Panthera pardus (leopard): 109278955
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Entry
109278955 CDS
T06062
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01521
EGFR tyrosine kinase inhibitor resistance
ppad04010
MAPK signaling pathway
ppad04014
Ras signaling pathway
ppad04015
Rap1 signaling pathway
ppad04020
Calcium signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad04370
VEGF signaling pathway
ppad04510
Focal adhesion
ppad05205
Proteoglycans in cancer
ppad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109278955 (KDR)
04014 Ras signaling pathway
109278955 (KDR)
04015 Rap1 signaling pathway
109278955 (KDR)
04370 VEGF signaling pathway
109278955 (KDR)
04020 Calcium signaling pathway
109278955 (KDR)
04151 PI3K-Akt signaling pathway
109278955 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109278955 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
109278955 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
109278955 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109278955 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109278955 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ppad04090
]
109278955 (KDR)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
109278955 (KDR)
Protein kinases [BR:
ppad01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
109278955 (KDR)
CD molecules [BR:
ppad04090
]
Proteins
109278955 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
C2-set_2
Ig_4
BppU_N
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
109278955
NCBI-ProteinID:
XP_019325208
Ensembl:
ENSPPRG00000005424
UniProt:
A0A9V1GM46
LinkDB
All DBs
Position
Unknown
AA seq
1356 aa
AA seq
DB search
MESKALLAVVLWFCVETRAASVGLPSVSLDPPRLSIQKDILTIMANTTLQITCRGQRDLD
WLWPNNQSGSEKRVEVTDCSDSFFCKTLTIPKVIGNDTGAYKCFYQDTDVASVIYVYVQD
YRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYKIYDVVLSPPHGVELSVGE
RLVLNCTARTELNVGIDFNWEYPSLKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGWYTCAASSGLMTKRNSTFVRVHEKPFVAFGSGMESLVEAIVGDRVRVPVKYLGYPPP
EIKWYKNGRPIESNHTIKVGHVLTIMEVSEKDTGNYTVILTNPISKEKQSHVVSLVVNVP
PQIGEKSLISPVDSYQYGTTQTLTCTVYAVPPPHHIRWYWQLEEECAYRPAQAVLMTNPY
TCKEWRNVDDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKAGRGE
RVISFHVTRGPEITLQPGTQPTEQERVSLWCTADRTTFENLTWYKAGSQALPVHVGELPT
PICKNLDALWKMNATTFSNGTSDTLILELQNASLQDQGDYVCFAQDRKTKKRHCVVRQLT
VLERVAPMITGNLENQTTSIGETIEVSCTTSGNPPPQITWFKDNETLVEDSGIVLKDGNR
NLTIRRVRKEDEGLYTCRACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWL
LLVIVLRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVN
LLGACTKPGGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKTKGARFRQGKEYVGEITMDPK
RRLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLA
SRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDR
VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTML
DCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVS
CMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDSQTDS
GMVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNHTSGYQSGYHSDDTDTTVYS
SEEAELLKLVEIGPQAGSAAQILQPDSGPALGSPPV
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctgctggccgtcgttctgtggttctgcgtggagacccgggctgcc
tctgtgggtttgcctagtgtttcccttgatccacccagactcagcatacaaaaagacata
cttacaattatggctaatacaactcttcagattacttgcaggggacagagggacttggac
tggctctggcccaacaatcagagtggctctgagaagagagtggaggtgacggactgcagt
gacagcttcttctgtaagacgctcacgattccaaaagtgatcggaaatgatactggagcc
tacaagtgcttctaccaggacactgacgtagcctcggtcatttatgtctatgttcaagat
tacaggtctccatttattgcttctgttagcgaccaacatggcgttgtgtacatcactgag
aacaaaaacaaaactgtggtgattccatgtcttgggtccatttccaacctcaatgtgtca
ctttgtgcaaggtatccagaaaagaggtttgtccctgatggtaacagaatttcctgggac
agtaagaaaggctttactatccccagctacatgatcagctatgctggcatggtcttctgt
gaagcaaaaattaatgatgaaagttaccagtctattatgtacatagttgtggttgtaggg
tacaagatttatgatgtggttctgagcccccctcatggagttgagctgtctgttggagag
aggctcgtcttaaactgtacagcgaggactgaactaaatgtggggattgacttcaactgg
gaatacccttctttgaagcatcagcataaaaagcttgttaaccgggacctaaaaactcaa
tctgggagtgagatgaagaaatttttgagcaccttgaccatagatggtgtaacccggagt
gaccaagggtggtatacctgtgcggcttccagtgggctgatgaccaagcggaacagcacg
ttcgtcagggtccacgaaaaaccttttgtcgcttttggtagtggcatggaatctttggtg
gaagccatcgtgggagaccgtgtcagagtgcctgtgaagtaccttggttaccctcccccg
gaaataaaatggtataaaaatggaagacccattgagtccaatcacacaataaaagtgggg
catgtactgactattatggaagtgagtgaaaaagatacaggaaattacactgtcatcctt
accaaccccatttcgaaggagaaacagagccacgtggtatctctggtcgtgaatgtccca
ccccagatcggcgagaaatccctgatctctccggtggattcataccagtacggcaccacg
caaacgctgacgtgcacggtctacgcggtccccccgccacatcacatccgctggtactgg
cagctggaggaggagtgtgcctacaggcctgcccaagctgtcttaatgacaaacccatac
acttgtaaagaatggagaaatgtggatgacttccaggggggaaataaaattgaagtcaac
aaaaatcaatttgccctaattgaaggaaaaaacaaaactgtaagtacccttgttatccaa
gcggcaaatgtgtcagctttgtacaaatgtgaagccgtcaacaaagctgggagaggagag
agggttatctccttccacgtgaccaggggccctgaaatcactttgcagcccggcacccag
ccgaccgaacaggaacgggtgtctttgtggtgcactgcagacagaactacatttgagaac
ctcacgtggtacaaggctggctctcaggctctgccagtccacgtgggagagctgcctaca
cccatctgcaagaacttggatgccctttggaaaatgaatgccaccacgttctctaatggc
acaagcgacactttgatcctggagctccagaacgcatccttgcaggaccaaggagattat
gtgtgctttgctcaggacaggaagaccaagaaaagacattgtgtggtccgacagctcacg
gttttagagcgtgtggcacccatgatcacaggaaacctggagaatcaaacaacaagtatt
ggtgaaaccatcgaagtttcgtgcaccacgtctgggaatccccctccacagattacgtgg
tttaaagataatgaaacacttgttgaagactcaggtattgtactgaaagatgggaaccgg
aacctaaccatccgcagggtgaggaaggaagatgaaggcctgtatacgtgccgggcatgc
agtgttcttgggtgtgcaaaagtggaggcatttttcatcgtggaaggtgcccaggagaag
acgaacttggaggtcattattctagtaggcacagcagtgattgccatgttcttctggtta
ttacttgtcatcgttctacggaccgttaagcgggccaatggaggggaactgaagacaggc
tacttgtccatcgtcatggatccagatgaactgcccttggatgaacactgtgaacgtctg
ccttatgatgccagcaagtgggaatttcccagagaccggctgaaactaggtaagcccctt
ggccgtggtgccttcggccaagtgatcgaagcagatgcctttggaattgacaagacagcg
acttgcaagacagtggctgtcaaaatgttaaaagaaggagccacacacagtgaacaccga
gccctcatgtctgaactcaagatcctcattcatattggccaccatctcaatgtggtcaat
cttctaggtgcctgtaccaagccaggagggccactcatggtgattgtggaattttgcaag
tttggaaacctgtcaacttacttaaggggcaagagaaatgaatttgtcccttacaagacc
aaaggggcacgatttcgtcaagggaaggaatacgttggggaaatcactatggatccgaaa
cgccgtttggatagtatcacgagtagtcagagctcagccagctctggatttgttgaggag
aaatccctcagtgatgtggaggaagaggaagtttctgaagatctgtacaagaacttcctg
accttggagcatctcatctgttacagcttccaagtggctaagggcatggagtttttggcg
tcacggaagtgtatccacagggacctggcggcacgaaatatcctcttgtcggagaagaac
gtggttaaaatctgtgactttggcttggcccgggatatttataaagacccagattatgtc
agaaaaggagatgctcgcctccctttgaaatggatggccccagaaacgatttttgaccga
gtgtacacaattcagagtgatgtgtggtcttttggtgttttgctttgggaaatattttcc
ttaggtgcttctccatatcctggagtaaagattgatgaggaattttgtaggcgattgaaa
gaaggcactagaatgagggcccctgattataccacaccagaaatgtaccagaccatgctt
gactgctggcatggggagcccagtcagagacccacgttttctgagttggtggaacatttg
ggaaatctcttacaagctaatgctcagcaggatggcaaagactatattgttctcccgata
tcagagactttgagcatggaagaggattctggactctctctgcctacctcacctgtttcc
tgtatggaggaagaggaagtgtgtgaccccaaattccattatgacaacacagcaggaatc
agtcagtatctgcagaacagtaagcgaaagagccggcccgtgagtgtaaaaacatttgaa
gatatcccgttggaagaaccagaagtaaaagtaatcccagatgacagccagacggacagt
ggtatggttcttgcatcagaagagctgaaaaccttggaagacagaaccaaattagctcca
tcttttagtggactgatgcccagcaaaagcaaggagtccgtggcatccgaaggctccaac
cacacgagtggctaccagtccgggtatcactccgatgacacagacaccactgtgtactcc
agcgaggaggcagaacttttaaagctggtggagattggaccacaagctggcagtgcagcc
cagattctccagcctgactctggacccgcgttgggctctcctcctgtttaa
DBGET
integrated database retrieval system
