KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129064134
Entry
129064134         CDS       T09558                                 
Name
(RefSeq) son of sevenless homolog 2 isoform X1
  KO
K03099  son of sevenless
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521  EGFR tyrosine kinase inhibitor resistance
ppam01522  Endocrine resistance
ppam04010  MAPK signaling pathway
ppam04012  ErbB signaling pathway
ppam04014  Ras signaling pathway
ppam04062  Chemokine signaling pathway
ppam04068  FoxO signaling pathway
ppam04072  Phospholipase D signaling pathway
ppam04150  mTOR signaling pathway
ppam04151  PI3K-Akt signaling pathway
ppam04510  Focal adhesion
ppam04540  Gap junction
ppam04630  JAK-STAT signaling pathway
ppam04650  Natural killer cell mediated cytotoxicity
ppam04660  T cell receptor signaling pathway
ppam04662  B cell receptor signaling pathway
ppam04664  Fc epsilon RI signaling pathway
ppam04714  Thermogenesis
ppam04722  Neurotrophin signaling pathway
ppam04810  Regulation of actin cytoskeleton
ppam04910  Insulin signaling pathway
ppam04912  GnRH signaling pathway
ppam04915  Estrogen signaling pathway
ppam04917  Prolactin signaling pathway
ppam04926  Relaxin signaling pathway
ppam04935  Growth hormone synthesis, secretion and action
ppam05034  Alcoholism
ppam05160  Hepatitis C
ppam05161  Hepatitis B
ppam05163  Human cytomegalovirus infection
ppam05165  Human papillomavirus infection
ppam05200  Pathways in cancer
ppam05205  Proteoglycans in cancer
ppam05206  MicroRNAs in cancer
ppam05207  Chemical carcinogenesis - receptor activation
ppam05208  Chemical carcinogenesis - reactive oxygen species
ppam05210  Colorectal cancer
ppam05211  Renal cell carcinoma
ppam05213  Endometrial cancer
ppam05214  Glioma
ppam05215  Prostate cancer
ppam05220  Chronic myeloid leukemia
ppam05221  Acute myeloid leukemia
ppam05223  Non-small cell lung cancer
ppam05224  Breast cancer
ppam05225  Hepatocellular carcinoma
ppam05226  Gastric cancer
ppam05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129064134
   04012 ErbB signaling pathway
    129064134
   04014 Ras signaling pathway
    129064134
   04630 JAK-STAT signaling pathway
    129064134
   04068 FoxO signaling pathway
    129064134
   04072 Phospholipase D signaling pathway
    129064134
   04151 PI3K-Akt signaling pathway
    129064134
   04150 mTOR signaling pathway
    129064134
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129064134
   04540 Gap junction
    129064134
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129064134
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    129064134
   04660 T cell receptor signaling pathway
    129064134
   04662 B cell receptor signaling pathway
    129064134
   04664 Fc epsilon RI signaling pathway
    129064134
   04062 Chemokine signaling pathway
    129064134
  09152 Endocrine system
   04910 Insulin signaling pathway
    129064134
   04912 GnRH signaling pathway
    129064134
   04915 Estrogen signaling pathway
    129064134
   04917 Prolactin signaling pathway
    129064134
   04926 Relaxin signaling pathway
    129064134
   04935 Growth hormone synthesis, secretion and action
    129064134
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    129064134
  09159 Environmental adaptation
   04714 Thermogenesis
    129064134
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129064134
   05206 MicroRNAs in cancer
    129064134
   05205 Proteoglycans in cancer
    129064134
   05207 Chemical carcinogenesis - receptor activation
    129064134
   05208 Chemical carcinogenesis - reactive oxygen species
    129064134
   05231 Choline metabolism in cancer
    129064134
  09162 Cancer: specific types
   05210 Colorectal cancer
    129064134
   05225 Hepatocellular carcinoma
    129064134
   05226 Gastric cancer
    129064134
   05214 Glioma
    129064134
   05221 Acute myeloid leukemia
    129064134
   05220 Chronic myeloid leukemia
    129064134
   05211 Renal cell carcinoma
    129064134
   05215 Prostate cancer
    129064134
   05213 Endometrial cancer
    129064134
   05224 Breast cancer
    129064134
   05223 Non-small cell lung cancer
    129064134
  09172 Infectious disease: viral
   05161 Hepatitis B
    129064134
   05160 Hepatitis C
    129064134
   05163 Human cytomegalovirus infection
    129064134
   05165 Human papillomavirus infection
    129064134
  09165 Substance dependence
   05034 Alcoholism
    129064134
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129064134
   01522 Endocrine resistance
    129064134
SSDB
Motif
Pfam: RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH IQ_SEC7_PH RHG20_PH PH_19
Other DBs
NCBI-GeneID: 129064134
NCBI-ProteinID: XP_054421185
LinkDB
Position
Unknown
AA seq 1332 aa
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVAQYFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKTQICDKEDTCEYKHAFELISKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRLA
AEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGVSHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDNDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGALDGPL
HSPPPPPPRDPLPDSPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVGTCPNSPN
TPPSTPSPRVPRRCYMLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENTETPQ
NT seq 3999 nt   +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtacatccgaatctctcagct
aatgaagaatctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaatcgataaatgggctatagctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcactgaaggaagttttagggtac
aaagtggactaccatgtgtccttatatatcgtggctgtactagagtatatctcagctgat
attttgaaattagctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagctcttcaggtgaattaaactactat
gaccttgtcaggactgaaattgcagaagaaagacagtatctgcgggaactaaatatgatc
ataaaagtgtttagagaagcctttctttctgacaaaaagttgtttaaaccttctgacatt
gaaaagattttcagtaacatttcagatatacatgagttgacagtaaaacttttagggttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccaaagtttaatgaacatttcagtaagttgatggccagacctgcagtggctcaa
tactttcagtccattgctgatggttttagagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtgtatcactgttggcactattttgaattactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagcgattactgctctcatgaac
ctccaaggtagtatggaccgaatttacaagcaatattcacctcgacgccgacctggggat
cctgtttgccctttttataaccgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggtccattgacaagaattggtgctaaacatgaacggcatatattt
ctctttgatggtttaatgattagctgcaaacccaatcatagccagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagaaaaatttgtcatgagaaaaacacaaatatgt
gataaagaagatacttgtgagtacaaacatgcttttgaattgatatccaaagatgaaaac
agcataatatttgctgctaagtctgcagaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattattaaaagaagaa
aatgagcaaccgctgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaacggtggtgaagttaattgaaagattaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaactgctaagc
ttactgattgaacggtttgaaattccagagccagaacctactgaagcagatagattggca
gcagagaaaggcgaacaaccaattagcgcagaccttaaaaggtttcgtaaggaatacgtc
caaccagtacaacttaggatcctaaatgtatttcggcactgggttgaacaccatttttat
gactttgaaagggatttggagttgcttgaaaggctagaatccttcatttcaagtgtaaga
gggaaagccatgaagaaatgggtagagtcaattgctaaaatcatcaaaagaaagaaacaa
gctcaggcaaatggagtaagccataatattacctttgaaagtccaccaccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcagccttct
gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgtcatactacaaatcttacactctggtttgaaaagtgcattgtggaagcg
gaaaattttgaggaacgggtggcaatactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagatcatacctttgaggcattgcaggaaaggaaaaggagaattttggat
gaagctgtggaattaagtcaggatcactttaaaaaatacctagcaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatacttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtggctgaaattactggagaaattcagcagtatcagaatcaaccttattgtttacgg
atagaaccagaaataaggcggttctttgaaaaccttaaccccatgggaagtgcttctgaa
aaagagtttacagattatttgttcaataaatcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcccaggaaatcaactttctctttaaaatctcctggaataaggcct
aatgcaggccgacatggctctacctcaggcactttaagaggtcatccaacaccgttagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagcttgaatcaacagtg
tcggcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtagatctcaacagttcctgtggcagcaatagcatctttgctcca
gttctcttgccacattcaaagtctttcttcagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcggaaaaaatttgataatgatgcttca
aattccaagggaaacatgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacccagagttcctgttcctactggtgcacttgatgggccgctg
catagtccacctccaccgccaccgagagaccctcttcctgatagccctccaccggttccc
cttcggcctccggaacactttataaactgtccgtttaatcttcagccacctccgctggga
catcttcacagagatccagactggttcagagatgttggcacgtgtccaaattcgccaaac
actcctcctagcacaccctctccaagggtgccacgtcgatgctatatgctcagttctagt
cacaataatctggctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaacacggaaactcctcaatga

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