KEGG   Pelagovum pacificum: I8N54_10200
Entry
I8N54_10200       CDS       T06971                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
ppaf  Pelagovum pacificum
Pathway
ppaf00860  Porphyrin metabolism
ppaf01100  Metabolic pathways
ppaf01110  Biosynthesis of secondary metabolites
ppaf01120  Microbial metabolism in diverse environments
ppaf01240  Biosynthesis of cofactors
Module
ppaf_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:ppaf00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    I8N54_10200 (cobA)
Enzymes [BR:ppaf01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     I8N54_10200 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     I8N54_10200 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     I8N54_10200 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Other DBs
NCBI-ProteinID: QQA44961
LinkDB
Position
2074909..2076303
AA seq 464 aa
MQHFPIFLNLRGRRVVLSGGGECALAKLRLILKSEAEVVVYADAPVTELEDWAQGGKLTL
VRRPMNRGDAKGAALFYAANDDPTEDARVAAIADAEGVLVNVVDNLRDSQFITPAIVDRD
PVTVAIGTEGAAPVLARAIKADLEARLPVQLGTLARIGKAFRKAADALPMGRKRRDFWRD
YYFAEGPRAIEQGEDEVTPALKALLDRHLAADARVGHVDFVGAGPGDPELLTLKARKALD
EADVIIHDRLIAPEILELARREAVLVEAGKEGFGPSVSQDDINAMIVAEAQQGHQVVRLK
SGDPTVFGRLDEEIDACDAAAISWRVVPGITAASAAVAAVGQSLTKRDRNSSVRLLTGHD
MKGFAEHDWKALARPGEVAAIYMGKKTARFVQGRLLMHGADPATPVSVVENASRADQRVL
ACTLGELEPTLSDAALAGPALILFGLAPRRAELIARDFDRMEQA
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgcagcactttccgatcttcctcaatcttcgcggccgccgcgttgtcctgtcgggcggc
ggcgagtgcgcgctggccaagctgcgcctgatcctgaagtccgaggccgaggtcgtcgtc
tatgcagacgcgcccgtgaccgaactggaggactgggcgcagggcggcaaactgacgctg
gtccgcaggccgatgaaccggggcgacgcgaaaggcgccgcgctgttctacgccgccaac
gacgatccgaccgaggatgcccgggtcgccgccatcgccgacgccgaaggtgtgctggtc
aacgtcgtggacaatctccgcgacagccagttcatcacgcccgccatcgtcgaccgcgac
ccggtcacggtcgccatcggcaccgagggcgccgcccccgtgctggcccgcgccatcaag
gcggacctcgaagcgcggcttccggttcagctcggcacgctggcgcggatcggcaaggcc
ttccgcaaggcggccgacgcgttgccgatgggccgcaagcgccgcgacttctggcgcgac
tattacttcgccgagggcccccgtgccatcgagcagggcgaggacgaggtgacaccggcc
ctgaaggcgctgctcgaccggcatcttgccgcggatgcgcgcgtcggccacgtcgacttc
gtcggtgccggtccgggcgatccggagcttctgacgctgaaggcgcgcaaggcgctcgac
gaggcggacgtcatcatccacgaccggctgatcgcgcccgagatcctcgagctcgcccgt
cgcgaggcggtgctggtcgaggccggcaaggaaggcttcggcccctccgtcagccaagac
gacatcaacgccatgatcgtcgcggaggcgcagcagggccaccaggtggtccggctgaaa
tccggcgatccgaccgtcttcggccggctcgacgaggagatcgacgcctgtgacgccgcc
gcgatcagctggcgcgtcgtgccgggcatcacggcggcgtccgccgccgttgccgccgtg
ggtcagagcctgaccaaacgcgaccggaactcgtccgtgcggctgctgaccggacacgac
atgaagggcttcgccgagcatgactggaaggcgctcgcccgtcccggcgaagtcgccgcg
atctacatgggcaagaagaccgcccgtttcgtgcagggccggctgctgatgcacggcgcc
gatcccgccacgcccgtaagcgtcgtggagaacgccagccgcgccgatcagcgcgtgctc
gcctgcacccttggcgagctggagccgaccctgtcggacgccgcgctcgccggccccgcc
ctgatcctcttcggcctcgccccgcgccgggccgaactcatcgcccgcgatttcgaccgg
atggagcaagcctga

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