Panthera pardus (leopard): 109277087
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Entry
109277087 CDS
T06062
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04140
Autophagy - animal
ppad04141
Protein processing in endoplasmic reticulum
ppad04210
Apoptosis
ppad04932
Non-alcoholic fatty liver disease
ppad05010
Alzheimer disease
ppad05012
Parkinson disease
ppad05014
Amyotrophic lateral sclerosis
ppad05016
Huntington disease
ppad05017
Spinocerebellar ataxia
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
109277087 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109277087 (ERN1)
09143 Cell growth and death
04210 Apoptosis
109277087 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109277087 (ERN1)
05012 Parkinson disease
109277087 (ERN1)
05014 Amyotrophic lateral sclerosis
109277087 (ERN1)
05016 Huntington disease
109277087 (ERN1)
05017 Spinocerebellar ataxia
109277087 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
109277087 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109277087 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109277087 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109277087 (ERN1)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109277087 (ERN1)
Protein kinases [BR:
ppad01001
]
Serine/threonine kinases: Other
IRE family
109277087 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
109277087
NCBI-ProteinID:
XP_019322082
Ensembl:
ENSPPRG00000009424
LinkDB
All DBs
Position
Unknown
AA seq
973 aa
AA seq
DB search
MCLGCGLSNLSVFICEIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEV
EEKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
RAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDSPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYCHE
SPELRPPVTPDAL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgtgccttggatgcgggctctctaacctcagcgtcttcatctgtgagatttttggaagt
cccagcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttg
catgctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctg
caggttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctg
tatacacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagag
ctcgtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtataca
atcaccatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactac
gcggcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccctgtggtggccttttatgtctggcagcgggagggtctgcggaaggtgatgcac
atcaacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgag
ggggtcgccgttgtgccccggggcagcacacttcctttgctggaaggcccccagactgac
ggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagttt
gaccctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataat
ctgcccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggtcgagcagacttcagaaaatgcgcccaccgccgtttcacaggaggtg
gaggagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaag
gacatagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaa
ctagagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacgtg
gctcaggatgctgagctcctggactcgtccggcctgtactcagagagctcgggcaccagc
agccccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctcc
agggctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtg
attgttgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacg
attgtgtaccggggcatgttcgacaaccgcgatgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaac
gtgattcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggagcagaaggacttcgcccacctcggcctggag
cccatcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctgtccatgcccaacgcacatggcagg
atcaaggccatgatctctgacttcggcctctgcaagaagctggctgtgggcaggcacagt
ttcagccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagc
gaggactgtaaggacaatcccacctacacagtggacatcttctctgcgggctgtgtcttt
tactacgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggcgcctacagcctcgactgcttacacccggagaagcatgaagacgtcatt
gcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaag
catgtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggac
gtgagtgaccgaatagaaaaggaatccctggacagcccgatagtgaagcagctggagcga
ggcgggagagccgtggtaaagacggactggagagagaacatcaccgtccccctgcagaca
gatctgcgtaaattcagaacctataaaggtggctctgtccgcgaccttctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctct
ctccccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacc
taccgggccatggagccctgcagccacgagaggctcttccagccttactactgccacgag
tccccagagctccggccccccgtgactccagacgccctttga
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integrated database retrieval system
