Panthera pardus (leopard): 109278500
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Entry
109278500 CDS
T06062
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04270
Vascular smooth muscle contraction
ppad04360
Axon guidance
ppad04611
Platelet activation
ppad04625
C-type lectin receptor signaling pathway
ppad04810
Regulation of actin cytoskeleton
ppad05135
Yersinia infection
ppad05152
Tuberculosis
ppad05163
Human cytomegalovirus infection
ppad05200
Pathways in cancer
ppad05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
109278500 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109278500 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
109278500 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
109278500 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
109278500 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109278500 (ARHGEF12)
05205 Proteoglycans in cancer
109278500 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
109278500 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
109278500 (ARHGEF12)
05152 Tuberculosis
109278500 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ppad04131
]
109278500 (ARHGEF12)
Membrane trafficking [BR:
ppad04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
109278500 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
COS
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
109278500
NCBI-ProteinID:
XP_019324402
Ensembl:
ENSPPRG00000004218
UniProt:
A0A9V1GKX4
LinkDB
All DBs
Position
Unknown
AA seq
1543 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVESSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTSSRSLGDPPTVSEVEADPGDGLGRIDYSSGDAS
RPSSDSAESPKSALKERIYLEENPEKSEVIQDTDTQSLIGSPSPRMAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISIDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDSAKLRQSGLAGEGTDVGY
LPANSMSSGASGATLSQEGGKENDLGSKQVGETPASGDCMDGAPRTPNTIFDFPPPPLDQ
VQEEEWEVERVPEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAK
PIPLPQSPPCEGDNDEEEPPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQSHSLGAS
GKSEVDDLFVAERQFAKERHADGTLQEAGASYQIPIPDPHLPASEERWALDALRNLGLLK
QLLVQQLGLAEKSTQEDWSRFPRYRTASSGVQTDSVTQNSENSKACPPGEGQVSCRTESG
DISTCYSPRTSTESSAPRDSVVLAFQDSQASNILVMDHMIMTPEMPPAEPEGSLDESGEH
FFDAREAHSDDNPSEGDGVVKKEEDVNLRISGNYLILDGYDAVQESSTDEEVASSLPPPP
TTGAPPTDSAGQQQHSPQNAHSDGALSPFTPEFLVQQRWGAMEDSCFEIQSPPCCADSQS
QIVEYIRKIEADLEHLKKVEESYNILCQRLAGSALTDKHSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcacacagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgatcccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcagcgttgtgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggtaca
ttggtgactcattcaaaccatttggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgccgattctgaa
gtagagtcatcagtcattggacatatgtctcccatcatgacatcccctcattcacctgga
gcatctgggaacatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaagaacggctg
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttacgtcctccaggtctttaggtgaccccccgacagtcagtgag
gtagaagcagaccctggtgatggactagggagaattgactacagcagcggagatgcttct
cggcccagtagtgacagcgcagaaagtcccaagagtgccctgaaagagaggatttatcta
gaggaaaacccagagaaaagcgaagtgattcaggacactgacactcagtcactcatcggg
agcccctctccccgaatggcacctcatattattggagcagaggatgatgattttggtact
gaacatgaacagatcaatgggcagtgcagctgtttccagagcattgaactgctaaaatct
cgccctgctcacctggctgttttcttacaccacgtagtttcacagtttgaccctgcaacg
ttgctctgttatctctattcagacctatataagcagaccaattccaaggagactcggcgt
gtcttcctcgagtttcatcagtttttcctggatcgatctgcacacctgaaagtttctgtt
cctgatgaaatatcaatagatctagaaaaaagaagacctgagcttatacctgaggatcta
caccgccactatattcaaactatgcaggaaagagtccacccagaagttcagaggcacttg
gaagattttcggcagaaacgtagcatggggctgaccttggctgaaagcgagctgacaaaa
ctcgatgcggagcgagacaaggaccgggtaactttggagaaggaacgggcatgtgcggaa
cagattgttgccaaaatcgaagaagtgttgatgactgctcaggctgtagaagaagataaa
agttcaacaatgcagtatgttatccttatgtacatgaagcatttgggagtaaaagtgaaa
gagcctcgaaatttggagcacaagcgaggtcggattggattccttccaaaaatcaagcaa
agtatgaagaaagatcgagaaggcgaagaaaaagggaagcgcagaggattccccagcatc
ctgggacccccaaggagaccaagccgtcatgacaacagtgcaattggcagagctatggaa
ctacagaagcagcggcaccctaagcacttatccacaccctcttctgtgagtcctgagcct
caggactctgccaagttgcgccagagtgggttagcaggtgaaggaacagacgttgggtac
ctgccagccaattccatgtcctctggggcttcaggggccactctttcccaggaaggaggg
aaagagaatgatctgggatcaaagcaagttggagaaacacctgcatctggagactgcatg
gatggcgcccctcgcactcccaataccatcttcgatttcccacctcctcccttagaccaa
gtgcaggaggaggagtgggaggtggaaagggtgcctgaacatgggacaccaaagcccttt
cgaaaattcgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagatccacccaactggcaacagctcgttagtcgagaagtgttactggga
ctaaagccttgtgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaggttcttgatcaagtgttctaccagcgagtatccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttggaagatattcttcaa
cttcacattggattgaatgagcaaatgaaggctgttcgaaagaggaatgagacctcagtt
attgatcagattggggaagatttactgacctggttcagcggaccaggggaggagaagttg
aaacacgctgctgccaccttttgcagtaaccaaccttttgccctggaaatgatcaagtct
cgtcagaaaaaggattcccgatttcagacttttgtgcaagatgccgagagcaatccgctg
tgtcgtcgtctgcagctgaaggatatcattcctacccaaatgcagaggcttactaagtac
cctcttctgttagataatattgccaaatacacagaatggccaatggaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaactatgtaaatcaggctgtcaaggag
gcagaaaataagcagcgcctagaagactatcagcgtcgcctcgatacctccaatctgaag
ttgtcagagtacccaaatgtggaagagctcaggaatttggatttaacaaaaaggaagatg
attcacgaagggccactggtctggaaggtgaatcgggataaaactatcgatctgtacacg
ttgctgctggaagacattcttgtattgttacaaaaacaggatgacagactggtgttacga
tgtcatagtaagattctggcatccacagctgatagcaaacacacgtttagccctgtcatt
aagttgaatacagtgttggttcgacaagtggcaacagataacaaagctttgtttgtcatc
tccatgtcggacaatggggcccaaatttatgaactggtggcacagacagtttctgaaaag
actgtctggcaggaccttatctgccggatggccgcatcagtgaaggaacagtcggcgaag
ccgatcccactgccccagtcaccaccttgcgaaggagacaacgatgaagaagaacctcca
aaattaaaagtggagcatcatagcatttcagtccctggtctgcagagtccagacagagat
ttgggattagagtctcccttgatatcgtcaaaacctcagtctcattcactgggtgcctct
gggaagtccgaggtagatgatctgtttgtggctgagagacagtttgctaaggagcggcat
gcagatgggactctgcaggaagctggagcaagttaccaaatcccaatcccagacccgcac
ttgcctgcctcagaagaacggtgggccttggacgcactaaggaatttgggcttgttgaag
cagttgcttgtacaacagctgggtttggctgagaagagcactcaggaagactggtcacgt
ttcccgagatacaggacagcgtcttccggggtgcagacagacagtgtaacccagaactct
gaaaatagtaaggcctgtcctcctggtgaaggacaggtgtcctgtagaactgaaagtggt
gacatttccacttgttacagtccacggacttcaactgaatcttctgctccacgagattca
gtggtactggcattccaagatagccaggcaagtaacattttagtaatggaccacatgatt
atgaccccagagatgcctcctgcagagccagaagggagtcttgatgagagtggagagcac
ttttttgatgcccgggaagcacatagtgatgataatccatcagaaggtgatggagtggtt
aagaaggaagaggatgttaatttgcgcatctcaggaaactatttgatccttgacggctac
gatgcggtgcaggagagctccacggatgaggaggttgcttcctcactccccccaccgccc
acgacaggcgccccccccacggactctgccggccagcagcagcattctccccagaacgcc
cattccgatggggcgctctcaccgttcaccccggaattcctggtccagcagcgctgggga
gctatggaggattcctgttttgagatccagagtcccccctgttgtgcagactcacaaagc
cagatcgtggagtacattcgtaagatcgaggctgaccttgaacacttaaagaaggtggag
gaaagttacaacattctttgccaaaggctggctggatcagccctcacagacaagcactca
gataaaagttag
DBGET
integrated database retrieval system
