KEGG   Panthera pardus (leopard): 109277026
Entry
109277026         CDS       T06062                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04010  MAPK signaling pathway
ppad04015  Rap1 signaling pathway
ppad04218  Cellular senescence
ppad04380  Osteoclast differentiation
ppad04620  Toll-like receptor signaling pathway
ppad04664  Fc epsilon RI signaling pathway
ppad04668  TNF signaling pathway
ppad04750  Inflammatory mediator regulation of TRP channels
ppad04912  GnRH signaling pathway
ppad04935  Growth hormone synthesis, secretion and action
ppad04936  Alcoholic liver disease
ppad05014  Amyotrophic lateral sclerosis
ppad05022  Pathways of neurodegeneration - multiple diseases
ppad05132  Salmonella infection
ppad05135  Yersinia infection
ppad05145  Toxoplasmosis
ppad05161  Hepatitis B
ppad05163  Human cytomegalovirus infection
ppad05167  Kaposi sarcoma-associated herpesvirus infection
ppad05169  Epstein-Barr virus infection
ppad05170  Human immunodeficiency virus 1 infection
ppad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppad05417  Lipid and atherosclerosis
ppad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109277026 (MAP2K6)
   04015 Rap1 signaling pathway
    109277026 (MAP2K6)
   04668 TNF signaling pathway
    109277026 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    109277026 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109277026 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    109277026 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109277026 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    109277026 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109277026 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109277026 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109277026 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109277026 (MAP2K6)
   05161 Hepatitis B
    109277026 (MAP2K6)
   05163 Human cytomegalovirus infection
    109277026 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109277026 (MAP2K6)
   05169 Epstein-Barr virus infection
    109277026 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109277026 (MAP2K6)
   05135 Yersinia infection
    109277026 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109277026 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    109277026 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    109277026 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109277026 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    109277026 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109277026 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109277026 (MAP2K6)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     109277026 (MAP2K6)
Protein kinases [BR:ppad01001]
 Serine/threonine kinases: STE group
  STE7 family
   109277026 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 109277026
NCBI-ProteinID: XP_019321952
Ensembl: ENSPPRG00000024660
UniProt: A0A9V1GGQ9
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPGDKFTEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagacttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgatctggaaccaataatggaactgggg
cgaggtgcgtacggggtcgtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtcctttcacagtcaccttttatggtgcactcttc
cgggagggtgatgtttggatttgcatggaactcatggatacgtcgctagataaattctac
aaacaagtgattgacaaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaggcgttagaacatttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgtcgctaaaactattgatgcaggatgcaaaccctacatg
gcccccgaaagaataaacccagagctcaatcagaagggatatagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcgatccttcggtttccctatgactcttgg
ggaactcccttccaacagctcaaacaggtggtagaggagccctcaccacagctcccggga
gacaagttcaccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaattgattcttggagactaa

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