Panthera pardus (leopard): 109273360
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Entry
109273360 CDS
T06062
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01521
EGFR tyrosine kinase inhibitor resistance
ppad01522
Endocrine resistance
ppad04010
MAPK signaling pathway
ppad04014
Ras signaling pathway
ppad04015
Rap1 signaling pathway
ppad04066
HIF-1 signaling pathway
ppad04068
FoxO signaling pathway
ppad04081
Hormone signaling
ppad04114
Oocyte meiosis
ppad04140
Autophagy - animal
ppad04144
Endocytosis
ppad04150
mTOR signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad04152
AMPK signaling pathway
ppad04211
Longevity regulating pathway
ppad04213
Longevity regulating pathway - multiple species
ppad04510
Focal adhesion
ppad04520
Adherens junction
ppad04550
Signaling pathways regulating pluripotency of stem cells
ppad04730
Long-term depression
ppad04913
Ovarian steroidogenesis
ppad04914
Progesterone-mediated oocyte maturation
ppad05200
Pathways in cancer
ppad05202
Transcriptional misregulation in cancer
ppad05205
Proteoglycans in cancer
ppad05214
Glioma
ppad05215
Prostate cancer
ppad05218
Melanoma
ppad05224
Breast cancer
ppad05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109273360 (IGF1R)
04014 Ras signaling pathway
109273360 (IGF1R)
04015 Rap1 signaling pathway
109273360 (IGF1R)
04066 HIF-1 signaling pathway
109273360 (IGF1R)
04068 FoxO signaling pathway
109273360 (IGF1R)
04151 PI3K-Akt signaling pathway
109273360 (IGF1R)
04152 AMPK signaling pathway
109273360 (IGF1R)
04150 mTOR signaling pathway
109273360 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
109273360 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109273360 (IGF1R)
04140 Autophagy - animal
109273360 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
109273360 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
109273360 (IGF1R)
04520 Adherens junction
109273360 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
109273360 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
109273360 (IGF1R)
04914 Progesterone-mediated oocyte maturation
109273360 (IGF1R)
09156 Nervous system
04730 Long-term depression
109273360 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
109273360 (IGF1R)
04213 Longevity regulating pathway - multiple species
109273360 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109273360 (IGF1R)
05202 Transcriptional misregulation in cancer
109273360 (IGF1R)
05205 Proteoglycans in cancer
109273360 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
109273360 (IGF1R)
05214 Glioma
109273360 (IGF1R)
05218 Melanoma
109273360 (IGF1R)
05215 Prostate cancer
109273360 (IGF1R)
05224 Breast cancer
109273360 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109273360 (IGF1R)
01522 Endocrine resistance
109273360 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109273360 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ppad04090
]
109273360 (IGF1R)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
109273360 (IGF1R)
Protein kinases [BR:
ppad01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
109273360 (IGF1R)
CD molecules [BR:
ppad04090
]
Proteins
109273360 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
109273360
NCBI-ProteinID:
XP_019315685
Ensembl:
ENSPPRG00000007786
UniProt:
A0A9V1G5T4
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTDSNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWGHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNITVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPEDMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgatatccgt
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattacccggggggcc
atcaggattgagaaaaacgctgacctctgttacctctccacggtggactggtccctaatc
ctggatgcggtgtctaataactacatcgtgggaaacaagcccccaaaggaatgcggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaatgaa
tacaactaccgctgctggacgaccaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcttgcacggacagcaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgccggacaacgacacggcctgcgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgagggcttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacgggagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgcgaggaggagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatctg
ctcattaatatccgccgaggcaataacattgcctcggagctggagaacttcatgggactc
atcgaggtggtgacaggctacgtgaagatccgccattcccacgccttggtctccttgtcc
ttcctcaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactctttc
tatgtcctcgacaaccagaacctgcagcagctctgggactggggccatcgcaacctgacc
atcaaagctgggaagatgtactttgctttcaaccccaagttgtgcgtctccgaaatttac
cgcatggaggaggtgaccgggactaaggggcgccagagcaaaggggacatcaatacgagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacgaccacg
tggaagaaccgcatcatcataacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacggagtatgatggc
caggatgcctgtggctccaacagctggaacatggtagatgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcatggactaaagccttggacgcagtatgctgtttac
gtcaaggcggtgaccctcaccatggtggagaatgaccatatccgcggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttcggca
tcaaactcctcttctcagctcatcgtgaagtggaacccgccgtccctgcccaacggcaac
ctgagttactacatcgtgaggtggcagcggcagccccaggacagctacctttaccgccac
aactactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgacgtc
gaggaggttaccgagaaccccaagaccgaagtgtgtggcggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggcggagaaggaggaggctgagtaccgcaaa
gtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacatcacggtggca
gacacctataatatcacagaccccgaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtgatctccaacctccggcctttcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagacgacattcctgggccggtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ctgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgggaatgtgta
tccagacaggagtaccggaagtatggaggcgccaagcttaaccggctcaacccggggaac
tatacggcccggatccaggccacctctctctctggaaatgggtcgtggacggatcccgtg
ttcttctacgtccccgccaaaataacatatgaaaatttcatccacctgatcatcgctctg
cctgttgccgtcctgctgatagtggggggactggttatcatgttgtacgtcttccacaga
aaaagaaataacagcaggctggggaatggagtgctgtatgcttcggtgaacccagagtac
ttcagtgccgcagatgtgtatgtacctgatgagtgggaggttgctcgggagaaaatcacc
atgagccgagagctggggcagggctcgtttgggatggtctacgaaggagttgccaaaggc
gtggttaaagatgagcccgaaaccagggtggccatcaaaacggtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacgcggggcgatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcccggaac
tgcatggtggctgaagatttcacggtcaaaatcggagatttcggtatgacgagagatatc
tacgagacagactattaccggaaaggagggaaggggctgctgcctgtgcgctggatgtca
cccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttcggggtc
gttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggaacccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggatctggagccggaggacatg
gagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccccggcgtgctggttctccgagccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
