Panthera pardus (leopard): 109277571
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Entry
109277571 CDS
T06062
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00220
Arginine biosynthesis
ppad00330
Arginine and proline metabolism
ppad01100
Metabolic pathways
ppad04020
Calcium signaling pathway
ppad04081
Hormone signaling
ppad04145
Phagosome
ppad04371
Apelin signaling pathway
ppad04713
Circadian entrainment
ppad04730
Long-term depression
ppad04926
Relaxin signaling pathway
ppad04970
Salivary secretion
ppad05010
Alzheimer disease
ppad05014
Amyotrophic lateral sclerosis
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05410
Hypertrophic cardiomyopathy
ppad05412
Arrhythmogenic right ventricular cardiomyopathy
ppad05414
Dilated cardiomyopathy
ppad05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
109277571 (NOS1)
00330 Arginine and proline metabolism
109277571 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
109277571 (NOS1)
04020 Calcium signaling pathway
109277571 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
109277571 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
109277571 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
109277571 (NOS1)
09154 Digestive system
04970 Salivary secretion
109277571 (NOS1)
09156 Nervous system
04730 Long-term depression
109277571 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
109277571 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109277571 (NOS1)
05014 Amyotrophic lateral sclerosis
109277571 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
109277571 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
109277571 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
109277571 (NOS1)
05414 Dilated cardiomyopathy
109277571 (NOS1)
05416 Viral myocarditis
109277571 (NOS1)
Enzymes [BR:
ppad01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
109277571 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
109277571
NCBI-ProteinID:
XP_019322874
Ensembl:
ENSPPRG00000012064
UniProt:
A0A9V1GI53
LinkDB
All DBs
Position
Unknown
AA seq
1463 aa
AA seq
DB search
MENQVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLAAPTTAVDLSHQSSASREHSPAVDRATGPGNGPQHAQDGGQEAGSLPHTKSRAP
GPPGQDSAKKSIQGSQNSDLLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVDRGMD
GKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRF
LKVKNWETDVVLTDTLHLKSTLEMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFPLAKE
FIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCVGRIQ
WSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI
RYAGYKQPDGSILGDPANVEFTEICVQQGWKPPRGRFDILPLLLQANGNDPELFQIPPEL
VLEVPIRHPRFEWFKDLGLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDYCD
NSRYNILEEVAKNMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK
HMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPEPWNTHVWKGTN
GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA
FDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKY
PEPLRFFPRKGPPLPQGDTEVHGLAAARDSQQRSYKVRFNSVSSYSDSHKSSGDGPDLRD
NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEA
FRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSN
VHRKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNREDLVNA
LMERLEDAPPVNQLVKVELLVERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITTPPTP
LQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPTTLLLTQ
LSLLQPRYYSISSSPDMYPDEVHLTVAVVSYHTRDGEGPIHHGVCSSWLNRIPADEVVPC
FVRGAPSFHLPRNPQVPCILIGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQS
KIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEHLAEPVYRALKEQGGHI
YVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTN
RLRSESIAFIEESKKDTDEVFSS
NT seq
4392 nt
NT seq
+upstream
nt +downstream
nt
atggagaatcaggtgttcagcgttcagcagatccaacccaacgtcatctctgtccgcctc
ttcaagcgcaaggtggggggcctggggttcctggtgaaagagcgggtgagcaagccgccc
gtgatcatctccgacctgattcgggggggtgccgcggagcagagcggcctcatccaggcc
ggtgacatcatccttgcagtcaacggccagcccctggtggacctgagctatgacagcgcc
ctggaggtgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggcccc
gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaagaccatc
cgcgtgacacggcctctggctgcccccaccaccgctgtcgatctgtctcaccagtcatcg
gccagcagagagcactcaccggcagtggacagggccacgggtcctggcaatgggccgcag
cacgcccaagacggtgggcaggaagccggctctctcccccataccaagagccgggctccc
gggcccccgggccaggactctgccaagaagagcatccagggcagccagaacagtgatttg
ctcaaagagatagaacctgtactgagccttctcaccagtgggagcaaagggatcaatggc
gggggaccttccaaggcagagacgaaggatgcagaagtccaggtggacagaggtatggat
ggcaagtcacacaagccactgcccctgggcgtggagaatgaccgagtcttcagtgacctg
tgggggaagggccacgtgcctgtcgtcctcaacaacccgtattcagagaaggagcagccc
cctgcctcgggaaaacagtctcctacaaagaacggcagcccctccaagtgcccccgcttc
ctcaaggtcaagaactgggagaccgacgtggtcctcactgacacccttcaccttaagagc
acactggaaatgggctgcaccgagcacatctgtatgggctccatcatgctcccctctcag
cagatacgaaggcctgaagacgtccgcacaaaagaacagctcttccctctcgccaaagag
ttcattgaccagtactactcatcaattaaaaggtttggctccaaagcccacacggagagg
ctggaagaggtgaacaaagagatcgaaaccaccggcacctaccagctcaaagacacggag
ctcatctacggggccaagcatgcctggcggaacgcctcccgctgcgtgggcaggatccag
tggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcacgggatgttcaac
tacatctgcaaccacatcaagtatgccaccaacaaagggaacctcagatccgccatcacc
atattcccccagaggacggacggcaagcacgatttccgagtctggaactctcagctcatc
cgctatgccggctacaagcagcctgatggctccatcctgggggacccagccaatgtggaa
ttcacagagatctgtgtgcagcagggctggaaacccccaagaggccgcttcgatatcctg
ccactcctgctccaggccaacggcaacgatcccgagctcttccagatccccccagagctg
gtgttggaagtgcccatcaggcaccccaggtttgagtggttcaaggatctgggcctgaag
tggtatggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcacc
gcctgtcccttcagcggctggtacatgggcacagagattggcgtccgcgactattgtgac
aactctcgatacaacatcctggaggaagtggccaagaacatgaacttggacatgaggaag
acgtcctccctgtggaaggaccaagcactggtggaaatcaacattgctgttctctacagc
ttccagagtgacaaagtgaccatcgttgaccaccactctgccaccgagtccttcatcaag
cacatggagaatgaataccgctgccgggggggctgccccgccgactgggtgtggattgtg
ccccccatgtctggcagtgtcacccctgtcttccaccaggagatgctcaactaccgactc
accccgtccttcgaataccagcctgagccttggaacacccacgtctggaaaggcaccaat
ggaacccccacaaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttc
tcagccaagcttatggggcaggcaatggccaagagggtcaaggcgaccatcctttatgcc
acagagacgggcaagtcgcaggcctatgctaaaaccttgtgtgagatcttcaaacatgcc
tttgatgccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaaact
ctggtcctagtggttaccagcacttttggcaatggtgaccccccagagaatggggagaaa
ttcggctgtgctttgatggaaatgaggcaccccaactccgtgcaggaggaaaggaagtac
ccggaacccttgcgtttctttccccgtaaagggcctcccctcccccaaggtgacacagaa
gtccatggtctggctgcagcccgtgacagccagcagaggagctacaaggtccgattcaat
agtgtttcctcgtattctgactcccataaatcatcaggagacgggccagacctcagagac
aactttgagagtgctggacccctggccaacgtgaggttctccgtatttggccttggctcc
cgggcttaccctcatttctgcgcctttggacatgccgtggacaccctcctggaggagctg
ggaggagagaggatcctgaagatgagggagggagacgagctctgtgggcaggaagaggct
ttcaggacctgggccaagaaggtcttcaaggcagcctgcgatgtgttctgcgtgggagat
gacgtcaacattgagaaggcaaacaactccctcatcagcaacgaccgcagctggaagaga
aacaagttccgcctcacctacgtggccgaagctccggaacttacacaaggtctatccaat
gtccacagaaagcgggtctcggccgctcgactcctcagccgccaaaaccttcagagccct
aaatccagccgatcaacgatcttcgtgcgtctccacaccaatgggaatcaggagctgcag
taccagcctggggaccacctgggcgtcttccctggcaaccgcgaggacctcgtgaacgcc
ctgatggagcggctggaagatgctcccccagtcaaccagctggtgaaggtggaacttctc
gtggagcggaacacggctttgggcgtcatcagtaactggacagatgagcaccgcctcccg
ccctgcaccatcttccaggccttcaagtactacctggacatcaccacgccgcccacgcca
ctgcagctgcagcagtttgcgtccctggccaccagcgagaaagagaagcagcgactcttg
gtcctcagcaagggcttgcaggagtacgaggaatggaaatggggcaagaaccccaccatc
gtggaggtgctggaagagttcccgtccatccagatgcccaccaccctgctcctgacccag
ctgtccctgctgcagcctcgatactattcaatcagttcttccccagacatgtaccctgac
gaggtgcacctcaccgtggccgttgtctcctaccacacccgagatggagaaggaccaatt
caccacggcgtgtgctcctcctggctcaaccggataccggctgacgaagtggtcccctgt
ttcgtgagaggagcacccagcttccacctgccccgaaatccccaagtgccctgtatcctc
attggcccaggcactggcattgcccctttccgaagcttctggcagcagcgacaatttgat
atccagcacaaaggaatgagcccctgccccatggtcctggtgtttgggtgccggcaatcc
aagatagaccacatctacagggaggaaactctacaggccaagaacaagggggtcttcaga
gaactctacacggcctactcgcgggagccagacaaaccaaagaagtacgttcaggacatc
ctgcaggagcacttggcagaacctgtgtaccgagccctgaaggagcaagggggccacatt
tacgtctgcggggacgtcaccatggccgccgatgtcctcaaagccatccagcgcatcatg
acccagcaagggaaactctcagcggaggatgccggcgtgttcatcagcaggctgagggat
gacaaccggtaccatgaggatattttcggggtcaccctgcgaacatatgaagtgaccaac
cgccttagatctgaatccattgccttcattgaggagagcaaaaaagacactgatgaagtt
ttcagctcctaa
DBGET
integrated database retrieval system
