Panthera pardus (leopard): 109272166
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Entry
109272166 CDS
T06062
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01522
Endocrine resistance
ppad04330
Notch signaling pathway
ppad04658
Th1 and Th2 cell differentiation
ppad04919
Thyroid hormone signaling pathway
ppad05165
Human papillomavirus infection
ppad05200
Pathways in cancer
ppad05206
MicroRNAs in cancer
ppad05207
Chemical carcinogenesis - receptor activation
ppad05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
109272166 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
109272166 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
109272166 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109272166 (NOTCH2)
05206 MicroRNAs in cancer
109272166 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
109272166 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
109272166 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
109272166 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
109272166 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_5
Ank_3
Ank_4
EGF_3
EGF_Teneurin
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
109272166
NCBI-ProteinID:
XP_019313572
Ensembl:
ENSPPRG00000009066
UniProt:
A0A9W2UK99
LinkDB
All DBs
Position
Unknown
AA seq
2471 aa
AA seq
DB search
MPALLPAPLWALLALWLCRAAPARALQCRDSYEPCVNEGICVTYHNGTGYCKCLEGFLGE
YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCALGFTGDDCQYSTAHPCFVSHPCLNGGT
CHVRSRDDYECTCQVGFTGKLCQWTDACLSHPCANGSTCTTVANQFSCRCLAGFTGQKCE
TDVNECDIPGQCQHGGTCLNLLGSYQCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG
DFTFECNCLPGFEGITCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLRGYTGPRCELDINECHSDPCQNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCVHGVCM
DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCLCPEGPHHPSCYSQ
VNECLSSPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAAVCKEAPNFESYTCLCAPGWQGQRCTVDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKCQTDMNECLSEPCKN
GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGP
FCLHEINECNSHPCLNEGVCVDGLGTYRCTCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
EKAESRCLCPSGWAGAYCDVPNVSCEVAAFHRGVSIDHLCQHSGICINAGNSHHCQCPLG
YTGSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCVDLVNHFKCSCPPGTRGLLCEENVDDCAGGPHCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPHMPCLNGGTCA
VASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEKCVHTASGPRCFCPNPQDCESGCAS
SPCQHGGSCYPQRQPPYYFCQCSPPFWGSHCELYTAPTSTPPATCLSQYCADKARDGVCD
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNS
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQ
DARSFLRALGTLLRTNLQIKRDSQGAFMVYPYYGEKSAAMKKQRMIRRSLPGDQEQEVVG
SKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPKGTQLLY
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDGEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
KKPRRPNTKSAMPTSLPNLAKEAKDAKGNRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGANPVLPS
VSQLLSHHHIVPPGSSSTGSLGRLHPVTVPADWMNRMEMNETQYNEMFSMVLAPAEGTHP
GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSISQPAGTPQPQSNCPPPVTGPVPTMY
QIPEMARLPNMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
EPPRSNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcccgccctgctccccgctcccctgtgggcgctgctggcgctctggttgtgccgcgcg
gcccccgcgcgtgcattgcagtgtcgggacagctatgagccctgtgtaaatgaaggaata
tgtgttacctaccacaatggtacaggatactgcaaatgtctggagggcttcttgggagaa
tattgtcaacatcgagacccctgtgagaagaaccgctgccagaatggggggacgtgtgtg
gcccaggccatgttggggaaagccacatgccgatgtgccctggggttcacaggtgatgac
tgtcagtactcaactgctcacccctgctttgtgtctcacccctgcctgaatggaggcacc
tgccatgtgcgtagccgggacgactatgagtgtacctgccaagttggttttacaggtaag
ctgtgccaatggaccgatgcctgcctatctcatccctgtgcaaatggaagtacctgcacc
actgtagccaaccagttctcctgcagatgcctcgcaggcttcacaggacagaagtgtgag
actgatgtcaatgagtgtgacatcccaggacagtgtcagcatggtggcacctgcctcaat
ctactgggttcctatcagtgccaatgcccccagggcttcacaggccagcactgtgacagc
ccctatgtgccctgtgcaccctccccctgtgttaatggaggcacctgccggcagactggt
gacttcacatttgaatgcaactgccttccaggttttgaagggatcacctgtgagcggaat
attgatgactgccctaaccacaagtgtcagaatggaggagtttgtgtggacggggttaat
acttacaactgccgctgcccccctcagtggacaggacagttctgcacagaggatgtagac
gagtgtctgctgcaacctaacgcttgtcagaacggaggcacctgcaccaaccgcaacggg
ggctatggctgcgtgtgtgtcaatggctggagtggagacgactgcagtgagaacatcgat
gactgcgccttcgcctcctgcactcccggctccacgtgcattgaccgcgtggcctccttc
tcttgcatgtgccctgaaggaaaggcaggtctcttgtgtcatttggatgatgcatgcatc
agcaatccttgccataagggggcactgtgtgataccaaccccctgaacgggcagtatatt
tgcacctgcccccaaggctacaaaggcgctgactgcacagaagatgtggatgaatgtgcc
atggccaatagcaatccttgtgagcatgcaggaaaatgtgtgaatacagatggtgccttc
cactgtgaatgtctgaggggctatacagggcctcgttgcgagttggatatcaatgagtgc
cattccgacccctgccagaacgatgcgacctgtctggataagattggaggcttcacgtgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgaattggagataaacgaatgtcagagc
aacccttgtgtgaacaatggtcagtgtgtagataaagtcaatcgcttccagtgtctgtgt
ccgcctggtttcactgggccagtttgccagattgatattgatgactgttccagtactccg
tgtctgaatggggcaaagtgtattgatcacccaaatggctatgaatgccagtgtgccaca
ggattcactggtgtgttgtgcgaggagaacatcgacaactgtgaccctgatccttgccac
catggccagtgtcaggatgggattgattcctacacctgcatctgcaacccggggtacatg
ggtgccatctgcagtgaccagatagatgaatgttacagcagcccttgcctgaatgatggt
cgctgcattgaccttgtaaatggctaccagtgcaactgccagccgggcacgtcaggtgtt
aattgtgaaatcaattttgatgactgtgcaagtaacccttgtgtccacggagtctgtatg
gatggcattaatcgttatagttgtgtctgctcaccgggattcacagggcagagatgtaac
atcgacattgatgagtgtgcctccaatccctgtcgcaagggtgcgacgtgcatcaacgat
gtgaatggtttccgctgtctatgccccgaggggccccatcaccccagctgctactcgcag
gtgaatgagtgcctgagcagtccctgcatccacgggaactgtaccggaggcctcagcgga
tacaagtgtctctgtgatgcaggctgggttggcatcaactgcgaagtggacaaaaatgaa
tgtctttctaacccatgccagaatggaggaacttgtgacaatctggtgaacggatacagg
tgtacttgcaagaagggctttaaaggctataactgtcaggtgaatattgatgaatgtgct
tcaaatccctgcctgaaccaaggaacctgctttgatgacataagtggctacacttgccac
tgtgtgctgccatacacaggcaagaattgtcagactgtgttggctccctgttccccaaac
ccatgtgagaatgctgctgtttgcaaagaggcaccaaattttgagagctacacctgcctg
tgtgcccctggctggcaaggtcagcggtgtacagttgacattgatgagtgtgtctccaag
ccttgcatgaaccacggtctctgccataacacccagggcagctacatgtgtgagtgtcct
ccaggcttcagcggtatggactgtgaggaggacatcgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtagatggagtgaatactttctcctgtctgtgccaccctggc
tttattggggataagtgtcagacagacatgaatgagtgtctgagtgaaccgtgtaagaat
ggagggacctgctccgactatgtcaacagttacacttgcaagtgccaggcgggatttgat
ggagtccactgtgagaacaacatcgatgagtgcactgagagctcctgtttcaatggtggc
acgtgtgtcgacgggattaactccttctcttgcttgtgccctgtgggcttcactggcccc
ttctgcctccatgagatcaatgaatgcaactctcatccatgcctaaatgaaggagtatgt
gttgatggcctgggtacctaccgctgcacctgccccttgggctacactggcaaaaactgt
cagaccctggtgaacctctgtagtcggtctccatgtaaaaacaaaggtacttgcgttcag
gaaaaagcagagtcccggtgtctgtgtccgtctggatgggctggtgcttactgtgatgtg
cccaatgtatcctgtgaggtggcggctttccacagaggggtgtccattgaccacctgtgc
cagcactctggcatctgcatcaatgctggaaactcgcatcactgccagtgccccctgggc
tacactgggagctactgtgaggagcagctcgatgagtgctcgtccaacccctgccagcac
ggagccacttgcagggacttcatcggcgggtatagatgtgagtgtgtcccaggatatcag
ggtgtcaattgtgagtatgaagtggacgagtgccagaatcagccatgccagaacggaggc
acctgtgtcgaccttgtgaaccatttcaagtgctcctgtccaccaggcactcgaggcctg
ctctgcgaagagaacgttgacgactgtgccggcggtccccactgccttaatggtggtcag
tgtgtggataggattgggggctacagttgccgctgcttgcccggctttgcaggagaacgg
tgtgagggggacatcaatgagtgcctctccaacccctgcagctctgagggcagcctggac
tgcatacagctgaccaacgactacctgtgtgtctgccgcagtgccttcactggtcgtcac
tgtgaaactttcgtcgatgtgtgtccacatatgccttgcctgaatggggggacttgtgct
gtggccagcaacatgcccgatggtttcatttgtcgttgtcccccgggattctccggggca
agatgccagagcagctgtggacaagtgaagtgcaggagaggggagaagtgtgtgcacacg
gcctcaggaccccgctgcttctgccccaacccccaggactgcgagtcaggctgtgccagt
agcccctgccagcatgggggtagctgctaccctcagcgccagcctccttattacttctgc
cagtgttctccaccattctggggcagccactgtgagctttacacggcccccaccagcacc
cctcctgccacctgtctgagccagtattgtgccgacaaagctcgggacggcgtctgcgat
gaggcatgcaacagccatgcctgccagtgggatgggggtgactgttccctgaccatggag
aacccctgggccaactgctcttccccacttccctgctgggattacatcaacaaccagtgt
gatgagctgtgtaacacagccgagtgcctttttgacaactttgaatgccaagggaacagc
aagacgtgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgaccag
ggatgcaacagtgaggagtgtggctgggatgggttggactgtgctgctgaccggccggag
aacctggcggaggggaccctggttatagtggtgctcatgcccccggagcagcttctccag
gatgcccgcagctttttgcgggcactgggcaccctgctccgtaccaacctgcagattaaa
cgggactcccagggggcattcatggtctacccctattatggtgagaagtcggctgccatg
aagaagcagaggatgatacgcaggtcccttcctggtgaccaagaacaggaggtggttggc
tctaaggtgtttctggaaattgacaaccgccaatgtgttcaagattcagaccagtgtttc
aagaacacggatgcagcagcagctcttctggcctctcacgccatccaggggaccttgtcc
taccctcttgtgtccgtcgtcagtgaatctctgactccaaaaggtactcagcttctctat
ctacttgctgttgccgttgtcattatcctgtttattatcttgctgggagttatcatggcg
aaacgaaagcgtaagcatggctccctctggctgcctgaaggtttcacccttcgccgagac
tccagcaatcacaagcgccgtgagccagtgggacaggatgccgtggggctgaaaaatctc
tcagtgcaagtctcagaggctaacctaattggttctggaacaagtgaacattgggttgat
gatgaagggccccagccaaagaaagccaaggctgaagatgaggctttgctctcagaagaa
gatgatgccattgatcgacgtccatggacacagcagcaccttgaggctgcagatatccgc
aggacgccatcgctggcactcactcctccacaggcggagcaggaggtggatgtgttggac
gtgaatgtccgtggcccagatgggtgcaccccactgatgctggcttccctccgaggaggc
agctcagatatgagtgatgaagatgaagatggagaggactcttctgccaacatcatcaca
gacttggtctaccagggtgccagcctgcaggcccagacagaccggactggtgagatggct
ctgcaccttgcagcgcgctactcaagggctgatgctgccaagcgtctcctggatgcaggt
gcagacgccaacgcccaggacaacatgggccgctgccctctccatgctgcagtggcagct
gatgcccagggggtcttccagattctgatccgcaaccgagtaactgatctggacgccagg
atgaacgatggcactacaccactgatcctggccgcccgcctggctgtggagggaatggtg
gcagaactgatcaactgccaagcagatgtgaatgcagtagacgaccatggaaaatccgct
cttcactgggcagctgctgtcaataacgtggaggcaacccttttgctgttgaaaaacggg
gccaaccgagacatgcaagacaacaaggaagagacacctctgtttcttgctgcccgggag
ggaagctatgaagcagccaagatcctgttagaccattttgccaatcgggatatcacagac
cacatggatcgtcttccccgggatgtggctcgggaccgcatgcaccatgacatcgtgcgc
ctcctagacgagtacaatgtgacaccgagccctccaggcactgtgctgacttcggccctc
tcacctgtcatctgtgggcccaacagatctttcctcagcctaaagcacaccccaatgggc
aagaagcctagacggcccaataccaagagtgccatgcccactagcctccctaaccttgcc
aaggaggccaaggatgccaagggtaataggaggaagaagtctctgagtgacaagggtcag
ctgtctgagagttcagtgactttatccccagttgattccttagagtctcctcacacatat
gtttctgacaccacatcctctccaatgattacatcccctggaatcttacaggcctcaccc
aaccctatgttggccactgctgcaccccctgccccagtccatgcacagcatgcactgtct
ttctctaacctgcatgaaatgcagcctttggctcacggggccaaccctgtgcttccctca
gtgagccagctgctatcccaccaccacattgttcccccaggcagtagcagtacggggagc
ttgggtaggctccatccagtcactgttccagcagattggatgaaccgcatggagatgaat
gagacccagtacaatgagatgtttagtatggttctggctccagctgagggcacacaccct
ggcatagctccccagagcagaccacctgaagggaagcatataactacccctcgggagccc
ttgccccccattgtgactttccagctaatccccaaaggcagtatttcccaaccagcaggg
actccccagcctcagtccaactgccccccacctgttacaggccctgtgcccaccatgtac
cagattccagaaatggctcgtttgcctaatatggcttttcccactgccatgatgccccag
caggatgggcaggttgctcagaccattctcccagcctatcatcctttcccagcctctgtg
ggcaagtatcccacaccaccttcacagcatagttatgcttcctcaaatgctgctgagcga
acacccagtcacagtggtcacctccagggtgagcatccctacctgacaccatccccagag
tctcctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgacc
accagccctacccctgggggtgctggaggaggtcaacggggacctggaacacacatgtct
gagccaccgcgcagcaacatgcaggtgtatgcatga
DBGET
integrated database retrieval system
