Panthera pardus (leopard): 109278247 Help Entry 109278247         CDS       T06062                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism ppad  Panthera pardus (leopard) Pathway ppad00230   Purine metabolism ppad01100   Metabolic pathways ppad01522   Endocrine resistance ppad04015   Rap1 signaling pathway ppad04020   Calcium signaling pathway ppad04022   cGMP-PKG signaling pathway ppad04024   cAMP signaling pathway ppad04062   Chemokine signaling pathway ppad04072   Phospholipase D signaling pathway ppad04081   Hormone signaling ppad04082   Neuroactive ligand signaling ppad04114   Oocyte meiosis ppad04211   Longevity regulating pathway ppad04213   Longevity regulating pathway - multiple species ppad04261   Adrenergic signaling in cardiomyocytes ppad04270   Vascular smooth muscle contraction ppad04371   Apelin signaling pathway ppad04540   Gap junction ppad04611   Platelet activation ppad04713   Circadian entrainment ppad04714   Thermogenesis ppad04723   Retrograde endocannabinoid signaling ppad04724   Glutamatergic synapse ppad04725   Cholinergic synapse ppad04727   GABAergic synapse ppad04750   Inflammatory mediator regulation of TRP channels ppad04911   Insulin secretion ppad04912   GnRH signaling pathway ppad04913   Ovarian steroidogenesis ppad04914   Progesterone-mediated oocyte maturation ppad04915   Estrogen signaling pathway ppad04916   Melanogenesis ppad04918   Thyroid hormone synthesis ppad04921   Oxytocin signaling pathway ppad04923   Regulation of lipolysis in adipocytes ppad04925   Aldosterone synthesis and secretion ppad04926   Relaxin signaling pathway ppad04927   Cortisol synthesis and secretion ppad04928   Parathyroid hormone synthesis, secretion and action ppad04934   Cushing syndrome ppad04935   Growth hormone synthesis, secretion and action ppad04961   Endocrine and other factor-regulated calcium reabsorption ppad04962   Vasopressin-regulated water reabsorption ppad04970   Salivary secretion ppad04971   Gastric acid secretion ppad04972   Pancreatic secretion ppad04976   Bile secretion ppad05032   Morphine addiction ppad05163   Human cytomegalovirus infection ppad05166   Human T-cell leukemia virus 1 infection ppad05200   Pathways in cancer ppad05207   Chemical carcinogenesis - receptor activation ppad05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109278247 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109278247 (ADCY9)    04371 Apelin signaling pathway     109278247 (ADCY9)    04020 Calcium signaling pathway     109278247 (ADCY9)    04072 Phospholipase D signaling pathway     109278247 (ADCY9)    04024 cAMP signaling pathway     109278247 (ADCY9)    04022 cGMP-PKG signaling pathway     109278247 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     109278247 (ADCY9)    04081 Hormone signaling     109278247 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109278247 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     109278247 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109278247 (ADCY9)    04062 Chemokine signaling pathway     109278247 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     109278247 (ADCY9)    04923 Regulation of lipolysis in adipocytes     109278247 (ADCY9)    04912 GnRH signaling pathway     109278247 (ADCY9)    04913 Ovarian steroidogenesis     109278247 (ADCY9)    04915 Estrogen signaling pathway     109278247 (ADCY9)    04914 Progesterone-mediated oocyte maturation     109278247 (ADCY9)    04921 Oxytocin signaling pathway     109278247 (ADCY9)    04926 Relaxin signaling pathway     109278247 (ADCY9)    04935 Growth hormone synthesis, secretion and action     109278247 (ADCY9)    04918 Thyroid hormone synthesis     109278247 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     109278247 (ADCY9)    04916 Melanogenesis     109278247 (ADCY9)    04925 Aldosterone synthesis and secretion     109278247 (ADCY9)    04927 Cortisol synthesis and secretion     109278247 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109278247 (ADCY9)    04270 Vascular smooth muscle contraction     109278247 (ADCY9)   09154 Digestive system    04970 Salivary secretion     109278247 (ADCY9)    04971 Gastric acid secretion     109278247 (ADCY9)    04972 Pancreatic secretion     109278247 (ADCY9)    04976 Bile secretion     109278247 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     109278247 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     109278247 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     109278247 (ADCY9)    04727 GABAergic synapse     109278247 (ADCY9)    04725 Cholinergic synapse     109278247 (ADCY9)    04723 Retrograde endocannabinoid signaling     109278247 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109278247 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     109278247 (ADCY9)    04213 Longevity regulating pathway - multiple species     109278247 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     109278247 (ADCY9)    04714 Thermogenesis     109278247 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109278247 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     109278247 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109278247 (ADCY9)    05163 Human cytomegalovirus infection     109278247 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     109278247 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109278247 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109278247 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109278247 (ADCY9) Enzymes [BR:ppad01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109278247 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom Motif Other DBs NCBI-GeneID:  109278247 NCBI-ProteinID:  XP_019323964 Ensembl:  ENSPPRG00000010573 LinkDB All DBs Position Unknown AA seq 1352 aa AA seqDB search MASPPHQQLLRHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS AGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTRRRFRYAL FYIGFACLLWSIYFGVHMRSRLIVMVAPALCFLVVCGGFFLFTFTKVYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTLATKPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLCLGVAYSVLFETFGYHFRDKDCFPPPEAGAPHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIDEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGRVTERLGQSVVADQLKGLKTYLIAGQRAKESRCSCSEALLSGYEVIDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQEEHKN STKAPGAPNSKTQNGLLSPPHEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAASMPPPPAALAVFGAALLLEVLSLVVSVR MVFFLEDVMACTKRLLERIAGWLPRHFIGAILVSLPALAVYSHITSEFDTDIHFTVFAGS AILTAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYISLCPDSSVVISHLDVGQNFSSKG NPCNSSLPHDGRAASLIGQEGVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKI QSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKEC YRVLNELIGDFDELLSRPGYGSIEKIKTIGATYMAASGLNGAQCRDGSHPQEHLQVLFEF AKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDSTG VECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDSGAVPQHQLSISPD IRVQVDGSIGRSPTDEIANLVPSVQSADKTPPGSENNVQARDAHLSSKRPWKEPVKAEER CRFGKAIEKSDCEDADAEEASELTRLNVSESV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcggcaccacagcacggaggtgagctgtgac tccagcggagacagcaacagcgtgagggtcaaaatcaaccccaagcagctgtcctccaac agccaccccaagcactgcaagtacagcatctcctccagctgtagcagctctggggactcg gcaggcgtcccccggagagtgggcgctggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagccggtggtgggaccccaagttcgactcggtgaacctg gaggaggcttgcatggagcgctgcttcccgcagacccggcgccgcttccggtatgcgctc ttctacatcggcttcgcctgccttctgtggagcatctattttggggtccacatgcggtcc cgcctgattgtcatggtagcccctgctctgtgcttcctcgtcgtgtgtgggggctttttt ctgtttaccttcaccaaggtgtatgcccggcattacgtgtggacctccctggttctcacc ctcctggtgtttgccctgaccctggctgcccagtttcaggttctgacgcctctctcagga cgtgttgacagctccaatcacaccctcgccaccaagcccacggacacttgtttgtctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgtgtttgggagtggcctattctgttctctttgagacctttggc tatcacttccgagacaaagactgctttcccccacccgaagcaggggccccacactgggag ctgctgagcagagccctgctccacgtctgcattcacgccattgggatccacctcttcatc atgtcccaggtgagatccaggagcacctttctcaaggtgggacagtcaattatgcacgga aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaaacagggggatgaggagagcgagaattctgtcaaaagg cacgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctata gcgttccgcccttttaaaatgcagcagatcgatgaagtcagtattttatttgcagatatc gtgggcttcaccaagatgagtgccaataagtccgctcacgccctggtgggtctcctcaac gatctgttcggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaatcagcacc ctgggagactgctactattgcgtggcagggtgtccagagccccgggctgaccatgcctac tgctgcattgagatgggcttgggcatgatcagagccatcgagcagttctgccaggagaag aaagagatggtgaacatgcgtgtcggggttcacacggggaccgtcttgtgtggcattttg ggcatgaggaggttcaaattcgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagttgccggcaaggttcacatttctgaggccactgcaaaatacctagat gatcggtacgaaatggaagacgggagggtgactgaacggctcggccagagcgttgttgct gatcagctgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcgt tgcagctgttcagaggccttgctttctggctatgaggtcattgacggctcacgggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcgtgcggaatcacgttcgcccccaaa tcggaagctggtgcggaaggaggagcggtccaaaacggctgtcaagaggagcataaaaac agcaccaaggctcctggagctcctaattccaaaactcaaaatggacttctgagtcctccc catgaggagaagctcaccaacagtcagacctccctgtgtgagatcttacaggaaaaggga aggtgggcaggagtgagcttggaccagtcagctctccttccgctgagattcaagaacatc cgggagaaaacagacgcccattttgttgatgttatcaaagaagacagcctgatgaaggat tattttttcaagccacccatcaatcagttcagcttgaacttcctggatcaggagctagag cgatcctatcggaccagctatcaagaagaggttataaagaattctcccgtgaagactttt gccagcgccaccttcagctccctcctggatgtgtttctgtcgacgacagtgtttctgatt ctgtccatcacctgcttcctgaagtacggggctgcctccatgcctcccccgcccgccgcc ctggctgtcttcggtgccgccctgctgctggaggtgctgtccctcgtggtctccgtcagg atggtgtttttcctggaggatgtgatggcttgtaccaagcgcctgctggagcggatagcc ggctggctcccgcgccatttcattggggccatcctggtgtcactccctgctctcgctgtc tattcacatatcacctctgaatttgacaccgacatacacttcaccgtgtttgcgggctcc gccatcctgaccgctgtcgtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttagccaccgtcgtcggggctgggccgctgctcctgctctacatctccctttgc ccggacagttccgtagtaatttcacacctggatgtgggacagaatttcagttccaagggg aatccgtgcaacagttccttgccgcatgacggcagagcagccagcctgattggccaggag ggggttcttgtcttctttctcctgctcttgttggtctggttcctgaatcgagaattcgag gtcagctaccgcctgcactaccacggggatgtggaggcggacctccaccgcaccaagatc cagagcatgagggaccaagctgactggctgctgagaaacatcatcccctaccacgtggct gagcagctgaaggtctcccagacctactccaagaaccacgacagcgggggcgtcatcttt gccagcatcgtcaacttcagcgagttctacgaggagaactacgaggggggcaaggagtgc taccgcgtcctcaacgagctcatcggggacttcgacgagctcctgagcaggccgggctac ggcagcatcgagaagatcaagaccatcggagccacgtacatggctgcgtcagggctgaac ggcgcgcagtgccgggacggcagccacccgcaggagcacctgcaggtcctgtttgagttc gccaaggagatgatgcgcgtggtggacgacttcaacagcaacatgctgtggttcaacttc aagctcagggtgggcttcaaccacgggccgctcacggcgggggtcatcggcaccaccaag ctgctctatgacatctggggcgacaccgtcaacatcgccagcaggatggacagcacgggg gtggagtgccggatccaggtgagcgaggagagctaccgcgtcctgagcaagatgggctat gacttcgactaccgagggacggtgaacgtcaagggcaagggccagatgaagacctacctg tacccaaagtgcacggacagcggggccgtgccgcagcaccagctgtccatctccccggac atccgagtccaggtggacggcagcatcgggcggtctcccacggacgagatcgccaacctg gtgccttctgtccagagtgcggacaagacgcctccgggttccgaaaacaacgtgcaggcc agggatgctcacctgtcctctaagaggccctggaaggagcctgtcaaagccgaagaaagg tgtcgatttggcaaagccatagagaaaagcgactgtgaagacgcggacgctgaagaagcc agtgagctcaccaggctcaacgtttctgagagcgtgtga

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