgcagaaaggccagcagatgcttgcaagatgccccaaatct gcagagacaattgaccaagacattaataacttgaaagaaaaatgggaatcggtggaaacc aaactcaatgaaaggaaaactaaactggaagaggccctcaacttggcaatggagttccat aattccctccaagacttcatcaactggctaacccaggctgaacagaccctaaatgtagct tctcggccaagtcttatcttggacacagtcttgtttcaaatcgatgaacacaaggtcttc gccaatgaagtaaattctcaccgtgagcagataatagagctggacaaaactgggacccac ctgaagtatttcagtcagaaacaagacgttgtcctaattaagaatctactgatcagtgta caaagtcggtgggaaaaagtggttcagcggttagtagaaagagggagatctttggatgat gcaaggaaaagagccaagcagttccatgaagcttggagtaaacttatggagtggctagag gagtcagagaagtctttggattctgaactggaaattgccaatgatccagacaagataaaa acacagcttgcacagcataaggagtttcagaaatcactcggagccaagcattctgtctat gacaccaccaacagaacgggacgttctctgaaggagaaaacctccctggctgatgacaac ctgaaactggatgacatgctgagtgaactcagagacaaatgggataccatctgtggaaaa tctgtggaaagacaaaacaaactggaggaagccctgttattttctggacaattcaccgat gccttgcaggccctcattgattggctgtatagagttgaaccccagctggcagaagaccag cctgtccatggagacattgatttagtgatgaatctgatcgataatcacaaggctttccag aaagaactggggaagaggaccagcagcgtgcaggccctgaagcgctcggcacgagagctc atagagggcagccgagacgactcctcctgggtcaaggtccagatgcaggaactaagcaca cgctgggagactgtgtgtgcactttctatatcaaagcagacccgattggaagcagctctg cgtcaggcagaggaatttcactcggtggtgcatgccctcctggagtggctggccgaggcg gagcaaacccttcgtttccatggcgctctcccagatgatgaggatgctcttcggactctc attgatcagcataaagaattcatgaagaaactggaagaaaaaagagccgcactgaataaa gctaccagcatgggagatgctgttttggctatgtgccatcctgactccatcaccaccatt aagcactggataaccatcatccgggccaggtttgaggaggtgttggcctgggcgaagcag catcaacagagattagcaagtgctctggctgggctcattgctaaacaggaattgttggaa gctttgctggcttggctgcaatgggctgaaaccacgttgagtgataaggacaaggaagtc atcccccaggaaatcgaagaggtgaaagccctcattgcagagcaccagaccttcatggag gaaatgaccagaaaacaacctgatgtggataaagttaccaagacctacaagaggagggca gctgatcctgcctcattacagtcccatattccagtcctggataagggacgagcaggaaga aagcgcttcccagcatcaagcttatatccctctggatcacagacacaaatcgaaaccaag aatcccagggtcaacttgttggtgagcaaatggcagcaagtttggctcctcgcactggaa agaaggaggaagcttaatgatgccttggacagactggaagagctgagggaatttgctaac tttgattttgatatctggcgcaaaaaatacatgagatggatgaatcataagaaatctcga gtgatggacttcttcaggagaattgataaagatcaggatgggaaaataacccgacaagaa tttattgatggaattctttcctcaaagtttccaaccagccgcctggagatgagcgcagtt gcagacatctttgaccgagacggcgatggatacattgactactatgagtttgtagcggcc cttcatccgaataaagacgcatataaacctgtcactgacgccgacaaaatcgaggatgag gtgacaagacaagtagctaagtgtaaatgtgcaaaacggtttcaagttgaacaaatcgga gataacaaatacaggttcttcctgggaaatcagtttggggactcccagcaactgaggctc gttcgaatcctacgaagtaccgtaatggttcgtgttggaggtggatggatggcgcttgat gagttcttggtgaaaaatgatccttgcagggttcatcatcatgggagtaaaatgttacgt tcggaatcaaactcttcaattactactactcagcctactatagccaaaggaaggacaaac atggaacttcgggagaagttcattttagcagatggtgccagtcagggtatggcagccttc cggccccggggccgaagatcgcggccttcgtcacgaggagcttcacccaaccgctcaacg tctgtgtccagtcaggctggccaggcggcctctccacaggtccctgccaccagcacaccc aagattctccatcctttaacacgcaattatggtaaaccatggttgacaaacagcaaaatg tcaactccttgtaaaccagcagagtgctcagacttttccgtgccatctgcagagggaaca ccaatacaaggaagcaagcttcgacttccaggatatttatcagggaaaggcttccactct ggggacgacagtggcttgataaccaccgcagccgccagagtccgaacacagtttgctgat cccaagaagactcccagccgaccaggaagccgagccggaagcaaagctggcagcagggcc agcagccgccgaggcagtgatgcgtcagactttgacatttcggaaatccagtctgtgtgc tcagacgtggagactgtcccccagacacacaggcctacgccccgagcaggttctcggcca tccacagccaagccttccaaaatccccactccccagaggaaatcacctgccagcaaattg gacaagtcctcaaagagatag

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